Journal Articles
Review
Epigenetic mechanisms and implications in tendon inflammation (Review)
Finosh G. Thankam, Chandra S. Boosani, Matthew F. Dilisio, Devendra K. Agrawal
Pages: 3-14 Published online on: 29 October 2018
Review
Proteolysis is the most fundamental property of malignancy and its inhibition may be used therapeutically (Review)
Marzena Wyganowska‑Świątkowska, Mateusz Tarnowski, Daniel Murtagh, Ewa Skrzypczak‑Jankun, Jerzy Jankun
Pages: 15-25 Published online on: 07 November 2018
Article
Anti-inflammatory and antioxidant effects of MOK, a polyherbal extract, on lipopolysaccharide‑stimulated RAW 264.7 macrophages
Ji Hye Hwang, Jun Nan Ma, Jong Hun Park, Hyo Won Jung, Yong‑Ki Park
Pages: 26-36 Published online on: 16 October 2018
Article
Bone morphogenetic protein 7 enhances the osteogenic differentiation of human dermal-derived CD105+ fibroblast cells through the Smad and MAPK pathways
Fuguo Chen, Dan Bi, Chen Cheng, Sunxiang Ma, Yang Liu, Kaixiang Cheng
Pages: 37-46 Published online on: 17 October 2018
Article
Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry
Karly‑Rai Rogers‑Broadway, Juhi Kumar, Cristina Sisu, Gurleen Wander, Emily Mazey, Jeyarooban Jeyaneethi, George Pados, Dimitris Tsolakidis, Eleftherios Klonos, Thomas Grunt, Marcia Hall, Jayanta Chatterjee, Emmanouil Karteris
Pages: 47-56 Published online on: 31 October 2018
Article
Identification of 12 novel loci that confer susceptibility to early-onset dyslipidemia
Yoshiji Yamada, Kimihiko Kato, Mitsutoshi Oguri, Hideki Horibe, Tetsuo Fujimaki, Yoshiki Yasukochi, Ichiro Takeuchi, Jun Sakuma
Pages: 57-82 Published online on: 19 October 2018
Article
A highly efficient method for isolating urinary exosomes
Liuqing He, Ding Zhu, Junpu Wang, Xiaoying Wu
Pages: 83-90 Published online on: 19 October 2018
Article
MicroRNA-98 reduces amyloid β-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer's disease mice
Fang‑Zhou Chen, Ying Zhao, Hui‑Zhao Chen
Pages: 91-102 Published online on: 24 October 2018
Article
Galectin-1 gene silencing inhibits the activation and proliferation but induces the apoptosis of hepatic stellate cells from mice with liver fibrosis
Zhi‑Jun Jiang, Qing‑Hua Shen, Hai‑Yong Chen, Zhe Yang, Ming‑Qi Shuai, Shu‑Sen Zheng
Pages: 103-116 Published online on: 23 October 2018
Article
Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition
Qing Zheng, Ming Tong, Baiqing Ou, Cuizhong Liu, Changping Hu, Yu Yang
Pages: 117-126 Published online on: 30 October 2018
Article
CircRNA-associated ceRNA network reveals ErbB and Hippo signaling pathways in hypopharyngeal cancer
Chun Feng, Yuxiao Li, Yan Lin, Xianbao Cao, Dongdong Li, Honglei Zhang, Xiaoguang He
Pages: 127-142 Published online on: 19 October 2018
Article
miR-181b-5p suppresses starvation-induced cardiomyocyte autophagy by targeting Hspa5
Liuhui Chang, Xiaoming Chai, Peiming Chen, Jianfang Cao, Hong Xie, Jiang Zhu
Pages: 143-154 Published online on: 12 November 2018
Article
Genome-wide methylation study of whole blood cells DNA in men with congenital hypopituitarism disease
Xuqian Fang, Changqiang Chen, Jialin Cai, Enfei Xiang, Jingquan Li, Peizhan Chen
Pages: 155-166 Published online on: 22 October 2018
Article
Effect of 1α, 25-dihydroxyvitamin D3 on the osteogenic differentiation of human periodontal ligament stem cells and the underlying regulatory mechanism
Yawen Ji, Panpan Zhang, Yixiao Xing, Linglu Jia, Yunpeng Zhang, Tingting Jia, Xuan Wu, Bin Zhao, Xin Xu
Pages: 167-176 Published online on: 22 October 2018
Article
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK
Yinmin Wang, Xiuxia Wang, Xianyu Zhou, Zhu Zhu, Jun Yang, Fei Liu
Pages: 177-184 Published online on: 24 October 2018
Article
Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling
