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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2021 Volume 22 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

CTBP1 strengthens the cisplatin resistance of gastric cancer cells by upregulating RAD51 expression

Yuluo Wu, Haiyang Zhao
Article Number: 810
Published online on: 27 September 2021

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Review Open Access

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives (Review)

Leonel Pekarek, Oscar Fraile‑Μartinez, Cielo Garcia‑Montero, Miguel A. Alvarez‑Mon, Julio Acero, Lidia Ruiz‑Llorente, Natalio García‑Honduvilla, Agustin Albillos, Julia Buján, Melchor Alvarez‑Mon, Luis G. Guijarro, Miguel A. Ortega
Article Number: 809
Published online on: 27 September 2021

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Article Open Access

MicroRNA‑135a expression is upregulated in hepatocellular carcinoma and targets long non‑coding RNA TONSL‑AS1 to suppress cell proliferation

Xuesong Deng, Jun Cheng, Naiyang Zhan, Jianwei Chen, Yongqiang Zhan, Yong Ni, Caixian Liao
Article Number: 808
Published online on: 24 September 2021

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Article Open Access

Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current

María Luisa Hernández‑Bule, María Antonia Martínez, María Ángeles Trillo, Lidia Martínez, Elena Toledano‑Macías, Alejandro Úbeda
Article Number: 807
Published online on: 23 September 2021

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Review Open Access

Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review)

Norlia Abdullah, Norazlina Mohamed
Article Number: 806
Published online on: 23 September 2021

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Article Open Access

miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression

Venhar Gurbuz, Sinan Sozen, Cenk Y. Bilen, Ece Konac
Article Number: 805
Published online on: 23 September 2021

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Article Open Access

β2‑adrenergic receptor expression and the effects of norepinephrine and propranolol on various head and neck cancer subtypes

Soon Young Kwon, Kyung Ju Chun, Hong Kwon Kil, Narae Jung, Hyun-Ah Shin, Jeon Yeob Jang, Hyo Geun Choi, Kyoung-Ho Oh, Min-Su Kim
Article Number: 804
Published online on: 23 September 2021

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Article Open Access

Analysis of expression profiles and prognostic value of COP9 signalosome subunits for patients with head and neck squamous cell carcinoma

Hao Zhou, Wei Sun, Jiaruan Zou
Article Number: 803
Published online on: 23 September 2021

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Article Open Access

Long non‑coding RNA NEAT1 promotes the malignancy of laryngeal squamous cell carcinoma by regulating the microRNA‑204‑5p/SEMA4B axis Retraction in /10.3892/ol.2023.14148

Ling Han, Chaopan Zheng, Shihai Wu
Article Number: 802
Published online on: 23 September 2021

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Article Open Access

Long non‑coding RNA XIST accelerates hepatic carcinoma progression by targeting the microRNA‑320a/PIK3CA axis

Lina Yang, Fangliang Xie, Weidong Xu, Tonglei Xu, Yuan Ni, Xiao Tao, Yu Zang, Juan Jin
Article Number: 801
Published online on: 23 September 2021

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Retraction Open Access

[Retracted] Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue
Article Number: 800
Published online on: 22 September 2021

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Article Open Access

Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation Expression of Concern in /10.3892/ol.2026.15802

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 799
Published online on: 20 September 2021

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Article Open Access

Knockdown of lncRNA NUTM2A‑AS1 inhibits lung adenocarcinoma cell viability by regulating the miR‑590‑5p/METTL3 axis Retraction in /10.3892/ol.2025.15424

Jie Wang, Jingyun Zha, Xiaolin Wang
Article Number: 798
Published online on: 20 September 2021

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Article Open Access

Targeting Mps1 in combination with paclitaxel inhibits osteosarcoma progression by modulating spindle assembly checkpoint and Akt/mTOR signaling

Lu Lu, Yuhai Wang, Jian Chen, Ye Li, Qingyang Liang, Feng Li, Chuanchuan Zhen, Kegong Xie
Article Number: 797
Published online on: 17 September 2021

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Article

lncRNA CYTOR promotes cell proliferation and tumor growth via miR‑125b/SEMA4C axis in hepatocellular carcinoma

