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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2019 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review)

Xiang Shi, Jingjing Wang, Yu Lei, Caofan Cong, Dailin Tan, Xianrong Zhou
Pages: 4529-4535
Published online on: 03 April 2019

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Article Open Access

The 15d‑PGJ2 hydrogel ameliorates atopic dermatitis through suppression of the immune response

Marcelo H. Napimoga, Juliana T. Clemente‑Napimoga, Nina M. Machabanski, Maria Eduarda A. Juliani, Pedro Henrique B. C. Acras, Cristina G. Macedo, Henrique B. Abdalla, Antônio José de Pinho , Andresa B. Soares, Marcelo Sperandio, Daniele R. de Araújo
Pages: 4536-4544
Published online on: 11 April 2019

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Article Open Access

Zinc finger E‑box binding homeobox 2 functions as an oncogene in human laryngeal squamous cell carcinoma

Qun Li, Liang Ma, Zhenhua Wu, Guoli Wang, Qi Huang, Zhisen Shen, Rui Yu
Pages: 4545-4552
Published online on: 04 April 2019

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Article Open Access

Alamandine attenuates long‑term hypertension‑induced cardiac fibrosis independent of blood pressure

Lan Wang, Chi Liu, Xiru Chen, Peng Li
Pages: 4553-4560
Published online on: 15 April 2019

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Article Open Access

MicroRNA‑195‑5p inhibitor prevents the development of osteoarthritis by targeting REGγ

Yang Shu, Junpeng Long, Weixiong Guo, Wei Ye
Pages: 4561-4568
Published online on: 03 April 2019

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Article Open Access

Effects of granulocyte colony‑stimulating factor on rabbit carotid and porcine heart models of chronic obliterative arterial disease

Zhaohui Hu, Zhisong Chen, Yiping Wang, Jinfa Jiang, Gary Tse, Wenjun Xu, Junbo Ge, Bing Sun
Pages: 4569-4578
Published online on: 03 April 2019

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Article Open Access

YB1 protects cardiac myocytes against H2O2‑induced injury via suppression of PIAS3 mRNA and phosphorylation of STAT3

Shiqi Wang, Fuwei He, Zhenwei Li, Yewen Hu, Ning Huangfu, Xiaomin Chen
Pages: 4579-4588
Published online on: 03 April 2019

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Article Open Access

Quercetin suppresses glomerulosclerosis and TGF‑β signaling in a rat model

Yifan Liu, Enlai Dai, Jing Yang
Pages: 4589-4596
Published online on: 03 April 2019

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Article Open Access

Decreased expression of ubiquilin‑1 following neonatal hypoxia‑ischemic brain injury in mice

Li Luo, Yilin Liu, Xing Tu, Xuxin Ren, Wenyan Zhao, Jing Liu, Li Zhang, Weiqiang Chen, Pei Zhang, Weicai Wang, Lanhai Lü, Mengxia Wang
Pages: 4597-4602
Published online on: 15 April 2019

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Article Open Access

Hypercholesterolaemia increases the risk of high‑turnover osteoporosis in men

Yanman Zhou, Tuo Deng, Haiqing Zhang, Qingbo Guan, Hongqiang Zhao, Chunxiao Yu, Shanshan Shao, Meng Zhao, Jin Xu
Pages: 4603-4612
Published online on: 04 April 2019

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Article Open Access

Long noncoding RNA STCAT16 suppresses cell growth and its expression predicts prognosis in patients with gastric cancer

Jian‑Feng Zhang, Wei Jiang, Qian‑Feng Zhang, Xiao‑Ling Kuai, Zhen‑Biao Mao, Zhi‑Wei Wang
Pages: 4613-4622
Published online on: 04 April 2019

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Article Open Access

Proliferation of human hepatocellular carcinoma cells from surgically resected specimens under conditionally reprogrammed culture

Zhenglu Wang, Bowen Bi, Hongli Song, Lei Liu, Hong Zheng, Shusen Wang, Zhongyang Shen
Pages: 4623-4630
Published online on: 12 April 2019

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Article Open Access

Prediction of IER5 structure and function using a bioinformatics approach

Qiang Xiong, Xiaoyan Jiang, Xiaodan Liu, Pingkun Zhou, Kuke Ding
Pages: 4631-4636
Published online on: 15 April 2019

