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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2021 Volume 22 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

CTBP1 strengthens the cisplatin resistance of gastric cancer cells by upregulating RAD51 expression

Yuluo Wu, Haiyang Zhao
Article Number: 810
Published online on: 27 September 2021

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Review Open Access

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives (Review)

Leonel Pekarek, Oscar Fraile‑Μartinez, Cielo Garcia‑Montero, Miguel A. Alvarez‑Mon, Julio Acero, Lidia Ruiz‑Llorente, Natalio García‑Honduvilla, Agustin Albillos, Julia Buján, Melchor Alvarez‑Mon, Luis G. Guijarro, Miguel A. Ortega
Article Number: 809
Published online on: 27 September 2021

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Article Open Access

MicroRNA‑135a expression is upregulated in hepatocellular carcinoma and targets long non‑coding RNA TONSL‑AS1 to suppress cell proliferation

Xuesong Deng, Jun Cheng, Naiyang Zhan, Jianwei Chen, Yongqiang Zhan, Yong Ni, Caixian Liao
Article Number: 808
Published online on: 24 September 2021

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Article Open Access

Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current

María Luisa Hernández‑Bule, María Antonia Martínez, María Ángeles Trillo, Lidia Martínez, Elena Toledano‑Macías, Alejandro Úbeda
Article Number: 807
Published online on: 23 September 2021

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Review Open Access

Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review)

Norlia Abdullah, Norazlina Mohamed
Article Number: 806
Published online on: 23 September 2021

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Article Open Access

miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression

Venhar Gurbuz, Sinan Sozen, Cenk Y. Bilen, Ece Konac
Article Number: 805
Published online on: 23 September 2021

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Article Open Access

β2‑adrenergic receptor expression and the effects of norepinephrine and propranolol on various head and neck cancer subtypes

Soon Young Kwon, Kyung Ju Chun, Hong Kwon Kil, Narae Jung, Hyun-Ah Shin, Jeon Yeob Jang, Hyo Geun Choi, Kyoung-Ho Oh, Min-Su Kim
Article Number: 804
Published online on: 23 September 2021

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Article Open Access

Analysis of expression profiles and prognostic value of COP9 signalosome subunits for patients with head and neck squamous cell carcinoma

Hao Zhou, Wei Sun, Jiaruan Zou
Article Number: 803
Published online on: 23 September 2021

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Article Open Access

Long non‑coding RNA NEAT1 promotes the malignancy of laryngeal squamous cell carcinoma by regulating the microRNA‑204‑5p/SEMA4B axis Retraction in /10.3892/ol.2023.14148

Ling Han, Chaopan Zheng, Shihai Wu
Article Number: 802
Published online on: 23 September 2021

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Article Open Access

Long non‑coding RNA XIST accelerates hepatic carcinoma progression by targeting the microRNA‑320a/PIK3CA axis

Lina Yang, Fangliang Xie, Weidong Xu, Tonglei Xu, Yuan Ni, Xiao Tao, Yu Zang, Juan Jin
Article Number: 801
Published online on: 23 September 2021

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Retraction Open Access

[Retracted] Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue
Article Number: 800
Published online on: 22 September 2021

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Article Open Access

Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 799
Published online on: 20 September 2021

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Article Open Access

Knockdown of lncRNA NUTM2A‑AS1 inhibits lung adenocarcinoma cell viability by regulating the miR‑590‑5p/METTL3 axis

Jie Wang, Jingyun Zha, Xiaolin Wang
Article Number: 798
Published online on: 20 September 2021

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Article Open Access

Targeting Mps1 in combination with paclitaxel inhibits osteosarcoma progression by modulating spindle assembly checkpoint and Akt/mTOR signaling

Lu Lu, Yuhai Wang, Jian Chen, Ye Li, Qingyang Liang, Feng Li, Chuanchuan Zhen, Kegong Xie
Article Number: 797
Published online on: 17 September 2021

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Article

lncRNA CYTOR promotes cell proliferation and tumor growth via miR‑125b/SEMA4C axis in hepatocellular carcinoma