Qing Tian, Xiaodong Yan, Long Yang, Zirong Liu, Zheyue Yuan, Yamin Zhang
Article Number: 796
Published online on: 17 September 2021

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Article Open Access

circ‑ACACA promotes proliferation, invasion, migration and glycolysis of cervical cancer cells by targeting the miR‑582‑5p/ERO1A signaling axis

Dandan Huang, Cuimei Li
Article Number: 795
Published online on: 17 September 2021

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Article Open Access

A novel long non‑coding RNA TTN‑AS1/microRNA‑589‑5p/FOXP1 positive feedback loop increases the proliferation, migration and invasion of pancreatic cancer cell lines

Jing Zhao, Fang Wu, Jun Yang
Article Number: 794
Published online on: 17 September 2021

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Article Open Access

GHSR methylation‑dependent expression of a variant ligand and receptor of the ghrelin system induces thymoma tumorigenesis

Bilguun Tegshee, Kazuya Kondo, Shiho Soejima, Kyoka Muguruma, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku
Article Number: 793
Published online on: 17 September 2021

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Article

Four plasma miRNAs act as biomarkers for diagnosis and prognosis of non‑small cell lung cancer

He-Guo Jiang, Chun-Hua Dai, Ya-Ping Xu, Qian Jiang, Xian-Bin Xia, Yang Shu, Jian Li
Article Number: 792
Published online on: 17 September 2021

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Article Open Access

HMBS is the most suitable reference gene for RT‑qPCR in human HCC tissues and blood samples

Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Juan A Son, Donglim You, Jung Hwan Yoon, Hyoung Jung Cho, Soon Sun Kim, Jae Yeon Cheong, Jung Woo Eun
Article Number: 791
Published online on: 17 September 2021

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Article Open Access

Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity

Nanaka Morita, Masato Hoshi, Takeshi Hara, Soranobu Ninomiya, Taisuke Enoki, Misao Yoneda, Hisashi Tsurumi, Kuniaki Saito
Article Number: 790
Published online on: 17 September 2021

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Article Open Access

Microarray analysis of differentially expressed long non‑coding RNAs in daidzein‑treated lung cancer cells

Laifang Li, Jun Liu, Xiaobo Wang, Xiaowei Xiong, Shaoxin Huang, Xin Wang
Article Number: 789
Published online on: 17 September 2021

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Article Open Access

Efficacy and safety of humanized CD19 CAR‑T as a salvage therapy for recurrent CNSL of B‑ALL following murine CD19 CAR‑T cell therapy

Xin Li, Mei-Jing Liu, Nan Mou, Zhen-Xing Yang, Jia  Wang, Juan Mu, Hai-Bo Zhu, Qi Deng
Article Number: 788
Published online on: 16 September 2021

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Review Open Access

Immune checkpoints and immunotherapy in non‑small cell lung cancer: Novel study progression, challenges and solutions (Review)

Lin-Rui Ma, Jia-Xin Li, Ling Tang, Run-Ze Li, Jia-Shun Yang, Ao Sun, Elaine Lai‑Han Leung, Pei-Yu Yan
Article Number: 787
Published online on: 14 September 2021

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Article Open Access

Protein overexpression of toll‑like receptor 4 and myeloid differentiation factor 88 in oral squamous cell carcinoma and clinical significance

Lili Li, Zhuoqian Zhou, Khangvu Mai, Ping Li, Zongqi Wang, Yaxi Wang, Yang Cao, Xuemeng Ma, Tingting Zhang, Daiyou Wang
Article Number: 786
Published online on: 14 September 2021

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Review Open Access

An overview of mesenchymal stem cells and their potential therapeutic benefits in cancer therapy (Review)

Shern Kwok Lim, Boon Yin Khoo
Article Number: 785
Published online on: 14 September 2021

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Article Open Access

Maternally expressed 3 inhibits the biological activity of oral squamous cell carcinoma SCC25 and CAL27 cell lines

Wenjing Wang, Huanju Li, Yongle Qiu, Kunshan Li, Yueting Lu, Qianlan Deng, Tiejun Liu
Article Number: 784
Published online on: 13 September 2021

