Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
presentation
Molecular Medicine Reports

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Board
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
September-2017 Volume 16 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Cassiae semen: A review of its phytochemistry and pharmacology (Review)

Xiaoxv Dong, Jing Fu, Xingbin Yin, Chunjing Yang, Xin Zhang, Wenping Wang, Xueying Du, Qingling Wang, Jian Ni
Pages: 2331-2346
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Proteomic analysis and comparison of intra‑ and extracranial cerebral atherosclerosis responses to hyperlipidemia in rabbits

Zhi‑Lan Tu, Bo Yu, Dong‑Ya Huang, Rajeev Ojha, Shu‑Kui Zhou, He‑Di An, Rong Liu, Cui Du, Nan Shen, Jian‑Hui Fu, Shuang‑Xing Hou
Pages: 2347-2354
Published online on: 28 June 2017

  • View Full Article Download
Article

Active exercise promotes Achilles tendon healing and is accompanied by the upregulation of collapsin response mediator protein‑2 in rats

Bayixiati Qianman, Ayidaer Jialihasi, Batiza Asilehan, Aliya Kubai, Rakimbaiev Aibek, Aikeremu Wupuer, Wulanbai Tangkejie, Abudouheilil Maimaitiaili, Nuerai Shawutali, Aynaz Badelhan, Adili Aizezi, Amuding Aisaiding, Jianati Wuerliebieke, Yerzat Bakyt, Elihaer Makemutibieke, Jiasharete Jielile
Pages: 2355-2360
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Circulating level of high mobility group box‑1 predicts the severity of community‑acquired pneumonia: Regulation of inflammatory responses via the c‑Jun N‑terminal signaling pathway in macrophages

Hsiang‑Ling Wang, Shih‑Ming Tsao, Chao‑Bin Yeh, Ying‑Erh Chou, Shun‑Fa Yang
Pages: 2361-2366
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Serum biomarker analysis in patients with recurrent spontaneous abortion

Ying Wu, Junqin He, Chunyu Guo, Ying Zhang, Wei Yang, Mingwei Xin, Xinyun Liang, Xiaodan Yin, Jingshang Wang, Yanfeng Liu
Pages: 2367-2378
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Protein profiling and functional analysis of liver mitochondria from rats with nonalcoholic steatohepatitis

Yanting You, Yuxing Zhang, Yuanyuan Lu, Keke Hu, Xiaohu Qu, Yongzhag Liu, Bin Lu, Liqin Jin
Pages: 2379-2388
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

JNK signaling is required for the MIP‑1α‑associated regulation of Kupffer cells in the heat stroke response

Xiao‑Juan Chen, Zhong‑Zhi Tang, Guo‑Guo Zhu, Qing Cheng, Wen‑Kai Zhang, Hui‑Min Li, Wei Fu, Qi‑Ping Lu
Pages: 2389-2396
Published online on: 05 July 2017

  • View Full Article Download
Article Open Access

Systematic identification of human housekeeping genes possibly useful as references in gene expression studies

Maria Caracausi, Allison Piovesan, Francesca Antonaros, Pierluigi Strippoli, Lorenza Vitale, Maria Chiara Pelleri
Pages: 2397-2410
Published online on: 06 July 2017

  • View Full Article Download
Article

Network analysis of HBV‑ and HCV‑induced hepatocellular carcinoma based on Random Forest and Monte Carlo cross‑validation

Shan‑Na Zhao, Ling‑Ling Liu, Zhi‑Ping Lv, Xiao‑Hua Wang, Cheng‑Hong Wang
Pages: 2411-2416
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

miR‑199a‑3p is involved in the pathogenesis and progression of diabetic neuropathy through downregulation of SerpinE2

Ying‑Bo Li, Qun Wu, Jie Liu, Yong‑Zhi Fan, Kai‑Feng Yu, Yi Cai
Pages: 2417-2424
Published online on: 28 June 2017

  • View Full Article Download
Article Open Access

PM2.5 exposure decreases viability, migration and angiogenesis in human umbilical vein endothelial cells and human microvascular endothelial cells

Shengguang Chen, Xianzheng Wu, Jiawen Hu, Guoxing Dai, Aihong Rong, Gang Guo
Pages: 2425-2430
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

miR‑30c suppresses prostate cancer survival by targeting the ASF/SF2 splicing factor oncoprotein

Ya‑Qiang Huang, Xiao‑Hui Ling, Run‑Qiang Yuan, Zhi‑Yun Chen, Sheng‑Bang Yang, Hong‑Xing Huang, Wei‑De Zhong, Shao‑Peng Qiu
Pages: 2431-2438
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Effects of moderate‑intensity endurance exercise on angiotensin II and angiotensin II type I receptors in the rat heart

Xin Li, Kun Wang
Pages: 2439-2444
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

Caffeine induces sustained apoptosis of human gastric cancer cells by activating the caspase‑9/caspase‑3 signalling pathway

Hanyang Liu, Yan Zhou, Liming Tang
Pages: 2445-2454
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Expression and antimicrobial character of cells transfected with human β‑defensin‑3 against periodontitis‑associated microbiota in vitro

Minwen Zhu, Bo Miao, Jianhua Zhu, Haiyan Wang, Zengtong Zhou
Pages: 2455-2460
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Traditional Chinese medicine, Fuzheng Kang‑Ai decoction, inhibits metastasis of lung cancer cells through the STAT3/MMP9 pathway Corrigendum in /10.3892/mmr.2021.12244

Longmei Li, Sumei Wang, Xiaobin Yang, Shunqin Long, Shujing Xiao, Wanyin Wu, Swei Sunny Hann
Pages: 2461-2468
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Expression profile of circular RNAs in human gastric cancer tissues

You‑Sheng Huang, Na Jie, Ke‑Jian Zou, Yang Weng
Pages: 2469-2476
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Lysyl oxidase‑like 2 is expressed in kidney tissue and is associated with the progression of tubulointerstitial fibrosis

Sung‑Eun Choi, Nara Jeon, Hoon Young Choi, Jae Il Shin, Hyeon Joo Jeong, Beom Jin Lim
Pages: 2477-2482
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Chitosan promotes immune responses, ameliorating total mature white blood cell numbers, but increases glutamic oxaloacetic transaminase and glutamic pyruvic transaminase, and ameliorates lactate dehydrogenase levels in leukemia mice in vivo

Ming‑Yang Yeh, Yung‑Luen Shih, Hsueh‑Yu Chung, Jason Chou, Hsu‑Feng Lu, Chia‑Hui Liu, Jia‑You Liu, Wen‑Wen Huang, Shu‑Fen Peng, Lung‑Yuan Wu, Jing‑Gung Chung
Pages: 2483-2490
Published online on: 05 July 2017

  • View Full Article Download
Article Open Access

Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS‑induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF‑κB signaling pathways

Aijuan Yan, Gaoyu Cai, Weiliang Xia, Yi Fu
Pages: 2491-2496
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Telomere length is positively associated with the expression of IL‑6 and MIP‑1α in bone marrow mesenchymal stem cells of multiple myeloma

Shengli Li, Yang Jiang, Ai Li, Xiaoli Liu, Xiangling Xing, Yanan Guo, Yaqi Xu, Yunliang Hao, Chengyun Zheng
Pages: 2497-2504
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Two heterozygous mutations identified in one Chinese patient with bilateral macular coloboma

Tao Li, Ying Lin, Hongbin Gao, Chuan Chen, Yi Zhu, Bingqian Liu, Yu Lian, Yonghao Li, Wenli Zhou, Hongye Jiang, Haichun Li, Qingxiu Wu, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu
Pages: 2505-2510
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Yi Guan Jian decoction may enhance hepatic differentiation of bone marrow‑derived mesenchymal stem cells via SDF‑1 in vitro

