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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2018 Volume 18 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Oncostatin M promotes the osteogenic differentiation of mouse MC3T3‑E1osteoblasts through the regulation of monocyte chemotactic protein‑1

Wenbiao Zheng, Junhui Guan
Pages: 2523-2530
Published online on: 09 July 2018

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Article Open Access

Investigation of the role of cullin 4A overexpression in human liver cancer

Gang Chen, Xiongqi Zhao, Zedan Tan, Dongdong Wang, Ding Luo, Peiyao Zhang, Jun Cao, Fan Wang, Qiyu Liu, Li Li
Pages: 2531-2540
Published online on: 29 June 2018

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Article Open Access

Activation of the KEAP1‑NRF2‑ARE signaling pathway reduces oxidative stress in Hep2 cells

Changjiang Li, Lei Cheng, Haitao Wu, Peijie He, Yanping Zhang, Yue Yang, Jian Chen, Min Chen
Pages: 2541-2550
Published online on: 16 July 2018

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Article Open Access

Protective effects of compound ammonium glycyrrhizin, L‑arginine, silymarin and glucurolactone against liver damage induced by ochratoxin A in primary chicken hepatocytes

Zugong Yu, Feng Wu, Jing Tian, Xuewen Guo, Ran An
Pages: 2551-2560
Published online on: 16 July 2018

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Article Open Access

Aucubin suppresses Titanium particles‑mediated apoptosis of MC3T3‑E1 cells and facilitates osteogenesis by affecting the BMP2/Smads/RunX2 signaling pathway

Ziguan Zhu, Qingping Xie, Yazeng Huang, Shuijun Zhang, Yu Chen
Pages: 2561-2570
Published online on: 16 July 2018

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Article Open Access

miR‑200b‑3p inhibits proliferation and induces apoptosis in colorectal cancer by targeting Wnt1

Lijuan Chen, Xiangqun Wang, Yunhua Zhu, Jian Zhu, Qingzhong Lai
Pages: 2571-2580
Published online on: 16 July 2018

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Article Open Access

Lycium barbarum polysaccharides protect human trophoblast HTR8/SVneo cells from hydrogen peroxide‑induced oxidative stress and apoptosis

Jing Li, Zhongjun Ding, Yue Yang, Baohong Mao, Yanxia Wang, Xiaoying Xu
Pages: 2581-2588
Published online on: 12 July 2018

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Article

Protection of mouse pancreatic islet function by co‑culture with hypoxia pre‑treated mesenchymal stromal cells

Cheng Xiang, Qiu‑Ping Xie
Pages: 2589-2598
Published online on: 29 June 2018

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Article Open Access

Quercetin‑3‑O‑β‑D‑glucoside decreases the bioavailability of cyclosporin A through regulation of drug metabolizing enzymes, transporters and nuclear receptors in rats

Tingyu Yang, Yani Liu, Xixi Huang, Rui Zhang, Chunxiao Yang, Jiali Zhou, Yu Zhang, Jing Wan, Shaojun Shi
Pages: 2599-2612
Published online on: 03 July 2018

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Article Open Access

SH2B1 protects against OGD/R‑induced apoptosis in PC12 cells via activation of the JAK2/STAT3 signaling pathway

Jiang Yuan, Lei Zeng, Yanpeng Sun, Na Wang, Qiang Sun, Zhaohui Cheng, Yunfu Wang
Pages: 2613-2620
Published online on: 09 July 2018

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Article Open Access

miR‑185‑5p inhibits F‑actin polymerization and reverses epithelial mesenchymal transition of human breast cancer cells by modulating RAGE

Chonggao Yin, Guoxin Zhang, Ruimei Sun, Xinting Pan, Xuewen Wang, Hongli Li, Yunbo Sun
Pages: 2621-2630
Published online on: 16 July 2018

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Article Open Access

Downregulation of miR‑486‑5p in papillary thyroid carcinoma tissue: A study based on microarray and miRNA sequencing

Dong‑Yue Wen, Deng‑Hua Pan, Peng Lin, Qiu‑Yan Mo, Yun‑Peng Wei, Yi‑Huan Luo, Gang Chen, Yun He, Jun‑Qiang Chen, Hong Yang
Pages: 2631-2642
Published online on: 03 July 2018

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Article Open Access

Comprehensive analysis of gene expression profiles provides insight into the pathogenesis of Crohn's disease

Lumin Bo, Hongyu Fu, Junchi Yang
Pages: 2643-2650
Published online on: 09 July 2018

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Article Open Access

Candidate gene and mechanism investigations in congenital obstructive nephropathy based on bioinformatics analysis

Guangda Xin, Rui Chen, Xiaofei Zhang
Pages: 2651-2660
Published online on: 16 July 2018

