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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2013 Volume 30 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Oncogenic chromosomal translocations and human cancer (Review)

Jie Zheng
Pages: 2011-2019
Published online on: 20 August 2013

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Review

Role of the Hedgehog pathway in hepatocellular carcinoma (Review)

Xin Zheng, Wen Zeng, Xiaohong Gai, Qiuran Xu, Chao Li, Zheyong Liang, Hang Tuo, Qingguang Liu
Pages: 2020-2026
Published online on: 22 August 2013

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Article Open Access

Downregulation of miR-145 contributes to lung adenocarcinoma cell growth to form brain metastases Expression of Concern in /10.3892/or.2025.8991

Chunyang Zhao, Yan Xu, Yongqiang Zhang, Weiwei Tan, Jianxin Xue, Zongze Yang, You Zhang, You Lu, Xun Hu
Pages: 2027-2034
Published online on: 10 September 2013

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Article Open Access

Potential usefulness of mucin immunohistochemical staining of preoperative pancreatic biopsy or juice cytology specimens in the determination of treatment strategies for intraductal papillary mucinous neoplasm

Toru Hisaka, Hiroyuki Horiuchi, Shinji Uchida, Hiroto Ishikawa, Ryuichi Kawahara, Yusuke Kawashima, Masanori Akashi, Kazuhiro Mikagi, Yusuke Ishida, Yoshinobu Okabe, Masamichi Nakayama, Yoshiki Naito, Hirohisa Yano, Tomoki Taira, Akihiko Kawahara, Masayoshi Kage, Hisafumi Kinoshita, Kazuo Shirozu
Pages: 2035-2041
Published online on: 05 September 2013

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Article Open Access

Downregulation of tumstatin expression by overexpression of ornithine decarboxylase

Wei Wang, Chun-Xiao Xu, Guo-Sheng Hou, You-Gen Chen, Jia-Xuan Xin, Xian-Xi Liu
Pages: 2042-2048
Published online on: 29 August 2013

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Article

Effect of occult hepatitis B virus infection on the early-onset of hepatocellular carcinoma in patients with hepatitis C virus infection

Masahito Nakano, Takumi Kawaguchi, Shingo Nakamoto, Atsushi Kawaguchi, Tatsuo Kanda, Fumio Imazeki, Ryoko Kuromatsu, Shuji Sumie, Manabu Satani, Shingo Yamada, Takuji Torimura, Tatsuyuki Kakuma, Osamu Yokosuka, Michio Sata
Pages: 2049-2055
Published online on: 27 August 2013

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Article

Identification of cancer stem cells from hepatocellular carcinoma cell lines and their related microRNAs

Yangmei Xu, Yunqing Xie, Xiangru Wang, Xuefang Chen, Qingyin Liu, Mingang Ying, Qiuhong Zheng
Pages: 2056-2062
Published online on: 28 August 2013

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Article

Ghrelin inhibits ovarian epithelial carcinoma cell proliferation in vitro

Yang Xu, Xiaoyan Pang, Mei Dong, Fang Wen, Yi Zhang
Pages: 2063-2070
Published online on: 23 August 2013

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Article

Enhancement of baicalin by hexamethylene bisacetamide on the induction of apoptosis contributes to simultaneous activation of the intrinsic and extrinsic apoptotic pathways in human leukemia cells

Xia Ren, Yubao Zhang, Cuiling Li, Hengxiao Wang, Zheng Jiang, Zhiyong Zhang, Qiang Guo, Guanhua Song, Kehong Bi, Guosheng Jiang
Pages: 2071-2080
Published online on: 21 August 2013

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Article

APC germline mutations in families with familial adenomatous polyposis

Lillian Barbosa De Queiroz Rossanese, Fernando Augusto De Lima Marson, José Dirceu Ribeiro, Claudio Saddy Rodrigues Coy, Carmen Silvia Bertuzzo
Pages: 2081-2088
Published online on: 21 August 2013

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Article

Epigenetic silencing of KAZALD1 confers a better prognosis and is associated with malignant transformation/progression in glioma

Hongjun Wang, Ying Feng, Zhaoshi Bao, Chuanlu Jiang, Wei Yan, Yongzhi Wang, Chuanbao Zhang, Yanwei Liu, Quangeng Zhang, Wei Zhang
Pages: 2089-2096
Published online on: 29 August 2013

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Article

PINCH expression in relation to radiation response in co-cultured colon cancer cells and in rectal cancer patients

Annica Holmqvist, Birgitta Holmlund, Malin Ardsby, Surajit Pathak, Xiao-Feng Sun
Pages: 2097-2104
Published online on: 20 August 2013