Lin‑Lin Fu, Bing‑Yao Pang, Ying Zhu, Ling Wang, Ai‑Jing Leng, Hai‑Long Chen
Pages: 2511-2521
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

MicroRNA‑21 promotes neurite outgrowth by regulating PDCD4 in a rat model of spinal cord injury

Yuqing Jiang, Shujie Zhao, Yin Ding, Luming Nong, Haibo Li, Gongming Gao, Dong Zhou, Nanwei Xu
Pages: 2522-2528
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

Interleukin‑6 RNA knockdown ameliorates acute lung injury induced by intestinal ischemia reperfusion in rats by upregulating interleukin‑10 expression

Bing Yuan, Liu‑Lin Xiong, Mu‑Dong Wen, Piao Zhang, Hong‑Yu Ma, Ting‑Hua Wang, Yun‑Hui Zhang
Pages: 2529-2537
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation

Yadong Zhang, Shiyi Dong, Jianning Wang, Miao Wang, Mu Chen, Hongzhang Huang
Pages: 2538-2546
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Identification of a gene expression profile associated with the regulation of angiogenesis in endometrial cancer

Marcin Opławski, Mateusz Michalski, Andrzej Witek, Bogdan Michalski, Nikola Zmarzły, Agnieszka Jęda‑Golonka, Maria Styblińska, Joanna Gola, Małgorzata Kasprzyk‑Żyszczyńska, Urszula Mazurek, Andrzej Plewka
Pages: 2547-2555
Published online on: 28 June 2017

  • View Full Article Download
Article Open Access

Lentivirus‑mediated RIG‑I knockdown relieves cell proliferation inhibition, cell cycle arrest and apoptosis in ATRA‑induced NB4 cells via the AKT‑FOXO3A signaling pathway in vitro

Lei Chen, Ya‑Bin Cui, Yu‑Ling Si, Wei‑Dong Su, Xin‑Chao Wang, Hua Pang, Li‑Jun Qiu
Pages: 2556-2562
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

Spectrum construction of differentially expressed circular RNAs in patients with leukoaraiosis and function analysis of differentially expressed genes

Te Mi, Changjiang Luo, Yawei Hu, Chuanqiang Qu, Xiang Wang, Shougang Guo, Yifeng Du
Pages: 2563-2569
Published online on: 28 June 2017

  • View Full Article Download
Article Open Access

miRNA‑504 inhibits p53‑dependent vascular smooth muscle cell apoptosis and may prevent aneurysm formation

Xue Cao, Zhenguo Cai, Junyan Liu, Yanru Zhao, Xin Wang, Xueqi Li, Hongyuan Xia
Pages: 2570-2578
Published online on: 28 June 2017

  • View Full Article Download
Article Open Access

Oxidative stress regulates mitogen‑activated protein kinases and c‑Jun activation involved in heat stress and lipopolysaccharide‑induced intestinal epithelial cell apoptosis

Yanan Liu, Zhenglian Wang, Weidang Xie, Zhengtao Gu, Qiulin Xu, Lei Su
Pages: 2579-2587
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

Curcumin pretreatment protects against PM2.5‑induced oxidized low‑density lipoprotein‑mediated oxidative stress and inflammation in human microvascular endothelial cells

Jun Shi, Huiping Deng, Min Zhang
Pages: 2588-2594
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

In vitro anticancer effects of two novel phenanthroindolizidine alkaloid compounds on human colon and liver cancer cells

Jingjing Liu, Yu He, Dan Zhang, Ying Cai, Chenggang Zhang, Peng Zhang, Hongxia Zhu, Ningzhi Xu, Shufang Liang
Pages: 2595-2603
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

miR‑433 protects pancreatic β cell growth in high‑glucose conditions

Min Wang
Pages: 2604-2610
Published online on: 05 July 2017

  • View Full Article Download
Article Open Access

Pien Tze Huang Gan Bao attenuates carbon tetrachloride‑induced hepatocyte apoptosis in rats, associated with suppression of p53 activation and oxidative stress

Jinyan Zhao, Yuchen Zhang, Yun Wan, Haixia Hu, Zhenfeng Hong
Pages: 2611-2619
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Effects of RMF on BKCa and Kv channels in basilar arterial smooth‑muscle cells of SHR

Yan‑Fei Qian, Yang Wang, Wei‑Wei Tian, Sheng Wang, Lei Zhao, Li Li, Ke‑Tao Ma, Jun‑Qiang Si
Pages: 2620-2626
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Role of miR‑21 on vascular endothelial cells in the protective effect of renal delayed ischemic preconditioning

Xialian Xu, Xiaoyan Jiao, Nana Song, Weili Luo, Mingyu Liang, Xiaoqiang Ding, Jie Teng
Pages: 2627-2635
Published online on: 28 June 2017

  • View Full Article Download
Article Open Access

Peroxisome proliferator‑activated receptor γ mediates porcine placental angiogenesis through hypoxia inducible factor‑, vascular endothelial growth factor‑ and angiopoietin‑mediated signaling

Juzuo Zhang, Xuan Peng, Anwen Yuan, Yang Xie, Qing Yang, Liqun Xue
Pages: 2636-2644
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Silencing of β1 integrin regulates airway remodeling by regulating the transcription of SOCE‑associated genes in asthmatic mice

Chen Qiu, Wenwen Liu, Fei Shi, Mengjie Fen, Lili Ren, Hui Qi
Pages: 2645-2651
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

miR-320a serves as a negative regulator in the progression of gastric cancer by targeting RAB14

Yongyuan Li, Hongjie Liu, Jianping Shao, Guoqiang Xing
Pages: 2652-2658
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Oral squamous cell carcinoma cells are resistant to doxorubicin through upregulation of miR‑221

Liangzhi Du, Siwei Ma, Xi Wen, Juan Chai, Dangxia Zhou
Pages: 2659-2667
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Protective effects of SOCS3 overexpression in high glucose‑induced lung epithelial cell injury through the JAK2/STAT3 pathway

Wei‑Na Duan, Zhong‑Yuan Xia, Min Liu, Qian Sun, Shao‑Qing Lei, Xiao‑Jing Wu, Qing‑Tao Meng, Yan Leng
Pages: 2668-2674
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Endothelial growth medium suppresses apoptosis of mesenchymal stem cells in vitro via decrease of miR‑29a

Qianqian Wu, Tao Fang, Min Chen, Guoxian Qi
Pages: 2675-2681
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Variant SNPs at the microRNA complementary site in the B7‑H1 3'‑untranslated region increase the risk of non‑small cell lung cancer

Wenwen Du, Jianjie Zhu, Yanbin Chen, Yuanyuan Zeng, Dan Shen, Nan Zhang, Weiwei Ning, Zeyi Liu, Jian‑An Huang
Pages: 2682-2690
Published online on: 30 June 2017

  • View Full Article Download
Article Open Access

Serum is an indispensable factor in the maintenance of the biological characteristics of sweat gland cells

Qing Sun, Xiao‑Mei Deng, Yun‑Liang Wang, Yun‑Fang Zhen, Fang Li, Rui‑Hua Chen, Han‑Si Liang, Feng Zhang, Ming‑De Qin, Xue‑Guang Zhang
Pages: 2691-2699
Published online on: 04 July 2017

  • View Full Article Download
Article Open Access

Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway

Xujiao Huang, Sanli Xing, Chuan Chen, Zhihua Yu, Jiulin Chen
Pages: 2700-2706
Published online on: 05 July 2017