Qing Tian, Xiaodong Yan, Long Yang, Zirong Liu, Zheyue Yuan, Yamin Zhang
Article Number: 796
Published online on: 17 September 2021

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Article Open Access

circ‑ACACA promotes proliferation, invasion, migration and glycolysis of cervical cancer cells by targeting the miR‑582‑5p/ERO1A signaling axis

Dandan Huang, Cuimei Li
Article Number: 795
Published online on: 17 September 2021

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Article Open Access

A novel long non‑coding RNA TTN‑AS1/microRNA‑589‑5p/FOXP1 positive feedback loop increases the proliferation, migration and invasion of pancreatic cancer cell lines

Jing Zhao, Fang Wu, Jun Yang
Article Number: 794
Published online on: 17 September 2021

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Article Open Access

GHSR methylation‑dependent expression of a variant ligand and receptor of the ghrelin system induces thymoma tumorigenesis

Bilguun Tegshee, Kazuya Kondo, Shiho Soejima, Kyoka Muguruma, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku
Article Number: 793
Published online on: 17 September 2021

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Article

Four plasma miRNAs act as biomarkers for diagnosis and prognosis of non‑small cell lung cancer

He-Guo Jiang, Chun-Hua Dai, Ya-Ping Xu, Qian Jiang, Xian-Bin Xia, Yang Shu, Jian Li
Article Number: 792
Published online on: 17 September 2021

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Article Open Access

HMBS is the most suitable reference gene for RT‑qPCR in human HCC tissues and blood samples

Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Juan A Son, Donglim You, Jung Hwan Yoon, Hyoung Jung Cho, Soon Sun Kim, Jae Yeon Cheong, Jung Woo Eun
Article Number: 791
Published online on: 17 September 2021

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Article Open Access

Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity

Nanaka Morita, Masato Hoshi, Takeshi Hara, Soranobu Ninomiya, Taisuke Enoki, Misao Yoneda, Hisashi Tsurumi, Kuniaki Saito
Article Number: 790
Published online on: 17 September 2021

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Article Open Access

Microarray analysis of differentially expressed long non‑coding RNAs in daidzein‑treated lung cancer cells

Laifang Li, Jun Liu, Xiaobo Wang, Xiaowei Xiong, Shaoxin Huang, Xin Wang
Article Number: 789
Published online on: 17 September 2021

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Article Open Access

Efficacy and safety of humanized CD19 CAR‑T as a salvage therapy for recurrent CNSL of B‑ALL following murine CD19 CAR‑T cell therapy

Xin Li, Mei-Jing Liu, Nan Mou, Zhen-Xing Yang, Jia  Wang, Juan Mu, Hai-Bo Zhu, Qi Deng
Article Number: 788
Published online on: 16 September 2021

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Review Open Access

Immune checkpoints and immunotherapy in non‑small cell lung cancer: Novel study progression, challenges and solutions (Review)

Lin-Rui Ma, Jia-Xin Li, Ling Tang, Run-Ze Li, Jia-Shun Yang, Ao Sun, Elaine Lai‑Han Leung, Pei-Yu Yan
Article Number: 787
Published online on: 14 September 2021

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Article Open Access

Protein overexpression of toll‑like receptor 4 and myeloid differentiation factor 88 in oral squamous cell carcinoma and clinical significance

Lili Li, Zhuoqian Zhou, Khangvu Mai, Ping Li, Zongqi Wang, Yaxi Wang, Yang Cao, Xuemeng Ma, Tingting Zhang, Daiyou Wang
Article Number: 786
Published online on: 14 September 2021

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Review Open Access

An overview of mesenchymal stem cells and their potential therapeutic benefits in cancer therapy (Review)

Shern Kwok Lim, Boon Yin Khoo
Article Number: 785
Published online on: 14 September 2021

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Article Open Access

Maternally expressed 3 inhibits the biological activity of oral squamous cell carcinoma SCC25 and CAL27 cell lines

Wenjing Wang, Huanju Li, Yongle Qiu, Kunshan Li, Yueting Lu, Qianlan Deng, Tiejun Liu
Article Number: 784
Published online on: 13 September 2021