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Article

TFAM is directly regulated by miR-23b in glioma

Jiaode Jiang, Jinfu Yang, Zhifei Wang, Guangyong Wu, Fei Liu
Pages: 2105-2110
Published online on: 30 August 2013

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Article

microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma

Nan Ling, Junyi Gu, Zhe Lei, Mengmeng Li, Jun Zhao, Hong-Tao Zhang, Xiangdong Li
Pages: 2111-2118
Published online on: 22 August 2013

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Article

GRP78 mediates radiation resistance of a stem cell-like subpopulation within the MCF-7 breast cancer cell line

Bo Li, Xiao Liang Cheng, Ye Peng Yang, Zai Quan Li
Pages: 2119-2126
Published online on: 30 August 2013

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Article

Expression of the Arp2/3 complex in human gliomas and its role in the migration and invasion of glioma cells

Zhifeng Liu, Xuejun Yang, Cong Chen, Bin Liu, Bingcheng Ren, Leilei Wang, Kai Zhao, Shengping Yu, Haolang Ming
Pages: 2127-2136
Published online on: 20 August 2013

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Article

BTG1 inhibits breast cancer cell growth through induction of cell cycle arrest and apoptosis

Ran Zhu, Shi-Tao Zou, Jian-Mei Wan, Wei Li, Xin-Li Li, Wei Zhu
Pages: 2137-2144
Published online on: 26 August 2013

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Article

Myocardial protection by interferon-γ late preconditioning during cardiopulmonary bypass‑associated myocardial ischemia-reperfusion in pigs

Xiangang Yan, Wanshan Qiu, Bing Jia, Hui Zhong, Xin Li, Zhanggen Chen
Pages: 2145-2152
Published online on: 29 August 2013

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Article

Diet-induced obesity promotes murine gastric cancer growth through a nampt/sirt1/c-myc positive feedback loop

Hai-Jun Li, Xiang-Ming Che, Wei Zhao, Shi-Cai He, Zheng-Liang Zhang, Rui Chen, Lin Fan, Zong-Liang Jia
Pages: 2153-2160
Published online on: 20 August 2013

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Article

Effects of γ-synuclein on the tumorigenicity and metastasis of colon cancer SW1116 cells in vitro and in vivo

Qing Ye, Feng Huang, Xiao-Ying Wang, Yang-Mei Xu, Fu-Sheng Gong, Li-Jie Huang, Chun-Kang Yang, Qiu-Hong Zheng, Min-Gang Ying
Pages: 2161-2170
Published online on: 22 August 2013

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Article

RNA interference suppression of Nogo-66 receptor prevents Nogo-66-mediated inhibition of invasion and adhesion and simultaneously increases cell apoptosis in C6 cells

Song Tong, Nanxiang Xiong, Jianying Shen
Pages: 2171-2178
Published online on: 26 August 2013

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Article

High levels of EphA3 expression are associated with high invasive capacity and poor overall survival in hepatocellular carcinoma

Cheng-Yi Lu, Zhao-Xu Yang, Liang Zhou, Zhi-Zhong Huang, Hong‑Tao Zhang, Jun Li, Kai-Shan Tao, Bai-Zhi Xie
Pages: 2179-2186
Published online on: 21 August 2013

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Article

Adenovirus-mediated ING4 expression reduces multidrug resistance of human gastric carcinoma cells in vitro and in vivo

Zong-Lei Mao, Song-Bing He, Wei-Hua Sheng, Xiao-Qiang Dong, Ji-Cheng Yang
Pages: 2187-2194
Published online on: 20 August 2013

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Article

Forced downregulation of RACK1 inhibits glioma development by suppressing Src/Akt signaling activity

Renjun Peng, Bing Jiang, Jianrong Ma, Zhiming Ma, Xin Wan, Hongwei Liu, Zigui Chen, Quan Cheng, Rui Chen
Pages: 2195-2202
Published online on: 06 September 2013

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Article

microRNA-200a is an independent prognostic factor of hepatocellular carcinoma and induces cell cycle arrest by targeting CDK6

Fenqiang Xiao, Wu Zhang, Lin Zhou, Haiyang Xie, Chunyang Xing, Songming Ding, Kangjie Chen, Shusen Zheng
Pages: 2203-2210
Published online on: 04 September 2013

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Article

Regulation of differentiation in trabecular bone‑derived mesenchymal stem cells by T cell activation and inflammation

Xinghuo Wu, Wenjuan Wang, Chunqing Meng, Shuhua Yang, Deyu Duan, Weihua Xu, Xianzhe Liu, Ming Tang, Hong Wang
Pages: 2211-2219
Published online on: 22 August 2013

