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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2022 Volume 23 Issue 4

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Impact Factor: 2.2

Article Open Access

Vitamin D receptor deficiency increases systolic blood pressure by upregulating the renin‑angiotensin system and autophagy

Jian Jia, Xu Tao, Zhouning Tian, Jing Liu, Xiaoman Ye, Yiyang Zhan
Article Number: 314
Published online on: 01 March 2022

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Article Open Access

Glaucocalyxin A alleviates lipopolysaccharide‑induced inflammation and apoptosis in pulmonary microvascular endothelial cells and permeability injury by inhibiting STAT3 signaling

Jianwei Cao, Meiling Liu, Shufang Feng, Yingying Li, Kaijun Zheng
Article Number: 313
Published online on: 01 March 2022

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Retraction Open Access

[Retracted] MicroRNA‑124 inhibits cell proliferation, invasion and migration by targeting CAV1 in bladder cancer

Wandan Zhou, Leye He, Yinbo Dai, Yichuan Zhang, Jinrong Wang, Bin Liu
Article Number: 312
Published online on: 01 March 2022

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Article Open Access

A novel KLF13 mutation underlying congenital patent ductus arteriosus and ventricular septal defect, as well as bicuspid aortic valve

Pradhan Abhinav, Gao-Feng Zhang, Cui-Mei Zhao, Ying-Jia Xu, Juan Wang, Yi-Qing Yang
Article Number: 311
Published online on: 01 March 2022

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Article Open Access

Exogenous spermine inhibits high glucose/oxidized LDL‑induced oxidative stress and macrophage pyroptosis by activating the Nrf2 pathway

Yuxuan Qiu, Linna Li, Xiaohui Guo, Jiangwen Liu, Liang Xu, Yanbo Li
Article Number: 310
Published online on: 01 March 2022

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Article

miR‑216a‑3p inhibits osteogenic differentiation of human adipose‑derived stem cells via Wnt3a in the Wnt/β‑catenin signaling pathway

Daning Liang, Guodong Song, Zhenning Zhang
Article Number: 309
Published online on: 24 February 2022

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Article Open Access

Ganoderic acid A ameliorates non‑alcoholic streatohepatitis (NASH) induced by high‑fat high‑cholesterol diet in mice

Jing Zhu, Jiexia Ding, Siying Li, Jie Jin
Article Number: 308
Published online on: 24 February 2022

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Article Open Access

Mitochondrial dynamics and biogenesis indicators may serve as potential biomarkers for diagnosis of myasthenia gravis

Lanqi Li, Donghong Cai, Huiya Zhong, Fengbin Liu, Qilong Jiang, Jian Liang, Peiwu Li, Yafang Song, Aidong Ji, Wei Jiao, Jingwei Song, Jinqiu Li, Zhiwei Chen, Qing Li, Lingling Ke
Article Number: 307
Published online on: 24 February 2022

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Article Open Access

Transformation of nomifensine using ionizing radiation and exploration of its anticancer effects in MCF‑7 cells Expression of Concern in /10.3892/etm.2026.13276

Seong Hee Kang, Dong-Ho Bak, Byung Yeoup Chung, Hyoung-Woo Bai
Article Number: 306
Published online on: 23 February 2022

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Article Open Access

Application of machine learning tools: Potential and useful approach for the prediction of type 2 diabetes mellitus based on the gut microbiome profile

Xiaochun Ge, Aimin Zhang, Lihui Li, Qitian Sun, Jianqiu He, Yu Wu, Rundong Tan, Yingxia Pan, Jiangman Zhao, Yue Xu, Hui Tang, Yu Gao
Article Number: 305
Published online on: 23 February 2022

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Article Open Access

Pterostilbene attenuates the proliferation and differentiation of TNF‑α‑treated human periodontal ligament stem cells

Min Yi, Guanglei Wang, Jianhua Niu, Minghui Peng, Yi Liu
Article Number: 304
Published online on: 22 February 2022

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Article Open Access

Sevoflurane preconditioning prevents acute renal injury caused by ischemia‑reperfusion in mice via activation of the Nrf2 signaling pathway

Wen-Xi Wang, Zhen-Ru Zhao, Ying Bai, Ya-Xing Li, Xiao-Ning Gao, Sen Zhang, Yan-Bin Sun
Article Number: 303
Published online on: 22 February 2022

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Article Open Access

Shp2 suppresses fat accumulation in white adipose tissue by activating Wnt/β‑catenin signaling following vertical sleeve gastrectomy in obese rats with type‑2 diabetes

Xiaoyang Qi, Ziying Sun, Xugang Li, Yuwen Jiao, Shuai Chen, Peng Song, Zhifen Qian, Jun Qian, Xusheng Qiu, Liming Tang
Article Number: 302
Published online on: 22 February 2022

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Article Open Access

Assessing the anti‑inflammatory effects of quercetin using network pharmacology and in vitro experiments

Jingwen Zhang, Hongyan Li, Wei Wang, Hong Li
Article Number: 301
Published online on: 22 February 2022

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Article Open Access

Rosiglitazone ameliorates acute hepatic injury via activating the Nrf2 signaling pathway and inhibiting activation of the NLRP3 inflammasome