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Article Open Access

Arbutin promotes MC3T3‑E1 mouse osteoblast precursor cell proliferation and differentiation via the Wnt/β‑catenin signaling pathway

Xiangji Man, Liyu Yang, Shengye Liu, Lei Yang, Mingyang Li, Qin Fu
Pages: 4637-4644
Published online on: 04 April 2019

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Article Open Access

Low‑intensity pulsed ultrasound promotes apoptosis and inhibits angiogenesis via p38 signaling‑mediated endoplasmic reticulum stress in human endothelial cells

Zhongping Su, Tianhua Xu, Yaqing Wang, Xiasheng Guo, Juan Tu, Dong Zhang, Xiangqing Kong, Yanhui Sheng, Wei Sun
Pages: 4645-4654
Published online on: 05 April 2019

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Article Open Access

MicroRNA‑144‑3p may participate in the pathogenesis of preeclampsia by targeting Cox‑2

Suwei Hu, Jie Li, Ming Tong, Qian Li, Yong Chen, Hongmei Lu, Yixiong Wang, Lingfeng Min
Pages: 4655-4662
Published online on: 11 April 2019

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Article Open Access

lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis

Chuan Cui, Xing Wang, Xiao‑Ming Shang, Li Li, Yi Ma, Guo‑Yu Zhao, Yu‑Xin Song, Xue‑Bin Geng, Bi‑Qiong Zhao, Mei‑Rong Tian, Hong‑Ling Wang
Pages: 4663-4672
Published online on: 05 April 2019

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Article Open Access

Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OA‑treated HepG2 cells

Yayun Liu, Lu Liao, Yong Chen, Fengmei Han
Pages: 4673-4684
Published online on: 05 April 2019

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Article Open Access

Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma

Qing Luo, Meng Cui, Qinfu Deng, Jinbo Liu
Pages: 4685-4696
Published online on: 05 April 2019

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Article Open Access

Comprehensive analysis of the aberrantly expressed lncRNA‑associated ceRNA network in breast cancer

Tayier Tuersong, Linlin Li, Zumureti Abulaiti, Shumei Feng
Pages: 4697-4710
Published online on: 15 April 2019

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Case Report Open Access

Novel variants in the KERA gene cause autosomal recessive cornea plana in a Chinese family: A case report

Chengzi Huang, Xigui Long, Can Peng, Pengsiyuan Lin, Hu Tan, Weigang Lv, Lingqian Wu
Pages: 4711-4718
Published online on: 11 April 2019

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Article Open Access

Effects of leukemia inhibitory factor receptor on the adipogenic differentiation of human bone marrow mesenchymal stem cells

Tao Wang, Ruiqiao Yan, Xiaoyuan Xu, Huan Yu, Jianfang Wu, Yaofang Yang, Weidong Li
Pages: 4719-4726
Published online on: 08 April 2019

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Article Open Access

Effect of integrin β1 in the treatment of stress urinary incontinence by electrical stimulation

Yang Li, Bing‑Shu Li, Cheng Liu, Sha‑Sha Hong, Jie Min, Ming Hu, Jian‑Ming Tang, Su‑Ting Li, Ting‑Ting Wang, Hui‑Xin Zhou, Li Hong
Pages: 4727-4734
Published online on: 10 April 2019

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Article Open Access

Dysregulated long non‑coding RNAs in pleomorphic adenoma tissues of pleomorphic adenoma gene 1 transgenic mice

Wanlin Xu, Limin Liu, Hao Lu, Jinye Fu, Chenping Zhang, Wenjun Yang, Shukun Shen
Pages: 4735-4742
Published online on: 11 April 2019

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Article Open Access

Interleukin‑17A facilitates osteoclast differentiation and bone resorption via activation of autophagy in mouse bone marrow macrophages

Lu Song, Jingyi Tan, Zhongxiu Wang, Peihui Ding, Qi Tang, Mengjiao Xia, Yingming Wei, Lili Chen
Pages: 4743-4752
Published online on: 11 April 2019

