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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2015 Volume 12 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Epigenetic dysregulation of endometriosis susceptibility genes (Review)

Natsuki Koike, Yumi Higashiura, Juria Akasaka, Chiharu Uekuri, Fuminori Ito, Hiroshi Kobayashi
Pages: 1611-1616
Published online on: 16 April 2015

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Review

Apolipoprotein M: Research progress, regulation and metabolic functions (Review)

Li‑Zhu Huang, Jia‑Lin Gao, Chun Pu, Pu‑Hong Zhang, Li‑Zhuo Wang, Gang Feng, Yao Zhang
Pages: 1617-1624
Published online on: 22 April 2015

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Article Open Access

Salicylate-induced changes in immediate-early genes in the hippocampal CA1 area

Hao Wu, Feng‑Lei Xu, Yong Yin, Peng Da, Xiao‑Dong You, Hui‑Min Xu, Yan Tang
Pages: 1625-1630
Published online on: 14 April 2015

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Article Open Access

Effect and mechanism of poly (ADP-ribose) polymerase-1 in aldosterone-induced apoptosis

Weiwei Qiao, Weili Zhang, Shuhong Shao, Yusheng Gai, Mingxiang Zhang
Pages: 1631-1638
Published online on: 07 April 2015

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Article Open Access

Betaine inhibits vascularization via suppression of Akt in the retinas of streptozotocin-induced hyperglycemic rats

Young‑Giun Kim, Hyung‑Ho Lim, Suh‑Ha Lee, Mal‑Soon Shin, Chang‑Ju Kim, Hyeon Jeong Yang
Pages: 1639-1644
Published online on: 15 April 2015

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Article Open Access

Combining radiation with autophagy inhibition enhances suppression of tumor growth and angiogenesis in esophageal cancer

Yongshun Chen, Xiaohong Li, Leiming Guo, Xiaoyuan Wu, Chunyu He, Song Zhang, Yanjing Xiao, Yuanyuan Yang, Daxuan Hao
Pages: 1645-1652
Published online on: 16 April 2015

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Article Open Access

Downregulation of inhibitor of apoptosis‑stimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells

Lu‑Lu Wang, Zhong Xu, Yang Peng, Lu‑Chun Li, Xiao‑Ling Wu
Pages: 1653-1658
Published online on: 01 April 2015

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Article Open Access

Effects of the ninein‑like protein centrosomal protein on breast cancer cell invasion and migration

Qi Liu, Xinzhao Wang, Minlin Lv, Dianbin Mu, Leilei Wang, Wensu Zuo, Zhiyong Yu
Pages: 1659-1664
Published online on: 20 April 2015

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Article Open Access

Establishment of an interleukin‑1β‑induced inflammation‑activated endothelial cell‑smooth muscle cell‑mononuclear cell co‑culture model and evaluation of the anti‑inflammatory effects of tanshinone IIA on atherosclerosis

Yujie Li, Yan Guo, Ying Chen, Yajie Wang, Yun You, Qing Yang, Xiaogang Weng, Qi Li, Xiaoxin Zhu, Bingbing Zhou, Xucen Liu, Zaipeng Gong, Ruijie Zhang
Pages: 1665-1676
Published online on: 23 April 2015

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Article Open Access

Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways

Wan-Ling Chuang, Chin-Cheng Su, Ping-Yi Lin, Chi-Chen Lin, Yao-Li Chen
Pages: 1677-1684
Published online on: 31 March 2015

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Article Open Access

Apoptosis-inducing factor and calpain upregulation in glutamate-induced injury of rat spiral ganglion neurons

Zhong‑Jia Ding, Xin Chen, Xiao‑Xu Tang, Xi Wang, Yong‑Li Song, Xiao‑Dong Chen, Jian Wang, Ren‑Feng Wang, Wen‑Juan Mi, Fu‑Quan Chen, Jian‑Hua Qiu
Pages: 1685-1692
Published online on: 16 April 2015

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Article Open Access

Upregulation of neuroglobin expression and changes in serum redox indices in a rat model of middle cerebral artery occlusion

Aijia Shang, Ying Yang, Hangyan Wang, Jing Wang, Xingyi Hang, Zhongfeng Wang, Dingbiao Zhou
Pages: 1693-1698
Published online on: 03 April 2015

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Article Open Access

Anti-proliferative effects of qianliening capsules on prostatic hyperplasia in vitro and in vivo

Xiaoyong Zhong, Jiumao Lin, Jianheng Zhou, Wei Xu, Zhenfeng Hong
Pages: 1699-1708
Published online on: 27 March 2015

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Article Open Access

Short‑term vagal nerve stimulation improves left ventricular function following chronic heart failure in rats

Yan Li, Yan‑Hua Xuan, Shuang‑Shuang Liu, Jing Dong, Jia‑Ying Luo, Zhi‑Jun Sun
Pages: 1709-1716
Published online on: 07 April 2015

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Article Open Access

Effectiveness of combined salmon calcitonin and aspirin therapy for osteoporosis in ovariectomized rats

Jinsong Wei, Jian Wang, Yan Gong, Rong Zeng
Pages: 1717-1726
Published online on: 16 April 2015

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Article Open Access

Inhibition of autophagy using 3‑methyladenine increases cisplatin‑induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells

Ruijian Zhang, Ruijun Wang, Qianxue Chen, Hong Chang
Pages: 1727-1732
Published online on: 01 April 2015

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Article Open Access

G‑protein‑coupled receptor 30‑mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms

Jingyu Chen, Rong Hu, Hongfei Ge, Wangsheng Duanmu, Yuhong Li, Xingseng Xue, Shengli Hu, Hua Feng
Pages: 1733-1740
Published online on: 08 April 2015

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Article Open Access

Identification of human leukemia antigen A*0201‑restricted epitopes derived from epidermal growth factor pathway substrate number 8

Baishan Tang, Weijun Zhou, Jingwen Du, Yanjie He, Yuhua Li
Pages: 1741-1752
Published online on: 23 April 2015

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Article Open Access

Effects of mesenchymal stem cells on interleukin-1β-treated chondrocytes and cartilage in a rat osteoarthritic model

Jilei Tang, Weiding Cui, Fanglong Song, Chenjun Zhai, Hansheng Hu, Qiang Zuo, Weimin Fan
Pages: 1753-1760
Published online on: 20 April 2015

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Article Open Access

Leptin modulates the expression of catabolic genes in rat nucleus pulposus cells through the mitogen‑activated protein kinase and Janus kinase 2/signal transducer and activator of transcription 3 pathways

Daoyi Miao, Lingzhou Zhang
Pages: 1761-1768
Published online on: 20 April 2015

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Article Open Access

Deciphering the underlying mechanisms of Diesun Miaofang in traumatic injury from a systems pharmacology perspective

Chun‑Song Zheng, Chang‑Long Fu, Cai‑Bin Pan, Hong‑Juan Bao, Xing‑Qiang Chen, Hong‑Zhi Ye, Jin‑Xia Ye, Guang‑Wen Wu, Xi‑Hai Li, Hui‑Feng Xu, Xiao‑Jie Xu, Xian‑Xiang Liu
Pages: 1769-1776
Published online on: 16 April 2015

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Article Open Access

Anti-tumoral effects of a trypsin inhibitor derived from buckwheat in vitro and in vivo

Chong‑Zhi Bai, Ma‑Li Feng, Xu‑Liang Hao, Zhi‑Juan Zhao, Yu‑Ying Li, Zhuan‑Hua Wang
Pages: 1777-1782
Published online on: 20 April 2015

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Article Open Access

Effect of the WWOX gene on the regulation of the cell cycle and apoptosis in human ovarian cancer stem cells

Hongchao Yan, Jianye Tong, Xiaoman Lin, Qiuyu Han, Hongxiang Huang
Pages: 1783-1788
Published online on: 17 April 2015

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Article Open Access

Identification of therapeutic targets for breast cancer using biological informatics methods

Xuejian Liu, Yongzhen Ma, Wenchuan Yang, Xia Wu, Lihua Jiang, Xiangli Chen
Pages: 1789-1795
Published online on: 27 March 2015

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Article Open Access

Ulinastatin inhibits cerebral ischemia-induced apoptosis in the hippocampus of gerbils

Young‑Sam Cho, Mal‑Soon Shin, Il‑Gyu Ko, Sung‑Eun Kim, Chang‑Ju Kim, Yun‑Hee Sung, Hye‑Sun Yoon, Bong‑Jae Lee
Pages: 1796-1802
Published online on: 15 April 2015

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Article Open Access

Role of phosphorylated extracellular signal-regulated kinase, calcitonin gene-related peptide and cyclooxygenase-2 in experimental rat models of migraine

Xiaomeng Dong, Yaozhi Hu, Long Jing, Jinbo Chen
Pages: 1803-1809
Published online on: 15 April 2015