Ling Ma, Ying Ma, Bin-Xi Ma, Ming Ma
Article Number: 300
Published online on: 21 February 2022

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Article Open Access

Bone resorption improvement by conditioned medium of stem cells from human exfoliated deciduous teeth in ovariectomized mice

Ayako Maeda, Takashi Kikuiri, Yoshitaka Yoshimura, Yasutaka Yawaka, Tetsuo Shirakawa
Article Number: 299
Published online on: 21 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑302 inhibits cell migration and invasion in cervical cancer by targeting DCUN1D1

Yongjie Jiang, Ruijie Hou, Shaoping Li, Shaoru Li, Ge Dang
Article Number: 298
Published online on: 21 February 2022

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Article Open Access

Second endoscopic retrograde cholangiopancreatography after failure of initial biliary cannulation: A single institution retrospective experience

Xin Deng, Rui Liao, Long Pan, Chengyou Du, Qiao Wu
Article Number: 297
Published online on: 18 February 2022

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Article Open Access

Gastrodin attenuates lipopolysaccharide‑induced inflammation and oxidative stress, and promotes the osteogenic differentiation of human periodontal ligament stem cells through enhancing sirtuin3 expression

Qiujing Feng
Article Number: 296
Published online on: 18 February 2022

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Article Open Access

Circular RNA hsa_circ_0011946 promotes the malignant process of salivary adenoid cystic carcinoma by downregulating miR‑1205 expression

Huiping Wei, Jun Li, Cheng Xie, Hao Dong
Article Number: 295
Published online on: 18 February 2022

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Article

Prognostic factors for the safety and efficacy of retrograde laser lithotripsy: Data from a contemporary series of 155 consecutive patients with single and multiple lithiasis of the urinary tract

Diomidis Kozyrakis, Georgios Soukias, Dimitrios Karagiannis, Anastasios Zarkadas, Stefanos Perikleous, Styliani-Elissavet Chatzistamou, Ilias Katsaros, Konstantinos Skriapas, Michael Lardas, Nikolaos Mertziotis, Zisis Kratiras
Article Number: 294
Published online on: 17 February 2022

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Article Open Access

Tilianin attenuates MPP+‑induced oxidative stress and apoptosis of dopaminergic neurons in a cellular model of Parkinson's disease

Jie Li, Sui Xu
Article Number: 293
Published online on: 17 February 2022

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Article

Omentin inhibits the resistin‑induced hypertrophy of H9c2 cardiomyoblasts by inhibiting the TLR4/MyD88/NF‑κB signaling pathway

Xiaoliang Yan, Lin Wu, Min Gao, Pengjie Yang, Jinjing Yang, Yongzhi Deng
Article Number: 292
Published online on: 17 February 2022

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Article Open Access

S100A9 blockade improves the functional recovery after spinal cord injury via mediating neutrophil infiltration

Feng Sun, Haiwei Zhang, Tianwen Huang, Jianhui Shi, Tianli Wei, Yansong Wang
Article Number: 291
Published online on: 17 February 2022

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Article Open Access

Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia‑induced pancreatitis in vitro

Hui-Ying Yang, Zhi-Hai Liang, Jin-Lian Xie, Qing Wu, Ying-Ying Qin, Shi-Yu Zhang, Guo-Du Tang
Article Number: 290
Published online on: 16 February 2022

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Case Report Open Access

An integrative therapeutic approach to elephantiasis nostras verrucosa: A case report

Lawrence Chukwudi Nwabudike, Olimpia Buzia, Alina Mihaela Elisei, Alin Laurentiu Tatu
Article Number: 289
Published online on: 16 February 2022

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Review

Diabetes mellitus: Plasticizers and nanomaterials acting as endocrine‑disrupting chemicals (Review)

Mihaela Jana Tuculina, Paula Perlea, Mircea Gheorghiță, Cristian Niky Cumpătă, Ionela Teodora Dascălu, Adina Turcu, Andreea Gabriela Nicola, Lelia Mihaela Gheorghiță, Oana Andreea Diaconu, Ana Valea, Adina Ghemigian, Mara Carsote
Article Number: 288
Published online on: 16 February 2022

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Review

Adrenocortical carcinoma: Pediatric aspects (Review)

Florica Sandru, Răzvan-Cosmin Petca, Mara Carsote, Aida Petca, Mihai Cristian Dumitrascu, Adina Ghemigian
Article Number: 287
Published online on: 16 February 2022

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Article Open Access

Expression of TMED3 is independently associated with colorectal cancer prognosis

Rong-Fei Wang, Yong-Gang Hong, Li-Qiang Hao, Hai-Tao Yu
Article Number: 286
Published online on: 15 February 2022

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Article Open Access

Effects of vitamin D with or without calcium on pathological ossification: A retrospective clinical study

Libin Liang, Tong Tong, Luyang Qin, Jing Xie, Yanping Xu, Yuguo Qin, Lansen Zhang, Dehui Liu, Xiaoyun Niu, Xinglong Tong
Article Number: 285
Published online on: 15 February 2022

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Article Open Access

pH regulates the lumen diameter of tissue‑engineered capillaries

Xiaolin Wang, Jing Li, Yongqian Bian, Congying Zhao, Jinqing Li, Xueyong Li
Article Number: 284
Published online on: 15 February 2022