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Article Open Access

Effect of neutropenia on survival outcomes of patients with metastatic colorectal cancer receiving trifluridine/tipiracil plus bevacizumab

Daisaku Kamiimabeppu, Hiroki Osumi, Eiji Shinozaki, Akira Ooki, Takeru Wakatsuki, Koichiro Yoshino, Taro Sato, Izuma Nakayama, Mariko Ogura, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi
Article Number: 783
Published online on: 13 September 2021

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Article Open Access

NDRG4 sensitizes CRC cells to 5‑FU by upregulating DDIT3 expression Corrigendum in /10.3892/ol.2022.13321

Ruikai Li, Chenxiang He, Liangliang Shen, Shuai Wang, Yao Shen, Fan Feng, Jian Zhang, Jianyong Zheng
Article Number: 782
Published online on: 13 September 2021

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Article Open Access

Ferroptosis is involved in the anti‑tumor effect of lycorine in renal cell carcinoma cells

Yang Du, Hong-Chao Zhao, Heng-Cheng Zhu, Yao Jin, Lei Wang
Article Number: 781
Published online on: 13 September 2021

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Article

Identification of soluble tissue‑derived biomarkers from human thyroid tissue explants maintained on a microfluidic device

Andrew Riley, Heidi Jones, James England, Dmitriy Kuvshinov, Victoria Green, John Greenman
Article Number: 780
Published online on: 13 September 2021

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Article Open Access

Repurposing non‑invasive prenatal testing data: Population study of single nucleotide variants associated with colorectal cancer and Lynch syndrome

Natalia Forgacova, Juraj Gazdarica, Jaroslav Budis, Jan Radvanszky, Tomas Szemes
Article Number: 779
Published online on: 13 September 2021

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Article Open Access

Dynamic contrast‑enhanced MRI as a predictor of programmed death ligand‑1 expression in patients with oral squamous cell carcinoma

Nouha Tekiki, Mariko Fujita, Tatsuo Okui, Hotaka Kawai, May Wathone Oo, Toshiyuki Kawazu, Miki Hisatomi, Shunsuke Okada, Yohei Takeshita, Majd Barham, Hitoshi Nagatsuka, Yoshinobu Yanagi, Jun-Ichi Asaumi
Article Number: 778
Published online on: 13 September 2021

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Article Open Access

Construction and validation of nomograms for non‑metastatic Ewing sarcoma: A prognostic factor analysis based on the SEER database

Runzhi Huang, Dong Han, Chengcheng Shi, Penghui Yan, Peng Hu, Xiaolong Zhu, Huabin Yin, Tong Meng, Zongqiang Huang
Article Number: 777
Published online on: 13 September 2021

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Article Open Access

PET/MRI is useful for early detection of pelvic insufficiency fractures after radiotherapy for cervical cancer

Maho Azumi, Masuyo Matsumoto, Kaho Suzuki, Ryohei Sasaki, Yoshiko Ueno, Munenobu Nogami, Yoshito Terai
Article Number: 776
Published online on: 10 September 2021

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Review Open Access

Research progress concerning m6A methylation and cancer (Review)

Yang Zhou, Jie Yang, Zheng Tian, Jing Zeng, Weigan Shen
Article Number: 775
Published online on: 10 September 2021

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Article Open Access

Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma

Amos C. Hung, Yen-Yun Wang, Kun-Tsung Lee, Hung-Hsing Chiang, Yuk-Kwan Chen, Je-Kang Du, Chun-Ming Chen, Michael Yuanchien Chen, Kwei-Jing Chen, Stephen Chu-Sung Hu, Shyng-Shiou F. Yuan
Article Number: 774
Published online on: 10 September 2021

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Article Open Access

Long non‑coding RNA TMCC1‑AS1 predicts poor prognosis and accelerates epithelial‑mesenchymal transition in liver cancer Retraction in /10.3892/ol.2024.14785

Cheng Chen, Na Su, Guiying Li, Yanfeng Shen, Xiaoting Duan
Article Number: 773
Published online on: 09 September 2021

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Article Open Access

Long non‑coding RNA UCA1 enhances cervical cancer cell proliferation and invasion by regulating microRNA‑299‑3p expression