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Article Open Access

Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells

Jin‑Hang Wang, Wen‑Wen Zhou, Shi‑Tong Cheng, Bo‑Xin Liu, Fu‑Rong Liu, Jian‑Qing Song
Pages: 1810-1816
Published online on: 30 March 2015

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Article Open Access

Meteorin is upregulated in reactive astrocytes and functions as a negative feedback effector in reactive gliosis

Hye Shin Lee, Soon‑Hee Lee, Jong‑Ho Cha, Ji Hae Seo, Bum Ju Ahn, Kyu‑Won Kim
Pages: 1817-1823
Published online on: 14 April 2015

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Article Open Access

Identification of the proliferative effect of Smad2 and 3 in the TGF β2/Smad signaling pathway using RNA interference in a glioma cell line

Chengyuan Dong, Ruifang Mi, Guishan Jin, Yiqiang Zhou, Jin Zhang, Fusheng Liu
Pages: 1824-1828
Published online on: 15 April 2015

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Article Open Access

Effect of β-anhydroicaritin on the expression levels of tumor necrosis factor-α and matrix metalloproteinase-3 in periodontal tissue of diabetic rats

Yingtao Wu, Wanchun Wang, Lian Liu
Pages: 1829-1837
Published online on: 02 April 2015

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Article Open Access

Recombinant lentivirus with enhanced expression of caudal‑related homeobox protein 2 inhibits human colorectal cancer cell proliferation in vitro

Sai He, Xue‑Jun Sun, Jian‑Bao Zheng, Jie Qi, Nan‑Zheng Chen, Wei Wang, Guang‑Bing Wei, Dong Liu, Jun‑Hui Yu, Shao‑Ying Lu, Hui Wang
Pages: 1838-1844
Published online on: 03 April 2015

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Article Open Access

Identification of two novel Darier disease‑associated mutations in the ATP2A2 gene

Libao Zheng, Huili Jiang, Qin Mei, Bin Chen
Pages: 1845-1849
Published online on: 09 April 2015

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Article Open Access

Epigallocatechin‑3‑gallate and zinc provide anti‑apoptotic protection against hypoxia/reoxygenation injury in H9c2 rat cardiac myoblast cells

Xing Zeng, Xuerui Tan
Pages: 1850-1856
Published online on: 08 April 2015

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Article Open Access

mRNA and microRNA expression profiles of radioresistant NCI‑H520 non‑small cell lung cancer cells

Wei Guo, Li Xie, Long Zhao, Yuehuan Zhao
Pages: 1857-1867
Published online on: 08 April 2015

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Article Open Access

PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells

Ze‑Tan Chen, Wei Zhao, Song Qu, Ling Li, Xiao-Di Lu, Fang Su, Zhong-Guo Liang, Si-Yan Guo, Xiao-Dong Zhu
Pages: 1868-1876
Published online on: 09 April 2015

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Article Open Access

Peroxisome proliferator‑activated receptor‑γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus

Yong‑Zhi San, Yu Liu, Yu Zhang, Ping‑Ping Shi, Yu‑Lan Zhu
Pages: 1877-1883
Published online on: 17 April 2015

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Article Open Access

Analysis of gene expression profiles associated with glioma progression

Guozhang Hu, Bo Wei, Lina Wang, Le Wang, Daliang Kong, Ying Jin, Zhigang Sun
Pages: 1884-1890
Published online on: 01 April 2015

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Article Open Access

Triptolide ameliorates colonic fibrosis in an experimental rat model

Qingsong Tao, Baochai Wang, Yu Zheng, Guanwei Li, Jianan Ren
Pages: 1891-1897
Published online on: 01 April 2015

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Article Open Access

Salinomycin enhances doxorubicin-induced cytotoxicity in multidrug resistant MCF-7/MDR human breast cancer cells via decreased efflux of doxorubicin

Kwang‑Youn Kim, Sang‑Hun Kim, Sun‑Nyoung Yu, Suel‑Ki Park, Hyeun‑Deok Choi, Hak‑Sun Yu, Jae‑Hoon Ji, Young‑Kyo Seo, Soon‑Cheol Ahn
Pages: 1898-1904
Published online on: 16 April 2015

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Article

Inhibition of expression of hepatitis C virus 1b genotype core and NS4B genes in HepG2 cells using artificial microRNAs

Xiao‑Hua Jiang, Yu‑Tao Xie, Bo Jiang, Meng‑Ying Tang, Tao Ma, Hua Peng
Pages: 1905-1913
Published online on: 31 March 2015

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Article

Particulate matter 2.5 induces autophagy via inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin kinase signaling pathway in human bronchial epithelial cells

Tie Liu, Bin Wu, Yahong Wang, Huijuan He, Ziying Lin, Jianxin Tan, Lawei Yang, David W. Kamp, Xu Zhou, Jinfeng Tang, Haili Huang, Liangqing Zhang, Liu Bin, Gang Liu
Pages: 1914-1922
Published online on: 31 March 2015

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Article

Role of asymmetric dimethylarginine in rat acute lung injury induced by acute ischemic kidney injury

Tao Ma, Xiaowei Liu, Zhi Liu
Pages: 1923-1928
Published online on: 15 April 2015

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Article

Feasibility and safety of porcine Descemet's membrane as a carrier for generating tissue-engineered corneal endothelium

Yu‑Mei Diao, Jing Hong
Pages: 1929-1934
Published online on: 23 April 2015

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Article

Differential expression of Dickkopf-1 among non-small cell lung cancer cells

Xiao Jun Xiang, Ya Wen Liu, Dian Dian Chen, Shuang Yu
Pages: 1935-1940
Published online on: 21 April 2015

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Article

Regulation of connexin 43 and microRNA expression via β2-adrenoceptor signaling in 1321N1 astrocytoma cells

Mojtaba Khaksarian, Hossein Mostafavi, Masoud Soleimani, Seid Morteza Karimian, Mohammad Hassan Ghahremani, Mohammad Taghee Joghataee, Mohsen Khorashadizadeh, Hadi Aligholi, Fatemeh Attari, Gholamreza Hassanzadeh
Pages: 1941-1950
Published online on: 14 April 2015

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Article

Rho-associated protein kinase inhibitor, Y-27632, significantly enhances cell adhesion and induces a delay in G1 to S phase transition in rabbit corneal endothelial cells

Yu‑Mei Diao, Jing Hong
Pages: 1951-1956
Published online on: 16 April 2015

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Article

Alternatively spliced products lacking exon 12 dominate the expression of fragile X mental retardation 1 gene in human tissues

Xianguo Fu, Dezhu Zheng, Juan Liao, Qingqin Li, Yuxiang Lin, Duo Zhang, Aizhen Yan, Fenghua Lan
Pages: 1957-1962
Published online on: 31 March 2015

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Article

Tribbles homolog 3 is induced by high glucose and associated with apoptosis in human endothelial cells

Ling Guo, Zhong‑Xiu Guo, Hui‑Ping Gong, Yuan‑Yuan Shang, Ming Zhong, Yun Zhang, Wei Zhang
Pages: 1963-1970
Published online on: 31 March 2015

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Article

Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling

Peng Gao, Jingxian Yang, Xi Gao, Dan Xu, Dongge Niu, Jinglin Li, Qingping Wen
Pages: 1971-1976
Published online on: 16 April 2015

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Article

Computational analysis identifies invasion-associated genes in pituitary adenomas

Changjun Cao, Wei Wang, Chao Ma, Pucha Jiang
Pages: 1977-1982
Published online on: 27 March 2015

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Article

Effect of secondary hyperparathyroidism serum on endothelial cells and intervention with Klotho

Cheng Chen, Huijuan Mao, Xiangbo Yu, Bin Sun, Ming Zeng, Xiufen Zhao, Jun Qian, Jia Liu, Changying Xing
Pages: 1983-1990
Published online on: 09 April 2015

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Article

Screening of differentially expressed genes associated with human glioblastoma and functional analysis using a DNA microarray

Lina Wang, Bo Wei, Guozhang Hu, Le Wang, Miaomiao Bi, Zhigang Sun, Ying Jin
Pages: 1991-1996
Published online on: 22 April 2015

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Article

Sasanquasaponin from Camellia oleifera Abel. induces apoptosis via Bcl-2, Bax and caspase-3 activation in HepG2 cells

Jianwei Zeng, Shiqiang Chen, Na Li, Liang Chen, Jiaosu Su, Guangjun Niu, Si Zhu, Yichi Liang
Pages: 1997-2002
Published online on: 23 April 2015

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Article

DJ-1-induced phosphatase and tensin homologue downregulation is associated with proliferative and invasive activity of laryngeal cancer cells

Xiao‑Lin Zhu, Wei Sun, Wen‑Bin Lei, Hui‑Wen Zhuang, Wei‑Jian Hou, Wei‑Ping Wen
Pages: 2003-2008
Published online on: 15 April 2015