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Article Open Access

miR‑150‑5p inhibits osteogenic differentiation of fibroblasts in ankylosing spondylitis by targeting VDR

Yuan Li, Wufang Qi, Yuquan Shi
Article Number: 283
Published online on: 15 February 2022

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Article Open Access

Anagliptin promotes apoptosis in mouse colon carcinoma cells via MCT‑4/lactate‑mediated intracellular acidosis

Qi Li, Xiaoling Qin, Xiaotong Kou, Jingyu Li, Zhongsha Li, Chang Chen
Article Number: 282
Published online on: 15 February 2022

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Article Open Access

MicroRNA‑200a‑3p and GATA6 are abnormally expressed in patients with non‑small cell lung cancer and exhibit high clinical diagnostic efficacy

Jie Yu, Xinyun He, Chunju Fang, Haixia Wu, Lei Hu, Yingbo Xue
Article Number: 281
Published online on: 15 February 2022

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Retraction Open Access

[Retracted] Long non‑coding RNA TUG1 promotes osteosarcoma cell proliferation and invasion through inhibition of microRNA‑212‑3p expression

Heng Li, Guofeng Tian, Feipeng Tian, Lin Shao
Article Number: 280
Published online on: 14 February 2022

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Article Open Access

Effects and early diagnostic value of lncRNA H19 on sepsis‑induced acute lung injury

You Zhou, Liqun Sun, Mingyu Zhu, He Cheng
Article Number: 279
Published online on: 14 February 2022

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Article Open Access

Micropulse vs. continuous wave transscleral cyclophotocoagulation in neovascular glaucoma

Mihail Zemba, Otilia-Maria Dumitrescu, Florin Vaida, Elena-Andreea Dimirache, Iulia Pistolea, Alina Cristina Stamate, Marian Burcea, Daniel Constantin Branisteanu, Florian Balta, Ileana Ramona Barac
Article Number: 278
Published online on: 11 February 2022

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Article Open Access

Monomeric C‑reactive protein level is associated with osteoarthritis

Yulin Liang, Ke Xu, Wenguang Liu, Xiaoling Liu, Ping Yuan, Peng Xu, Haiyun Li
Article Number: 277
Published online on: 11 February 2022

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Article Open Access

Nephroprotective effect of magnesium isoglycyrrhizinate against arsenic trioxide‑induced acute kidney damage in mice

Ziheng Wei, Xiaoqi Sun, Qianqian He, Yang Zhao, Yongchao Wu, Xue Han, Zhonglin Wu, Xi Chu, Shengjiang Guan
Article Number: 276
Published online on: 11 February 2022

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Article Open Access

Kidney and lung injury in rats following acute diquat exposure

Yuzheng Wu, Siqi Cui, Wenjun Wang, Tianzi Jian, Baotian Kan, Xiangdong Jian
Article Number: 275
Published online on: 11 February 2022

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Article Open Access

Indigo plant leaf extract inhibits the binding of SARS‑CoV‑2 spike protein to angiotensin‑converting enzyme 2

Man Hagiyama, Fuka Takeuchi, Aki Sugano, Azusa Yoneshige, Takao Inoue, Akihiro Wada, Hiroshi Kajiyama, Yutaka Takaoka, Kenroh Sasaki, Akihiko Ito
Article Number: 274
Published online on: 10 February 2022

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Article Open Access

Role of HSP90α in osteoclast formation and osteoporosis development

Jianli Ma, Chen Yang, Huajian Zhong, Cheng Wang, Ke Zhang, Xiaoming Li, Jinhui Wu, Yang Gao
Article Number: 273
Published online on: 10 February 2022

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Article Open Access

Curcumin ameliorates H2O2‑induced inflammatory response in chondrocytes by inducing autophagy activation

Hai-Liang Qi, Zheng-Yi Chen, Yu-Huan Qin, Ya-Zhai Li
Article Number: 272
Published online on: 09 February 2022

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Review Open Access

Role of melatonin in respiratory diseases (Review)

Lijie Li, Xiaochao Gang, Jiajia Wang, Xiaoyan Gong
Article Number: 271
Published online on: 09 February 2022

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Review

New approaches in predicting and diagnosing preeclampsia: Congo Red Dot Paper Test (Review)

Aida Petca, Ruxandra Diana Sinescu, Florica Sandru, Razvan-Cosmin Petca, Mihai Cristian Dumitrascu, Claudia Mehedintu, Mona Elena Zvanca
Article Number: 270
Published online on: 08 February 2022

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Case Report Open Access

Paget's disease of bone and megaloblastic anemia in a 72‑year‑old patient: A case report and systematic literature review

Violeta Diana Oprea, Violeta Claudia Bojincă, Andra-Rodica Bălănescu, Alin Laurențiu Tatu, Mihai Bojincă, Aurelia Romila
Article Number: 269
Published online on: 08 February 2022

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Case Report

A mesorectal incidentaloma: Rare localization of Castleman disease (Case report)

Daniel Ion, Alexandra Bolocan, Alexandru George Filipescu, Octavian Andronic, Ana-Maria Oproiu, Adelina Popa, Dan Nicoale Păduraru
Article Number: 268
Published online on: 08 February 2022