  • View Full Article Download
Article Open Access

Microarray analysis reveals key genes and pathways in Tetralogy of Fallot

Yue‑E He, Hui‑Xian Qiu, Jian‑Bing Jiang, Rong‑Zhou Wu, Ru‑Lian Xiang, Yuan‑Hai Zhang
Pages: 2707-2713
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

Activation of the HMGB1‑TLR4‑NF‑κB pathway may occur in patients with atopic eczema

Yong Wang, Hui Weng, Jian Fei Song, Yun Hua Deng, Shuang Li, Hong Bo Liu
Pages: 2714-2720
Published online on: 06 July 2017

  • View Full Article Download
Article Open Access

TFE3 regulates renal adenocarcinoma cell proliferation via activation of the mTOR pathway

Yuan Fang, Wei Bao, Qiu Rao, Xuan Wang, Qiuyuan Xia, Qin Shen, Xiaojun Zhou, Bing Yao
Pages: 2721-2725
Published online on: 05 July 2017

  • View Full Article Download
Article Open Access

Wild‑type blocking pcr coupled with internal competitive amplified fragment improved the detection of rare mutation of KRAS

Jia Peng, Kun Wei, Xiang Zhao, Ke Yang, Huan Wang, Yang Zhang, Mei Guo, Jing He, Haiyan Wu, Yongchuan Li, Na Zhao, Qing Huang, Weiling Fu
Pages: 2726-2732
Published online on: 29 June 2017

  • View Full Article Download
Article Open Access

Matrine increases the inhibitory effects of afatinib on H1975 cells via the IL‑6/JAK1/STAT3 signaling pathway

Shui‑Fang Chen, Ze‑Ying Zhang, Jian‑Li Zhang
Pages: 2733-2739
Published online on: 27 June 2017

  • View Full Article Download
Article Open Access

Hypertrophic differentiation of mesenchymal stem cells is suppressed by xanthotoxin via the p38‑MAPK/HDAC4 pathway

Zhen Cao, Yun Bai, Chuan Liu, Ce Dou, Jianmei Li, Junyu Xiang, Chunrong Zhao, Zhao Xie, Qiang Xiang, Shiwu Dong
Pages: 2740-2746
Published online on: 29 June 2017

  • View Full Article Download
Article

MESP1 loss‑of‑function mutation contributes to double outlet right ventricle

Min Zhang, Fu‑Xing Li, Xing‑Yuan Liu, Ri‑Tai Huang, Song Xue, Xiao‑Xiao Yang, Yan‑Jie Li, Hua Liu, Hong‑Yu Shi, Xin Pan, Xing‑Biao Qiu, Yi‑Qing Yang
Pages: 2747-2754
Published online on: 29 June 2017

  • View Full Article Download
Article

NICD inhibits cell proliferation and promotes apoptosis and autophagy in PC12 cells

Bo Li, Ping Duan, Xuefei Han, Wenhai Yan, Ying Xing
Pages: 2755-2760
Published online on: 29 June 2017

  • View Full Article Download
Article

Astragaloside IV downregulates the expression of MDR1 in Bel‑7402/FU human hepatic cancer cells by inhibiting the JNK/c‑Jun/AP‑1 signaling pathway

Pei‑Pei Wang, Jia‑Jie Luan, Wen‑Ke Xu, Lin Wang, Du‑Juan Xu, Chun‑Yan Yang, Yan‑Hong Zhu, Ya‑Qin Wang
Pages: 2761-2766
Published online on: 05 July 2017

  • View Full Article Download
Article

Inhibition of aldose reductase ameliorates alcoholic liver disease by activating AMPK and modulating oxidative stress and inflammatory cytokines

Changxuan Shi, Yuanfang Wang, Jing Gao, Si Chen, Xiangqian Zhao, Chengchao Cai, Chang Guo, Longxin Qiu
Pages: 2767-2772
Published online on: 30 June 2017

  • View Full Article Download
Article

Upregulation of HOXB7 promotes proliferation and metastasis of osteosarcoma cells

Yang Yang, Jing Chen, Qingzhong Chen
Pages: 2773-2778
Published online on: 30 June 2017

  • View Full Article Download
Article

Inhibition of neuropeptide Y Y1 receptor induces osteoblast differentiation in MC3T3‑E1 cells

Motoki Yahara, Kanchu Tei, Masato Tamura
Pages: 2779-2784
Published online on: 27 June 2017

  • View Full Article Download
Article

Effects of lentiviral vector‑mediated shRNA silencing of TGFβ1 on the expression of Col1a1 in rat hepatic stellate cells

Gan‑Ping Bai, Guo‑He Yan, Guo‑Jian Wang, Ping Wan, Xiao‑Fei Liu, Heng Wang, Rong‑Hua Zhang
Pages: 2785-2790
Published online on: 06 July 2017

  • View Full Article Download
Article

Human decidua mesenchymal stem cells regulate decidual natural killer cell function via interactions between collagen and leukocyte‑associated immunoglobulin‑like receptor 1

Qiang Fu, Xuejing Man, Min Yu, Yongli Chu, Xiying Luan, Hailan Piao, Jiangnan Xue, Changzhu Jin
Pages: 2791-2798
Published online on: 05 July 2017

  • View Full Article Download
Article

Identification of potential target genes associated with the pathogenesis of osteoarthritis using microarray based analysis

Meng Li, Liqiang Zhi, Zhi Zhang, Weiguo Bian, Yusheng Qiu
Pages: 2799-2806
Published online on: 05 July 2017

  • View Full Article Download
Article

Alanyl‑glutamine prophylactically protects against lipopolysaccharide‑induced acute lung injury by enhancing the expression of HSP70

Haitang Wang, Yinv Dong, Yehua Cai
Pages: 2807-2813
Published online on: 30 June 2017

  • View Full Article Download
Article

Protective effect and mechanism of ginsenoside Rg1 on carbon tetrachloride‑induced acute liver injury

Benquan Qi, Suzhi Zhang, Daohua Guo, Sanxing Guo, Xiaodong Jiang, Xiling Zhu
Pages: 2814-2822
Published online on: 05 July 2017

  • View Full Article Download
Article

Osthole attenuates pulmonary arterial hypertension in monocrotaline‑treated rats

Yeli Li, Yingwan Wang, Yiqi Li, Zhiqiang Qian, Ling Zhu, Danli Yang
Pages: 2823-2829
Published online on: 29 June 2017

  • View Full Article Download
Article

Identification of a compound heterozygous mutation of ABCC2 in a patient with hyperbilirubinemia

Rong Xiang, Jing‑Jing Li, Liang‑Liang Fan, Jie‑Yuan Jin, Kun Xia, Fang Wang
Pages: 2830-2834
Published online on: 05 July 2017

  • View Full Article Download
Article

MicroRNA profiling of platelets from immune thrombocytopenia and target gene prediction

Gang Deng, Shifang Yu, Yunlei He, Tao Sun, Wei Liang, Lu Yu, Deyi Xu, Qiang Li, Ri Zhang
Pages: 2835-2843
Published online on: 30 June 2017

  • View Full Article Download
Article

Grape seed procyanidin B2 ameliorates hepatic lipid metabolism disorders in db/db mice

Mei Yin, Pei Zhang, Fei Yu, Zhen Zhang, Qian Cai, Weida Lu, Baoying Li, Weidong Qin, Mei Cheng, Hao Wang, Haiqing Gao
Pages: 2844-2850
Published online on: 30 June 2017

  • View Full Article Download
Article

Expression, purification and epitope analysis of Pla a 3 allergen from Platanus acerifolia pollen

Wei‑Wei Ni, Li‑Bing Wang, Yan‑Jun Zhou, Meng‑Da Cao, Wen Huang, Miao Guo, Chun‑Mei Ji, Jin‑Lu Sun, Ji‑Fu Wei
Pages: 2851-2855
Published online on: 28 June 2017