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Article Open Access

Effect of neutropenia on survival outcomes of patients with metastatic colorectal cancer receiving trifluridine/tipiracil plus bevacizumab

Daisaku Kamiimabeppu, Hiroki Osumi, Eiji Shinozaki, Akira Ooki, Takeru Wakatsuki, Koichiro Yoshino, Taro Sato, Izuma Nakayama, Mariko Ogura, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi
Article Number: 783
Published online on: 13 September 2021

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Article Open Access

NDRG4 sensitizes CRC cells to 5‑FU by upregulating DDIT3 expression Corrigendum in /10.3892/ol.2022.13321

Ruikai Li, Chenxiang He, Liangliang Shen, Shuai Wang, Yao Shen, Fan Feng, Jian Zhang, Jianyong Zheng
Article Number: 782
Published online on: 13 September 2021

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Article Open Access

Ferroptosis is involved in the anti‑tumor effect of lycorine in renal cell carcinoma cells

Yang Du, Hong-Chao Zhao, Heng-Cheng Zhu, Yao Jin, Lei Wang
Article Number: 781
Published online on: 13 September 2021

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Article

Identification of soluble tissue‑derived biomarkers from human thyroid tissue explants maintained on a microfluidic device

Andrew Riley, Heidi Jones, James England, Dmitriy Kuvshinov, Victoria Green, John Greenman
Article Number: 780
Published online on: 13 September 2021

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Article Open Access

Repurposing non‑invasive prenatal testing data: Population study of single nucleotide variants associated with colorectal cancer and Lynch syndrome

Natalia Forgacova, Juraj Gazdarica, Jaroslav Budis, Jan Radvanszky, Tomas Szemes
Article Number: 779
Published online on: 13 September 2021

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Article Open Access

Dynamic contrast‑enhanced MRI as a predictor of programmed death ligand‑1 expression in patients with oral squamous cell carcinoma

Nouha Tekiki, Mariko Fujita, Tatsuo Okui, Hotaka Kawai, May Wathone Oo, Toshiyuki Kawazu, Miki Hisatomi, Shunsuke Okada, Yohei Takeshita, Majd Barham, Hitoshi Nagatsuka, Yoshinobu Yanagi, Jun-Ichi Asaumi
Article Number: 778
Published online on: 13 September 2021

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Article Open Access

Construction and validation of nomograms for non‑metastatic Ewing sarcoma: A prognostic factor analysis based on the SEER database

Runzhi Huang, Dong Han, Chengcheng Shi, Penghui Yan, Peng Hu, Xiaolong Zhu, Huabin Yin, Tong Meng, Zongqiang Huang
Article Number: 777
Published online on: 13 September 2021

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Article Open Access

PET/MRI is useful for early detection of pelvic insufficiency fractures after radiotherapy for cervical cancer

Maho Azumi, Masuyo Matsumoto, Kaho Suzuki, Ryohei Sasaki, Yoshiko Ueno, Munenobu Nogami, Yoshito Terai
Article Number: 776
Published online on: 10 September 2021

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Review Open Access

Research progress concerning m6A methylation and cancer (Review)

Yang Zhou, Jie Yang, Zheng Tian, Jing Zeng, Weigan Shen
Article Number: 775
Published online on: 10 September 2021

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Article Open Access

Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma

Amos C. Hung, Yen-Yun Wang, Kun-Tsung Lee, Hung-Hsing Chiang, Yuk-Kwan Chen, Je-Kang Du, Chun-Ming Chen, Michael Yuanchien Chen, Kwei-Jing Chen, Stephen Chu-Sung Hu, Shyng-Shiou F. Yuan
Article Number: 774
Published online on: 10 September 2021

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Article Open Access

Long non‑coding RNA TMCC1‑AS1 predicts poor prognosis and accelerates epithelial‑mesenchymal transition in liver cancer Retraction in /10.3892/ol.2024.14785

Cheng Chen, Na Su, Guiying Li, Yanfeng Shen, Xiaoting Duan
Article Number: 773
Published online on: 09 September 2021

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Article Open Access

Long non‑coding RNA UCA1 enhances cervical cancer cell proliferation and invasion by regulating microRNA‑299‑3p expression