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Article

Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis

Yong Cheng, Xuehua Guo, Yiming Gong, Xiaojun Ding, Youcheng Yu
Pages: 2009-2014
Published online on: 22 April 2015

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Article

Single prolonged stress induces dysfunction of endoplasmic reticulum in a rat model of post-traumatic stress disorder

Bing Xiao, Bo Yu, Dong‑Juan Liu, Fang Han, Yu‑Xiu Shi
Pages: 2015-2020
Published online on: 02 April 2015

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Article

Pseudolaric acid B exerts antitumor activity via suppression of the Akt signaling pathway in HeLa cervical cancer cells

Mingqun Li, Li Hong
Pages: 2021-2026
Published online on: 15 April 2015

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Article

Electroacupuncture pretreatment attenuates blood‑brain barrier disruption following cerebral ischemia/reperfusion

Rong Zou, Zhouquan Wu, Suyang Cui
Pages: 2027-2034
Published online on: 23 April 2015

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Article

Matrix metalloproteinase‑mediation of tumor targeting human recombinant tumor necrosis factor‑α fusion protein

Hui Ren, Xin Shao, Liang Zeng, Fa Wang, Di‑Nan Huang, Gan Hou
Pages: 2035-2042
Published online on: 17 April 2015

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Article

Calcium‑sensing receptor is involved in the pathogenesis of fat emulsion‑induced insulin resistance in rats

Jiaming Xie, Yuan Jiang, Yuna Kan, Jing Zhao, Haixue Kuang, Pengling Ge
Pages: 2043-2048
Published online on: 20 April 2015

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Article

Propofol post‑conditioning protects the blood brain barrier by decreasing matrix metalloproteinase‑9 and aquaporin‑4 expression and improves the neurobehavioral outcome in a rat model of focal cerebral ischemia‑reperfusion injury

Feng‑Tao Ji, Jian‑Jun Liang, Li‑Ping Miao, Qiang Wu, Ming‑Hui Cao
Pages: 2049-2055
Published online on: 01 April 2015

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Article

Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma

Xiaobo Wang, Jingxuan Pan, Juan Li
Pages: 2056-2062
Published online on: 22 April 2015

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Article

Knockdown of reticulon 4C by lentivirus inhibits human colorectal cancer cell growth

Hui Xue, Zheng Wang, Jinxian Chen, Zeyu Yang, Jian Tang
Pages: 2063-2067
Published online on: 31 March 2015

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Article

Conditionally replicating oncolytic adenoviral vector expressing arresten and tumor necrosis factor-related apoptosis-inducing ligand experimentally suppresses lung carcinoma progression

Shudong Li, Zongli Qi, Huijin Li, Jun Hu, Dongyang Wang, Xin Wang, Zhenzhen Feng
Pages: 2068-2074
Published online on: 16 April 2015

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Article

Association between the expression of T-cadherin and vascular endothelial growth factor and the prognosis of patients with gastric cancer

Bin Wei, Haitao Shi, Xiaolan Lu, Ameng Shi, Yan Cheng, Lei Dong
Pages: 2075-2081
Published online on: 02 April 2015

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Article

Role of calcium in the regulation of bone morphogenetic protein 2, runt-related transcription factor 2 and Osterix in primary renal tubular epithelial cells by the vitamin D receptor

Zhaohui Jia, Shaogang Wang, Deng He, Lei Cui, Yuchao Lu, Henglong Hu, Baolong Qin, Zhenyu Zhao
Pages: 2082-2088
Published online on: 30 March 2015

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Article

Bone marrow-derived mesenchymal stem cells attenuate acute liver injury and regulate the expression of fibrinogen-like-protein 1 and signal transducer and activator of transcription 3

Zhuolin Zou, Yijing Cai, Yi Chen, Si Chen, Liyuan Liu, Zhonghai Shen, Sainan Zhang, Lanman Xu, Yongping Chen
Pages: 2089-2097
Published online on: 22 April 2015

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Article

Resveratrol prevents osteoporosis in ovariectomized rats by regulating microRNA-338-3p

Da‑Wei Guo, Ya‑Xin Han, Lin Cong, Dong Liang, Guan‑Jun Tu
Pages: 2098-2106
Published online on: 01 April 2015

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Article

Ubiquitin-specific peptidase 22 inhibits colon cancer cell invasion by suppressing the signal transducer and activator of transcription 3/matrix metalloproteinase 9 pathway

Ning Ao, Yanyan Liu, Xiaocui Bian, Hailiang Feng, Yuqin Liu
Pages: 2107-2113
Published online on: 22 April 2015

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Article

Increased expression of neuropilin 1 is associated with epithelial ovarian carcinoma

Haiyan Jiang, Qinghua Xi, Feiran Wang, Zhichao Sun, Zhongwei Huang, Lei Qi
Pages: 2114-2120
Published online on: 01 April 2015

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Article

Hypoxia regulates the expression and localization of CCAAT/enhancer binding protein α by hypoxia inducible factor‑1α in bladder transitional carcinoma cells

Mei Xue, Xu Li, Wei Chen
Pages: 2121-2127
Published online on: 27 March 2015

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Article

CSE/H2S system protects mesenchymal stem cells from hypoxia and serum deprivation‑induced apoptosis via mitochondrial injury, endoplasmic reticulum stress and PI3K/Akt activation pathways

Zeng Guo, Cong Sheng Li, Chun Miao Wang, Yang Jing Xie, Ai Ling Wang
Pages: 2128-2134
Published online on: 20 April 2015

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Article

Effects of Schisandra chinensis Turcz. fruit on contact dermatitis induced by dinitrofluorobenzene in mice

Hee Jung Lee, Suzy Jo, Jeonghyun Ryu, Han‑Sol Jeong, Guemsan Lee, Mi Heon Ryu, Myeong Ho Jung, Hyungwoo Kim, Byung Joo Kim
Pages: 2135-2139
Published online on: 15 April 2015

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Article

Improvement in the blastocyst quality and efficiency of putative embryonic stem cell line derivation from porcine embryos produced in vitro using a novel culturing system

Seung A. Cheong, Eunhye Kim, Seong‑Sung Kwak, Yubyeol Jeon, Sang‑Hwan Hyun
Pages: 2140-2148
Published online on: 16 April 2015

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Article

Neuroprotective effects of brilliant blue G on the brain following traumatic brain injury in rats

Yong‑Chao Wang, Ying Cui, Jian‑Zhong Cui, Li‑Qian Sun, Chang‑Meng Cui, Hong‑Ao Zhang, Hui‑Xing Zhu, Ran Li, Yan‑Xia Tian, Jun‑Ling Gao
Pages: 2149-2154
Published online on: 14 April 2015

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Article

Attenuation of Porphyromonas gingivalis oral infection by α‑amylase and pentamidine

Ying Li, Yu‑Song Miao, Yun Fu, Xi‑Ting Li, Shao‑Jie Yu
Pages: 2155-2160
Published online on: 01 April 2015

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Article

Chelidonine suppresses migration and invasion of MDA-MB-231 cells by inhibiting formation of the integrin-linked kinase/PINCH/α-parvin complex

Okhwa Kim, Cheol Hwangbo, Junhyeong Kim, Dong‑Hao Li, Byung‑Sun Min, Jeong‑Hyung Lee
Pages: 2161-2168
Published online on: 15 April 2015

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Article

Optimized generation of survivin-specific cytotoxic T lymphocytes against lung cancer

Ying Li, Juanjuan Ding
Pages: 2169-2174
Published online on: 01 April 2015

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Article

Pulsed electromagnetic wave exposure induces ultrastructural damage and upregulated expression of heat shock protein 70 in the rat adenohypophysis

Kang Cheng, Dong‑Qing Ren, Jun Yi, Xiao‑Guang Zhou, Wen‑Qing Yang, Yong‑Bin Chen, Yong‑Qiang Li, Xiao‑Feng Huang, Gui‑Ying Zeng
Pages: 2175-2180
Published online on: 16 April 2015

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Article

Exogenous α-calcitonin gene-related peptide attenuates lipopolysaccharide-induced acute lung injury in rats

Wang Yang, Meng Xv, Wan Chao Yang, Nan Wang, Xue Zhong Zhang, Wen Zhi Li
Pages: 2181-2188
Published online on: 15 April 2015

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Article

Exogenous cytochrome c inhibits the expression of transforming growth factor-β1 in a mouse model of sepsis-induced myocardial dysfunction via the SMAD1/5/8 signaling pathway

Yuan‑Zheng Yang, Ting‑Ting Fan, Feng Gao, Juan Fu, Qiong Liu
Pages: 2189-2196
Published online on: 16 April 2015

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Article

Expression, purification and identification of Pla a1 in a codon-optimized Platanus pollen allergen

Yun Liu, Xiuzhen Sun, Guizuo Wang, Ailin Tao, Yuanyuan Wu, Manxiang Li, Hongyang Shi, Mei Xie
Pages: 2197-2202
Published online on: 21 April 2015

