Journal Articles

Article Open Access

Expression levels of specific microRNAs are increased after exercise and are associated with cognitive improvement in Parkinson's disease

Franciele Cascaes Da Silva, Michele Patrícia Rode, Giovanna Grunewald Vietta, Rodrigo Da Rosa Iop, Tânia Beatriz Creczynski‑Pasa, Alessandra Swarowsky Martin, Rudney Da Silva

Article Number: 618 Published online on: 29 June 2021
Article Open Access

circPTPN22 as a novel biomarker and ceRNA in peripheral blood mononuclear cells of rheumatoid arthritis

Zhuyan Jiang, Zhiting Zhong, Qingqing Miao, Yue Zhang, Bing Ni, Mengjie Zhang, Jun Tang

Article Number: 617 Published online on: 29 June 2021
Article

H3K9me2 regulates early transcription factors to promote mesenchymal stem‑cell differentiation into cardiomyocytes

Xiaolin Sun, Xiang Gu, Hongxiao Li, Pei Xu, Mengting Li, Ye Zhu, Qisheng Zuo, Bichun Li

Article Number: 616 Published online on: 29 June 2021
Article

Anti‑angiogenic effect of mountain ginseng in vitro and in vivo: Comparison with farm‑cultivated ginseng

Jin Soo Kim, Jae-Myung Yoo, Jong Eel Park, Jungeun Kim, Sun-Gun Kim, Young Mi Seok, Jun-Ho Son, Hyo Jung Kim

Article Number: 615 Published online on: 29 June 2021
Article Open Access

Nuclear PKR in retinal neurons in the early stage of diabetic retinopathy in streptozotocin‑induced diabetic rats

Viviane Aline Oliveira Silva, Nayara Delgado André, Thaís Amaral E Sousa, Vâni Maria Alves, Isis Do Carmo Kettelhut, Fernando Luiz De Lucca

Article Number: 614 Published online on: 28 June 2021
Article Open Access

PI3K/AKT phosphorylation activates ERRα by upregulating PGC‑1α and PGC‑1β in gallbladder cancer

Lei Wang, Mengmeng Yang, Huihan Jin

Article Number: 613 Published online on: 28 June 2021
Article Open Access

Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis

Mangmang Chen, Lipeng Huang, Yangxun Lv, Liubing Li, Qirong Dong

Article Number: 612 Published online on: 28 June 2021
Review Open Access

Dysregulated inflammation may predispose patients with serious mental illnesses to severe COVID‑19 (Review)

Sergej Nadalin, Hrvoje Jakovac, Vjekoslav Peitl, Dalibor Karlović, Alena Buretić‑Tomljanović

Article Number: 611 Published online on: 28 June 2021
Article Open Access

Effects of Melandrium firmum Rohrbach on RANKL‑induced osteoclast differentiation and OVX rats

Minsun Kim, Jae-Hyun Kim, Sooyeon Hong, Boguen Kwon, Eun-Young Kim, Hyuk-Sang Jung, Youngjoo Sohn

Article Number: 610 Published online on: 25 June 2021
Article Open Access

Humanized anti‑TLR4 monoclonal antibody ameliorates lipopolysaccharide‑related acute kidney injury by inhibiting TLR4/NF‑κB signaling

Qiuhua Zhang, Liang Wang, Mian Wu, Xiaobin Liu, Yushan Zhu, Jin Zhu, Changying Xing

Article Number: 608 Published online on: 25 June 2021
Article Open Access

Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy‑induced osteoporosis model

Jae-Hyun Kim, Hwajeong Shin, Minsun Kim, Sangwoo Kim, Kwangchan Song, Hyuk-Sang Jung, Youngjoo Sohn

Article Number: 607 Published online on: 25 June 2021
Article

Telomere shortening and expression of TRF1 and TRF2 in uterine leiomyoma

Bong-Kyeong Oh, Yoojung Choi, Joong Sub Choi

Article Number: 606 Published online on: 24 June 2021
Review Open Access

Protective role of taurine against oxidative stress (Review)