  • View Full Article Download
Article

Cloning of the promoter region of a human gene, FOXL2, and its regulation by STAT3

Yangyang Han, Tianxiao Wang, Shudong Sun, Zhaohui Zhai, Shengjian Tang
Pages: 2856-2862
Published online on: 04 July 2017

  • View Full Article Download
Article

Potential role of upregulated microRNA‑146b and ‑21 in renal fibrosis

Guangda Xin, Guangyu Zhou, Xiaofei Zhang, Wanning Wang
Pages: 2863-2867
Published online on: 05 July 2017

  • View Full Article Download
Article

Chemotherapy oxaliplatin sensitizes prostate cancer to immune checkpoint blockade therapies via stimulating tumor immunogenicity

Jin Zhou, Tuo Yang, Lipeng Liu, Bingxin Lu
Pages: 2868-2874
Published online on: 30 June 2017

  • View Full Article Download
Article

Molecular mechanism and functional role of macrophage colony‑stimulating factor in follicular granulosa cells

Zhang Wei, Xu Song, Zhang Zhifen
Pages: 2875-2880
Published online on: 27 June 2017

  • View Full Article Download
Article

Resveratrol suppresses thyroid hormone‑induced osteocalcin synthesis in osteoblasts

Kazuhiko Fujita, Haruhiko Tokuda, Shingo Kainuma, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Atsushi Harada, Osamu Kozawa, Takanobu Otsuka
Pages: 2881-2886
Published online on: 28 June 2017

  • View Full Article Download
Article

Expression and purification of a major allergen, Pla a 1, from Platanus acerifolia pollen and the preparation of its monoclonal antibody

Wei‑Wei Ni, Wen Huang, De‑Qin Wu, Yan‑Jun Zhou, Chun‑Mei Ji, Meng‑Da Cao, Miao Guo, Jin‑Lu Sun, Ji‑Fu Wei
Pages: 2887-2892
Published online on: 30 June 2017

  • View Full Article Download
Article

Analysis of murine and human Treg subsets in inflammatory bowel disease

Xiaoyun Sun, Shaoheng He, Changlong Lv, Xun Sun, Junling Wang, Wenjiao Zheng, Danan Wang
Pages: 2893-2898
Published online on: 04 July 2017

  • View Full Article Download
Article

Human trypsin inhibitor reduces the apoptosis of lipopolysaccharide‑induced human kidney‑2 cells by promoting mitochondrial fusion

Ning Liu, Zhiyi Jiang, Yongjun Liu, Yao Nie, Juan Chen, Bin Ouyang, Xiangdong Guan, Minying Chen
Pages: 2899-2906
Published online on: 05 July 2017

  • View Full Article Download
Article

Ginsenoside Rc protects against UVB‑induced photooxidative damage in epidermal keratinocytes

Yuri Oh, Hye‑Won Lim, Kwang Hark Park, Yu‑Hua Huang, Ji‑Young Yoon, Kyunghoon Kim, Chang‑Jin Lim
Pages: 2907-2914
Published online on: 06 July 2017

  • View Full Article Download
Article

Bioinformatics analysis of key genes and signaling pathways associated with myocardial infarction following telomerase activation

Yi Yang, Guang Yang, Hongwei Du, Nana Dong, Bo Yu
Pages: 2915-2924
Published online on: 06 July 2017

  • View Full Article Download
Article

Vaspin prevents leptin‑induced inflammation and catabolism by inhibiting the activation of nuclear factor‑κB in rat chondrocytes

Jia‑Peng Bao, Lang‑Hai Xu, Ji‑Sheng Ran, Yan Xiong, Li‑Dong Wu
Pages: 2925-2930
Published online on: 04 July 2017

  • View Full Article Download
Article

The function of androgen/androgen receptor and insulin growth factor‑1/insulin growth factor‑1 receptor on the effects of Tribulus terrestris extracts in rats undergoing high intensity exercise

Yin Wu, Hongfang Yang, Xiaohui Wang
Pages: 2931-2938
Published online on: 30 June 2017

  • View Full Article Download
Article

Ameliorative efficacy of quercetin against cisplatin‑induced mitochondrial dysfunction: Study on isolated rat liver mitochondria

Mohammad Waseem, Heena Tabassum, Monica Bhardwaj, Suhel Parvez
Pages: 2939-2945
Published online on: 27 June 2017

  • View Full Article Download
Article

Long non‑coding RNA MEG3 contributes to cisplatin‑induced apoptosis via inhibition of autophagy in human glioma cells

Binbin Ma, Zebin Gao, Jiacheng Lou, Hongqiang Zhang, Zhongbo Yuan, Qiong Wu, Xinyu Li, Bo Zhang
Pages: 2946-2952
Published online on: 30 June 2017

  • View Full Article Download
Article

Sasanquasaponin induces increase of Cl‑/HCO3‑ exchange of anion exchanger 3 and promotes intracellular Cl‑ efflux in hypoxia/reoxygenation cardiomyocytes

Ling‑Yu Qiu, Guang-Ling Duan, Yu‑Feng Yan, Yuan‑Yuan Li, Huan Wang, Ling Xiao, Zhang‑Ping Liao, He‑Ping Chen
Pages: 2953-2961
Published online on: 29 June 2017

  • View Full Article Download
Article

TNFR2 promotes Adriamycin resistance in breast cancer cells by repairing DNA damage

Fuqian Yang, Nana Zhao, Nan Wu
Pages: 2962-2968
Published online on: 30 June 2017

  • View Full Article Download
Article

Overexpression of SIRT1 prevents hypoxia‑induced apoptosis in osteoblast cells

Lu Zhou, Sung Il Wang, Young Jae Moon, Kyoung Min Kim, Kwang Bok Lee, Byung‑Hyun Park, Kyu Yun Jang, Jung Ryul Kim
Pages: 2969-2975
Published online on: 04 July 2017

  • View Full Article Download
Article

Involvement of exogenous 3‑deoxyglucosone in β‑cell dysfunction induces impaired glucose regulation

Lurong Zhang, Liang Zhou, Xiudao Song, Guoqiang Liang, Zhongrui Xu, Fei Wang, Fei Huang, Guorong Jiang
Pages: 2976-2984
Published online on: 27 June 2017

  • View Full Article Download
Article

Baicalin prevents the apoptosis of endplate chondrocytes by inhibiting the oxidative stress induced by H2O2

Yutao Pan, Di Chen, Qingyou Lu, Lifeng Liu, Xia Li, Zengchun Li
Pages: 2985-2991
Published online on: 30 June 2017

  • View Full Article Download
Article

Downregulation of microRNA‑199a‑5p protects cardiomyocytes in cyanotic congenital heart disease by attenuating endoplasmic reticulum stress

Yang Zhou, Wei‑Kun Jia, Zhao Jian, Liang Zhao, Chen‑Cheng Liu, Yong Wang, Ying‑Bin Xiao
Pages: 2992-3000
Published online on: 06 July 2017

  • View Full Article Download
Article

General regulatory effects of hypoxia on human cartilage endplate‑derived stem cells: A genome‑wide analysis of differential gene expression and alternative splicing events

Yuan Yao, Weilin Song, Qiyue Deng, Huiyu Zhang, Jian Wang, Huan Liu, Yue Zhou
Pages: 3001-3009
Published online on: 30 June 2017

  • View Full Article Download
Article

Effects of epigallocatechin‑3‑gallate on iron metabolism in spinal cord motor neurons

Fengyuan Che, Guangying Wang, Jixu Yu, Xianjun Wang, Yucheng Lu, Qingxi Fu, Quanping Su, Jianzhang Jiang, Yifeng Du
Pages: 3010-3014
Published online on: 05 July 2017