Ming An, Xuefeng Xing, Tonghua Chen
Article Number: 772
Published online on: 09 September 2021

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Article Open Access

Oncotype DX 21‑gene test has a low recurrence score in both pure and mixed mucinous breast carcinoma

Rui Chen, Yun Wang, Taolang Li, Junyuan Lv, Guoli Feng, Na Tan, Jinjing Wang, Xiaoming Cheng
Article Number: 771
Published online on: 09 September 2021

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Review Open Access

Cross‑link between ferroptosis and nasopharyngeal carcinoma: New approach to radiotherapy sensitization (Review)

Hai-Long Li, Nian-Hua Deng, Jia-Xin Xiao, Xiu-Sheng He
Article Number: 770
Published online on: 09 September 2021

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Article Open Access

Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling

Wei Hu, Mingxu Li, Junyi Wu, Hong Chen, Ting  Zhao, Chunjie Zhang, Zhong Wang
Article Number: 769
Published online on: 08 September 2021

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Article Open Access

Itraconazole improves survival outcomes in patients with colon cancer by inducing autophagic cell death and inhibiting transketolase expression

Pei-Wen Shen, Yu-Mei Chou, Chia-Ling Li, En-Chih Liao, Hung-Sen Huang, Chun-Hao Yin, Chien-Liang Chen, Sheng-Jie Yu
Article Number: 768
Published online on: 08 September 2021

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Article Open Access

Propofol induces the ferroptosis of colorectal cancer cells by downregulating STAT3 expression

Xining Zhao, Fei Chen
Article Number: 767
Published online on: 08 September 2021

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Article Open Access

Nanoscale Au@SiO2‑drug/VEGF as an in vivo probe for osteosarcoma diagnosis and therapy

Tiangui Chen, Tianbo Li, Jiangning Wang
Article Number: 766
Published online on: 08 September 2021

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Article Open Access

LAPTM4B promotes the progression of bladder cancer by stimulating cell proliferation and invasion

Yanhua Yin, Yanyan Fan, Gang Yu, Ying Du
Article Number: 765
Published online on: 08 September 2021

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Article Open Access

Double‑stranded RNA‑specific adenosine deaminase‑knockdown inhibits the proliferation and induces apoptosis of DU145 and PC3 cells by promoting the phosphorylation of H2A.X variant histone

Xiezhao Li, Rui Zhu, Yaoji Yuan, Zhiduan Cai, Siyang Liang, Jun Bian, Guibin Xu
Article Number: 764
Published online on: 08 September 2021

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Article Open Access

MicroRNA‑545‑5p regulates apoptosis, migration and invasion of osteosarcoma by targeting dimethyladenosine transferase 1

Hai-Zhen Zhou, Bo Chen, Xiao-Ju Li, Juan-Juan Du, Nan Zhang, Yu-Xiong Shao, Kun Zhang, Zhi-Chao Tong
Article Number: 763
Published online on: 06 September 2021

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Article Open Access

circRNA circ_POLA2 increases microRNA‑31 methylation to promote endometrial cancer cell proliferation

Xia Fang, Jinhua Wang, Lingying Chen, Xiaochun Zhang
Article Number: 762
Published online on: 06 September 2021

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Article Open Access

Role of NELF‑B in supporting epithelial‑mesenchymal transition and cell proliferation during hepatocellular carcinoma progression

Mennatallah Hani Ghouraba, Razan Jamil Masad, Eric Zadok Mpingirika, Omnia Mahmoud Abdelraheem, Rached Zeghlache, Aya M Alserw, Asma Amleh
Article Number: 761
Published online on: 06 September 2021

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Article Open Access

Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma

Patcharaporn Boottanun, Yoshinori Ino, Kazuaki Shimada, Nobuyoshi Hiraoka, Kiyohiko Angata, Hisashi Narimatsu
Article Number: 760
Published online on: 03 September 2021

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Article

Antiproliferative effect of GTS‑21 in glioblastoma cells

Malgorzata A. Kolodziej, Hanna Gött, Benjamin Kopischke, Michael K.F. Bender, Markus A. Weigand, Pietro Di Fazio, Frank P. Schwarm, Florian Uhle
Article Number: 759
Published online on: 02 September 2021