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Article

Platelet endothelial cell adhesion molecule‑1 gene 125C/G polymorphism is associated with deep vein thrombosis

Gang Li, Zong‑Lin Han, He‑Gui Dong, Xia Zhang, Xiang‑Qian Kong, Xing Jin
Pages: 2203-2210
Published online on: 01 April 2015

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Article

HOTAIR is a potential target for the treatment of cisplatin‑resistant ovarian cancer

Yu Wang, Hongli Wang, Tiefang Song, Yiting Zou, Jing Jiang, Lei Fang, Peiling Li
Pages: 2211-2216
Published online on: 27 March 2015

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Article

Neurotoxicity of cerebro-spinal fluid from patients with Parkinson's disease on mesencephalic primary cultures as an in vitro model of dopaminergic neurons

Ping Kong, Ben‑Shu Zhang, Ping Lei, Xiao‑Dong Kong, Shi‑Shuang Zhang, Dai Li, Yun Zhang
Pages: 2217-2224
Published online on: 31 March 2015

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Acylglycerol kinase promotes the proliferation and cell cycle progression of oral squamous cell carcinoma

Guijuan Liu, Xingbin Ren, Chunhai Gao, Wei Zhang
Pages: 2225-2230
Published online on: 08 April 2015

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Article

SirT1 and STAT3 protect retinal pigmented epithelium cells against oxidative stress

Langen Li, Wei Wei, Yufeng Zhang, Gerile Tu, Yanmei Zhang, Jia Yang, Yiqiao Xing
Pages: 2231-2238
Published online on: 31 March 2015

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Article

Effect and mechanism of peroxisome proliferator-activated receptor-γ on the drug resistance of the U-87 MG/CDDP human malignant glioma cell line

Shaorong Han, Xiaoyan Lv, Yanming Wang, Hai Gong, Cong Zhang, Anna Tong, Baoyi Zhang, Hui Yao
Pages: 2239-2246
Published online on: 16 April 2015

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Article

Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine

Christian Mayr, Daniel Neureiter, Martin Pichler, Frieder Berr, Andrej Wagner, Tobias Kiesslich, Konrad Namberger
Pages: 2247-2252
Published online on: 01 April 2015

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Article

Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples

Uwe Lendeckel, Carmen Wolke, Hans‑Gert Bernstein, Gerburg Keilhoff
Pages: 2253-2262
Published online on: 17 April 2015

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Article

Simultaneous silencing of β‑catenin and signal transducer and activator of transcription 3 synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells

Xin‑Hong Wang, Ming‑Na Liu, Ping Huang, Jun Xu, Ai‑Yun Liu, Jing Chen, Cheng‑Qian Lv, Rui‑Ling Xu
Pages: 2263-2268
Published online on: 03 April 2015

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Article

Rapid detection of active human cytomegalovirus infection in pregnancy using loop-mediated isothermal amplification

Xiaoli Wang, Xiaoyan Li, Shuhong Hu, Hongmei Qu, Yinghong Zhang, Huijie Ni, Xiaoliang Wang
Pages: 2269-2274
Published online on: 31 March 2015

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Article

Effects of ghrelin, leptin and melatonin on the levels of reactive oxygen species, antioxidant enzyme activity and viability of the HCT 116 human colorectal carcinoma cell line

Rafał Jakub Bułdak, Katarzyna Pilc‑Gumuła, Łukasz Bułdak, Daria Witkowska, Michał Kukla, Renata Polaniak, Krystyna Zwirska‑Korczala
Pages: 2275-2282
Published online on: 07 April 2015

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Article

Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway

Haihong Lv, Tuanjie Che, Xulei Tang, Lijuan Liu, Jianguo Cheng
Pages: 2283-2290
Published online on: 20 April 2015

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Article

Selection of suitable reference genes for reverse transcription‑quantitative polymerase chain reaction analysis of neuronal cells differentiated from bone mesenchymal stem cells

Yu‑Xi He, Yan Zhang, Qiwei Yang, Chenguang Wang, Guanfang Su
Pages: 2291-2300
Published online on: 23 April 2015

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Article

Protective effects of acteoside against X‑ray‑induced damage in human skin fibroblasts

Jianhua Yang, Yao Yan, Huibin Liu, Jianhua Wang, Junping Hu
Pages: 2301-2306
Published online on: 16 April 2015

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Article

Homozygosity analysis in subjects with autistic spectrum disorder

Ahmad Adi, Basma Tawil, Mohammed Aldosari, Jameela Shinwari, Michael Nester, Hisham Aldhalaan, Hussain Alshamrani, Manar Ghannam, Brian Meyer, Nada Al Tassan
Pages: 2307-2312
Published online on: 22 April 2015

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Article

Disulfiram sensitizes pituitary adenoma cells to temozolomide by regulating O6-methylguanine-DNA methyltransferase expression

Yachao Zhao, Zheng Xiao, Wenna Chen, Jinsheng Yang, Tao Li, Bo Fan
Pages: 2313-2322
Published online on: 22 April 2015

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Article

Chloroquine exerts neuroprotection following traumatic brain injury via suppression of inflammation and neuronal autophagic death

Chang‑Meng Cui, Jun‑Ling Gao, Ying Cui, Li‑Qian Sun, Yong‑Chao Wang, Kai‑Jie Wang, Ran Li, Yan‑Xia Tian, Jian‑Zhong Cui
Pages: 2323-2328
Published online on: 15 April 2015

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Article

Effects of diesel exhaust particles on microRNA-21 in human bronchial epithelial cells and potential carcinogenic mechanisms

Fang Zhou, Suli Li, Wenliang Jia, Gang Lv, Chonglin Song, Chunsheng Kang, Qingyu Zhang
Pages: 2329-2335
Published online on: 22 April 2015

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Article

Microencapsulation of recombinant adenovirus within poly-DL-lactide-poly(ethylene glycol) microspheres for enhanced gene transfection efficiency and inhibitory effects on hepatocellular carcinoma cells in vitro

Dong Xia, Li-Bo Feng, Xiao-Long Wu, Guo-Dong Xia, Liang Xu
Pages: 2336-2342
Published online on: 01 April 2015

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Article

Vascularization of repaired limb bone defects using chitosan-β-tricalcium phosphate composite as a tissue engineering bone scaffold

Le Yang, Qinghua Wang, Lihua Peng, Hong Yue, Zhendong Zhang
Pages: 2343-2347
Published online on: 21 April 2015

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Article

Assessment of the embryotoxicity of four Chinese herbal extracts using the embryonic stem cell test

Lin‑Yan Li, Fen‑Fang Cao, Zhi‑Jian Su, Qi‑Hao Zhang, Xiao‑Yong Dai, Xue Xiao, Ya‑Dong Huang, Qing Zheng, Hua Xu
Pages: 2348-2354
Published online on: 07 April 2015

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Article

MicroRNA-320 inhibits cell proliferation in glioma by targeting E2F1

Ji‑Yong Sun, Wei‑Zhong Xiao, Fei Wang, Yong‑Qian Wang, You‑Hou Zhu, Yi‑Fang Wu, Zeng‑Li Miao, Yu‑Chang Lin
Pages: 2355-2359
Published online on: 22 April 2015

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Article

Antitumor and anti‑angiogenic activity of the recombinant human disintegrin domain of A disintegrin and metalloproteinase 15

Ying Hou, Min Chu, Yanfei Cai, Jianyong Lei, Yun Chen, Ruiyu Zhu, Xiaohai Gong, Xin Ma, Jian Jin
Pages: 2360-2366
Published online on: 16 April 2015

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Article

MicroRNA-9 suppresses the sensitivity of CNE2 cells to ultraviolet radiation

Chao‑Pan Zheng, Ling Han, Wei‑Jian Hou, Jun Tang, Yi‑Hui Wen, Ran Fu, Yue‑Jian Wang, Wei‑Ping Wen
Pages: 2367-2373
Published online on: 16 April 2015

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Article

Effects of high-intensity interval versus continuous moderate‑intensity aerobic exercise on apoptosis, oxidative stress and metabolism of the infarcted myocardium in a rat model

Kai Lu, Li Wang, Changying Wang, Yuan Yang, Dayi Hu, Rongjing Ding
Pages: 2374-2382
Published online on: 23 April 2015

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Article

Antitumor activity of polysaccharide extracted from Pleurotus ostreatus mycelia against gastric cancer in vitro and in vivo

Xiang‑Yu Cao, Jian‑Li Liu, Wei Yang, Xiao Hou, Qi‑Jiu Li
Pages: 2383-2389
Published online on: 20 April 2015

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Article

Aberrant methylation of the GCK gene body is associated with the risk of essential hypertension