  • View Full Article Download
Review

Sexual dimorphism of frailty and cognitive impairment: Potential underlying mechanisms (Review)

Qingwei Ruan, Grazia D'onofrio, Tao Wu, Antonio Greco, Daniele Sancarlo, Zhuowei Yu
Pages: 3023-3033
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

PTPRQ as a potential biomarker for idiopathic normal pressure hydrocephalus

Yuki Nagata, Masahiko Bundo, Saiko Sugiura, Masahiro Kamita, Masaya Ono, Kotaro Hattori, Sumiko Yoshida, Yu‑Ichi Goto, Katsuya Urakami, Shumpei Niida
Pages: 3034-3040
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Selection of an optimal promoter for gene transfer in normal B cells

Magdalena Winiarska, Dominika Nowis, Malgorzata Firczuk, Agnieszka Zagozdzon, Magdalena Gabrysiak, Radoslaw Sadowski, Joanna Barankiewicz, Michal Dwojak, Jakub Golab
Pages: 3041-3048
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

miRNA‑1284 inhibits cell growth and induces apoptosis of lung cancer cells

Jie Li, Hairong Jin, Hua Yu, Bin Wang, Jian Tang
Pages: 3049-3054
Published online on: 12 July 2017

  • View Full Article Download
Article Open Access

Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c‑Myc

Zhi‑Ling Shan, Liang Zhong, Chu‑Lan Xiao, Liu‑Gen Gan, Ting Xu, Hao Song, Rong Yang, Liu Li, Bei‑Zhong Liu
Pages: 3055-3060
Published online on: 13 July 2017

  • View Full Article Download
Article Open Access

MicroRNA‑126 inhibits endothelial permeability and apoptosis in apolipoprotein E‑knockout mice fed a high‑fat diet

Xiao‑Wen Cheng, Yu‑Feng Wan, Qing Zhou, Yuan Wang, Hua‑Qing Zhu
Pages: 3061-3068
Published online on: 12 July 2017

  • View Full Article Download
Article Open Access

Bone marrow mesenchymal stem cell‑derived extracellular vesicles improve the survival of transplanted fat grafts

He Huang, Shaoqing Feng, Wenjie Zhang, Wei Li, Peng Xu, Xiangsheng Wang, Ai Ai
Pages: 3069-3078
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Adipose differentiation‑related protein knockdown inhibits vascular smooth muscle cell proliferation and migration and attenuates neointima formation

Haomin Zhao, Tao Han, Xin Hong, Dajun Sun
Pages: 3079-3086
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Identification of potential biomarkers and therapeutic targets for human IgA nephropathy and hypertensive nephropathy by bioinformatics analysis

Yingchun Cui, Shengmao Liu, Wenpeng Cui, Dan Gao, Wenhua Zhou, Ping Luo
Pages: 3087-3094
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Expression and subcellular localization of AT motif binding factor 1 in colon tumours

Hiromi Kataoka, Yutaka Miura, Makoto Kawaguchi, Shugo Suzuki, Yasuyuki Okamoto, Keiji Ozeki, Takaya Shimura, Tsutomu Mizoshita, Eiji Kubota, Satoshi Tanida, Satoru Takahashi, Kiyofumi Asai, Takashi Joh
Pages: 3095-3102
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Expression and function of transforming growth factor‑β‑activated protein kinase 1 in gastric cancer

Yue Yang, Yudong Qiu, Mubai Tang, Zhaoshu Wu, Weidong Hu, Chaobo Chen
Pages: 3103-3110
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

LPS enhances TLR4 expression and IFN‑γ production via the TLR4/IRAK/NF‑κB signaling pathway in rat pulmonary arterial smooth muscle cells

Pengyan Wang, Xuhui Han, Biwen Mo, Guojin Huang, Changming Wang
Pages: 3111-3116
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Lipo‑prostaglandin E1 modifies cognitive impairment in rats with vascular cognitive impairment by promoting angiogenesis via the VEGF/VEGFR pathway

Bohui Liu, Suping Zhang, Xifeng Xiong, Li Ling, Rui He, Muzhen Wang, Wanqing Deng, Zhihe Liu, Yi Li
Pages: 3117-3124
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Protective effects of Shexiang Tongxin Dropping Pill on pituitrin‑induced acute myocardial ischemia in rats

Shan Lin, Jianfeng Chu, Ling Zhang, Daxin Chen, Fei Xiao, Hongwei Chen, Jiumao Lin, Youqin Chen, Yuling Zhu, Jun Peng
Pages: 3125-3132
Published online on: 13 July 2017

  • View Full Article Download
Article Open Access

Identification of key genes in Gram‑positive and Gram‑negative sepsis using stochastic perturbation

Zhenliang Li, Ying Zhang, Yaling Liu, Yanchun Liu, Youyi Li
Pages: 3133-3146
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Elastin‑derived peptides are involved in the processes of human temporomandibular disorder by inducing inflammatory responses in synovial cells

Kazuhiko Kobayashi, Rei Jokaji, Mayuko Miyazawa‑Hira, Shigeyuki Takatsuka, Akira Tanaka, Kazuhiro Ooi, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 3147-3154
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Exploration of the sequential gene changes in epithelial ovarian cancer induced by carboplatin via microarray analysis

Shuqing Wei, Jianwu Liu, Yuxia Shi, Xi Zhang, Yongming Yang, Qingzhen Song
Pages: 3155-3160
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Evaluation of velvet antler total protein effect on bone marrow‑derived endothelial progenitor cells

Xiang Xiao, Lin Li, Shuqiang Xu, Min Mao, Ruiyan Pan, Yanjun Li, Jiayun Wu, Li Huang, Xiaoyun Zheng
Pages: 3161-3168
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Altered axon initial segment in hippocampal newborn neurons, associated with recurrence of temporal lobe epilepsy in rats

Tian‑Tian Liu, Li Feng, Heng‑Fang Liu, Yi Shu, Bo Xiao
Pages: 3169-3178
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

GABAergic ventrolateral pre‑optic nucleus neurons are involved in the mediation of the anesthetic hypnosis induced by propofol

Jie Yuan, Zhuxin Luo, Yu Zhang, Yi Zhang, Yuan Wang, Song Cao, Bao Fu, Hao Yang, Lin Zhang, Wenjing Zhou, Tian Yu
Pages: 3179-3186
Published online on: 18 July 2017

  • View Full Article Download
Article Open Access

A novel method to identify hub pathways of rheumatoid arthritis based on differential pathway networks

Shi‑Tong Wei, Yong‑Hua Sun, Shi‑Hua Zong
Pages: 3187-3193
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Overexpression of NAC1 confers drug resistance via HOXA9 in colorectal carcinoma cells

Tongfa Ju, Huicheng Jin, Rongchao Ying, Qi Xie, Chunhua Zhou, Daquan Gao
Pages: 3194-3200
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Effects of neuritin on the differentiation of bone marrow‑derived mesenchymal stem cells into neuron‑like cells

Jingling Zhu, Pingping Meng, Qian Wang, Haiyan Wang, Jinli Zhang, Yuanyuan Li, Dongzheng Li, Xiaohua Tan, Lei Yang, Jin Huang
Pages: 3201-3207
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Altered expression of microRNA-98 in IL-1β-induced cartilage degradation and its role in chondrocyte apoptosis Corrigendum in /10.3892/mmr.2018.8794

Jing Wang, Lingqing Chen, Song Jin, Jun Lin, Hongmei Zheng, Hong Zhang, Hongtao Fan, Fang He, Sha Ma, Qin Li
Pages: 3208-3216
Published online on: 17 July 2017