Ji Eun Kim, Jun Go, Hee Seob Lee, Jin Tae Hong, Dae Youn Hwang
Pages: 185-198 Published online on: 29 October 2018
Article
N-acetylcysteine alleviates H2O2-induced damage via regulating the redox status of intracellular antioxidants in H9c2 cells
Xiehong Liu, Li Wang, Jiaodi Cai, Ke Liu, Meidong Liu, Hao Wang, Huali Zhang
Pages: 199-208 Published online on: 29 October 2018
Article
Overexpression of microRNA-183 promotes apoptosis of substantia nigra neurons via the inhibition of OSMR in a mouse model of Parkinson's disease
Jin-Xia Gao, Yu Li, Sai-Nan Wang, Xing-Chi Chen, Lu-Lu Lin, Hui Zhang
Pages: 209-220 Published online on: 07 November 2018
Article
‘Governor vessel-unblocking and mind-regulating’ acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion
Xuan Su, Zuqiang Wu, Fangyong Mai, Zhiyong Fan, Shujia Du, Hong Qian, Jingwen Zhu
Pages: 221-232 Published online on: 06 November 2018
Article
Application of metabolomics part II: Focus on fatty acids and their metabolites in healthy adults
Dimitrios Tsoukalas, Athanasios K. Alegakis, Persefoni Fragkiadaki, Evangelos Papakonstantinou, Gerasimos Tsilimidos, Franco Geraci, Evangelia Sarandi, Dragana Nikitovic, Demetrios A. Spandidos, Aristides Tsatsakis
Pages: 233-242 Published online on: 14 November 2018
Article
Next generation sequencing reveals novel alterations in B-cell heavy chain receptor repertoires associated with acute-on-chronic liver failure
Qiang Yan, Lei Wang, Liusheng Lai, Song Liu, Huaizhou Chen, Jiaxing Zhang, Yong Dai, Weiguo Sui
Pages: 243-255 Published online on: 22 October 2018
Article
Downregulation of miR-145-5p in cancer cells and their derived exosomes may contribute to the development of ovarian cancer by targeting CT
Wenzhao Hang, Yiwen Feng, Zhenyu Sang, Ye Yang, Yaping Zhu, Qian Huang, Xiaowei Xi
Pages: 256-266 Published online on: 25 October 2018
Article
MicroRNA-421-targeted PDCD4 regulates breast cancer cell proliferation
Yiwei Wang, Zipeng Liu, Jian Shen
Pages: 267-275 Published online on: 15 October 2018
Article
Bioinformatics-based study to detect chemical compounds that show potential as treatments for pulmonary thromboembolism
Keyu Sun, Zichen Xie, Jiqin Wang, Meirong Ling, Yanyan Li, Chao Qiu
Pages: 276-284 Published online on: 12 November 2018
Article
The short-term effect of histone deacetylase inhibitors, chidamide and valproic acid, on the NF‑κB pathway in multiple myeloma cells
Zhaoyun Liu, Qian Jing, Yangyang Wang, Yanqi Li, Fu Mi, Chenhuan Xiang, Rong Fu
Pages: 285-293 Published online on: 29 October 2018
Article
Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway
Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Miao
Pages: 294-304 Published online on: 15 October 2018
Article
High-pressure carbon dioxide pneumoperitoneum induces oxidative stress and mitochondria-associated apoptotic pathway in rabbit kidneys with severe hydronephrosis
Sheng Zhao, Wei Li, Fan Cheng, Ting Rao, Weimin Yu, Yuan Ruan, Run Yuan, Xiaobing Yao, Jinzhuo Ning
Pages: 305-315 Published online on: 08 November 2018
Article
Mitochondria-targeted antioxidant therapy for an animal model of PCOS-IR
Yu Ding, Zhaochang Jiang, Bohou Xia, Lizong Zhang, Caijuan Zhang, Jianhang Leng
Pages: 316-324 Published online on: 05 November 2018
Article
Crosstalk between mitogen-activated protein kinase inhibitors and transforming growth factor-β signaling results in variable activation of human dermal fibroblasts
David M. Dolivo, Sara A. Larson, Tanja Dominko
Pages: 325-335 Published online on: 23 October 2018
Article
Alterations of autophagy in knee cartilage by treatment with treadmill exercise in a rat osteoarthritis model
Xiaoning Zhang, Yue Yang, Xin Li, He Zhang, Yi Gang, Lunhao Bai
Pages: 336-344 Published online on: 23 October 2018