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Article Open Access

Sirtuin 1 participates in intervertebral disc degeneration via the nicotinamide phosphoribosyl transferase/nicotinamide adenine dinucleotide/sirtuin 1 pathway responsible for regulating autophagy of nucleus pulposus cells

Qifeng Shi, Liang Xu, Xiangyi Zeng
Article Number: 267
Published online on: 08 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑153 functions as a tumor suppressor in gastric cancer via targeting Kruppel‑like factor 5

Yanlan Ouyang, Weijie Yuan, Sainan Qiu
Article Number: 266
Published online on: 07 February 2022

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Article Open Access

Inhibition of Sestrin2 overexpression in diabetic cardiomyopathy ameliorates cardiac injury via restoration of mitochondrial function

Xiaodan Zhang, Xiaoyi Deng, Huiyu Ye, Zhishan Chen, Wangen Li
Article Number: 265
Published online on: 04 February 2022

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Article Open Access

Bioresonance, an alternative therapy for mild and moderate depression

Daniela Muresan, Septimiu Voidăzan, Andreea Salcudean, Cristina Raluca Bodo, Iosif Gabos Grecu
Article Number: 264
Published online on: 04 February 2022

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Article

Understanding orthopedic infections through a different perspective: Microcalorimetry growth curves

Mihnea Popa, Adrian Cursaru, Vlad Popa, Alexandru Munteanu, Bogdan Șerban, Bogdan Crețu, Sergiu Iordache, Catalin Gabriel Smarandache, Carmen Orban, Cătălin Cîrstoiu
Article Number: 263
Published online on: 04 February 2022

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Review Open Access

Clinical impact of wireless capsule endoscopy for small bowel investigation (Review)

Alin Gabriel Ionescu, Adina Dorina Glodeanu, Mihaela Ionescu, Sorin Ioan Zaharie, Ana Maria Ciurea, Andreea Loredana Golli, Nikolaos Mavritsakis, Didi Liliana Popa, Cristin Constantin Vere
Article Number: 262
Published online on: 04 February 2022

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Article

Neurological manifestations found in children with multisystem inflammatory syndrome

Cristina Maria Mihai, Tatiana Chisnoiu, Claudia Simona Cambrea, Corina Elena Frecus, Larisia Mihai, Adriana Luminita Balasa, Alina Zorina Stroe, Anca Elena Gogu, Any Docu Axelerad
Article Number: 261
Published online on: 04 February 2022

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Article

Role of hTERT rs2736100 in pathological scarring

Roxana Flavia Ilieș, Salomea-Ruth Halmagyi, Andreea Cătană, Casian Simon Aioanei, Istvan Lukacs, Reka-Eniko Tokes, Ioana Cristina Rotar, Ioan Victor Pop
Article Number: 260
Published online on: 04 February 2022

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Review Open Access

Phototherapy in dermatological maladies (Review)

Daciana Elena Branisteanu, Diana Stefania Dirzu, Mihaela Paula Toader, Daniel Constantin Branisteanu, Alin Codrut Nicolescu, Ilarie Brihan, Camelia Margareta Bogdanici, George Branisteanu, Andreea Dimitriu, Nicoleta Anton, Elena Andrese Porumb
Article Number: 259
Published online on: 03 February 2022

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Review Open Access

Mucocutaneous lesions associated with SARS‑CoV‑2 infection (Review)

Mihaela Paula Toader, Daniel Constantin Branisteanu, Mihai Glod, Irina Mihaela Esanu, Catalina Ioana Branisteanu, Maria-Stefana Capsa, Andreea Dimitriu, Alin Codrut Nicolescu, Alin Constantin Pinzariu, Daciana Elena Branisteanu
Article Number: 258
Published online on: 03 February 2022

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Case Report Open Access

Concomitance or consequence? Stevens‑Johnson syndrome in COVID‑19: A case report

Carmen Manciuc, Georgiana Alexandra Lacatusu, Andrei Vata, Cristina Sapaniuc, Carmen Mihaela Arteni, Florin Dumitru Petrariu
Article Number: 257
Published online on: 02 February 2022

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Article

Serum metabonomics as a diagnostic approach for cancer‑related fatigue

Haiming Wang, Tong Zhao, Can Lv, Zhan Zhang, Fanfu Fang, Bai Li
Article Number: 256
Published online on: 02 February 2022

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Review Open Access

Advantages and prospects of optical coherence tomography in interventional therapy of coronary heart disease (Review)

Jie Wang, Shuo Yuan, Jingjing Qi, Qinggao Zhang, Zheng Ji
Article Number: 255
Published online on: 02 February 2022

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Correction

Correlations between periodontal indices and osteoporosis

Smaranda Adelina Preda, Maria Cristina Comanescu, Dana Maria Albulescu, Ionela Teodora Dascălu, Adrian Camen, Cristian Niky Cumpătă, Paula Perlea, Narcis Mihăiță Bugălă, Elena Loredana Stoica, Lelia Mihaela Gheorghiță, Oana Andreea Diaconu, Mihaela Jana Tuculina
Article Number: 254
Published online on: 01 February 2022

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Cofilin‑1 as a potential biomarker for Mycobacterium tuberculosis infection

Yiping Xie, Zhiqin Zhang, Min Zhang, Hui Cao
Article Number: 253
Published online on: 01 February 2022