  • View Full Article Download
Article Open Access

Hypothermia exerts early neuroprotective effects involving protein conjugation of SUMO‑2/3 in a rat model of middle cerebral artery occlusion

Gang Li, Xiaozhi Liu, Zhiguo Su, Dong Zhang
Pages: 3217-3223
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Association between TNFSF4 and BLK gene polymorphisms and susceptibility to allergic rhinitis

Yang Shen, Yun Liu, Xiao‑Qiang Wang, Xia Ke, Hou‑Yong Kang, Su‑Ling Hong
Pages: 3224-3232
Published online on: 12 July 2017

  • View Full Article Download
Article Open Access

Concurrent administration of thyroxine and donepezil induces plastic changes in the prefrontal cortex of adult hypothyroid rats

Fen Wang, Zhangbi Wu, Xiaoxue Zha, Yaojun Cai, Bo Wu, Xuemei Jia, Defa Zhu
Pages: 3233-3241
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

Roles of miR‑4463 in H2O2‑induced oxidative stress in human umbilical vein endothelial cells

Xueqin Wang, Xuemei He, Xian Deng, Yanzheng He, Xiangyu Zhou
Pages: 3242-3252
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Classifier of cross talk genes predicts the prognosis of hepatocellular carcinoma

Xiaofeng Zhai, Qingfeng Xue, Qun Liu, Yuyu Guo, Zhe Chen
Pages: 3253-3261
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Upregulation of connexin 43 and apoptosis‑associated protein expression by high glucose in H9c2 cells was improved by resveratrol via the autophagy signaling pathway

Guang‑Yu Wang, Ya‑Guang Bi, Xiang‑Dong Liu, Jun‑Feng Han, Meng Wei, Qing‑Yong Zhang
Pages: 3262-3268
Published online on: 12 July 2017

  • View Full Article Download
Article Open Access

Astragaloside IV protects against apoptosis in human degenerative chondrocytes through autophagy activation

Jianhong Liu, Qinggang Meng, Hanguang Jing, Sheng Zhou
Pages: 3269-3275
Published online on: 14 July 2017

  • View Full Article Download
Article Open Access

The atrophy of white and gray matter volume in patients with comitant strabismus: Evidence from a voxel-based morphometry study

Jun Ouyang, Lu Yang, Xin Huang, Yu-Lin Zhong, Pei-Hong Hu, Ying Zhang, Chong-Gang Pei, Yi Shao
Pages: 3276-3282
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

STIM1 silencing inhibits the migration and invasion of A549 cells

Yadong Wang, Haiyu Wang, Teng Pan, Li Li, Jiangmin Li, Haiyan Yang
Pages: 3283-3289
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Low‑dose halofuginone inhibits the synthesis of type I collagen without influencing type II collagen in the extracellular matrix of chondrocytes

Zeng Li, Hao Fei, Zhen Wang, Tianyi Zhu
Pages: 3290-3298
Published online on: 15 July 2017

  • View Full Article Download
Article Open Access

Gene microarray analysis of expression profiles in liver ischemia and reperfusion

Xiaoyang Zheng, Huaqiang Zhou, Zeting Qiu, Shaowei Gao, Zhongxing Wang, Liangcan Xiao
Pages: 3299-3307
Published online on: 13 July 2017

  • View Full Article Download
Article Open Access

BMP-7 enhances SnoN mRNA expression in renal tubular epithelial cells under high-glucose conditions

Yuanyuan Wang, Ying Xiao, Shuang Li, Lei Shi, Lirong Liu, Yingying Zhang, Mingjun Shi, Bing Guo
Pages: 3308-3314
Published online on: 17 July 2017

  • View Full Article Download
Article Open Access

mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway

Haixiang Zheng, Yucai Fu, Yusheng Huang, Xinde Zheng, Wei Yu, Wei Wang
Pages: 3315-3323
Published online on: 18 July 2017

  • View Full Article Download
Article

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction

Masashi Nakagawa, Takahiko Naruko, Kenichi Sugioka, Chizuko Kitabayashi, Nobuyuki Shirai, Masahiko Takagi, Minoru Yoshiyama, Masahiko Ohsawa, Makiko Ueda
Pages: 3324-3330
Published online on: 18 July 2017

  • View Full Article Download
Article

SIRT1 activation inhibits hyperglycemia-induced apoptosis by reducing oxidative stress and mitochondrial dysfunction in human endothelial cells

Shengqiang Wang, Jian Wang, Airong Zhao, Jigang Li
Pages: 3331-3338
Published online on: 17 July 2017

  • View Full Article Download
Article

Protective effects of marrubiin improve endometriosis through suppression of the expression of RANTES

Xiao‑Hong Sun
Pages: 3339-3344
Published online on: 14 July 2017

  • View Full Article Download
Article

Bioinformatic analysis of computational identified differentially expressed genes in tumor stoma of pregnancy‑associated breast cancer

Qian Zhou, Erhu Sun, Lijun Ling, Xiaofeng Liu, Min Zhang, Hong Yin, Cheng Lu
Pages: 3345-3350
Published online on: 12 July 2017

  • View Full Article Download
Article

A systematic study of Girdin on cell proliferation, migration and angiogenesis in different breast cancer subtypes

Hongbin Wang, Jiajun Zhang, Ming Zhang, Li Wei, Hong Chen, Zhigao Li
Pages: 3351-3356
Published online on: 14 July 2017

  • View Full Article Download
Article

Identification of microRNAs in acute respiratory distress syndrome based on microRNA expression profile in rats

Yinghui Guan, Xiang Jin, Xingang Liu, Yuanping Huang, Man Wang, Xiaodan Li
Pages: 3357-3362
Published online on: 12 July 2017

  • View Full Article Download
Article

Cytisine induces apoptosis of HepG2 cells

Lei Yu, Xin Wang, Zhi‑Feng Chen, Bo Jiang, Dong‑Yu Shang, Yong‑Xue Sun, Jing‑Hui Yang, Lian‑Fang Zhang, Yu‑Bin Ji
Pages: 3363-3370
Published online on: 14 July 2017

  • View Full Article Download
Article

Analysis of gene expression profile microarray data in complex regional pain syndrome

Wulin Tan, Yiyan Song, Chengqiang Mo, Shuangjian Jiang, Zhongxing Wang
Pages: 3371-3378
Published online on: 12 July 2017

  • View Full Article Download
Article

MicroRNA‑139 suppressed tumor cell proliferation, migration and invasion by directly targeting HDGF in epithelial ovarian cancer

Junli Liu, Shuangling Jin, Rui Wang
Pages: 3379-3386
Published online on: 12 July 2017

  • View Full Article Download
Article

Effect of CCL2 siRNA on proliferation and apoptosis in the U251 human glioma cell line Retraction in /10.3892/mmr.2023.13124

Bin Lu, Yue Zhou, Zhongzhou Su, Ai Yan, Peng Ding
Pages: 3387-3394
Published online on: 15 July 2017

  • View Full Article Download
Article

Anti‑lung cancer effect of glucosamine by suppressing the phosphorylation of FOXO

Zhanwu Yu, Yinghua Ju, Hongxu Liu
Pages: 3395-3400
Published online on: 14 July 2017

  • View Full Article Download
Article

Correlation between secreted protein acidic and rich in cysteine protein expression and the prognosis of postoperative patients exhibiting esophageal squamous cell carcinoma

Jian Wu, Jin‑Rong Zhang, Xue‑Qiu Jiang, Xu‑Guang Cao
Pages: 3401-3406
Published online on: 12 July 2017

  • View Full Article Download
Article

Coronin 3 negatively regulates G6PC3 in HepG2 cells, as identified by label‑free mass‑spectrometry