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Article Open Access

MicroRNA‑665 suppresses the growth and migration of ovarian cancer cells by targeting HOXA10

Jinhui Liu, Yi Jiang, Yicong Wan, Shulin Zhou, Sunita Thapa, Wenjun Cheng
Pages: 2661-2668
Published online on: 05 July 2018

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Article Open Access

Analysis of non‑alcoholic fatty liver disease microRNA expression spectra in rat liver tissues

Jiao Nie, Chang‑Ping Li, Jue‑Hong Li, Xia Chen, Xiaoling Zhong
Pages: 2669-2680
Published online on: 09 July 2018

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Article Open Access

Parathyroid hormone 1‑34 inhibits senescence in rat nucleus pulposus cells by activating autophagy via the m‑TOR pathway

Xiao‑Ying Wang, Li‑Yan Jiao, Jing‑Lan He, Zhi‑An Fu, Ru‑Jun Guo
Pages: 2681-2688
Published online on: 27 June 2018

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Article Open Access

MiR‑500a‑5p promotes glioblastoma cell proliferation, migration and invasion by targeting chromodomain helicase DNA binding protein 5

Zhiyong Liu, Danying Su, Xiuying Qi, Jing Ma
Pages: 2689-2696
Published online on: 09 July 2018

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Article Open Access

Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways

Xiaojian Huang, Qiyong Pan, Zekai Mao, Pengcheng Wang, Rui Zhang, Xiaohu Ma, Jingyuan Chen, Hongbo You
Pages: 2697-2704
Published online on: 16 July 2018

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Article Open Access

Effect of cellular mass on chondrogenic differentiation during embryoid body formation

Michał Stefan Lach, Katarzyna Kulcenty, Karolina Jankowska, Tomasz Trzeciak, Magdalena Richter, Wiktoria Maria Suchorska
Pages: 2705-2714
Published online on: 10 July 2018

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Article Open Access

Candidate genes and microRNAs for glioma pathogenesis and prognosis based on gene expression profiles

Chen Xie, Meng Xu, Dejuan Lu, Weiguang Zhang, Laizang Wang, Hongwei Wang, Jianhua Li, Fubin Ren, Chao Wang
Pages: 2715-2723
Published online on: 29 June 2018

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Article Open Access

Low‑frequency ultrasound and microbubbles combined with simvastatin promote the apoptosis of MCF‑7 cells by affecting the LATS1/YAP/RHAMM pathway

Haige Li, Chen Chen, Dehang Wang
Pages: 2724-2732
Published online on: 12 July 2018

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Article Open Access

‘Psoriasis 1’ reduces psoriasis‑like skin inflammation by inhibiting the VDR‑mediated nuclear NF‑κB and STAT signaling pathways

Wen Sun, Yang Gao, Xianhua Yu, Yuan Yuan, Jun Yi, Zhen Zhang, Yuxing Cheng, Yong Li, Xing Peng, Xushan Cha
Pages: 2733-2743
Published online on: 09 July 2018

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Article Open Access

ROS‑mediated autophagy through the AMPK signaling pathway protects INS‑1 cells from human islet amyloid polypeptide‑induced cytotoxicity

Guanghao Xia, Tiehong Zhu, Xiaotong Li, Yujing Jin, Jing Zhou, Jinfeng Xiao
Pages: 2744-2752
Published online on: 03 July 2018

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Article Open Access

miR-577 suppresses cell proliferation and epithelial-mesenchymal transition by regulating the WNT2B mediated Wnt/β-catenin pathway in non-small cell lung cancer

Bin Wang, Liwei Sun, Jinduo Li, Rong Jiang
Pages: 2753-2761
Published online on: 16 July 2018

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Article Open Access

Comparison of target volume and clinical effects of four radiotherapy plans for acute lymphoblastic leukemia prior to hematopoietic stem cell transplantation

Yalei Lin, Fanyang Kong, Hongfei Li, Dandan Xu, Fei Jia, Xudong Zhang, Baohong Wang, Guowen Li
Pages: 2762-2770
Published online on: 27 June 2018

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Article Open Access

Downregulation of microRNA‑21 expression inhibits proliferation, and induces G1 arrest and apoptosis via the PTEN/AKT pathway in SKM‑1 cells

Guang Li, Yanping Song, Gangcan Li, Jingjing Ren, Jia Xie, Yunjie Zhang, Fei Gao, Jiao Mu, Jinqian Dai
Pages: 2771-2779
Published online on: 05 July 2018

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Article Open Access

Short‑term use of atorvastatin affects glucose homeostasis and suppresses the expression of LDL receptors in the pancreas of mice

Qi Yu, Fang Wang, Xiaodong Meng, Yiren Gong, Yanli Wang, Cangbao Xu, Siwang Wang
Pages: 2780-2788
Published online on: 03 July 2018