Stella Baliou, Maria Adamaki, Petros Ioannou, Aglaia Pappa, Mihalis I. Panayiotidis, Demetrios A. Spandidos, Ioannis Christodoulou, Anthony M. Kyriakopoulos, Vassilis Zoumpourlis

Article Number: 605 Published online on: 24 June 2021
Article Open Access

M2‑like tumour‑associated macrophage‑secreted IGF promotes thyroid cancer stemness and metastasis by activating the PI3K/AKT/mTOR pathway

Juan Lv, Chao Liu, Fu-Kun Chen, Zhi-Ping Feng, Li Jia, Peng-Jie Liu, Zhi-Xian Yang, Fei Hou, Zhi-Yong Deng

Article Number: 604 Published online on: 28 June 2021
Article Open Access

Circular RNA profiling reveals a potential role of hsa_circ_IPCEF1 in papillary thyroid carcinoma

Min Guo, Yushuang Sun, Junzhu Ding, Yong Li, Sihan Yang, Yanna Zhao, Xin Jin, Shan-Shan Li

Article Number: 603 Published online on: 24 June 2021
Review Open Access

Circular RNA: A novel type of biomarker for glioma (Review)

Wei Sun, Huandi Zhou, Xuetao Han, Liubing Hou, Xiaoying Xue

Article Number: 602 Published online on: 24 June 2021
Article Open Access

Pulmonary coagulation and fibrinolysis abnormalities that favor fibrin deposition in the lungs of mouse antibody-mediated transfusion-related acute lung injury

Yunhong Yu, Peng Jiang, Pan Sun, Na Su, Fangzhao Lin

Article Number: 601 Published online on: 23 June 2021
Correction Open Access

[Corrigendum] Traditional Chinese medicine, Fuzheng Kang‑Ai decoction, inhibits metastasis of lung cancer cells through the STAT3/MMP9 pathway

Longmei Li, Sumei Wang, Xiaobin Yang, Shunqin Long, Shujing Xiao, Wanyin Wu, Swei Sunny Hann

Article Number: 600 Published online on: 25 June 2021
Retraction Open Access
Article Open Access

Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Yoshiyuki Hattori, Hiromu Saito, Teruaki Oku, Kei-Ichi Ozaki

Article Number: 598 Published online on: 23 June 2021
Article Open Access

Inhibition of lncRNA SNHG8 plays a protective role in hypoxia-ischemia-reoxygenation-induced myocardial injury by regulating miR-335 and RASA1 expression

Yanfeng Liu, Ping Zhou, Fengxiao Wang, Xuehong Zhang, Dongmei Yang, Lang Hong, Dongyun Ruan

Article Number: 597 Published online on: 22 June 2021
Article Open Access

Identification of differentially expressed proteins involved in fetal scarless wound healing using a rat model of cleft lip

Yu Yan, Hong Liu, Jiarong Yi, Zizi Chen, Jia Chen, Jianfei Zhang, Kewa Gao, Siqi He, Aijun Wang, Ping Jin, Feng Hu, Jianda Zhou

Article Number: 596 Published online on: 22 June 2021
Article Open Access

Targeted silencing of TEM8 suppresses non‑small cell lung cancer tumor growth via the ERK/Bcl‑2 signaling pathway

Quan Gong, Jing Deng, Lijuan Zhang, Chunyan Zhou, Chaojiang Fu, Xicai Wang, Li Zhuang

Article Number: 595 Published online on: 22 June 2021
Article Open Access

Excessive mechanical stretch‑mediated osteoblasts promote the catabolism and apoptosis of chondrocytes via the Wnt/β‑catenin signaling pathway