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Article

Methylation of nucleolar and coiled-body phosphoprotein 1 is associated with the mechanism of tumorigenesis in hepatocellular carcinoma

Xuefei Duan, Jinqian Zhang, Shunai Liu, Mengran Zhang, Qi Wang, Jun Cheng
Pages: 2220-2228
Published online on: 20 August 2013

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Article

Proteomic identification of target proteins following Drosha knockdown in cervical cancer

Jun Zhou, Jing Cai, Zaiju Huang, Hui Ding, Junjie Wang, Jinghui Jia, Yong Zhao, Da Huang, Zehua Wang
Pages: 2229-2237
Published online on: 20 August 2013

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Article

Overexpression of CENP-H as a novel prognostic biomarker for human hepatocellular carcinoma progression and patient survival

Guifang Lu, Tao Shan, Shuixiang He, Mudan Ren, Meng Zhu, Yannan Hu, Xinlan Lu, Dan Zhang
Pages: 2238-2244
Published online on: 20 August 2013

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Article

Senescence-associated protein p400 is a prognostic marker in renal cell carcinoma

Stephan Macher-Goeppinger, Justo Lorenzo Bermejo, Peter Schirmacher, Sascha Pahernik, Markus Hohenfellner, Wilfried Roth
Pages: 2245-2253
Published online on: 26 August 2013

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Article

Endoplasmic reticulum protein GliPR1 regulates G protein signaling and the cell cycle and is overexpressed in AML

Gianni Capalbo, Thea Mueller-Kuller, Steffen Koschmieder, Hans-Ulrich Klein, Oliver G. Ottmann, Dieter Hoelzer, Urban J. Scheuring
Pages: 2254-2262
Published online on: 04 September 2013

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Article

microRNA-223 promotes the growth and invasion of glioblastoma cells by targeting tumor suppressor PAX6

Bai-Sheng Huang, Qi-Zhi Luo, Yang Han, Xiao-Bo Li, Li-Jun Cao, Li-Xiang Wu
Pages: 2263-2269
Published online on: 21 August 2013

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Article

Promoter methylation status of the FHIT gene and Fhit expression: Association with HER2/neu status in breast cancer patients

Young Ju Jeong, Hye Yeon Jeong, Sang Min Lee, Jin  Gu Bong, Sung Hwan Park, Hoon Kyu Oh
Pages: 2270-2278
Published online on: 20 August 2013

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Article

Overexpression of heparanase in ovarian cancer and its clinical significance

Wei Zhang, Hong Chan, Louwei Wei, Zhongmian Pan, Jieqing Zhang, Li Li
Pages: 2279-2287
Published online on: 27 August 2013

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Article

Adenovirus-mediated IL-24 expression enhances the chemosensitivity of multidrug-resistantgastric cancer cells to cisplatin

Zonglei Mao, Guochun Bian, Weihua Sheng, Songbin He, Jicheng Yang, Xiaoqiang Dong
Pages: 2288-2296
Published online on: 26 August 2013

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Article

Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma

Pengfei Ren, Hua Ye, Liping Dai, Mei Liu, Xinxin Liu, Yurong Chai, Qing Shao, Yang Li, Ningjing Lei, Bo Peng, Wu Yao, Jianying Zhang
Pages: 2297-2303
Published online on: 04 September 2013

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Article

Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells

King-Chuen Wu, Su-Tso Yang, Shu-Chun Hsu, Jo-Hua Chiang, Te-Chun Hsia, Jai-Sing Yang, Kuo-Ching Liu, Rick Sai-Chuen Wu, Jing-Gung Chung
Pages: 2304-2310
Published online on: 05 September 2013

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Article

Direct sequencing and amplification refractory mutation system for epidermal growth factor receptor mutations in patients with non-small cell lung cancer

Huili Chu, Chen Zhong, Guoliang Xue, Xiuju Liang, Jun Wang, Yingxin Liu, Shiwei Zhao, Qian Zhou, Jingwang Bi
Pages: 2311-2315
Published online on: 29 August 2013

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Article

Cytotoxic effects of mistletoe (Viscum album L.) in head and neck squamous cell carcinoma cell lines

M. Fátima G. Klingbeil, Flávia C.A. Xavier, Luiz R. Sardinha, Patricia Severino, Monica B. Mathor, Rodrigo V. Rodrigues, Décio S. Pinto
Pages: 2316-2322
Published online on: 10 September 2013

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Article

Promoting effects on the proliferation and metastasis of ACC tumor cell with XAGE-1b overexpression

Bo Zhou, Tingxiu Li, Yang Liu, Naishuo Zhu
Pages: 2323-2335
Published online on: 05 September 2013