Yunzhen Gao, Ling Li, Xiaohua Xing, Minjie Lin, Yongyi Zeng, Xiaolong Liu, Jingfeng Liu
Pages: 3407-3414
Published online on: 15 July 2017

  • View Full Article Download
Article

Expression of IRAK‑3 is associated with colitis‑associated tumorigenesis in mice

Dingting Xu, Hanyun Zhang, Xiaoying Wang, Yan Chen
Pages: 3415-3420
Published online on: 12 July 2017

  • View Full Article Download
Article

Glucagon-like peptide-1 analogue liraglutide ameliorates atherogenesis via inhibiting advanced glycation end product-induced receptor for advanced glycosylation end product expression in apolipoprotein-E deficient mice

Peicheng Li, Zhaosheng Tang, Lin Wang, Bo Feng
Pages: 3421-3426
Published online on: 14 July 2017

  • View Full Article Download
Article

Chronic administration of SUMO‑1 has negative effects on novel object recognition memory as well as cell proliferation and neuroblast differentiation in the mouse dentate gyrus

Dae Young Yoo, Dae Won Kim, Hyun Jung Kwon, Hyo Young Jung, Sung Min Nam, Jong Whi Kim, Jin Young Chung, Moo‑Ho Won, Yeo Sung Yoon, Soo Young Choi, In Koo Hwang
Pages: 3427-3432
Published online on: 12 July 2017

  • View Full Article Download
Case Report

Molecular‑cytogenetic study of de novo mosaic karyotype 45,X/46,X,i(Yq)/46,X,idic(Yq) in an azoospermic male: Case report and literature review

Yuting Jiang, Ruixue Wang, Linlin Li, Lintao Xue, Shu Deng, Ruizhi Liu
Pages: 3433-3438
Published online on: 14 July 2017

  • View Full Article Download
Article

Prediction and identification of B‑cell epitopes for tumor necrosis factor‑α

Jun Zhang, Ying Cui, Yinfang Wu, Huiju Wang, Jinjing Ke
Pages: 3439-3444
Published online on: 15 July 2017

  • View Full Article Download
Article

Elevated fibrinogen‑like protein 2 in TNBS‑induced colitis mice: Association with Th17 and regulatory T cells

Haihua Lin, Renpin Chen, Xuepei Jiang, Xiaoli Wu, Xielin Huang, Xiuli Dong, Xu Yang, Xiuqing Lin, Xin Chen, Xiangrong Chen, Zhiming Huang
Pages: 3445-3454
Published online on: 15 July 2017

  • View Full Article Download
Article

Angiotensin‑(1‑7) attenuates caerulein‑induced pancreatic acinar cell apoptosis

Lijian Cui, Ruixia Liu, Chunyun Li, Xiaozheng Yu, Xiaoya Liu, Fei Hou, Cheng Chi, Chenghong Yin, Chao Wang
Pages: 3455-3460
Published online on: 14 July 2017

  • View Full Article Download
Article

Role of quercetin in protecting ARPE‑19 cells against H2O2‑induced injury via nuclear factor erythroid 2 like 2 pathway activation and endoplasmic reticulum stress inhibition

Sisi Weng, Lei Mao, Yuanyuan Gong, Tao Sun, Qing Gu
Pages: 3461-3468
Published online on: 13 July 2017

  • View Full Article Download
Article

Suppression of TAFI by siRNA inhibits invasion and migration of breast cancer cells

Chao Yu, Yun Luan, Zejun Wang, Jingjie Zhao, Chengwei Xu
Pages: 3469-3474
Published online on: 18 July 2017

  • View Full Article Download
Article

Dihydroartemisinin and gefitinib synergistically inhibit NSCLC cell growth and promote apoptosis via the Akt/mTOR/STAT3 pathway

Hong Jin, Ai‑Ying Jiang, Han Wang, Yong Cao, Yan Wu, Xiao‑Feng Jiang
Pages: 3475-3481
Published online on: 14 July 2017

  • View Full Article Download
Article

Involvement of gut microbiota in the association between gastrointestinal motility and 5‑HT expression/M2 macrophage abundance in the gastrointestinal tract

Mo Yang, Hirokazu Fukui, Hirotsugu Eda, Yoshitaka Kitayama, Ken Hara, Mio Kodani, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroto Miwa
Pages: 3482-3488
Published online on: 12 July 2017

  • View Full Article Download
Article

Inhibition of p38MAPK potentiates mesenchymal stem cell therapy against myocardial infarction injury in rats

Zhiling Zhang, Shulan Zhou, Zhiliang Mei, Ming Zhang
Pages: 3489-3493
Published online on: 14 July 2017

  • View Full Article Download
Article

Platelet poor plasma gel combined with amnion improves the therapeutic effects of human umbilical cord‑derived mesenchymal stem cells on wound healing in rats

Lujun Yang, Jie Ma, Saiyang Gan, Shuli Chu, Martin Maldonado, Jianda Zhou, Lian Ma, Shijie Tang
Pages: 3494-3502
Published online on: 13 July 2017

  • View Full Article Download
Article

Downregulation of AQP2 in the anterior vaginal wall is associated with the pathogenesis of female stress urinary incontinence

Zujuan Zhang, Pan Xu, Zhenwei Xie, Fengxian Shen, Ning Chen, Liming Yu, Ronghuan He
Pages: 3503-3509
Published online on: 15 July 2017

  • View Full Article Download
Article

Effects of age on biological and functional characterization of adipose‑derived stem cells from patients with end‑stage liver disease

Yanyu Jin, Lei Yang, Yanyan Zhang, Wei Gao, Zhi Yao, Yang Song, Yuliang Wang
Pages: 3510-3518
Published online on: 13 July 2017

  • View Full Article Download
Article

HO‑1 alleviates cholesterol‑induced oxidative stress through activation of Nrf2/ERK and inhibition of PI3K/AKT pathways in endothelial cells

Xiaohan Jin, Zhongwei Xu, Rong Fan, Chengyan Wang, Wenjie Ji, Yongqiang Ma, Wei Cai, Yan Zhang, Ning Yang, Shuang Zou, Xin Zhou, Yuming Li
Pages: 3519-3527
Published online on: 13 July 2017

  • View Full Article Download
Article

TcpC secreting uropathogenic E. coli promoted kidney cells to secrete MIP-2 via p38 MAPK pathway

Yujie He, Jie Fang, Chong Zhang, Jun Pan, Qi Jin, Yingzhi Yang, Linyao Wang, Baoming Wang, Dayong Zhang, Jianping Pan
Pages: 3528-3534
Published online on: 17 July 2017

  • View Full Article Download
Article

A dichloromethane fraction of Triticum aestivum sprouts reduces allergic immune response through inhibiting Th2 differentiation in ovalbumin‑immunized mice

Hyeon‑Hui Ki, Sung‑Woo Hwang, Ji‑Hyun Lee, Young‑Ho Kim, Dae‑Ki Kim, Young‑Mi Lee
Pages: 3535-3541
Published online on: 15 July 2017

  • View Full Article Download
Article

Epigallocatechin gallate attenuates overload‑induced cardiac ECM remodeling via restoring T cell homeostasis

Yongsheng Han, Qingtong Wang, Xizhen Fan, Jun Chu, Junfu Peng, Yousheng Zhu, Yan Li, Xiaojing Li, Lei Shen, James Asenso, Shanfeng Li
Pages: 3542-3550
Published online on: 15 July 2017

  • View Full Article Download
Article

NLRC5 silencing ameliorates cardiac fibrosis by inhibiting the TGF‑β1/Smad3 signaling pathway

Hongtao Zhou, Xuefang Yu, Guiming Zhou
Pages: 3551-3556
Published online on: 14 July 2017