Rui Fan, Wei‑Jie Wang, Qi-Long Zhong, Shi-Wei Duan, Xu‑Ting Xu, Ling‑Mei Hao, Jing Zhao, Li-Na Zhang
Pages: 2390-2394
Published online on: 16 April 2015

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Article

Downregulation of microRNA‑221 decreases migration and invasion in fibroblast‑like synoviocytes in rheumatoid arthritis

Shuzhong Yang, Yougeng Yang
Pages: 2395-2401
Published online on: 17 April 2015

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Review

Progress on hypoxia-inducible factor-3: Its structure, gene regulation and biological function (Review)

Sheng‑Li Yang, Chao Wu, Zhi‑Fan Xiong, Xiefan Fang
Pages: 2411-2416
Published online on: 27 April 2015

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Article Open Access

Colorectal cancer stem cell and chemoresistant colorectal cancer cell phenotypes and increased sensitivity to Notch pathway inhibitor

Rui Huang, Guiyu Wang, Yanni Song, Qingchao Tang, Qi You, Zheng Liu, Yinggang Chen, Qian Zhang, Jiaying Li, Shan Muhammand, Xishan Wang
Pages: 2417-2424
Published online on: 28 April 2015

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Article Open Access

Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection

Wan‑Li Li, Wei Xiang, Ye Ping
Pages: 2425-2430
Published online on: 24 April 2015

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Article Open Access

Application of mixsep software package: Performance verification of male-mixed DNA analysis

Na Hu, Bin Cong, Tao Gao, Yu Chen, Junyi Shen, Shujin Li, Chunling Ma
Pages: 2431-2442
Published online on: 30 April 2015

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Article Open Access

Enhancement of the antigen‑specific cytotoxic T lymphocyte‑inducing ability in the PMDC11 leukemic plasmacytoid dendritic cell line via lentiviral vector‑mediated transduction of the caTLR4 gene

Minami Iwabuchi, Miwako Narita, Takayoshi Uchiyama, Shunpei Iwaya, Eri Oiwa, Yoshinori Nishizawa, Shigeo Hashimoto, Aude Bonehill, Noriyuki Kasahara, Jun Takizawa, Masuhiro Takahashi
Pages: 2443-2450
Published online on: 24 April 2015

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Article Open Access

Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy

Wei Cheng, Aimudula Ainiwaer, Lei Xiao, Qian Cao, Ge Wu, Ying Yang, Rui Mao, Yongxing Bao
Pages: 2451-2456
Published online on: 04 May 2015

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Article Open Access

Gene expression profiling via bioinformatics analysis reveals biomarkers in laryngeal squamous cell carcinoma

Guo‑Fang Guan, Ying Zheng, Lian‑Ji Wen, De‑Jun Zhang, Duo‑Jiao Yu, Yan‑Qing Lu, Yan Zhao, Hui Zhang
Pages: 2457-2464
Published online on: 29 April 2015

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Article Open Access

Regulation of gene expression in rats with spinal cord injury based on microarray data

Guoqiang Chen, Xiutong Fang, Meng Yu
Pages: 2465-2472
Published online on: 23 April 2015

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Article Open Access

Protective effect of enterovirus‑71 (EV71) virus‑like particle vaccine against lethal EV71 infection in a neonatal mouse model

Lei Cao, Fengfeng Mao, Zheng Pang, Yao Yi, Feng Qiu, Ruiguang Tian, Qingling Meng, Zhiyuan Jia, Shengli Bi
Pages: 2473-2480
Published online on: 24 April 2015

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Article Open Access

Anti-oxidant effect of heme oxygenase-1 on cigarette smoke-induced vascular injury

Genhuan Yang, Yanchuan Li, Wei Wu, Bao Liu, Leng Ni, Zhanqi Wang, Shiying Miao, Linfang Wang, Changwei Liu
Pages: 2481-2486
Published online on: 04 May 2015

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Article Open Access

Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer

Jing Chen, Chundong Zhang, Xiaoyang Xu, Xinjiang Zhu, Dongqiu Dai
Pages: 2487-2494
Published online on: 23 April 2015

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Article Open Access

Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury

Hongwei Liu, Ning Hua, Keliang Xie, Tingting Zhao, Yonghao Yu
Pages: 2495-2502
Published online on: 05 May 2015

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Article Open Access

Involvement of enhancer of zeste homolog 2 in cisplatin‑resistance in ovarian cancer cells by interacting with several genes

Huali Wang, Yunhai Yu, Chen Chen, Qian Wang, Taisheng Huang, Fangzhen Hong, Lin Zhu
Pages: 2503-2510
Published online on: 07 May 2015

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Article Open Access

Mesenchymal stem cells abrogate experimental asthma by altering dendritic cell function

Shao‑Lin Zeng, Li‑Hui Wang, Ping Li, Wei Wang, Jiong Yang
Pages: 2511-2520
Published online on: 30 April 2015

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Article Open Access

Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein

Yu Sen Hou, Ling Ying Liu, Jia Ke Chai, Yong Hui Yu, Hong Jie Duan, Quan Hu, Hui Nan Yin, Yi He Wang, Shu Bo Zhuang, Jun Fan, Wan Li Chu, Li Ma
Pages: 2521-2528
Published online on: 04 May 2015

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Single nucleotide polymorphisms in premature ovarian failure‑associated genes in a Chinese Hui population

Lili Ma, Yan Chen, Si Mei, Chunlian Liu, Xiaohong Ma, Yongli Li, Yinzhi Jiang, Lingxia Ha, Xian Xu
Pages: 2529-2538
Published online on: 08 May 2015

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Association analysis of polymorphisms of the CRHR1 gene with infantile spasms

Guang Yang, Li-Ping Zou, Jing Wang, Xiu-Yu Shi, Xiao-Fan Yang, Bin Wang, Yu-Jie Liu, Yan-Hong Sun, Fei-Yong Jia
Pages: 2539-2546
Published online on: 07 May 2015

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Hypoglycemic effects of aqueous persimmon leaf extract in a murine model of diabetes

Ui‑Jin Bae, Soo‑Hyun Park, Su‑Young Jung, Byung‑Hyun Park, Soo‑Wan Chae
Pages: 2547-2554
Published online on: 08 May 2015

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Differences in the protein expression levels of Trx2 and Prx3 in the hippocampal CA1 region between adult and aged gerbils following transient global cerebral ischemia

Choong Hyun Lee, Joon Ha Park, Jeong‑Hwi Cho, Ji Hyeon Ahn, Eun Joo Bae, Moo‑Ho Won
Pages: 2555-2562
Published online on: 08 May 2015

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A novel intracerebral hemorrhage-induced rat model of neurogenic voiding dysfunction: Analysis of lower urinary tract function

Young‑Sam Cho, Il-Gyu Ko, Chang-Ju Kim, Khae‑Hawn Kim
Pages: 2563-2569
Published online on: 04 May 2015

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Identification of key transcription factors in caerulein‑induced pancreatitis through expression profiling data

Dachuan Qi, Bo Wu, Danian Tong, Ye Pan, Wei Chen
Pages: 2570-2576
Published online on: 12 May 2015

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Impact of immunosuppressive agents on the expression of indoleamine 2,3-dioxygenase, heme oxygenase-1 and interleukin-7 in mesangial cells

Guo‑Biao Liang, Guang‑Heng Luo, Ding‑Su Bao, An‑Jian Chen, Yong‑Xiang Zhuang, Ya‑Nan Guo, Xin Wang, Yuan‑Liang Wang, Zong‑Ping Chen, Yi‑Ping Lu, You‑Ping Li
Pages: 2577-2583
Published online on: 04 May 2015

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Article Open Access

Two novel mutations in the bestrophin-1 gene and associated clinical observations in patients with best vitelliform macular dystrophy

Ying Lin, Hongbin Gao, Yuhua Liu, Xuanwei Liang, Xialin Liu, Zhonghao Wang, Wanjun Zhang, Jiangna Chen, Zhuoling Lin, Xinhua Huang, Yizhi Liu
Pages: 2584-2588
Published online on: 30 April 2015

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Apolipoprotein E deficiency and high‑fat diet cooperate to trigger lipidosis and inflammation in the lung via the toll-like receptor 4 pathway

Qiufang Ouyang, Ziyang Huang, Huili Lin, Jingqin Ni, Huixia Lu, Xiaoqing Chen, Zhenhua Wang, Ling Lin
Pages: 2589-2597
Published online on: 12 May 2015

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A cortical astrocyte subpopulation inhibits axon growth in vitro and in vivo

Rui Liu, Zhe Wang, Lin Gou, Hanpeng Xu
Pages: 2598-2606
Published online on: 29 April 2015

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Exogenous Nkx2.5‑ or GATA‑4‑transfected rabbit bone marrow mesenchymal stem cells and myocardial cell co‑culture on the treatment of myocardial infarction in rabbits

Pu Li, Lei Zhang
Pages: 2607-2621
Published online on: 12 May 2015

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Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway