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Article

Flavonoids from Citrus unshiu Marc. inhibit cancer cell adhesion to endothelial cells by selective inhibition of VCAM-1

Hana Jin, Won Sup Lee, Jeong Won Yun, Ji Hyun Jung, Sang Mi Yi, Hye Jung Kim, Yung Hyun Choi, Gonsup Kim, Jin-Myung Jung, Chung Ho Ryu, Sung Chul Shin, Soon Chan Hong
Pages: 2336-2342
Published online on: 30 August 2013

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Article

Cisplatin regulates SH-SY5Y cell growth through downregulation of BDNF via miR-16

Yun-Xiao Sun, Jian Yang, Ping-Yu Wang, You-Jie Li, Shu-Yang Xie, Ruo-Peng Sun
Pages: 2343-2349
Published online on: 10 September 2013

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Article

RAB38 confers a poor prognosis, associated with malignant progression and subtype preference in glioma

Hongjun Wang, Chuanlu Jiang
Pages: 2350-2356
Published online on: 10 September 2013

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Article

A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells

Kriengsak Lirdprapamongkol, Hiroaki Sakurai, Sherif Abdelhamed, Satoru Yokoyama, Takeyuki Maruyama, Sirivan Athikomkulchai, Amornrat Viriyaroj, Suresh Awale, Hideo Yagita, Somsak Ruchirawat, Jisnuson Svasti, Ikuo Saiki
Pages: 2357-2364
Published online on: 20 August 2013

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Article

Glyoxalase 1 as a candidate for indicating the metastatic potential of SN12C human renal cell carcinoma cell clones

Toshiyuki Tanaka, Yasuhiro Kuramitsu, Yufeng Wang, Byron Baron, Takao Kitagawa, Kazuhiro Tokuda, Kosei Hirakawa, Masakazu Yashiro, Seiji Naito, Kazuyuki Nakamura
Pages: 2365-2370
Published online on: 27 August 2013

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Article

mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma

Dana Macejová, Štefan Galbavý, Ján Podoba, Lucia Bialešová, Július Brtko
Pages: 2371-2378
Published online on: 20 August 2013

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Article

Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation

Momoko Todo, Mano Horinaka, Mitsuhiro Tomosugi, Ryoichi Tanaka, Haruna Ikawa, Yoshihiro Sowa, Hideki Ishikawa, Hitoshi Fujiwara, Eigo Otsuji, Toshiyuki Sakai
Pages: 2379-2384
Published online on: 30 August 2013

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Article

Predictive value of ERCC1 and RRM1 gene single-nucleotide polymorphisms for first-line platinum- and gemcitabine-based chemotherapy in non-small cell lung cancer patients

Radosław Mlak, Paweł Krawczyk, Rodryg Ramlau, Ewa Kalinka-Warzocha, Maja Wasylecka-Morawiec, Kamila Wojas-Krawczyk, Tomasz Kucharczyk, Iwona Homa, Piotr Kozioł, Marzanna Ciesielka, Dorota Chudziak, Janusz Milanowski
Pages: 2385-2398
Published online on: 26 August 2013

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Article

microRNA-18b is upregulated in breast cancer and modulates genes involved in cell migration

Miguel A. Fonseca-Sanchéz, Carlos Pérez-Plasencia, Jorge Fernández-Retana, Elena Arechaga-Ocampo, Laurence A. Marchat, Sergio Rodríguez-Cuevas, Veronica Bautista-Piña, Zaira E. Arellano-Anaya, Ali Flores-Pérez, José Diaz-Chávez, César López-Camarillo
Pages: 2399-2410
Published online on: 22 August 2013

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Article

Pretreatment of baicalin and wogonoside with glycoside hydrolase: A promising approach to enhance anticancer potential

Chunhao Yu, Zhiyu Zhang, Haijiang Zhang, Zhong Zhen, Tyler Calway, Yunwei Wang, Chun-Su Yuan, Chong-Zhi Wang
Pages: 2411-2418
Published online on: 09 September 2013

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Article

3,3'-Diindolylmethane suppresses the growth of gastric cancer cells via activation of the Hippo signaling pathway

Xiu Juan Li, Eun Sung Park, Man Hee Park, Soo Mi Kim
Pages: 2419-2426
Published online on: 04 September 2013

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Article

Arsenic disulfide induces apoptosis of human diffuse large B cell lymphoma cells involving Bax cleavage

Ling Wang, Xinyu Liu, Xianglu Li, Xiao Lv, Kang Lu, Na Chen, Peipei Li, Xin Wang
Pages: 2427-2434
Published online on: 10 September 2013