Ming An, Xuefeng Xing, Tonghua Chen
Article Number: 772
Published online on: 09 September 2021

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Article Open Access

Oncotype DX 21‑gene test has a low recurrence score in both pure and mixed mucinous breast carcinoma

Rui Chen, Yun Wang, Taolang Li, Junyuan Lv, Guoli Feng, Na Tan, Jinjing Wang, Xiaoming Cheng
Article Number: 771
Published online on: 09 September 2021

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Review Open Access

Cross‑link between ferroptosis and nasopharyngeal carcinoma: New approach to radiotherapy sensitization (Review)

Hai-Long Li, Nian-Hua Deng, Jia-Xin Xiao, Xiu-Sheng He
Article Number: 770
Published online on: 09 September 2021

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Article Open Access

Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling

Wei Hu, Mingxu Li, Junyi Wu, Hong Chen, Ting  Zhao, Chunjie Zhang, Zhong Wang
Article Number: 769
Published online on: 08 September 2021

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Article Open Access

Itraconazole improves survival outcomes in patients with colon cancer by inducing autophagic cell death and inhibiting transketolase expression

Pei-Wen Shen, Yu-Mei Chou, Chia-Ling Li, En-Chih Liao, Hung-Sen Huang, Chun-Hao Yin, Chien-Liang Chen, Sheng-Jie Yu
Article Number: 768
Published online on: 08 September 2021

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Article Open Access

Propofol induces the ferroptosis of colorectal cancer cells by downregulating STAT3 expression

Xining Zhao, Fei Chen
Article Number: 767
Published online on: 08 September 2021

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Article Open Access

Nanoscale Au@SiO2‑drug/VEGF as an in vivo probe for osteosarcoma diagnosis and therapy

Tiangui Chen, Tianbo Li, Jiangning Wang
Article Number: 766
Published online on: 08 September 2021

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Article Open Access

LAPTM4B promotes the progression of bladder cancer by stimulating cell proliferation and invasion

Yanhua Yin, Yanyan Fan, Gang Yu, Ying Du
Article Number: 765
Published online on: 08 September 2021

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Article Open Access

Double‑stranded RNA‑specific adenosine deaminase‑knockdown inhibits the proliferation and induces apoptosis of DU145 and PC3 cells by promoting the phosphorylation of H2A.X variant histone

Xiezhao Li, Rui Zhu, Yaoji Yuan, Zhiduan Cai, Siyang Liang, Jun Bian, Guibin Xu
Article Number: 764
Published online on: 08 September 2021

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Article Open Access

MicroRNA‑545‑5p regulates apoptosis, migration and invasion of osteosarcoma by targeting dimethyladenosine transferase 1

Hai-Zhen Zhou, Bo Chen, Xiao-Ju Li, Juan-Juan Du, Nan Zhang, Yu-Xiong Shao, Kun Zhang, Zhi-Chao Tong
Article Number: 763
Published online on: 06 September 2021

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Article Open Access

circRNA circ_POLA2 increases microRNA‑31 methylation to promote endometrial cancer cell proliferation

Xia Fang, Jinhua Wang, Lingying Chen, Xiaochun Zhang
Article Number: 762
Published online on: 06 September 2021

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Article Open Access

Role of NELF‑B in supporting epithelial‑mesenchymal transition and cell proliferation during hepatocellular carcinoma progression

Mennatallah Hani Ghouraba, Razan Jamil Masad, Eric Zadok Mpingirika, Omnia Mahmoud Abdelraheem, Rached Zeghlache, Aya M Alserw, Asma Amleh
Article Number: 761
Published online on: 06 September 2021

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Article Open Access

Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma

Patcharaporn Boottanun, Yoshinori Ino, Kazuaki Shimada, Nobuyoshi Hiraoka, Kiyohiko Angata, Hisashi Narimatsu
Article Number: 760
Published online on: 03 September 2021

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Article

Antiproliferative effect of GTS‑21 in glioblastoma cells

Malgorzata A. Kolodziej, Hanna Gött, Benjamin Kopischke, Michael K.F. Bender, Markus A. Weigand, Pietro Di Fazio, Frank P. Schwarm, Florian Uhle
Article Number: 759
Published online on: 02 September 2021