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Article Open Access

Astaxanthin inhibits homocysteine‑induced endothelial cell dysfunction via the regulation of the reactive oxygen species‑dependent VEGF‑VEGFR2‑FAK signaling pathway

Xian‑Jun Wang, Da‑Chen Tian, Feng‑Wen Wang, Meng‑Hao Zhang, Cun‑Dong Fan, Wang Chen, Mei‑Hong Wang, Xiao‑Yan Fu, Jin‑Kui Ma
Pages: 4753-4760
Published online on: 12 April 2019

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Article Open Access

Overexpression of CKS2 is associated with a poor prognosis and promotes cell proliferation and invasion in breast cancer

Naiqi Huang, Zuli Wu, Hong Hong, Xiangming Wang, Fengqiang Yang, Hengguo Li
Pages: 4761-4769
Published online on: 05 April 2019

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Article Open Access

A novel resveratrol analog PA19 attenuates obesity‑induced cardiac and renal injury by inhibiting inflammation and inflammatory cell infiltration

Wenxin Zhang, Hongjin Chen, Chuchu Sun, Beibei Wu, Bin Bai, Hui Liu, Xiaoou Shan, Guang Liang, Yali Zhang
Pages: 4770-4778
Published online on: 12 April 2019

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Article Open Access

miRNA‑15a‑5p facilitates the bone marrow stem cell apoptosis of femoral head necrosis through the Wnt/β‑catenin/PPARγ signaling pathway

Wan‑Li Zhang, Cheng‑Tao Chi, Xiang‑Hui Meng, Shao‑Dong Liang
Pages: 4779-4787
Published online on: 04 April 2019

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Article Open Access

Novel agent #2714 potently inhibits lung cancer growth by suppressing cell proliferation and by inducing apoptosis in vitro and in vivo

Wenjie Lu, Qianqian Sun, Bo Chen, Yan Li, Youzhi Xu, Siying Wang
Pages: 4788-4796
Published online on: 02 April 2019

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Article Open Access

Exosomes derived from mangiferin‑stimulated perivascular adipose tissue ameliorate endothelial dysfunction

Qianwen Zhao, Jie Yang, Baolin Liu, Fang Huang, Yuehua Li
Pages: 4797-4805
Published online on: 04 April 2019

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Article Open Access

Signature microRNAs and long noncoding RNAs in laryngeal cancer recurrence identified using a competing endogenous RNA network

Zhengyi Tang, Ganguan Wei, Longcheng Zhang, Zhiwen Xu
Pages: 4806-4818
Published online on: 10 April 2019

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Article Open Access

miR‑27b‑3p and miR‑607 cooperatively regulate BLM gene expression by directly targeting the 3'‑UTR in PC3 cells

Yinglian Chen, Jiafu Zhao, Zhiqiang Duan, Ting Gong, Wei Chen, Sainan Wang, Houqiang Xu
Pages: 4819-4831
Published online on: 05 April 2019

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Article Open Access

Altered brain activity in patients with strabismus and amblyopia detected by analysis of regional homogeneity: A resting‑state functional magnetic resonance imaging study

Yi Shao, Qing‑Hai Li, Biao Li, Qi Lin, Ting Su, Wen‑Qing Shi, Pei‑Wen  Zhu, Qing Yuan, Yong‑Qiang Shu, Ying He, Wen‑Feng Liu, Lei Ye
Pages: 4832-4840
Published online on: 10 April 2019

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Article Open Access

Triptolide inhibits migration and proliferation of fibroblasts from ileocolonic anastomosis of patients with Crohn's disease via regulating the miR‑16‑1/HSP70 pathway Retraction in /10.3892/mmr.2025.13549

Min Chen, Jin‑Min Wang, Dong Wang, Rong Wu, Hong‑Wei Hou
Pages: 4841-4851
Published online on: 03 April 2019

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Article Open Access

Overexpression of COX6B1 protects against I/R‑induced neuronal injury in rat hippocampal neurons

Shan Yang, Peng Wu, Jianwen Xiao, Li Jiang
Pages: 4852-4862
Published online on: 10 April 2019

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Article Open Access

Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death

Yanwen Jia, Shengqun Jiang, Chen Chen, Guohua Lu, Yang Xie, Xincheng Sun, Liqin Huang
Pages: 4863-4871
Published online on: 11 April 2019