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Expression profile, clinical significance and biological functions of IGF2BP2 in esophageal squamous cell carcinoma

Fenying Lu, Weichang Chen, Tingwang Jiang, Cuie Cheng, Bin Wang, Zhiping Lu, Guojin Huang, Jiaming Qiu, Wei Wei, Ming Yang, Xia Huang
Article Number: 252
Published online on: 01 February 2022

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VEGF alleviates lower limb ischemia in diabetic mice by altering muscle fiber types

Lijing Jia, Peilin Zheng, Hongbo Wang, Lin Kang, Han Wu, Xiaobing Fu
Article Number: 251
Published online on: 31 January 2022

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[Retracted] Gut flora profiling and fecal metabolite composition of colorectal cancer patients and healthy individuals

Xiaoxue Wang, Jianping Wang, Benqiang Rao, Li Deng
Article Number: 250
Published online on: 31 January 2022

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Post‑treatment with propofol inhibits inflammatory response in LPS‑induced alveolar type II epithelial cells

Xilun Yang, Ling Ma
Article Number: 249
Published online on: 31 January 2022

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Melatonin alleviates traumatic brain injury‑induced anxiety‑like behaviors in rats: Roles of the protein kinase A/cAMP‑response element binding signaling pathway

Ling-Ling Xie, Shan-Shan Li, Yong-Jian Fan, Man-Man Qi, Zhuang-Zhuang Li
Article Number: 248
Published online on: 31 January 2022

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October-2026 Volume 32 Issue 4

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Promoting expertise knowledge sharing in paediatric virology: An update (Review)

Ioannis N. Mammas, Anna Kramvis, Anastasia Stouraiti, Tina Dalianis, Patra Koletsi, Georgia Papaioannou, Alexia Papatheodoropoulou, Chryssie Koutsaftiki, Paraskevi Korovessi, Simon B. Drysdale, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 293
Published online on: 07 September 2026

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ACT001 suppresses ox‑LDL‑mediated macrophage ferroptosis via activating the NRF2 pathway: An in vitro mechanistic study relevant to atherosclerosis

Yangyang Tao, Yuwu Chen, Yonghou Zhao, Jianbo Cai
Article Number: 292
Published online on: 07 September 2026

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From mitochondria to innate immunity: The mtDNA‑driven cGAS/STING‑NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)

Hui Liu, Yao Zhang, Ziliang Zhuo, Wei Zhong, Manyun Yan, Zhongbo Zhao
Article Number: 291
Published online on: 04 September 2026

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Active abdominal compression‑decompression cardiopulmonary resuscitation attenuates neuroinflammation associated with TLR4/NF‑κB signaling in a rat model of cardiac arrest

Xiaopeng Liu, Xiaoqing Yang, Yifan Huang, Xinyuan Kong, Jiankai Gao, Hongyu Wang, Sisen Zhang
Article Number: 290
Published online on: 04 September 2026

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ASF1A: A versatile histone chaperone bridging chromatin dynamics, disease mechanisms and clinical potential (Review)

Jun Yin, Xiaojian Zhuo, Lihui Wen, Xianmin Wang, Tongyong Luo, Qingsong Wang
Article Number: 289
Published online on: 02 September 2026

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Preventive administration of verapamil attenuates dextran sulfate sodium‑induced colitis in mice

Natsuki Ota, Keisuke Sato, Ryosuke Tatsunami
Article Number: 288
Published online on: 02 September 2026

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Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review)

Cong Yuan, Jiale Tong, Weiwei Qian, Qian He
Article Number: 287
Published online on: 02 September 2026

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Mapping and anatomo‑surgical techniques for language preservation in brain tumours (Review)

Xiaoyuan Liu, Jia Ouyang, Jiangfei Wang
Article Number: 286
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] Circular RNA expression profiles significantly altered in UVA‑irradiated human dermal fibroblasts

Mengbi Lin, Yue Zheng, Qian Li, Yufang Liu, Qingfang Xu, Yuying Li, Wei Lai
Article Number: 285
Published online on: 01 September 2026

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Generation and evaluation of multimers of anti C‑reactive protein Nb and alkaline phosphatase based on three self‑assembly peptides

Honghe Li, Chenchen Zhou, Xiaomei Zhang, Ning Ding, Qiong Wu, Junming Li, Yang Zheng, Xuejun Hu
Article Number: 284
Published online on: 28 August 2026

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New insights into diagnostic values and mechanisms of ferroptosis associated with immune infiltration in diabetic kidney disease

Ying Tan, Zihui Liu, Siyuan Song, Lingling Zhu, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan
Article Number: 283
Published online on: 28 August 2026

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Biological mechanisms underlying the effects of low‑magnitude mechanical stress in osteoporosis (Review)

Zhi Liu, Dan Han, Yanfei Wang, Hongfan Li, Xuedong Pei, Zhijing Song
Article Number: 282
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Transformation of nomifensine using ionizing radiation and exploration of its anticancer effects in MCF‑7 cells

Seong Hee Kang, Dong-Ho Bak, Byung Yeoup Chung, Hyoung-Woo Bai
Article Number: 281
Published online on: 21 August 2026

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Article

Retrospective study of infusion‑related reactions in subcutaneous daratumumab administration in Japan