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Article Open Access

Integrative analysis of promising molecular biomarkers and pathways for coronary artery disease using WGCNA and MetaDE methods

Shilin Yan
Pages: 2789-2797
Published online on: 16 July 2018

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Article Open Access

MicroRNA‑155 promotes ox‑LDL‑induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway

Shuangshuang Yin, Shaonan Yang, Xudong Pan, Aijun Ma, Juanjuan Ma, Haotian Pei, Yi Dong, Shu Li, Wei Li, Xinran Bi
Pages: 2798-2806
Published online on: 29 June 2018

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Article Open Access

Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury

Tingting Fang, Ruiping Cao, Wenlian Wang, Hongwei Ye, Lin Shen, Zhenghong Li, Junfeng Hu, Qin Gao
Pages: 2807-2815
Published online on: 09 July 2018

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Article Open Access

Identification of a novel idiopathic congenital nystagmus‑causing missense mutation, p.G296C, in the FRMD7 gene

Yanghui Xiu, Yihua Yao, Tanchu Yang, Meihua Pan, Hui Yang, Weifang Fang, Feng Gu, Junzhao Zhao, Yihua Zhu
Pages: 2816-2822
Published online on: 09 July 2018

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Article Open Access

Inhibitory effect of timolol on topical glucocorticoid‑induced skin telangiectasia

Yan‑Fei Li, Xiao‑Yan Chen, Tie‑Chi Lei
Pages: 2823-2831
Published online on: 09 July 2018

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Article Open Access

Eotaxin‑1 and MCP‑1 serve as circulating indicators in response to power frequency electromagnetic field exposure in mice

Hualiang Li, Lin Lin, Li Li, Liang Zhou, Shuai Hao, Ying Zhang, Zhenhua Ding
Pages: 2832-2840
Published online on: 29 June 2018

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Article Open Access

Bioinformatics approach reveals the key role of C‑X‑C motif chemokine receptor 2 in endometriosis development

Aili Tan, Ruoyu Luo, Hua Liang, Mengru Li, Peng Ruan
Pages: 2841-2849
Published online on: 12 July 2018

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Article Open Access

Long non‑coding RNA HR1 participates in the expression of SREBP‑1c through phosphorylation of the PDK1/AKT/FoxO1 pathway Corrigendum in /10.3892/mmr.2024.13161

Duan Li, Liwei Guo, Baoguo Deng, Min Li, Tingting Yang, Fan Yang, Zhijun Yang
Pages: 2850-2856
Published online on: 16 July 2018

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Article Open Access

Bioinformatic analysis of microRNA expression in Huntington's disease

Xiaoyu Dong, Shuyan Cong
Pages: 2857-2865
Published online on: 29 June 2018

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Article Open Access

miR‑140‑5p regulates cell migration and invasion of non‑small cell lung cancer cells through targeting VEGFA

Peixia Yang, Jie Xiong, Lin Zuo, Kequn Liu, Houbin Zhang
Pages: 2866-2872
Published online on: 16 July 2018

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Article Open Access

RBP4 regulates trophoblastic cell proliferation and invasion via the PI3K/AKT signaling pathway

Hongxia Li, Guangming Cao, Nawei Zhang, Tong Lou, Qiushi Wang, Zhenyu Zhang, Chongdong Liu
Pages: 2873-2879
Published online on: 03 July 2018

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Article Open Access

Corosolic acid reduces 5‑FU chemoresistance in human gastric cancer cells by activating AMPK

Jun Beom Park, Jin Sun Lee, Myung Sun Lee, Eun Young Cha, Soyeon Kim, Ji Young Sul
Pages: 2880-2888
Published online on: 03 July 2018

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Article Open Access

Rapid diagnosis of human adenovirus B, C and E in the respiratory tract using multiplex quantitative polymerase chain reaction

Yuhong Dou, Yuxia Li, Caifeng Ma, Huijun Zhu, Jikun Du, Helu Liu, Qiong Liu, Rui Chen, Ying Tan
Pages: 2889-2897
Published online on: 05 July 2018

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Article Open Access

Establishment of a novel non‑alcoholic fatty liver disease model using cholesterol‑fed rabbits with reference to the potential role of endoplasmic reticulum stress

Yanli Wang, Peng Zhang, Xingli Su, Qi Yu, Yulong Chen, Hua Guan, Enqi Liu, Jianglin Fan
Pages: 2898-2904
Published online on: 06 July 2018

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Article Open Access

Rottlerin promotes autophagy and apoptosis in gastric cancer cell lines

Jun Song, Yan Zhou, Yu Gong, Hanyang Liu, Liming Tang
Pages: 2905-2913
Published online on: 16 July 2018