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Article Open Access

Paroxysmal spasticity of lower extremities as the initial symptom in two siblings with maple syrup urine disease

Yi‑Dan Liu, Xu Chu, Rui‑Hua Liu, Ying Sun, Qing‑Xia Kong, Qiu‑Bo Li
Pages: 4872-4880
Published online on: 05 April 2019

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Article Open Access

High expression of DLC family proteins predicts better prognosis and inhibits tumor progression in NSCLC

Li Sun, Jing Sun, Jun‑Ding Song
Pages: 4881-4889
Published online on: 10 April 2019

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Article Open Access

Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway

Bing Bao, Man‑Qing Zhang, Zhi‑Ying Chen, Xiang‑Bing Wu, Zhong‑Bing Xia, Jing‑Yan Chai, Xiao‑Ping Yin
Pages: 4890-4896
Published online on: 10 April 2019

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Article Open Access

Endophilin 1 knockdown prevents synaptic dysfunction induced by oligomeric amyloid β

Yichen Yin, Caihui Cha, Fengming Wu, Jiong Li, Sumei Li, Xiaonan Zhu, Jifeng Zhang, Guoqing Guo
Pages: 4897-4905
Published online on: 12 April 2019

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Article Open Access

Comprehensive genomic and prognostic analysis of the IL‑17 family genes in lung cancer

Tingting Liao, Jinshuo Fan, Zhilei Lv, Juanjuan Xu, Feng Wu, Guanghai Yang, Qi Huang, Mengfei Guo, Guorong Hu, Mei Zhou, Limin Duan, Sufei Wang, Yang Jin
Pages: 4906-4918
Published online on: 15 April 2019

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Article

Transgelin 2 overexpression inhibits cervical cancer cell invasion and migration

Qun Zhou, Xuelu Jiang, Wei Yan, Xiaoqing Dou
Pages: 4919-4926
Published online on: 03 April 2019

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Article

Role of lncRNA uc.457 in the differentiation and maturation of cardiomyocytes

Qijun Zhang, Zijie Cheng, Zhangbin Yu, Chun Zhu, Lingmei Qian
Pages: 4927-4934
Published online on: 04 April 2019

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Article

MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells

Yue Li, Long Zhao, Yafei Qi, Xianghong Yang
Pages: 4935-4945
Published online on: 16 April 2019

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Article

miR‑210‑3p regulates cell growth and affects cisplatin sensitivity in human ovarian cancer cells via targeting E2F3

Yue Jin, Jun Wei, Shaoting Xu, Fang Guan, Lijun Yin, Haibin Zhu
Pages: 4946-4954
Published online on: 04 April 2019

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Article

Exogenous oestradiol benzoate induces male mice azoospermia through modulation of oxidative stress and testicular metabolic cooperation

Jianghua Le, Xiaocan Lei, Yanping Ren, Zhipeng Li, Haoyan Tu, Fangya Ding, Xiaodong Yi, Yi Zhou, Qingyou Liu, Shun Zhang
Pages: 4955-4963
Published online on: 16 April 2019

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Article

Salidroside suppresses the metastasis of hepatocellular carcinoma cells by inhibiting the activation of the Notch1 signaling pathway

Linlin Lu, Shousheng Liu, Quanjiang Dong, Yongning Xin
Pages: 4964-4972
Published online on: 02 April 2019

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Article

SIRT4 suppresses the PI3K/Akt/NF‑κB signaling pathway and attenuates HUVEC injury induced by oxLDL

Yu Tao, Songping Yu, Min Chao, Yang Wang, Jianhua Xiong, Hengli Lai
Pages: 4973-4979
Published online on: 12 April 2019

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Article

Expression and potential regulation of miRNA‑431 during lung development of Sprague‑Dawley rats

Zhong‑Yi Sun, Yan‑Qing Shen, Xiao‑Qing Chen, Xiao‑Yu Zhou, Rui Cheng, Zhi‑Dan Bao, Yang Yang
Pages: 4980-4988
Published online on: 11 April 2019