Yoko Ino, Kazuhide Tanaka, Fuka Ito, Nao Yamagishi, Futa Takemura, Masahiro Yasuda, Senji Kasahara
Article Number: 280
Published online on: 20 August 2026

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Retraction Open Access

[Retracted] Combined effects of Lenvatinib and iodine‑131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress

Guoyu Wang, Juhua Zhuang, Jing Ni, Ying Ye, Saifei He, Wei Xiai
Article Number: 279
Published online on: 17 August 2026

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PDK1/AKT signaling is involved in the anti‑tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells

Haiyan Wang, Ruiming Zheng, Bujun Wang, Sumiao Hong, Hongxia Chen
Article Number: 278
Published online on: 14 August 2026

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Integrating clinical outcomes with molecular simulations to guide the selection of non‑classical EGFR‑TKIs: A comprehensive analysis and development of treatment strategies

Fang Wei, Niu Niu, Chang Li, Ge Gao, Nan Li, Yan Wang
Article Number: 277
Published online on: 14 August 2026

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Case Report Open Access

Clinicopathological analysis of neuroendocrine carcinoma discovered incidentally in hemorrhoids: A case report and literature review

Bin Huang, Haiyan Zhou, Jianping Shi, Hongsheng Liu
Article Number: 276
Published online on: 12 August 2026

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Mechanism of microRNA‑30b‑5p enhancing the response of MDA‑MB‑231 cells to cisplatin by regulating RAP1B expression

Kewei Tang, Site Bai, Yajun Tong, Songjiang Liu, Leilan Yin, Ludi Ou, Qinghua Yin, Qiang Zhou
Article Number: 275
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

Guilin Huang, Sha Hua, Tuanmin Yang, Jianbing Ma, Wenxing Yu, Xiujin Chen
Article Number: 274
Published online on: 12 August 2026

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Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model

Jing Peng, Daigui Cao, Xu Zhou, Zhiwei Liu, Xinxing Wang, Anwei Zhang, Kai Shen
Article Number: 273
Published online on: 11 August 2026

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Case Report Open Access

Rapid diagnosis of Chlamydia psittaci pneumonia with pleural effusion using multiplex PCR‑based targeted next‑generation sequencing: A case report

Yang Jin, Liqun He, Jiankun Wang, Tao Ren, Hansheng Wang, Yue Wang
Article Number: 272
Published online on: 11 August 2026

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Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study

Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin, Bang Liu, Ying He, Dai Zhou
Article Number: 271
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 270
Published online on: 10 August 2026

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RPLP0 drives diffuse large B‑cell lymphoma cell proliferation through reactive oxygen species‑dependent AKT/mTOR activation and inhibition of stress‑induced autophagy

Shanshan Wang, Xutao Yang, Rochelle Mcgowan, Belinda Hodge, Daniel Shan, Nicolas Miller, Jiahong Tang
Article Number: 269
Published online on: 07 August 2026

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Baseline neutrophil‑to‑lymphocyte ratio is not associated with chemotherapy‑induced nausea and vomiting in patients with breast cancer: A single‑center retrospective cohort study

Ruhper Cekin, Akif Dogan
Article Number: 268
Published online on: 07 August 2026

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Case Report Open Access

First case of neonatal bloodstream infection caused by Malassezia furfur in mainland China diagnosed via metagenomic next‑generation sequencing: A case report

Shanshan Gao, Lanlan Song, Qiujuan Feng, Yazhen Li, Huiqiang Liang, Ke Lei, Zheng Li, Peter Kisembo
Article Number: 267
Published online on: 06 August 2026

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Article

Comparative analysis of early and late recurrence rates in perianal fistula surgery

Ahmed Taha, Hi̇kmet Haşemi̇, Mutali̇p Ertuş, Bülent Özçeti̇n
Article Number: 266
Published online on: 06 August 2026

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Case Report

Cystic lymphangioma presenting as an ovarian mass in an adolescent: A case report and literature review

Rui Sun, Chun-Run Yang
Article Number: 265
Published online on: 05 August 2026

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Case Report

Postmenopausal osseous metaplasia of the endometrium: An uncommon histopathological entity: A case report

Emmanouela Aliki Almperi, Chrysoula Margioula Siarkou, Aristarchos Almperis, Nikoleta Dimitra Savvidou, Stamatios Petousis
Article Number: 264
Published online on: 05 August 2026

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Experimental evaluation of Curcuma Longa in docetaxel‑induced systemic toxicity: Functional hepatorenal and target organ analysis

Isabella Morais Tavares Huber, Emerson Luiz Botelho Lourenço, Salviano Tramontin Bellettini, Guilherme Donadel, João Francisco Velasquez Matumoto, Sandra Marisa Pelloso, Maria Dalva De Barros Carvalho, Stéfane Lele Rossoni, Mariana Morais Tavares Colferai, Diego Ricardo Colferai, Roberto Kenji Nakamura Cuman, Leonardo Garcia Velasquez
Article Number: 263
Published online on: 04 August 2026

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Case Report Open Access

Nasopharyngeal carcinoma with inguinal lymph node metastasis: A case report

Zhibin Lin, Shiliang Li, Donghong Yang, Tongyuan Deng, Haiwen Li, Yongcun Wang
Article Number: 262
Published online on: 04 August 2026