Jun Chen, He Zhu, Yan Zhang, Man‑Hua Cui, Li‑Ying Han, Zhan‑Hui Jia, Ling Wang, Hong Teng, Li‑Ning Miao
Pages: 2622-2628
Published online on: 07 May 2015

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Comparison of the proliferation, cytotoxic activity and cytokine secretion function of cascade primed immune cells and cytokine‑induced killer cells in vitro

Gui‑Xin Li, Shu‑Shu Zhao, Xu‑Guang Zhang, Wen‑Hao Wang, Jin Liu, Ke‑Wei Xue, Xiao‑Yan Li, Ying‑Xue Guo, Li‑Hua Wang
Pages: 2629-2635
Published online on: 08 May 2015

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Expression of tumor necrosis factor α-induced protein 8 is upregulated in human gastric cancer and regulates cell proliferation, invasion and migration

Yansen Li, Changqing Jing, Yuezhi Chen, Jinshen Wang, Mingliang Zhou, Xin Liu, Dong Sun, Linjun Mu, Leping Li, Xiaobo Guo
Pages: 2636-2642
Published online on: 27 April 2015

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Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation

Xiaoshuang Zhou, Chen Wang, Jihua Tian, Yanhong Wang, Yafeng Li, Zhaoyong Hu, Rongshan Li
Pages: 2643-2649
Published online on: 04 May 2015

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Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells

Kyung Mi Lim, Sungkwan An, Ok‑Kyu Lee, Myung Joo Lee, Jeong Pyo Lee, Kwang Sik Lee, Ghang Tai Lee, Kun Kook Lee, Seunghee Bae
Pages: 2650-2660
Published online on: 04 May 2015

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Inhibiting histone deacetylase 6 partly protects cultured rat cortical neurons from oxygen‑glucose deprivation‑induced necroptosis

Liming Yuan, Zhen Wang, Lihua Liu, Xiaohong Jian
Pages: 2661-2667
Published online on: 13 May 2015

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Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma

Jing Lu, Yabin Cheng, Guohong Zhang, Yun Tang, Ziming Dong, Kevin J. McElwee, Gang Li
Pages: 2668-2676
Published online on: 07 May 2015

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Article

Minocycline attenuates pain by inhibiting spinal microglia activation in diabetic rats

Jin‑Shan Sun, Yu‑Jie Yang, Yong‑Zhen Zhang, Wen Huang, Zhao‑Shen Li, Yong Zhang
Pages: 2677-2682
Published online on: 06 May 2015

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Article

Role of α‑synuclein in cognitive dysfunction: Studies in Drosophila melanogaster

Xiaofeng Zhao, Xicui Sun, Song Cai, Dongzhi Ran, Ying Yan, Zhong Pei
Pages: 2683-2688
Published online on: 08 May 2015

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Article

Rhubarb extract has a protective role against radiation-induced brain injury and neuronal cell apoptosis

Kui Lu, Cheng Zhang, Wenjun Wu, Min Zhou, Yamei Tang, Ying Peng
Pages: 2689-2694
Published online on: 28 April 2015

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Article

Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis

Di‑Fei Wang, Hui‑Jing Yang, Jian‑Qiu Gu, Yan‑Li Cao, Xin Meng, Xiao‑Li Wang, Yi‑Chen Lin, Ming Gao
Pages: 2695-2700
Published online on: 12 May 2015

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Article

Suppression of microRNA-18a expression inhibits invasion and promotes apoptosis of human trophoblast cells by targeting the estrogen receptor α gene

Xiaoming Zhu, Yang Yang, Tao Han, Guowu Yin, Ping Gao, Yunfeng Ni, Xiaohua Su, Yuying Liu, Yuanqing Yao
Pages: 2701-2706
Published online on: 04 May 2015

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Article

A comprehensive analysis of differentially expressed genes and pathways in abdominal aortic aneurysm

Kai Yuan, Wei Liang, Jiwei Zhang
Pages: 2707-2714
Published online on: 30 April 2015

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Article

High and fluctuating glucose levels increase the expression and secretion of interleukin‑18 in mouse peritoneal macrophages

Chenchen Zhang, Yaxin Bi, Guoxi Jin, Huaiyong Gan, Lei Yu
Pages: 2715-2720
Published online on: 07 May 2015

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Article

MicroRNA-135b exerts oncogenic activity in glioblastoma via the inhibition of glycerol kinase 5 expression

Yong Yu, Jian‑Hua Zhang, Bao‑Zhong Zhang
Pages: 2721-2726
Published online on: 30 April 2015

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Article

Long-term expression of metabolism-associated genes in the rat hippocampus following recurrent neonatal seizures and its regulation by melatonin

Hong Ni, Qi Sun, Tian Tian, Xing Feng, Bao‑Liang Sun
Pages: 2727-2734
Published online on: 28 April 2015

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Article

Paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulation

Weihua Li, Zhonghua Qi, Zhenqing Wei, Siwei Liu, Pin Wang, Yanwei Chen, Yongshun Zhao
Pages: 2735-2740
Published online on: 04 May 2015

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Article

Identification of lymphatic metastasis‑associated genes in a metastatic ovarian cancer cell line

Yu Kang, Tao Pu, Qingqing Cai, Shanshan Hong, Mingxing Zhang, Guiling Li, Zhiling Zhu, Congjian Xu
Pages: 2741-2748
Published online on: 07 May 2015

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Article

Quinolone-indolone conjugate induces apoptosis by inhibiting the EGFR-STAT3-HK2 pathway in human cancer cells

Ying‑Hua Liu, Xiao-Li Wei, Guo‑Qiang Hu, Tian‑Xiao Wang
Pages: 2749-2756
Published online on: 04 May 2015

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Article

Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases

Toru Ishibashi, Miki Ichikawa, Bunpei Sato, Shinji Shibata, Yuichi Hara, Yuji Naritomi, Ken Okazaki, Yasuharu Nakashima, Yukihide Iwamoto, Samon Koyanagi, Hiroshi Hara, Tetsuhiko Nagao
Pages: 2757-2764
Published online on: 30 April 2015

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Article

Inhibiting Notch‑1 reduces the expression of Toll‑like receptor 9 in BABL/C‑lpr mouse kidneys and improves glucocorticoid sensitivity

Gong Xiao, Wangbin Ning, Chunhu Zhang, Shiyao Wu, Xiaoxia Zuo
Pages: 2765-2770
Published online on: 08 May 2015

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Article

Aβ peptide secretion is reduced by Radix Polygalae‑induced autophagy via activation of the AMPK/mTOR pathway

Huan Zhao, Zhi‑Cheng Wang, Kui‑Feng Wang, Xiao‑Yu Chen
Pages: 2771-2776
Published online on: 13 May 2015

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Article

Anti‑angiogenic effects of resveratrol in combination with 5‑fluorouracil on B16 murine melanoma cells

Sol Hwa Lee, Bong Seong Koo, Song Yi Park, Young Min Kim
Pages: 2777-2783
Published online on: 24 April 2015

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Article

Number and distribution of myofibroblasts and α-smooth muscle actin expression levels in fetal membranes with and without gestational complications

Xiaoyan Ma, Fan Yang, Shuli Yang, Azhar Rasul, Ting Li, Lianlian Liu, Min Kong, Dongmei Guo, Tonghui Ma
Pages: 2784-2792
Published online on: 04 May 2015

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Article

Brain‑derived neurotrophic factor is a novel target gene of the hsa‑miR‑183/96/182 cluster in retinal pigment epithelial cells following visible light exposure

Hongyang Li, Yan Gong, Haiyan Qian, Tingjun Chen, Zihao Liu, Zhaocai Jiang, Shihui Wei
Pages: 2793-2799
Published online on: 06 May 2015

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Article

Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway

Zhiyun Cao, Xuzheng Chen, Wei Lin, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Lianming Liao, Jian Du
Pages: 2800-2806
Published online on: 28 April 2015

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Article

Pachymic acid protects H9c2 cardiomyocytes from lipopolysaccharide-induced inflammation and apoptosis by inhibiting the extracellular signal-regulated kinase 1/2 and p38 pathways

Fang‑Fang Li, Yuan Yuan, Yuan Liu, Qing‑Qing Wu, Rong Jiao, Zheng Yang, Meng‑Qiao Zhou, Qi‑Zhu Tang
Pages: 2807-2813
Published online on: 30 April 2015

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Article

Protective effect of 2‑deoxy‑D‑glucose on the cytotoxicity of cyclosporin A in vitro

Zizhang Ouyang, Weiwei Cao, Shaohua Zhu, Xiaoping Liu, Zhihua Zhong, Xiangmao Lai, Chengyin Xiao, Sheng Jiang, Yan Wang
Pages: 2814-2820
Published online on: 13 May 2015

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Article

γ‑secretase inhibitor inhibits bladder cancer cell drug resistance and invasion by reducing epithelial‑mesenchymal transition