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Article

Luteolin inhibits angiogenesis of the M2‑like TAMs via the downregulation of hypoxia inducible factor‑1α and the STAT3 signalling pathway under hypoxia

Binbo Fang, Xuehai Chen, Minmin Wu, Hongru Kong, Guanyu Chu, Zhenxu Zhou, Chunwu Zhang, Bicheng Chen
Pages: 2914-2922
Published online on: 03 July 2018

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Article

Sevoflurane attenuates ventilator‑induced lung injury by regulating c‑PLA2 expression

Yong Yang, Wen‑Fa Wang, Yan‑Hua Li, Li‑Sha Li, Xin Guo, Rui Liu
Pages: 2923-2928
Published online on: 03 July 2018

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Article

Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest

Dong Wang, Xinjie Zhang, Daoxu Qu, Jichun Han, Fanqing Meng, Minglei Xu, Qiusheng Zheng
Pages: 2929-2936
Published online on: 05 July 2018

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Article

Elevated HTRA1 and HTRA4 in severe preeclampsia and their roles in trophoblast functions

Chunhong Liu, Feng Xing, Yuanying He, Shanshan Zong, Chengfeng Luo, Chunqing Li, Tao Duan, Kai Wang, Qian Zhou
Pages: 2937-2944
Published online on: 16 July 2018

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Article

MicroRNA‑29a contributes to intracranial aneurysm by regulating the mitochondrial apoptotic pathway

Wenjing Zhao, Haifang Zhang, Jin‑Ying Su
Pages: 2945-2954
Published online on: 06 July 2018

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Article

Tanshinone IIA attenuates paraquat‑induced acute lung injury by modulating angiotensin‑converting enzyme 2/angiotensin‑(1‑7) in rats

Yanxia Wang, Huajie Wu, Wen Niu, Jian Chen, Manlin Liu, Xin Sun, Zhichao Li
Pages: 2955-2962
Published online on: 16 July 2018

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Article

Expression of transmembrane protein 41A is associated with metastasis via the modulation of E‑cadherin in radically resected gastric cancer

Bin Lin, Yingming Xue, Chao Qi, Xiangjie Chen, Weizheng Mao
Pages: 2963-2972
Published online on: 03 July 2018

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Article

PTEN enhances nasal epithelial cell resistance to TNFα‑induced inflammatory injury by limiting mitophagy via repression of the TLR4‑JNK‑Bnip3 pathway

Meng Li, Xiang Yang, Shouchuan Wang
Pages: 2973-2986
Published online on: 09 July 2018

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Article

Spilanthol inhibits TNF‑α‑induced ICAM‑1 expression and pro‑inflammatory responses by inducing heme oxygenase‑1 expression and suppressing pJNK in HaCaT keratinocytes

Chun‑Hsun Huang, Li‑Chun Chang, Sindy Hu, Chien‑Yu Hsiao, Shu‑Ju Wu
Pages: 2987-2994
Published online on: 03 July 2018

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Article

Associations of CXCL16, miR‑146a and miR‑146b in atherosclerotic apolipoprotein E‑knockout mice

Ai‑Jun Ma, Xiao‑Yan Zhu, Shao‑Nan Yang, Xu‑Dong Pan, Ting Wang, Yuan Wang, Xing Xiao, Shi‑Hai Liu
Pages: 2995-3002
Published online on: 10 July 2018

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Article

Network‑based gene function inference method to predict optimal gene functions associated with fetal growth restriction

Ke‑Jun Ye, Jie Dai, Ling‑Yun Liu, Meng‑Jia Peng
Pages: 3003-3010
Published online on: 29 June 2018

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Article

Obtusifolin inhibits high glucose‑induced mitochondrial apoptosis in human umbilical vein endothelial cells

Yu Tang, Zhi‑Ying Zhong, Yan‑Feng Liu, Gou‑Tai Sheng
Pages: 3011-3019
Published online on: 05 July 2018

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Article

Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer

Ke Jing, Qinsheng Mao, Peng Ma
Pages: 3020-3026
Published online on: 27 June 2018

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Article

P2X7 receptor regulates EMMPRIN and MMP‑9 expression through AMPK/MAPK signaling in PMA‑induced macrophages

Lu Lin, Shanjun Huang, Zhouyang Zhu, Jibo Han, Zhengxian Wang, Weijian Huang, Zhouqing Huang
Pages: 3027-3033
Published online on: 16 July 2018

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Article

Differential responses of GC‑1 spermatogonia cells to high and low doses of bisphenol A

Yuhua Li, Fei Duan, Xiaoyu Zhou, Hongjie Pan, Runsheng Li
Pages: 3034-3040
Published online on: 06 July 2018