Article
lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression
Xiang Zhu, Hongqi Li, Yuanbo Wu, Jian Zhou, Guangwei Yang, Weidong Wang
Pages: 345-357 Published online on: 05 November 2018
Article
Exosome-mediated microRNA-138 and vascular endothelial growth factor in endometriosis through inflammation and apoptosis via the nuclear factor-κB signaling pathway
Aifeng Zhang, Guoyun Wang, Lihua Jia, Tao Su, Lili Zhang
Pages: 358-370 Published online on: 06 November 2018
Article
SENP1 has an important role in lung development and influences the differentiation of alveolar type 2 cells
Xue‑Qing Wan, Jia‑Yu Cai, Yue Zhu, Qiu‑Xia Wang, Hai‑Tao Zhu, Hui‑Min Ju, Hong‑Yan Lu
Pages: 371-381 Published online on: 29 October 2018
Article
Guanine and nucleotide binding protein 3 promotes odonto/osteogenic differentiation of apical papilla stem cells via JNK and ERK signaling pathways
Yang Zhang, Lichan Yuan, Li Meng, Mengru Fang, Shuyu Guo, Dongyue Wang, Junqing Ma, Lin Wang
Pages: 382-392 Published online on: 07 November 2018
Article
Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague‑Dawley rats and exhibits protection from NF-κB-induced inflammation in WI38 fibroblast cells
Suchismita Raha, Seong Min Kim, Ho Jeong Lee, Sang Joon Lee, Jeong Doo Heo, Venu Venkatarame Gowda Saralamma, Sang Eun Ha, Eun Hee Kim, Sung Phil Mun, Gon Sup Kim
Pages: 393-403 Published online on: 31 October 2018
Article
Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis
Chao Ci, Biao Tang, Dalun Lyu, Wenbei Liu, Di Qiang, Xiang Ji, Xiamin Qiu, Lei Chen, Wei Ding
Pages: 404-412 Published online on: 07 November 2018
Article
Hyperforin improves post-stroke social isolation‑induced exaggeration of PSD and PSA via TGF-β
Yujing Zhang, Peiyun Yu, Hong Liu, Hua Yao, Shanglong Yao, Shi‑Ying Yuan, Jian‑Cheng Zhang
Pages: 413-425 Published online on: 02 November 2018
Article
Administration of plasmacytoid dendritic cell-stimulative lactic acid bacteria is effective against dengue virus infection in mice
Hiroaki Suzuki, Ryohei Tsuji, Miho Sugamata, Naoki Yamamoto, Norio Yamamoto, Osamu Kanauchi
Pages: 426-434 Published online on: 24 October 2018
Article
Amyloid β and tau are involved in sleep disorder in Alzheimer's disease by orexin A and adenosine A(1) receptor
Zhenhua Liu, Fumin Wang, Minglu Tang, Yongjun Zhao, Xiaoting Wang
Pages: 435-442 Published online on: 16 October 2018
Article
Neuroprotective effects of midazolam on focal cerebral ischemia in rats through anti‑apoptotic mechanisms
Hang Yu, Xiaozhi Wang, Fuxin Kang, Zhile Chen, Yunxia Meng, Mingming Dai
Pages: 443-451 Published online on: 05 November 2018
Article
Propofol attenuates inflammatory damage on neurons following cerebral infarction by inhibiting excessive activation of microglia
Hang Yu, Xiaozhi Wang, Fuxin Kang, Zhile Chen, Yunxia Meng, Mingming Dai
Pages: 452-460 Published online on: 05 November 2018
Article
Quercetin‑3‑O‑α‑L‑rhamnopyranoside derived from the leaves of Lindera aggregata (Sims) Kosterm. evokes the autophagy‑induced nuclear factor erythroid 2‑related factor 2 antioxidant pathway in human umbilical vein endothelial cells
Haote Han, Bo Xu, Awais Amin, Hongliang Li, Xiuying Yu, Minghua Gong, Lin Zhang
Pages: 461-474 Published online on: 05 November 2018
Article
COX-2 induces apoptosis-resistance in hepatocellular carcinoma cells via the HIF-1α/PKM2 pathway
Qin Wang, Donghui Lu, Lulu Fan, Yuhuan Li, Yu Liu, Hanqing Yu, Hua Wang, Jiatao Liu, Guoping Sun
Pages: 475-488 Published online on: 16 October 2018
Article
Muscat Bailey A grape stalk extract ameliorates high-fat diet‑induced obesity by downregulating PPARγ and C/EPBα in mice
Bo‑Mi Kim, Byoung Ok Cho, Seon Il Jang
Pages: 489-500 Published online on: 24 October 2018
Article