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Review Open Access

The mechanism of non‑coding RNAs in medulloblastoma (Review)

Ying-Nan Zhao, Kun Li, Xing-Sheng Han, Ya-Wen Pan
Article Number: 758
Published online on: 02 September 2021

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Article Open Access

Knockdown of lncRNA C5orf66‑AS1 inhibits osteosarcoma cell proliferation and invasion via miR‑149‑5p upregulation Corrigendum in /10.3892/ol.2025.15000

Hui Zhang, Jie Song
Article Number: 757
Published online on: 02 September 2021

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Article Open Access

UCHL3 plays an important role in the occurrence and development of melanoma

Runzhi He, Yajing Zhou, Jianmin Liu, Xiaochong Zhang, Xiaoling Zhao, Lihui An, Zihan Li, Fang Cheng
Article Number: 756
Published online on: 01 September 2021

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Article Open Access

T‑box 2 expression is a useful indicator of the response to neoadjuvant chemotherapy for patients with locally advanced uterine cervical squamous cell carcinoma

Yuta Inoue, Takeshi Fukuda, Shigenori Nanno, Yuichiro Awazu, Masahiro Shimomura, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 755
Published online on: 31 August 2021

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Article Open Access

EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 754
Published online on: 31 August 2021

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Article Open Access

Screening and identification of differentially expressed microRNAs in diffuse large B‑cell lymphoma based on microRNA microarray

Hai-Xia Gao, Si-Jing Li, Meng-Bo Wang, Shu-Fang Yan, Wen-Li Cui, Zhi-Ping Ma, Jing Xue, Wei Sang, Wei Zhang, Xin-Xia Li
Article Number: 753
Published online on: 27 August 2021

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Article Open Access

MicroRNA‑382‑5p inhibits osteosarcoma development and progression by negatively regulating VEZF1 expression

Hui Wu, Yu-Xi Luo, Wen Hu, Mao-Lin Zhao, Jun Bie, Mi Yang, Rongqiang Pan, Nan-Xiang Huang, Gang Feng, Kang Liu, Guiqin Song
Article Number: 752
Published online on: 27 August 2021

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Expression of oncogenic long noncoding RNA PSMG3‑antisense 1 in lung squamous cell carcinoma

E Jin, Chao Huang, Lei Zhang, Shiyi Chen, Xiaochen Zhao, Zheng Ren, Hong Fu
Article Number: 751
Published online on: 27 August 2021

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Progress on the study of the anticancer effects of artesunate (Review)

Xiulan Yang, Yudong Zheng, Lian Liu, Jiangrong Huang, Fei Wang, Jie Zhang
Article Number: 750
Published online on: 27 August 2021

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Anti‑Axl monoclonal antibodies attenuate the migration of MDA‑MB‑231 breast cancer cells

Hong Chang, Ran An, Xinying Li, Xiaoling Lang, Jiannan Feng, Ming Lv
Article Number: 749
Published online on: 27 August 2021

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Role of Toll‑like receptors in natural killer cell function in acute lymphoblastic leukemia (Review)

Janet Gallardo‑Zapata, Carmen Maldonado‑Bernal
Article Number: 748
Published online on: 24 August 2021

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CRMP5 regulates cell proliferation and development of colorectal cancer via MAPK‑dependent signaling

Fanghua Qiu, Lin Yu, Daoli Liu, Yujin Wu, Feng Qiu
Article Number: 747
Published online on: 24 August 2021

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A study on the clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography combined with serum squamous cell carcinoma antigen in diagnosing recurrence/metastases in patients with early metaphase cervical cancer

Chi Qi, Shasha He, Liang Cai, Li Zhang, Haoyuan Ding, Yue Chen
Article Number: 746
Published online on: 24 August 2021

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Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine, but not azacitidine, in acute myeloid leukemia with RAS mutations

Jihyun Park, Hyejoo Park, Ja Min Byun, Junshik Hong, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon
Article Number: 745
Published online on: 20 August 2021

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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