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Article

Triptolide exhibits antitumor effects by reversing hypermethylation of WIF‑1 in lung cancer cells

Xiaoliang Mao, Jichun Tong, Yong Wang, Zheng Zhu, Yajun Yin, Yeming Wang
Pages: 3041-3049
Published online on: 09 July 2018

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Article

Prevalence of hyperuricemia among the Chinese population of the southeast coastal region and association with single nucleotide polymorphisms in urate‑anion exchanger genes: SLC22A12, ABCG2 and SLC2A9

Xinran Yang, Yingxiu Xiao, Kaixi Liu, Xiaoyang Jiao, Xiaozhe Lin, Yongni Wang, Qiaoxin Zhang
Pages: 3050-3058
Published online on: 16 July 2018

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Article

Long non‑coding RNA UCA1 promotes papillary thyroid cancer cell proliferation via miR‑204‑mediated BRD4 activation

Dong Li, Chuanyou Cui, Jing Chen, Zhifang Hu, Yonghui Wang, Dongyu Hu
Pages: 3059-3067
Published online on: 03 July 2018

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Article

Long noncoding RNA UCA1 promotes anaplastic thyroid cancer cell proliferation via miR‑135a‑mediated c‑myc activation

Yonghui Wang, Zhengguang Hou, Dong Li
Pages: 3068-3076
Published online on: 16 July 2018

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Article

MicroRNA‑130a inhibits the proliferation, migration and invasive ability of hepatocellular carcinoma cells by downregulating Rho‑kinase 2

Yansong Zheng, Liangguang Xiang, Mingliu Chen, Chunhui Xiang
Pages: 3077-3084
Published online on: 16 July 2018

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Dysregulation of CD69 by overexpression of microRNA‑367‑3p associated with post‑myocardial infarction cardiac fibrosis

Haiyan Hu, Jing Li, Jingfang Zhang
Pages: 3085-3092
Published online on: 29 June 2018

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Article

Association between the HMGB1/TLR4 signaling pathway and the clinicopathological features of ovarian cancer

Caixia Jiang, Xiaoyan Qu, Huihui Ke, Wei Gong, Rong Chen, Weihong Yang, Zhongping Cheng
Pages: 3093-3098
Published online on: 10 July 2018

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Article

MicroRNA‑874 prohibits the proliferation and invasion of retinoblastoma cells by directly targeting metadherin Retraction in /10.3892/mmr.2022.12900

Yongfeng Zhang, Xueqin Wang, Yuehua Zhao
Pages: 3099-3105
Published online on: 16 July 2018

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Article

MicroRNA‑655 suppresses cell proliferation and invasion in oral squamous cell carcinoma by directly targeting metadherin and regulating the PTEN/AKT pathway Retraction in /10.3892/mmr.2022.12897

Qiang Wang, Longkun Lv, Yuan Li, Honghai Ji
Pages: 3106-3114
Published online on: 16 July 2018

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Correction Open Access

[Corrigendum] Neurotoxin β‑N‑methylamino‑L‑alanine induces endoplasmic reticulum stress‑mediated neuronal apoptosis

Haiying Shen, Kiyoon Kim, Yoojung Oh, Kyung Sik Yoon, Hyung Hwan Baik, Sung Soo Kim, Joohun Ha, Insug Kang, Wonchae Choe
Pages: 3115-3115
Published online on: 03 July 2018

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Review Open Access

The bimodal role of matrix metalloproteinases and their inhibitors in etiology and pathogenesis of endometriosis (Review)

Magdalenia Bałkowiec, Radosław B. Maksym, Paweł K. Włodarski
Pages: 3123-3136
Published online on: 23 July 2018

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Anesthetic agent etiomidate induces apoptosis in N2a brain tumor cell line

Hong‑Tao Chen, Jun Zhou, You‑Ling Fan, Chun‑Liang Lei, Bao‑Jin Li, Li‑Xin Fan, Li Xu, Ming Xu, Xiu‑Qin Hu, Zhi‑Ying Yu
Pages: 3137-3142
Published online on: 19 July 2018

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Extracellular matrix promotes proliferation, migration and adhesion of airway smooth muscle cells in a rat model of chronic obstructive pulmonary disease via upregulation of the PI3K/AKT signaling pathway

Zhengyan Wang, Rui Li, Rui Zhong
Pages: 3143-3152
Published online on: 25 July 2018

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Mutation and expression of ABCA12 in keratosis pilaris and nevus comedonicus

Fen Liu, Yao Yang, Yan Zheng, Yan‑Hua Liang, Kang Zeng
Pages: 3153-3158
Published online on: 31 July 2018

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Alda‑1, an aldehyde dehydrogenase‑2 agonist, improves long‑term survival in rats with chronic heart failure following myocardial infarction