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Case Report

Adult‑onset focal nodular non‑exophytic nesidioblastosis mimicking insulinoma detected by endoscopic ultrasonography: A case report

Mesut Pekmez, Ümit Özçelik, Kemal Yandakçi, Alper Bilal Özkardeş
Article Number: 261
Published online on: 04 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
Article Number: 260
Published online on: 29 July 2026

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Article Open Access

Predicting lower extremity deep vein thrombosis in elderly patients with hip fracture: A machine learning model with emphasis on diabetes as a key risk factor

Qian Song, Ping'an Shi, Peng Tian, Aijun Chao, Yinguang Zhang, Qiang Dong
Article Number: 259
Published online on: 29 July 2026

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Article Open Access

Spatial specificity of Epstein‑Barr virus infection in gastric cancer: A 44‑case clinicopathological analysis

Xuming Wang, Longkuan Xu, Xiaozhen Yang, Xiaolu Yuan, Houliang Lu, Qiong Liu, Lijiang Liu
Article Number: 258
Published online on: 29 July 2026

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Article Open Access

Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

Yicheng Fu, Zhiwei Ding, Yunchuang Chang, Chunxia Wu, Sanying Wang, Genxiang Mao, Huili Su
Article Number: 257
Published online on: 29 July 2026

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Case Report

Immune‑mediated liver injury caused by checkpoint inhibitors: A case series and review of the literature

Maria Kyrkasiadou, Anastasios Kyriazoglou, Ioannis Kotsantis, Panagiota Economopoulou, George Kavourakis, Roubini Zakopoulou, Maria Anastasiou, Anastasios Pantazopoulos, Anna Boulouta, Myrto Moutafi, Niki Gavrielatou, Periklis Foukas, Menelaos Samaras, Konstantinos Palialexis, Amanda Psyrri
Article Number: 256
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Reduced expression levels of the death‑associated protein kinase and E‑cadherin are correlated with the development of esophageal squamous cell carcinoma

Jianwen Zhai, Xiaogang Yang, Yanli Zhang, Qingbin Qi, Jigang Hu, Qiaomei Wang
Article Number: 255
Published online on: 27 July 2026

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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
Article Number: 254
Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
Article Number: 253
Published online on: 24 July 2026

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Correction Open Access

[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Article Number: 252
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 32 Issue 5

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Impact Factor: 2.2

Review Open Access

Advances in drug prevention and treatment of radiation‑induced lung injury (Review)

Shuo Liu, Minting Ma, Chanjun Zhen, Yang Zhao, Yuzhi Song, Qiuying An, Zhiguo Zhou, Wenwen Bai
Article Number: 323
Published online on: 29 September 2026

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Effects of PD‑1/PD‑L1 on the malignant behavior of thyroid cancer cells through the TGF‑β/Smad signaling pathway

Xueji Wang, Jing Wang, Wei Cui, Jingxia Wang, Xueyan Zhang, Bingliang Zhang
Article Number: 322
Published online on: 29 September 2026

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Assessment of muscularis propria invasion in urothelial bladder carcinoma using continuous‑time random walk and stretched‑exponential models: Comparison with VI‑RADS and apparent diffusion coefficient

Yangying Wu, Xiaofang Zhu, Xiaolong Zhou, Canli Liu, Li Guo, Jingang Hao, Yunyun Shang
Article Number: 321
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin suppresses TNF‑α‑induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF‑κB pathway

Tian Xie, Jun Yuan, Ling Mei, Ping Li, Ruijie Pan
Article Number: 320
Published online on: 29 September 2026

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Tislelizumab‑induced psoriasis in a patient with hepatocellular carcinoma: A case report

Zhaochen Sun, Yuqi Zhou, Yeliang Mei, Yitian Chen
Article Number: 319
Published online on: 23 September 2026

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Functional heterogeneity of exosomes in hepatocellular carcinoma (Review)

Shiyan He, Xia Wu, Zhihao Wang, Xiong Zeng, Jing Lin, Jie Wang
Article Number: 318
Published online on: 23 September 2026

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Transforming growth factor β‑activated kinase 1 as a central integrator of immune‑microbiota crosstalk in colitis (Review)

Haoyu Dong, Sirui Wang, Ridong Lai, Guofeng Li
Article Number: 317
Published online on: 23 September 2026

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Integrated bioinformatics and clinical validation of oxidative stress‑associated genes in atrial fibrillation and chronic kidney disease

Jiyi Liu, Zezhou Xie, Huimin Yu, Fengzhi Sun, Ruifeng Wang, Yunbo Ba, Hao Huang, Xiaomeng Yin, Yu Wang
Article Number: 316
Published online on: 23 September 2026

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Pulmonary tuberculosis occurring during the diagnosis and treatment of sarcoidosis complicated by chylothorax: A case report 

Huai-Jie Wang, Xue Li, Wen-Ge Han, Yuan-Yuan Tang, Yan-Yan Zhang, Yu-Bing Wang, Yong Zhang, Xiao-Qi Zhang, Mei-Hua Qu
Article Number: 315
Published online on: 23 September 2026

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Retraction Open Access

[Retracted] Knockdown of lncRNA CCEPR suppresses colorectal cancer progression

Yuxia Duan, Zhixue Fang, Zeya Shi, Ling Zhang
Article Number: 314
Published online on: 22 September 2026