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Article

Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of α‑synuclein methylation

Qing Zhao, Hui Liu, Jiwei Cheng, Yudan Zhu, Qian Xiao, Yu Bai, Jie Tao
Pages: 4989-4997
Published online on: 11 April 2019

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Article

Long noncoding RNA PURPL promotes cell proliferation in liver cancer by regulating p53

Xueyan Fu, Yawei Wang, Gang Wu, Wanchuan Zhang, Shaolin Xu, Wenqing Wang
Pages: 4998-5006
Published online on: 12 April 2019

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Article

(3R)‑5,6,7‑trihydroxy‑3‑isopropyl‑3‑methylisochroman‑1‑one attenuates cardiac dysfunction via the apelin/APJ signaling pathway

Mei Ding, Lianyue Guan, Chunmei Zhang, Ping Yang, Hailing Yang
Pages: 5007-5014
Published online on: 03 April 2019

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Article

Acute exposure to 3‑deoxyglucosone at high glucose levels impairs insulin secretion from β‑cells by downregulating the sweet taste receptor signaling pathway

Xiudao Song, Guoqiang Liang, Min Shi, Liang Zhou, Fei Wang, Lurong Zhang, Fei Huang, Guorong Jiang
Pages: 5015-5022
Published online on: 15 April 2019

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Article

Downregulation of DCC sensitizes multiple myeloma cells to bortezomib treatment

Dorival Mendes Rodrigues‑Junior, Thaís Priscila Biassi, Gabriela Estrela de Albuquerque, Viviane Carlin, Marcus Vinicius Buri, Joel Machado‑Junior, Andre Luiz Vettore
Pages: 5023-5029
Published online on: 09 April 2019

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Article

Novel CLCN7 mutations cause autosomal dominant osteopetrosis type II and intermediate autosomal recessive osteopetrosis

Li Li, Shan-Shan Lv, Chun Wang, Hua Yue, Zhen-Lin Zhang
Pages: 5030-5038
Published online on: 03 April 2019

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Article

Combination of ions promotes cell migration via extracellular signal‑regulated kinase 1/2 signaling pathway in human gingival fibroblasts

Kimiko Yamaguchi‑Ueda, Yuki Akazawa, Keita Kawarabayashi, Asuna Sugimoto, Hiroshi Nakagawa, Aya Miyazaki, Rika Kurogoushi, Kokoro Iwata, Takamasa Kitamura, Aya Yamada, Tomokazu Hasegawa, Satoshi Fukumoto, Tsutomu Iwamoto
Pages: 5039-5045
Published online on: 08 April 2019

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Review Open Access

Perspectives of small molecule inhibitors of activin receptor‑like kinase in anti‑tumor treatment and stem cell differentiation (Review)

Xueling Cui, Shumi Shang, Xinran Lv, Jing Zhao, Yan Qi, Zhonghui Liu
Pages: 5053-5062
Published online on: 30 April 2019

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Article Open Access

Clinical significance of miRNA‑1 and its potential target gene network in lung squamous cell carcinoma

Xiaojiao Li, Meijiao Qin, Jiacheng Huang, Jie Ma, Xiaohua Hu
Pages: 5063-5078
Published online on: 19 April 2019

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Article Open Access

SM‑164 enhances the antitumor activity of adriamycin in human U2‑OS cells via downregulation of X‑linked inhibitor of apoptosis protein

Jiangwei Chen, Xuanyin Chen, Xiaodong Chen, Haiying Sun, Dong Yang
Pages: 5079-5086
Published online on: 22 April 2019

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Inhibitory effect of 17β‑estradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2

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Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities

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Berberine improves advanced glycation end products‑induced osteogenic differentiation responses in human periodontal ligament stem cells through the canonical Wnt/β‑catenin pathway

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CD47 deficiency protects cardiomyocytes against hypoxia/reoxygenation injury by rescuing autophagic clearance

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Changes in mitochondrial cytochrome c oxidase mRNA levels with cataract severity in lens epithelia of Japanese patients

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Pages: 5464-5472
Published online on: 02 May 2019

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January-2026 Volume 33 Issue 1

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Ayman A. Althubity
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Xingzheng Deng, Shizhang Liu, Huitong Liu
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
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Published online on: 03 November 2025

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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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