Yue Hua, Hongmei Chen, Xinyun Zhao, Min Liu, Wen Jin, Wen Yan, Yifen Wu, Zhangbin Tan, Huijie Fan, Yuting Wu, Lingpeng Xie, Wentong Zhang, Bin Liu, Yingchun Zhou
Pages: 3159-3166
Published online on: 24 July 2018

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LncRNA and mRNA interaction study based on transcriptome profiles reveals potential core genes in the pathogenesis of human thoracic aortic dissection

Yang Li, Nan Yang, Xianbao Zhou, Xuezhi Bian, Genqiang Qiu, Mo Zhang, Huagang Lin, Dingfeng Li
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Published online on: 23 July 2018

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Simvastatin improves cerebrovascular injury caused by ischemia‑reperfusion through NF‑κB‑mediated apoptosis via MyD88/TRIF signaling

Zhiying Chen, Yuanyuan Xiang, Bing Bao, Xiangbin Wu, Zhongbin Xia, Jianyou You , Hongbing Nie
Pages: 3177-3184
Published online on: 30 July 2018

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Ginkgolide K protects SH‑SY5Y cells against oxygen‑glucose deprivation‑induced injury by inhibiting the p38 and JNK signaling pathways

Qiu Liu, Xueke Li, Liang Li, Zhiliang Xu, Jun Zhou, Wei Xiao
Pages: 3185-3192
Published online on: 23 July 2018

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Glassy carbon electrode modified with G‑MoS2‑Nafion acts as an electrochemical biosensor to determine uric acid in human serum

Bo Yan, Dongsheng Wang, Qiang Wang, Xiaolan Lu, Qin Du, Qi Liang, Xingliang Jiang, Xiaolan Guo, Jingguo Zhou, Yan Xing
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Role of microRNA 146a on the healing of cornea alkali burn treated with mesenchymal stem cells

Xu Luo, Jianmin Li, Lihui Yin, Jian Pan, Yang Zhang, Zipei Jiang
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Published online on: 27 July 2018

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Therapeutic effect of chitosan on CCl4‑induced hepatic fibrosis in rats

Zhong‑Feng Wang, Mao‑Yu Wang, De‑Hai Yu, Yan Zhao, Hong‑Mei Xu, Sheng Zhong, Wen‑Yi Sun, Yu‑Fang He, Jun‑Qi Niu, Pu‑Jun Gao, Hai‑Jun Li
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MicroRNA‑143‑3p contributes to the regulation of pain responses in collagen‑induced arthritis

Ling‑Ling Zhou, Ya‑Mei Zhu, Fei‑Ya Qian, Cheng‑Chen Yuan, Dong‑Ping Yuan, Xue‑Ping Zhou
Pages: 3219-3228
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Effect of fermented Cordyceps sinensis on doxorubicin‑induced cardiotoxicity in rats

Rong Wu, Ping‑An Yao, Hui‑Lin Wang, Yan Gao, Hai‑Lun Yu, Lei Wang, Xiao‑Hua Cui, Xu Xu, Jian‑Ping Gao
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Ultrasound‑targeted microbubble destruction‑mediated miR‑205 enhances cisplatin cytotoxicity in prostate cancer cells

Dingwen Qin, Haige Li, Honglin Xie
Pages: 3242-3250
Published online on: 24 July 2018

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Role of autophagy in a model of obesity: A long‑term high fat diet induces cardiac dysfunction

Yan Che, Zhao‑Peng Wang, Yuan Yuan, Ning Zhang, Ya‑Ge Jin, Chun‑Xia Wan, Qi‑Zhu Tang
Pages: 3251-3261
Published online on: 23 July 2018

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Emodin alleviates CCl4‑induced liver fibrosis by suppressing epithelial‑mesenchymal transition and transforming growth factor‑β1 in rats

Feng Liu, Jing Zhang, Jianmin Qian, Gang Wu, Zhenyu Ma
Pages: 3262-3270
Published online on: 26 July 2018

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MNX1 reduces sensitivity to anoikis by activating TrkB in human glioma cells

Lai Jiang, Shaojun Chen, Donggang Zhao, Jun Yan, Jiemin Chen, Chunlin Yang, Gang Zheng
Pages: 3271-3279
Published online on: 27 July 2018

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Silencing Tspan1 inhibits migration and invasion, and induces the apoptosis of human pancreatic cancer cells

Jiaxun Tian, Rui Zhang, Haiyan Piao, Xiaoxi Li, Weiwei Sheng, Jianping Zhou, Ming Dong, Xiaobo Zhang, Xiaofei Yan, Wen Shang, Jianfeng Zhao, Lan Xu, Fang Liu, Gang Shi
Pages: 3280-3288
Published online on: 27 July 2018