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Article

The relationship between vagal nerve activity and clinical outcomes in prostate and non-small cell lung cancer patients

Marijke De Couck, David van Brummelen, Denis Schallier, Jacques De Grève, Yori Gidron
Pages: 2435-2441
Published online on: 09 September 2013

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Article

B7-H1 protein vaccine induces protective and therapeutic antitumor responses in SP2/0 myeloma-bearing mice

Cun Zhang, Weihua Wang, Xin Qin, Yujin Xu, Tonglie Huang, Qiang Hao, Weina Li, Shouzhen Wu, Yingqi Zhang
Pages: 2442-2448
Published online on: 22 August 2013

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Article

Metformin suppresses hepatocellular carcinoma cell growth through induction of cell cycle G1/G0 phase arrest and p21CIP and p27KIP expression and downregulation of cyclin D1 in vitro and in vivo

Xianbin Cai, Xi Hu, Bozhi Cai, Qinjia Wang, Youfeng Li, Xiaojun Tan, Hui Hu, Xiaofeng Chen, Jiexiong Huang, Jidong Cheng, Xubin Jing
Pages: 2449-2457
Published online on: 04 September 2013

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Article

The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer

Luís S. Santos, Bruno C. Gomes, Rita Gouveia, Susana N. Silva, Ana  P. Azevedo, Vanessa Camacho, Isabel Manita, Octávia M. Gil, Teresa  C. Ferreira, Edward Limbert, José Rueff, Jorge F. Gaspar
Pages: 2458-2466
Published online on: 27 August 2013

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Article

Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway

Haili Huang, Min Hu, Rui Zhao, Peng Li, Mingyi Li
Pages: 2467-2475
Published online on: 29 August 2013

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Expression of angiogenic factors in hepatocarcinogenesis: Identification by antibody arrays

Takako Nomura, Asahiro Morishita, Gong Jian, Shima Mimura, Kiyohito Kato, Kei Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Teppei Sakamoto, Koji Fujita, Emiko Maeda, Hideki Kobara, Hirohito Mori, Hisakazu Iwama, Tsutomu Masaki
Pages: 2476-2480
Published online on: 20 August 2013

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Serum HE4 levels combined with CE CT imaging improve the management of monitoring women affected by epithelial ovarian cancer

Lucia Manganaro, Simona Michienzi, Valeria Vinci, Renato Falzarano, Matteo Saldari, Teresa Granato, Valentina Viggiani, Luigi Frati, Emanuela Anastasi
Pages: 2481-2487
Published online on: 21 August 2013

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Article

Progesterone protects ovarian cancer cells from cisplatin-induced inhibitory effects through progesterone receptor membrane component 1/2 as well as AKT signaling

Xiaofei Zhu, Yue Han, Zhuyuan Fang, Wenzhong Wu, Mingde Ji, Fengmeng Teng, Wei Zhu, Xuewen Yang, Xuemei Jia, Chunbing Zhang
Pages: 2488-2494
Published online on: 21 August 2013

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Article

HIF-1α inhibition sensitizes pituitary adenoma cells to temozolomide by regulating MGMT expression

Wenna Chen, Zheng Xiao, Yachao Zhao, Lina Huang, Ganqin Du
Pages: 2495-2501
Published online on: 22 August 2013

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The cathelicidin-BF Lys16 mutant Cbf-K16 selectively inhibits non-small cell lung cancer proliferation in vitro

Yuwei Tian, Hui Wang, Bing Li, Mengyun Ke, Jing Wang, Jie Dou, Changlin Zhou
Pages: 2502-2510
Published online on: 23 August 2013

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Article

Glucosidase II exhibits similarity to the p53 tumor suppressor in regards to structure and behavior in response to stress signals: A potential novel cancer biomarker

Benjamart Suradej, Supansa Pata, Watchara Kasinrerk, Ratchada Cressey
Pages: 2511-2519
Published online on: 05 September 2013

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Article

Expression and prognostic significance of Livin in gastric cancer

Cho-Yun Chung, Young-Lan Park, Nuri Kim, Hyung-Chul Park, Hyun-Bum Park, Dae-Seong Myung, Jong-Sun Kim, Sung-Bum Cho, Wan-Sik Lee, Young-Eun Joo
Pages: 2520-2528
Published online on: 06 September 2013

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Article

Matrine induction of reactive oxygen species activates p38 leading to caspase-dependent cell apoptosis in non-small cell lung cancer cells

Caihong Tan, Xiaoqiang Qian, Rongdi Jia, Min Wu, Zhongqin Liang
Pages: 2529-2535
Published online on: 09 September 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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