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Review Open Access

The mechanism of non‑coding RNAs in medulloblastoma (Review)

Ying-Nan Zhao, Kun Li, Xing-Sheng Han, Ya-Wen Pan
Article Number: 758
Published online on: 02 September 2021

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Article Open Access

Knockdown of lncRNA C5orf66‑AS1 inhibits osteosarcoma cell proliferation and invasion via miR‑149‑5p upregulation Corrigendum in /10.3892/ol.2025.15000

Hui Zhang, Jie Song
Article Number: 757
Published online on: 02 September 2021

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Article Open Access

UCHL3 plays an important role in the occurrence and development of melanoma

Runzhi He, Yajing Zhou, Jianmin Liu, Xiaochong Zhang, Xiaoling Zhao, Lihui An, Zihan Li, Fang Cheng
Article Number: 756
Published online on: 01 September 2021

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Article Open Access

T‑box 2 expression is a useful indicator of the response to neoadjuvant chemotherapy for patients with locally advanced uterine cervical squamous cell carcinoma

Yuta Inoue, Takeshi Fukuda, Shigenori Nanno, Yuichiro Awazu, Masahiro Shimomura, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 755
Published online on: 31 August 2021

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Article Open Access

EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro Corrigendum in /10.3892/ol.2026.15642

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 754
Published online on: 31 August 2021

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Article Open Access

Screening and identification of differentially expressed microRNAs in diffuse large B‑cell lymphoma based on microRNA microarray

Hai-Xia Gao, Si-Jing Li, Meng-Bo Wang, Shu-Fang Yan, Wen-Li Cui, Zhi-Ping Ma, Jing Xue, Wei Sang, Wei Zhang, Xin-Xia Li
Article Number: 753
Published online on: 27 August 2021

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Article Open Access

MicroRNA‑382‑5p inhibits osteosarcoma development and progression by negatively regulating VEZF1 expression

Hui Wu, Yu-Xi Luo, Wen Hu, Mao-Lin Zhao, Jun Bie, Mi Yang, Rongqiang Pan, Nan-Xiang Huang, Gang Feng, Kang Liu, Guiqin Song
Article Number: 752
Published online on: 27 August 2021

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Expression of oncogenic long noncoding RNA PSMG3‑antisense 1 in lung squamous cell carcinoma

E Jin, Chao Huang, Lei Zhang, Shiyi Chen, Xiaochen Zhao, Zheng Ren, Hong Fu
Article Number: 751
Published online on: 27 August 2021

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Progress on the study of the anticancer effects of artesunate (Review)

Xiulan Yang, Yudong Zheng, Lian Liu, Jiangrong Huang, Fei Wang, Jie Zhang
Article Number: 750
Published online on: 27 August 2021

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Anti‑Axl monoclonal antibodies attenuate the migration of MDA‑MB‑231 breast cancer cells

Hong Chang, Ran An, Xinying Li, Xiaoling Lang, Jiannan Feng, Ming Lv
Article Number: 749
Published online on: 27 August 2021

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Role of Toll‑like receptors in natural killer cell function in acute lymphoblastic leukemia (Review)

Janet Gallardo‑Zapata, Carmen Maldonado‑Bernal
Article Number: 748
Published online on: 24 August 2021

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CRMP5 regulates cell proliferation and development of colorectal cancer via MAPK‑dependent signaling

Fanghua Qiu, Lin Yu, Daoli Liu, Yujin Wu, Feng Qiu
Article Number: 747
Published online on: 24 August 2021

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A study on the clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography combined with serum squamous cell carcinoma antigen in diagnosing recurrence/metastases in patients with early metaphase cervical cancer

Chi Qi, Shasha He, Liang Cai, Li Zhang, Haoyuan Ding, Yue Chen
Article Number: 746
Published online on: 24 August 2021

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Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine, but not azacitidine, in acute myeloid leukemia with RAS mutations

Jihyun Park, Hyejoo Park, Ja Min Byun, Junshik Hong, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon
Article Number: 745
Published online on: 20 August 2021

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October-2026 Volume 32 Issue 4

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Article Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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