  • View Full Article Download
Article

MicroRNA-219 is downregulated in non-small cell lung cancer and inhibits cell growth and metastasis by targeting HMGA2 Retraction in /10.3892/mmr.2024.13237

Xiaoping Sun, Min Xu, Haiyan Liu, Kunxiu Ming
Pages: 3557-3564
Published online on: 15 July 2017

  • View Full Article Download
Article

MicroRNA‑302a suppresses cell proliferation, migration and invasion in osteosarcoma by targeting ADAM9

Xiaoming Yang, Yan Cui, Fuqiang Yang, Chao Sun, Xuejian Gao
Pages: 3565-3572
Published online on: 14 July 2017

  • View Full Article Download
Article

KDM5A promotes proliferation and EMT in ovarian cancer and closely correlates with PTX resistance

Tongfu Feng, Yan Wang, Yan Lang, Yuanzhen Zhang
Pages: 3573-3580
Published online on: 12 July 2017

  • View Full Article Download
Article

Melittin exerts an antitumor effect on non‑small cell lung cancer cells

Su‑Fang Zhang, Zhe Chen
Pages: 3581-3586
Published online on: 14 July 2017

  • View Full Article Download
Article

Hydrogen sulfide prevents homocysteine‑induced endoplasmic reticulum stress in PC12 cells by upregulating SIRT‑1

Chun‑Yan Wang, Wei Zou, Xiao‑Yu Liang, Zhi‑Sheng Jiang, Xiang Li, Hai‑Jun Wei, Yi‑Yun Tang, Ping Zhang, Xiao‑Qing Tang
Pages: 3587-3593
Published online on: 15 July 2017

  • View Full Article Download
Article

Knockdown of JARID2 inhibits the viability and migration of placenta trophoblast cells in preeclampsia

Yatao Jiang, Yuqing Chen, Yanping Chen
Pages: 3594-3599
Published online on: 15 July 2017

  • View Full Article Download
Article

Knockdown of JARID2 inhibits the proliferation and invasion of ovarian cancer through the PI3K/Akt signaling pathway

Jian Cao, Huiling Li, Guangquan Liu, Suping Han, Pengfei Xu
Pages: 3600-3605
Published online on: 17 July 2017

  • View Full Article Download
Article

MicroRNA‑130a inhibits growth and metastasis of osteosarcoma cells by directly targeting ZEB1 Retraction in /10.3892/mmr.2022.12756

Lankai Yi, Meixiu Liu, Zhiliang Tang
Pages: 3606-3612
Published online on: 13 July 2017

  • View Full Article Download
Article

MicroRNA-300 decreases cell viability, inhibits migration and promotes apoptosis of osteosarcoma cells via downregulation of Twist1

Jinpeng Jia, Pei Yin, Gang Han, Meng Xu, Wei Wang, Wenzhi Bi
Pages: 3613-3618
Published online on: 17 July 2017

  • View Full Article Download
Article

Exogenous spermine preserves mitochondrial bioenergetics via regulating Src kinase signaling in the spinal cord

Rui Zhang, Xin‑Nan Ma, Kai Liu, Lei Zhang, Meng Yao
Pages: 3619-3626
Published online on: 18 July 2017

  • View Full Article Download
Article

Magnesium isoglycyrrhizinate protects against renal‑ischemia‑reperfusion injury in a rat model via anti‑inflammation, anti‑oxidation and anti‑apoptosis

Zhigang Zhao, Zhongzhi Tang, Wenkai Zhang, Jie Liu, Bo Li
Pages: 3627-3633
Published online on: 15 July 2017

  • View Full Article Download
Article

miR‑140‑5p inhibits human glioma cell growth and invasion by targeting JAG1

Huan‑Li Yang, Ya‑Mei Gao, Jin‑An Zhao
Pages: 3634-3640
Published online on: 12 July 2017

  • View Full Article Download
Article

ATF3 promotes migration and M1/M2 polarization of macrophages by activating tenascin‑C via Wnt/β‑catenin pathway

Hao Sha, Dianzhong Zhang, Yunfei Zhang, Yanhua Wen, Yucai Wang
Pages: 3641-3647
Published online on: 14 July 2017

  • View Full Article Download
Article

AMPK activation restores ischemic post‑conditioning cardioprotection in STZ‑induced type 1 diabetic rats: Role of autophagy

Bin Zhou, Yan Leng, Shao‑Qing Lei, Zhong‑Yuan Xia
Pages: 3648-3656
Published online on: 18 July 2017

  • View Full Article Download
Article

Ginkgo biloba extract prevents acute myocardial infarction and suppresses the inflammation‑ and apoptosis‑regulating p38 mitogen‑activated protein kinases, nuclear factor‑κB and B‑cell lymphoma 2 signaling pathways

Yanping Li, Ya Zhang, Min Wen, Ju Zhang, Xia Zhao, Yuan Zhao, Jiagang Deng
Pages: 3657-3663
Published online on: 15 July 2017

  • View Full Article Download
Article

MicroRNA‑455 is downregulated in gastric cancer and inhibits cell proliferation, migration and invasion via targeting insulin‑like growth factor 1 receptor

Shan Zhang, Wan‑Ling Yin, Xin Zhang, Xiao‑Yu Zhang
Pages: 3664-3672
Published online on: 14 July 2017

  • View Full Article Download
Article

MDG‑1 inhibits H2O2‑induced apoptosis and inflammation in human umbilical vein endothelial cells

Luo‑Cheng Li, Zhi‑Wei Wang, Xiao‑Ping Hu, Zhi‑Yong Wu, Zhi‑Peng Hu, Yong‑Le Ruan
Pages: 3673-3679
Published online on: 12 July 2017

  • View Full Article Download
Article

Imaging characteristics of adult onset Still's disease demonstrated with 18F-FDG PET/CT

Lei Jiang, Yan Xiu, Taoying Gu, Caihong Dong, Bing Wu, Hongcheng Shi
Pages: 3680-3686
Published online on: 17 July 2017

  • View Full Article Download
Article

LncRNA H19 regulates ID2 expression through competitive binding to hsa-miR-19a/b in acute myelocytic leukemia

Tong‑Feng Zhao, Hui‑Zhen Jia, Zhen‑Zhen Zhang, Xiao‑Su Zhao, Yan‑Fen Zou, Wei Zhang, Jun Wan, Xiao‑Fan Chen
Pages: 3687-3693
Published online on: 18 July 2017

  • View Full Article Download
Article

Down-regulation of long noncoding RNA RP11-713B9.1 contributes to the cell viability in non‑small cell lung cancer (NSCLC)

Jun Cai, Xuan Wang, Hu Huang, Meng Wang, Zhihong Zhang, Yan Hu, Shihua Yu, Yonghua Yang, Jiyuan Yang
Pages: 3694-3700
Published online on: 17 July 2017

  • View Full Article Download
Journal Cover
January-2026 Volume 33 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

  • View Full Article Download
Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

  • View Full Article Download
Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

  • View Full Article Download
Article Open Access

Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

  • View Full Article Download
Review Open Access

Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

  • View Full Article Download
Article Open Access

Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

  • View Full Article Download
Review Open Access

Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

  • View Full Article Download
Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

  • Purchase Full Text Article Purchase Download
Review Open Access

Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

  • View Full Article Download
Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

  • View Full Article Download
Article Open Access

Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

  • View Full Article Download
Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

  • Purchase Full Text Article Purchase Download
Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

  • View Full Article Download
Article Open Access

Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

  • View Full Article Download
Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

  • View Full Article Download
Review Open Access

Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

  • View Full Article Download
Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 33 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

  • Download
Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

  • Download
Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

  • Purchase Download
Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

  • Download
Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

  • Download
Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

  • Download
Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

  • Download
Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

  • Download
Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

  • Download
Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

  • View Full Article Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team