Cheng-Xian Song, Sheng-Yao Liu, Wen-Ting Zhu, Shao-Yong Xu, Guo-Xin Ni

Article Number: 593 Published online on: 17 June 2021
Article Open Access

Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He

Article Number: 592 Published online on: 17 June 2021
Article

Downregulation of VDR in benign paroxysmal positional vertigo patients inhibits otolith‑associated protein expression levels

Shu Zhang, Juanli Xing, Yulin Gong, Ping Li, Boqian Wang, Ling Xu

Article Number: 591 Published online on: 17 June 2021
Article Open Access

Dendrobium mixture attenuates renal damage in rats with diabetic nephropathy by inhibiting the PI3K/Akt/mTOR pathway

Yong Chen, Yan Fang Zheng, Xiao Hui Lin, Jie Ping Zhang, Fan Lin, Hong Shi

Article Number: 590 Published online on: 17 June 2021
Article Open Access

DNAJC2 is reversely regulated by miR‑627‑3p, promoting the proliferation of colorectal cancer

Hongfu Liu, Juan Li, Huali Zhao, Xiaohui Liu, Xinying Ye

Article Number: 589 Published online on: 16 June 2021
Article Open Access

miR‑205‑3p promotes lung cancer progression by targeting APBB2

Ling-Bin Xu, Jie Xiong, Ya-Hui Zhang, Yun Dai, Xiao-Ping Ren, Ya-Juan Ren, Dong Han, Sheng-Hong Wei, Min Qi

Article Number: 588 Published online on: 16 June 2021
Retraction Open Access

[Retracted] Additive effects of eukaryotic co‑expression plasmid carrying GRIM‑19 and LKB1 genes on breast cancer in vitro and in vivo

Wei Zhang, Ying Shao, Ye Du, Wei Geng, Tong Jiang, Haipeng Liu, Duo Zhang

Article Number: 587 Published online on: 16 June 2021
Retraction Open Access

[Retracted] Upregulation of GRIM‑19 inhibits the growth and invasion of human breast cancer cells

Wei Zhang, Ye Du, Tong Jiang, Wei Geng, Jiuli Yuan, Duo Zhang

Article Number: 586 Published online on: 16 June 2021
Article Open Access

Serum long non‑coding RNA NNT‑AS1 protected by exosome is a potential biomarker and functions as an oncogene via the miR‑496/RAP2C axis in colorectal cancer

Hua Yin, Jingjing Hu, Zhiying Ye, Saijun Chen, Yunwen Chen

Article Number: 585 Published online on: 15 June 2021
Article

SARS‑CoV‑2 spike protein‑induced host inflammatory response signature in human corneal epithelial cells

Guoqiang Zhu, Leyu Lyu, Hua Yang, Guibo Liu, Shuo Yang, Chuankai  Gu, Limei Wang, Haijing Yan, Ming Hu, Chengye Che

Article Number: 584 Published online on: 15 June 2021
Article Open Access

Regulation of angiogenesis by microRNAs in cancer

Qi Zheng, Wei Hou

Article Number: 583 Published online on: 15 June 2021
Article Open Access

MicroRNA‑193a‑5p exerts a tumor suppressive role in epithelial ovarian cancer by modulating RBBP6

Shuangli Zhang, Jun Liu, Jie He, Nuo Yi

Article Number: 582 Published online on: 15 June 2021
Article Open Access

Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway

Haixia Li, Xiaoyun Shen, Yifan Tong, Tong Ji, Yan Feng, Yanping Tang, Rongyun Mai, Jiaxiang Ye, Ting Que, Xiaoling Luo

Article Number: 580 Published online on: 14 June 2021
Retraction Open Access

[Retracted] miR‑200b inhibits migration and invasion in non‑small cell lung cancer cells via targeting FSCN1

Peng Xiao, Wenliang Liu, Hui Zhou

Article Number: 579 Published online on: 14 June 2021
Article Open Access

COVID‑19 vaccination and IgG and IgA antibody dynamics in healthcare workers

Sabina Zurac, Luciana Nichita, Bogdan Mateescu, Cristian Mogodici, Alexandra Bastian, Cristiana Popp, Mirela Cioplea, Claudiu Socoliuc, Carolina Constantin, Monica Neagu