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A random forest classifier predicts recurrence risk in patients with ovarian cancer

Li Cheng, Lin Li, Liling Wang, Xiaofang Li, Hui Xing, Jinting Zhou
Pages: 3289-3297
Published online on: 19 July 2018

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Cocaine‑ and amphetamine‑regulated transcript (CART) is associated with dopamine and is protective against ischemic stroke

Lili Lin, Da Sun, Jing Chang, Ming Ma, Xiaoying Zhou, Min Zhao, Jian Li
Pages: 3298-3304
Published online on: 19 July 2018

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Diagnostic utility of plasma lncRNA small nucleolar RNA host gene 1 in patients with hepatocellular carcinoma

Shoubao Gao, Xiaohong Xu, Yue Wang, Wei Zhang, Xingye Wang
Pages: 3305-3313
Published online on: 30 July 2018

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Screening of exosomal miRNAs derived from subcutaneous and visceral adipose tissues: Determination of targets for the treatment of obesity and associated metabolic disorders

Zheng Yang, Zhuying Wei, Xia Wu, Huidi Yang
Pages: 3314-3324
Published online on: 24 July 2018

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Icariin induces the growth, migration and osteoblastic differentiation of human periodontal ligament fibroblasts by inhibiting Toll-like receptor 4 and NF-κB p65 phosphorylation

Hai-Jiang Liu, Xue-Yang Liu, De-Bao Jing
Pages: 3325-3331
Published online on: 23 July 2018

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The protective effects of total paeony glycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway

Peihong Shen, Junfeng Chen, Min Pan
Pages: 3332-3340
Published online on: 30 July 2018

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Murine and Chinese cobra venom‑derived nerve growth factor stimulate chondrogenic differentiation of BMSCs in vitro: A comparative study Corrigendum in /10.3892/mmr.2021.12444

Zhikang Miao, Zhenhui Lu, Shixing Luo, Danqing Lei, Yi He, Huayu Wu, Jinmin Zhao, Li Zheng
Pages: 3341-3349
Published online on: 23 July 2018

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Exendin‑4 reverses endothelial dysfunction in mice fed a high‑cholesterol diet by a GTP cyclohydrolase‑1/tetrahydrobiopterin pathway

Zhiqi Tang, Lijuan Liu, Yujie Guo, Guoxiong Deng, Meixiang Chen, Jinru Wei
Pages: 3350-3358
Published online on: 01 August 2018

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Role of miR‑449b‑3p in endometriosis via effects on endometrial stromal cell proliferation and angiogenesis

Yukai Liu, Jie Chen, Xiaoyong Zhu, Lingli Tang, Xuezhen Luo, Yingli Shi
Pages: 3359-3365
Published online on: 31 July 2018

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Emodin inhibits pancreatic cancer EMT and invasion by up‑regulating microRNA‑1271

Nan Li, Chunli Wang, Peng Zhang, Shengyi You
Pages: 3366-3374
Published online on: 23 July 2018

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Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells

Ying Xia, Zhiqiang Yan, Ying Wan, Sixi Wei, Ying Bi, Juanjuan Zhao, Juanjuan Liu, Dezhong Joshua Liao, Hai Huang
Pages: 3375-3381
Published online on: 27 July 2018

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Article

UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway

Xueli Shi, Liu Yang, Jun Xie, Yumei Zhao, Junzi Cong, Zhiping Li, Haiyan Li, Xianzhi Cheng, Jinghui Fan
Pages: 3382-3388
Published online on: 25 July 2018

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Hepatocyte growth factor exerts beneficial effects on mice with type II diabetes‑induced chronic renal failure via the NF‑κB pathway

Guiming Cheng, Xun Tang, Jun Zhang
Pages: 3389-3396
Published online on: 19 July 2018

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Article

Knockdown of miR‑935 increases paclitaxel sensitivity via regulation of SOX7 in non‑small‑cell lung cancer

Bing Peng, Chao Li, Peng Cai, Liuyang Yu, Bolin Zhao, Guiming Chen
Pages: 3397-3402
Published online on: 27 July 2018

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Increased expression of TNFRSF14 indicates good prognosis and inhibits bladder cancer proliferation by promoting apoptosis

Yu‑Di Zhu, Ming‑Yue Lu
Pages: 3403-3410
Published online on: 23 July 2018

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TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells

Kunlin Wu, Huihao Zhang, Yajuan Fu, Youzhi Zhu, Lingjun Kong, Ling Chen, Feng Zhao, Liangfei Yu, Xiangjin Chen
Pages: 3411-3420
Published online on: 26 July 2018

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Article

PPARγ agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation

Wen‑Da Wang, Rui Sun, Yue‑Xin Chen
Pages: 3421-3428
Published online on: 24 July 2018