Yibing Wang, Gongxian Wang, Xiali Zhang, Xiaocheng Zhou, Zhihuan Liu, Liang Huang, Rensheng Liu, Bin Lang, Xiaoyuan Xu, Weipeng Liu, Longlong Fu, Bin Fu
Pages: 2821-2827
Published online on: 07 May 2015

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Article

Combination of the multipotent mesenchymal stromal cell transplantation with administration of temozolomide increases survival of rats with experimental glioblastoma

Igor Bryukhovetskiy, Andrei Bryukhovetsky, Yuri Khotimchenko, Polina Mischenko, Elena Tolok, Rodion Khotimchenko
Pages: 2828-2834
Published online on: 07 May 2015

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Article

Ultrasound-targeted microbubble destruction enhances polyethylenimine-mediated gene transfection in vitro in human retinal pigment epithelial cells and in vivo in rat retina

Caifeng Wan, Jin Qian, Fenghua Li, Hongli Li
Pages: 2835-2841
Published online on: 29 April 2015

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Article

Potassium aspartate inhibits SH‑SY5Y cell damage and apoptosis induced by ouabain and H2O2

Xuefei Sun, Dongyu Min, Yan Wang, Liying Hao
Pages: 2842-2848
Published online on: 07 May 2015

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Article

Identification of microRNAome in rat bladder reveals miR-1949 as a potential inducer of bladder cancer following spinal cord injury

Tianyi Wang, Yong Liu, Wenqi Yuan, Liang Zhang, Yanjun Zhang, Zhijie Wang, Xianhu Zhou, Hengxing Zhou, Tianci Chu, Yan Hao, Bin Liu, Xuechao Zhao, Lu Lu, Shiqing Feng, Xiaohong Kong
Pages: 2849-2857
Published online on: 12 May 2015

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Article

Expression profile of plasma microRNAs in premature infants with respiratory distress syndrome

Qing Kan, Sufang Ding, Yang Yang, Xiaoyu Zhou
Pages: 2858-2864
Published online on: 29 April 2015

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Article

Transcription factor regulatory network for early lung immune response to tuberculosis in mice

Moein Yaqubi, Abdulshakour Mohammadnia, Hossein Fallahi
Pages: 2865-2871
Published online on: 04 May 2015

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Article

5-azacytidine promotes terminal differentiation of hepatic progenitor cells

Yun He, Jiejie Cui, Tongchuan He, Yang Bi
Pages: 2872-2878
Published online on: 12 May 2015

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Article

A hyposensitive anticancer drug induces higher surface expression and release of heat shock proteins in a human hepatocellular carcinoma cell line

Mei Yang, Zhe Xu, Qi Wang, An‑Qin Zhang, Jun Min
Pages: 2879-2885
Published online on: 05 May 2015

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Article

Calponin‑h2 is upregulated in the tissues and plasma of patients with breast cancer

Tianxing Ji, Feifei Ma, Leijun Huo, Xuguang Guo, Bo Chen, Qiang Zhou
Pages: 2886-2892
Published online on: 13 May 2015

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Article

NF‑κB upregulates ubiquitin C‑terminal hydrolase 1 in diseased podocytes in glomerulonephritis

Hongxia Zhang, Xing Mao, Yu Sun, Ruimin Hu, Weili Luo, Zhonghua Zhao, Qi Chen, Zhigang Zhang
Pages: 2893-2901
Published online on: 13 May 2015

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Article

Selective spleen tyrosine kinase inhibition delays autoimmune arthritis in mice

Zuofu Zhang, Chunni Cao, Shui Sun, Qiang Xu
Pages: 2902-2906
Published online on: 08 May 2015

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Article

Role of ROCK expression in gallbladder smooth muscle contraction

Bin Wang, You‑Ming Ding, Chun‑Tao Wang, Wei‑Xing Wang
Pages: 2907-2911
Published online on: 04 May 2015

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Article

Cadmium‑induced autophagy promotes survival of rat cerebral cortical neurons by activating class III phosphoinositide 3‑kinase/beclin‑1/B‑cell lymphoma 2 signaling pathways

Qi‑Wen Wang, Yi Wang, Tao Wang, Kang‑Bao Zhang, Cheng‑Yang Jiang, Fei‑Fei Hu, Yan Yuan, Jian‑Chun Bian, Xue‑Zhong Liu, Jian‑Hong Gu, Zong‑Ping Liu
Pages: 2912-2918
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Article

Upregulation of GRIM‑19 inhibits the growth and invasion of human breast cancer cells Retraction in /10.3892/mmr.2021.12225

Wei Zhang, Ye Du, Tong Jiang, Wei Geng, Jiuli Yuan, Duo Zhang
Pages: 2919-2925
Published online on: 07 May 2015

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Article

Secreted protein acidic and rich in cysteine antagonizes bufalin‑induced apoptosis in gastric cancer cells

Aodi Li, Xiujuan Qu, Zhi Li, Jinglei Qu, Na Song, Yanju Ma, Yunpeng Liu
Pages: 2926-2932
Published online on: 24 April 2015

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Article

Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy

Alexandra C. Kölbl, Roman A. Hiller, Mathias Ilmer, Friederike Liesche, Sabine Heublein, Lennard Schröder, Stefan Hutter, Klaus Friese, Udo Jeschke, Ulrich Andergassen
Pages: 2933-2938
Published online on: 05 May 2015

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Article

A method for establishing human primary gastric epithelial cell culture from fresh surgical gastric tissues

Faisal Aziz, Xuesong Yang, Qingping Wen, Qiu Yan
Pages: 2939-2944
Published online on: 28 April 2015

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Article

Iptakalim attenuates hypoxia-induced pulmonary arterial hypertension in rats by endothelial function protection

Rong Zhu, Li‑Qing Bi, Su‑Ling Wu, Lan Li, Hui Kong, Wei-Ping Xie, Hong Wang, Zi-Li Meng
Pages: 2945-2952
Published online on: 28 April 2015

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Article

Differential hippocampal protein expression between normal aged rats and aged rats with postoperative cognitive dysfunction: A proteomic analysis

Yang Li, Saiying Wang, Ke Ran, Zhonghua Hu, Zhaoqian Liu, Kaiming Duan
Pages: 2953-2960
Published online on: 28 April 2015

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Article

Validation of suitable reference genes for quantitative polymerase chain reaction analysis in rabbit bone marrow mesenchymal stem cell differentiation

Hecheng Ma, Qiwei Yang, Dongsong Li, Jianguo Liu
Pages: 2961-2968
Published online on: 12 May 2015

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Article

Characteristics of dendroaspis natriuretic peptide and its receptor in streptozotocin‑induced diabetic rats

Byoung Hyun Park, Sun Young Kim, Soo Mi Kim, Hye Jung Noh, Chong Gu Cho, Sung Zoo Kim
Pages: 2969-2976
Published online on: 24 April 2015

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Article

Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells

Hye‑Sook Seo, Jin Mo Ku, Han‑Seok Choi, Jong‑Kyu Woo, Bo‑Hyoung Jang, Hoyeon Go, Yong Cheol Shin, Seong‑Gyu Ko
Pages: 2977-2984
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Inflammatory cytokine expression following the use of bipolar electrocoagulation, ultracision harmonic scalpel and cold knife biopsy

Pietro Litta, Carlo Saccardi, Salvatore Gizzo, Lorena Conte, Giulia Ambrosi, Claudia Sissi, Manlio Palumbo
Pages: 2985-2990
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Article

Pre‑ or post‑treatment with ethanol and ethyl pyruvate results in distinct anti‑inflammatory responses of human lung epithelial cells triggered by interleukin‑6

Borna Relja, Nina Omid, Alexander Schaible, Mario Perl, Simon Meier, Elsie Oppermann, Mark Lehnert, Ingo Marzi
Pages: 2991-2998
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Article

N-cadherin, a novel prognostic biomarker, drives malignant progression of colorectal cancer

Xuebing Yan, Leilei Yan, Sihong Liu, Zezhi Shan, Yuan Tian, Zhiming Jin
Pages: 2999-3006
Published online on: 27 April 2015

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Protective effects of extendin‑4 on hypoxia/reoxygenation‑induced injury in H9c2 cells Corrigendum in /10.3892/mmr.2020.11159

Kai Lu, Guanglei Chang, Lin Ye, Peng Zhang, Yong Li, Dongying Zhang
Pages: 3007-3016
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Protective effects of gallic acid against spinal cord injury‑induced oxidative stress

Yong Hong Yang, Zao Wang, Jie Zheng, Ran Wang
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Published online on: 06 May 2015

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Establishment and characterization of triple drug resistant head and neck squamous cell carcinoma cell lines

Sindhu Valiyaveedan Govindan, Safeena Kulsum, Ramanan Somasundara Pandian, Debashish Das, Mukund Seshadri, Wesley Hicks, Moni Abraham Kuriakose, Amritha Suresh
Pages: 3025-3032
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Article