Effect of tetramethylpyrazine and hyperlipidemia on hepcidin homeostasis in mice
Miao Zhang, Ming‑Yue Sun, Chun‑Yu Guo, Jing‑Shang Wang, Feng‑Qin Xu, Hui‑Jun Yin
Pages: 501-506 Published online on: 01 November 2018
Article
Suppression of cyclooxygenase 2 increases chemosensitivity to sesamin through the Akt‑PI3K signaling pathway in lung cancer cells
Qing Fang, Yuyin Zhu, Qilai Wang, Meijun Song, Guosheng Gao, Zhiming Zhou
Pages: 507-516 Published online on: 18 October 2018
Article
miR-186 reverses cisplatin resistance and inhibits the formation of the glioblastoma-initiating cell phenotype by degrading Yin Yang 1 in glioblastoma
Jian Li, Jie Song, Feng Guo
Pages: 517-524 Published online on: 18 October 2018
Article
MicroRNA‑222‑3p promotes tumor cell migration and invasion and inhibits apoptosis, and is correlated with an unfavorable prognosis of patients with renal cell carcinoma
Liwen Zhao, Jing Quan, Zuwei Li, Xiang Pan, Jingyao Wang, Jinling Xu, Weijie Xu, Xin Guan, Hang Li, Shangqi Yang, Yaoting Gui, Yun Chen, Yongqing Lai
Pages: 525-534 Published online on: 15 October 2018
Article
Fibroblast growth factor-23 may serve as a novel biomarker for renal osteodystrophy progression
Si Yan Liu, Dong Dong Zhang, Yang Fang Wu, Huang Huang Luo, Guang Mei Jiang, Yao Xu, Yue Wu, Xun Xia, Wei Wei, Bo Hu, Peng Hu
Pages: 535-546 Published online on: 15 October 2018
Article
Knockdown of long non-coding RNA metastasis associated lung adenocarcinoma transcript 1 inhibits the proliferation and migration of bladder cancer cells by modulating the microRNA-34a/cyclin D1 axis
Ye Liu, Saiyue Gao, Qingyan Du, Qingsong Zhao
Pages: 547-556 Published online on: 29 October 2018
Article
CZ2HF mitigates β-amyloid 25-35 fragment-induced learning and memory impairment through inhibition of neuroinflammation and apoptosis in rats
Lingrong Zeng, Jianmei Gao, Yuanyuan Deng, Jingshan Shi, Qihai Gong
Pages: 557-566 Published online on: 24 October 2018
Article
Deletion of FOXL2 by CRISPR promotes cell cycle G0/G1 restriction in KGN cells
Bin Tang, Yujie Zhang, Wei Zhang, Yuqing Zhu, Shaopeng Yuan
Pages: 567-574 Published online on: 24 October 2018
Article
Ligustrazine inhibits platelet activation via suppression of the Akt pathway
Li Li, Hongwei Chen, Aling Shen, Qiongyu Li, Youqin Chen, Jianfeng Chu, Liya Liu, Jun Peng, Keji Chen
Pages: 575-582 Published online on: 01 November 2018
Article
Bone morphogenetic protein 2 alleviated intervertebral disc degeneration through mediating the degradation of ECM and apoptosis of nucleus pulposus cells via the PI3K/Akt pathway
Yanlin Tan, Xingwang Yao, Zhehao Dai, Yunhua Wang, Guohua Lv
Pages: 583-592 Published online on: 02 November 2018
Article
In vitro enhancement and functional characterization of neurite outgrowth by undifferentiated adipose-derived stem cells
Vesna Bucan, Malte Fliess, Reinhild Schnabel, Claas‑Tido Peck, Desiree Vaslaitis, Angela Fülbier, Kerstin Reimers, Sarah Strauss, Peter M. Vogt, Christine Radtke
Pages: 593-602 Published online on: 06 November 2018
Article
Anti-obesity effects of Diospyros lotus leaf extract in mice with high-fat diet-induced obesity
Bo‑Mi Kim, Byoung Ok Cho, Seon Il Jang
Pages: 603-613 Published online on: 18 October 2018
Article
Suppressing serum response factor inhibits invasion in cervical cancer cell lines via regulating Egr‑1 and epithelial-mesenchymal transition
Liya Ma, Ying Yu, Xiaohui Qu
Pages: 614-620 Published online on: 24 October 2018
Article
C1QTNF6 is overexpressed in gastric carcinoma and contributes to the proliferation and migration of gastric carcinoma cells
Hai‑Xia Qu, Lin Cui, Xin‑Ying Meng, Zhi‑Jie Wang, Yan‑Xin Cui, Yun‑Peng Yu, Dong Wang, Xiang‑Jun Jiang
Pages: 621-629 Published online on: 06 November 2018
Article