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Article

Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway

Xiu‑Rong Zhang, Shi‑Yao Wang, Wen Sun, Chao Wei
Pages: 3429-3436
Published online on: 25 July 2018

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Article

Cognitive impairments induced by severe acute pancreatitis are attenuated by berberine treatment in rats

Xiaofeng Ou, Yusi Hua, Xuelian Liao, Cansheng Gong, Yan Kang
Pages: 3437-3444
Published online on: 24 July 2018

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Article

Icariin promotes the proliferation and differentiation of osteoblasts from the rat mandible by the Wnt/β‑catenin signalling pathway

Yue Wang, Ran Wang, Fengqiu Zhang
Pages: 3445-3450
Published online on: 30 July 2018

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Article

Long noncoding RNA TUG1 promotes cardiac fibroblast transformation to myofibroblasts via miR‑29c in chronic hypoxia

Yun Zhu, Zezhou Feng, Zhao Jian, Yingbin Xiao
Pages: 3451-3460
Published online on: 27 July 2018

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Article

Triticum aestivum sprout extract attenuates 2,4‑dinitrochlorobenzene‑induced atopic dermatitis‑like skin lesions in mice and the expression of chemokines in human keratinocytes

Ji‑Hyun Lee, Hyeon‑Hui Ki, Dae‑Ki Kim, Young‑Mi Lee
Pages: 3461-3468
Published online on: 31 July 2018

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Article

Decreased SUMOylation of the retinoblastoma protein in keratinocytes during the pathogenesis of vitiligo

Miaoni Zhou, Fuquan Lin, Wen Xu, Rong Jin, Aie Xu
Pages: 3469-3475
Published online on: 19 July 2018

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Article

Shikonin‑mediated inhibition of nestin affects hypoxia‑induced proliferation of pulmonary artery smooth muscle cells

Susu He, Jian Lin, Ling Lin, Youzu Xu, Jiaxi Feng
Pages: 3476-3482
Published online on: 30 July 2018

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Article

Icariin stimulates osteogenic differentiation and suppresses adipogenic differentiation of rBMSCs via estrogen receptor signaling

Xiaoyun Li, Bojia Peng, Yanbin Pan, Panpan Wang, Kehuan Sun, Xiaotong Lei, Ling Ou, Zhidi Wu, Xiaoguang Liu, Haixia Wang, Haibin He, Shu Mo, Ya Tian, Xunqian Peng, Xiaofeng Zhu, Ronghua Zhang, Li Yang
Pages: 3483-3489
Published online on: 26 July 2018

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Article

shRNA knockdown of DNA helicase ERCC6L expression inhibits human breast cancer growth

Juan Liu, Jing Sun, Qian Zhang, Zhaochong Zeng
Pages: 3490-3496
Published online on: 25 July 2018

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Article

Melatonin protects H9c2 cells against ischemia/reperfusion‑induced apoptosis and oxidative stress via activation of the Nrf2 signaling pathway

Yan Zhang, Baoguang Qiao, Fei Gao, Haifeng Wang, Shaohua Miao, Huan Zhao
Pages: 3497-3505
Published online on: 24 July 2018

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Article

Urate crystals induce macrophage PAF‑AH secretion which is differentially regulated by TGFβ1 and hydrocortisone

Darshna Yagnik, Frank Hills
Pages: 3506-3512
Published online on: 26 July 2018

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Article

NSD2 is downregulated in T2DM and promotes β cell proliferation and insulin secretion through the transcriptionally regulation of PDX1

Suqin Shi, Lu Zhao, Lili Zheng
Pages: 3513-3520
Published online on: 31 July 2018

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Article

MicroRNA‑376a inhibits cell proliferation and invasion in osteosarcoma via directly targeting SATB1

Guanghong Zhou, Hao Jiang, Liping Ma
Pages: 3521-3528
Published online on: 01 August 2018

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Article

Increased mitochondrial common deletion in platelets from patients with type 2 diabetes is not associated with abnormal platelet activity or mitochondrial function

Ayla Karimova, Yalçin Hacioğlu, Nurten Bahtiyar, Mutlu Niyazoğlu, Fahri Akbaş, Erkan Yilmaz, Turgut Ulutin, Ilhan Onaran
Pages: 3529-3536
Published online on: 31 July 2018

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Article

Effects of aloe polysaccharide, a polysaccharide extracted from Aloe vera, on TNF‑α‑induced HaCaT cell proliferation and the underlying mechanism in psoriasis

Hong Leng, Li Pu, Longjiang Xu, Xin Shi, Jiang Ji, Kun Chen
Pages: 3537-3543
Published online on: 25 July 2018

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October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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November-2026 Volume 34 Issue 5

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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