MicroRNA-218, microRNA-191*, microRNA-3070a and microRNA-33 are responsive to mechanical strain exerted on osteoblastic cells

Yong Guo, Yang Wang, Yinqin Liu, Yongming Liu, Qiangcheng Zeng, Yumin Zhao, Xinchang Zhang, Xizheng Zhang
Pages: 3033-3038
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Detection of adenovirus and respiratory syncytial virus in patients with chronic obstructive pulmonary disease: Exacerbation versus stable condition

Nurdan Kokturk, Gulendam Bozdayi, Senay Yilmaz, Bora Doğan, Ozlem Gulbahar, Seyyal Rota, Turkan Tatlicioglu
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Effects of stromal interacting molecule 1 gene silencing by short hairpin RNA on the biological behavior of human gastric cancer cells

Bin Liu, Hai‑Hong Yu, Hong‑Li Ye, Zhi‑Ying Luo, Feng Xiao
Pages: 3047-3054
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Article

Polymorphic variants in the dopamine receptor D2 in women with endometriosis-related infertility

Malgorzata Szczepańska, Adrianna Mostowska, Przemyslaw Wirstlein, Jana Skrzypczak, Matthew Misztal, Paweł P. Jagodziński
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Downregulated microRNA-510-5p acts as a tumor suppressor in renal cell carcinoma

Duqun Chen, Yuchi Li, Zuhu Yu, Yifan Li, Zhengming Su, Liangchao Ni, Shangqi Yang, Yaoting Gui, Yongqing Lai
Pages: 3061-3066
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Two families with Leber's hereditary optic neuropathy carrying G11778A and T14502C mutations with haplogroup H2a2a1 in mitochondrial DNA

Chen Qiao, Tanwei Wei, Bo Hu, Chunyan Peng, Xueping Qiu, Li Wei, Ming Yan
Pages: 3067-3072
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Article

Prime-boost vaccination with Bacillus Calmette Guerin and a recombinant adenovirus co-expressing CFP10, ESAT6, Ag85A and Ag85B of Mycobacterium tuberculosis induces robust antigen-specific immune responses in mice

Wu Li, Min Li, Guangcun Deng, Liping Zhao, Xiaoming Liu, Yujiong Wang
Pages: 3073-3080
Published online on: 12 May 2015

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Article

MicroRNA-29c targets β-site amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo

Guoshuai Yang, Yanmin Song, Xiaoyan Zhou, Yidong Deng, Tao Liu, Guohu Weng, Dan Yu, Suyue Pan
Pages: 3081-3088
Published online on: 05 May 2015

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Article

Decreased mRNA and protein expression of TWIST1 in myocardial tissue of fetuses with ventricular septal defects

Yuting Wang, Qidi Wang, Changlong Guo, Shuo Wang, Yue Qiu, Hui Li, Xu Ma
Pages: 3089-3094
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Article

Inhibiting tumor necrosis factor‑α signaling attenuates postoperative cognitive dysfunction in aged rats

Yuanzhong Ma, Qinghao Cheng, Ermin Wang, Lei Li, Xubin Zhang
Pages: 3095-3100
Published online on: 07 May 2015

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Article

Effect of BML‑111 on the intestinal mucosal barrier in sepsis and its mechanism of action

Huaizheng Liu, Zuoliang Liu, Shangping Zhao, Chuanzheng Sun, Mingshi Yang
Pages: 3101-3106
Published online on: 07 May 2015

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Article

MicroRNA‑137 suppresses tumor growth in epithelial ovarian cancer in vitro and in vivo

Liyu Zhang, Zhihong Li, Fengchun Gai, Yanping Wang
Pages: 3107-3114
Published online on: 07 May 2015

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Article

X609, a novel manassantin A derivative, exhibits antitumor activity in MG-63 human osteosarcoma cells in vitro and in vivo

Ji Li, Kongbo Zhao, Fu Wang, Jinfang Cai, Zongyu Li, Lin Zou
Pages: 3115-3120
Published online on: 05 May 2015

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MicroRNA‑29a inhibits cell migration and invasion by targeting Roundabout 1 in breast cancer cells Retraction in /10.3892/mmr.2023.13151

Hui Li, Jiashun Luo, Bin Xu, Kaijun Luo, Juan Hou
Pages: 3121-3126
Published online on: 07 May 2015

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Article

Quercetin induces the apoptosis of human ovarian carcinoma cells by upregulating the expression of microRNA‑145

Junbo Zhou, Jian Gong, Chun Ding, Guiqin Chen
Pages: 3127-3131
Published online on: 24 April 2015

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Article

Production of recombinant protein G through high-density fermentation of engineered bacteria as well as purification

Hu‑Cheng Zhang, Jun Yang, Guo‑Wei Yang, Xiao‑Jie Wang, Hai‑Tao Fan
Pages: 3132-3138
Published online on: 27 April 2015

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Article

Flavonoids from Triticum aestivum inhibit adipogenesis in 3T3-L1 cells by upregulating the insig pathway

Barun Poudel, Sarmila Nepali, Mingjie Xin, Hyeon‑Hui Ki, Young‑Ho Kim, Dae‑Ki Kim, Young‑Mi Lee
Pages: 3139-3145
Published online on: 29 April 2015

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Article

Circulating microRNA‑122, ‑21 and ‑223 as potential markers of liver injury following warm ischaemia and reperfusion in rats

Patrick Van Caster, Timo Brandenburger, Thorsten Strahl, Sabine Metzger, Inge Bauer, Benedikt Pannen, Sebastian Braun
Pages: 3146-3150
Published online on: 07 May 2015

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Article

Antitumor effect of resveratrol on chondrosarcoma cells via phosphoinositide 3-kinase/AKT and p38 mitogen-activated protein kinase pathways Retraction in /10.3892/mmr.2021.12238

Zixun Dai, Pengfei Lei, Jie Xie, Yihe Hu
Pages: 3151-3155
Published online on: 24 April 2015

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Article

MicroRNA‑216a inhibits the growth and metastasis of oral squamous cell carcinoma by targeting eukaryotic translation initiation factor 4B

Lei Li, Hui‑Qiang Ma
Pages: 3156-3162
Published online on: 08 May 2015

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Article

VEGF‑C inhibition reverses resistance of bladder cancer cells to cisplatin via upregulating maspin

Haipeng Zhu, Feng Yun, Xiaoxue Shi, Dong Wang
Pages: 3163-3169
Published online on: 24 April 2015

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Article

Screening biomarkers of bladder cancer using combined miRNA and mRNA microarray analysis

Ning Jin, Xuefei Jin, Xinquan Gu, Wanli Na, Muchun Zhang, Rui Zhao
Pages: 3170-3176
Published online on: 07 May 2015

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Article

Effect of cell cycle phase on the sensitivity of SAS cells to sonodynamic therapy using low‑intensity ultrasound combined with 5‑aminolevulinic acid in vitro

Nan Li, Miao Sun, Yao Wang, Yanhong Lv, Zheng Hu, Wenwu Cao, Jinhua Zheng, Xiaohui Jiao
Pages: 3177-3183
Published online on: 07 May 2015

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Methylation of the tryptophan hydroxylase‑2 gene is associated with mRNA expression in patients with major depression with suicide attempts

Yuqi Zhang, Zaohuo Chang, Jionghua Chen, Yang Ling, Xiaowei Liu, Zhang Feng, Caixia Chen, Minghua Xia, Xingfu Zhao, Wang Ying, Xu Qing, Guilin Li, Changsong Zhang
Pages: 3184-3190
Published online on: 07 May 2015

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Article

Therapeutic effects of Lactobacillus casei Qian treatment in activated carbon‑induced constipated mice

Xin Zhao, Hua‑Yi Suo, Yu Qian, Gui‑Jie Li, Zhen‑Hu Liu, Jian Li
Pages: 3191-3199
Published online on: 06 May 2015

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Effects of dietary trans‑9 octadecenoic acid, trans‑11 vaccenic acid and cis‑9, trans‑11 conjugated linoleic acid in mice

Tao Wang, Ji‑Na Lim, Jae‑Sung Lee, Sang‑Bum Lee, Jin‑Hee Hwang, U‑Suk Jung, Min‑Jeong Kim, Dae‑Youn Hwang, Sang‑Rak Lee, Sang‑Gun Roh, Hong‑Gu Lee
Pages: 3200-3206
Published online on: 08 May 2015

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Toll-like receptor 2 and -4 are involved in the pathogenesis of the Guillain-Barré syndrome

Yamei Du, Guojun Zhang, Zaiqiang Zhang, Qian Wang, Ruimin Ma, Limin Zhang, Fei Fan, Youran Li, Meng Wang, Hong Lv, Xixiong Kang
Pages: 3207-3213
Published online on: 05 May 2015

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Impact Factor: 3.5

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CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
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Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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