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Prognostic significance of the blood urea nitrogen‑to‑serum albumin ratio in patients with septic shock

Jianhua Liu, Zhengxiang Wei, Sheng Ye, Min Shao
Article Number: 313
Published online on: 21 September 2026

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Endometrial thickness and cancer risk in asymptomatic postmenopausal women: Defining evidence‑based cut‑offs by systematic review and diagnostic meta‑analysis

Yan Song, Hongying Wu, Ting Qin, Nana Li, Meng Wang
Article Number: 312
Published online on: 21 September 2026

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Case Report Open Access

Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report

Hongshan Chu, Shibo Dong, Yuan Zhang, Ruisheng Duan, Ling Li
Article Number: 311
Published online on: 21 September 2026

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Case Report

BBS10‑related Bardet‑Biedl syndrome with an atypical presentation of diabetes mellitus: A case report

Lei Zhang, Guoliang Li, Hong Chang, Yanhui Dong, Nana Sun, Rina Wu, Likun Han
Article Number: 310
Published online on: 16 September 2026

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Development of a recombinase‑aided amplification assay for rapid and sensitive detection of Pneumocystis jirovecii infection: A single‑center molecular study

Hanhan Zhu, Ben Yang, Ke Chen, Fang Xu, Meihua Qu, Yuanyuan Tang
Article Number: 309
Published online on: 16 September 2026

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Case Report

Severe steroid‑refractory immune checkpoint inhibitor‑associated pneumonitis and exploration of potential biomarkers: A case report

Yan-Jun Xue, Ai-Zhen Xu, Xin-Da Yin, Lei Wei
Article Number: 308
Published online on: 16 September 2026

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Article

Effects of ketamine and dexmedetomidine on ischemia‑ reperfusion injury in an experimental renal ischemia model

Muhammet Hanifi Erdoğan, Hakan Kardaş, Tülay Zenginkinet, Tuğba Bingöl Tanriverdi, Melek Güra Çelik
Article Number: 307
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox‑LDL‑induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway 

Tian-Jiao Lyu, Zi-Xiu Zhang, Jun Chen, Zong-Jun Liu
Article Number: 306
Published online on: 16 September 2026

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Review Open Access

Carrageenan‑induced immunothrombotic models in rodents (Review)

Xiaomu Ma, Daihan Wu, Simin Lv
Article Number: 305
Published online on: 16 September 2026

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Retraction Open Access

[Retracted] Role of peptidylarginine deiminase type 4 in gastric cancer 

Jiang Xin, Xiuqi Song
Article Number: 304
Published online on: 15 September 2026

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Article Open Access

Immune checkpoint inhibitor‑induced myocarditis with myositis and/or myasthenia gravis overlap syndrome: A case series

Qing Sun, Qing Liu, Jiabin Zheng, Yanni Lou, Huijuan Cui, Junyu Ma, Yu Wang, Dantao Peng, Weihe Zhang, Renbin Wang
Article Number: 303
Published online on: 14 September 2026

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Cardiovascular health metrics and the risk of metabolic dysfunction‑associated steatosis liver disease: A meta‑analysis

Gang Fan, Hong Zuo, Bo Liu
Article Number: 302
Published online on: 14 September 2026

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Article Open Access

Multiple relapses of cryptogenic organizing pneumonia: A case report

Sheng Xu, Beibei Li, Yanmin Li, Jian Sun, Qiang Wang
Article Number: 301
Published online on: 11 September 2026

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A diagnostic and classification model integrating cTnI, CK‑MB, MYO and NT‑proBNP for cardiovascular diseases

Huaxin Zhang, Jianan Wang, Qi Li, Tong Zhi, Xiandong Chang
Article Number: 300
Published online on: 11 September 2026

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Case Report Open Access

A rare suprasellar lesion with multifocal central nervous system involvement in clinically diagnosed von Hippel‑Lindau disease: A case report

Zekai Wu, Lei Zhang, Meng Tan, Laian Zhang
Article Number: 299
Published online on: 11 September 2026

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Case Report Open Access

Reversible osimertinib‑associated heart failure mimicking cancer recurrence in EGFR‑mutated non‑small cell lung cancer after pneumonectomy: A case report

Hirona Yokoyama, Nobuhito Hara, Rika Sasaki, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Takeshi Kawaguchi, Masatsugu Hamaji, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 298
Published online on: 11 September 2026

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Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases

Qian Wu, Daniel J. Yen
Article Number: 297
Published online on: 11 September 2026

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Retraction Open Access

[Retracted] Hsp70 inducer, 17‑allylamino‑demethoxygeldanamycin, provides neuroprotection via anti‑inflammatory effects in a rat model of traumatic brain injury

Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma
Article Number: 296
Published online on: 10 September 2026

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Case Report

Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B‑cell maturation antigen‑directed chimeric antigen receptor T‑cell immunotherapy in an advanced disease stage: A case report

Runfeng Zhang, Lili Cheng, Jinghua Liu, Lu Zhang, Junling Zhuang
Article Number: 295
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen‑activated protein kinase signaling pathways

Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Tan
Article Number: 294
Published online on: 07 September 2026

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