Article Number: 578 Published online on: 13 June 2021
Article Open Access

High fluid shear stress prevents atherosclerotic plaque formation by promoting endothelium denudation and synthetic phenotype of vascular smooth muscle cells

Juan Wang, Yan Wang, Lin Sheng, Tian He, Xiang Nin, Aiying Xue, Hua Zhang, Zhendong Liu

Article Number: 577 Published online on: 13 June 2021
Article Open Access

MicroRNA‑16‑5p/BIMP1/NF‑κB axis regulates autophagy to exert a tumor‑suppressive effect on bladder cancer

Jiani He, Zhongkai Qiu, Hao Zhang, Zhipeng Gao, Yuanjun Jiang, Zhenhua Li, Chuize Kong, Xiaojun Man

Article Number: 576 Published online on: 13 June 2021
Article Open Access

Green tea protects against hippocampal neuronal apoptosis in diabetic encephalopathy by inhibiting JNK/MLCK signaling

Yongjie Xu, Shengju Liu, Liying Zhu, Longguang Dai, Wen Qian, Jingzhi Zhang, Xing Li, Wei Pan

Article Number: 575 Published online on: 10 June 2021
Article Open Access

Dexmedetomidine attenuates neuronal injury induced by cerebral ischemia‑reperfusion by regulating miR‑199a

Yulin Zhu, Huatang Zhao, Wenshan Zhang, Xingang Ma, Ye Liu

Article Number: 574 Published online on: 09 June 2021
Retraction Open Access

[Retracted] MicroRNA-200c inhibits the metastasis of non-small cell lung cancer cells by targeting ZEB2, an epithelial-mesenchymal transition regulator

Aihong Jiao, Minghua Sui, Liangming Zhang, Ping Sun, Dongmei Geng, Weiwei Zhang, Xiuwen Wang, Junxia Li

Article Number: 573 Published online on: 08 June 2021
Article Open Access

A report of two cases of bulbospinal form Alexander disease and preliminary exploration of the disease

Xiaoxuan Song, Jingwen Jiang, Wotu Tian, Feixia Zhan, Zeyu Zhu, Binyin Li, Huidong Tang, Li Cao

Article Number: 572 Published online on: 08 June 2021
Article Open Access

Baicalin relieves Mycoplasma pneumoniae infection‑induced lung injury through regulating microRNA‑221 to inhibit the TLR4/NF‑κB signaling pathway

Han Zhang, Xiang Li, Juan Wang, Qi Cheng, Yunxiao Shang, Guizhen Wang

Article Number: 571 Published online on: 08 June 2021
Retraction Open Access

[Retracted] MicroRNA‑138 inhibits migration and invasion of non‑small cell lung cancer cells by targeting LIMK1

Yanjuan Tan, Huaidong Hu, Wuyuan Tan, Longyu Jin, Jianxin Liu, Hui Zhou

Article Number: 570 Published online on: 08 June 2021
Retraction Open Access

[Retracted] MicroRNA‑10b suppresses the migration and invasion of chondrosarcoma cells by targeting brain‑derived neurotrophic factor

Abudunaibi Aili, Yong Chen, Hongqi Zhang

Article Number: 569 Published online on: 08 June 2021
Article Open Access

MicroRNA‑142‑3p suppresses cell proliferation, invasion and epithelial‑to‑mesenchymal transition via RAC1‑ERK1/2 signaling in colorectal cancer

Na Xie, Qiuping Meng, Yixin Zhang, Zhifei Luo, Fenggui  Xue, Sisi Liu, Ying Li, Yousheng Huang

Article Number: 568 Published online on: 07 June 2021
Article

miR‑483 promotes the development of colorectal cancer by inhibiting the expression level of EI24

Wei Zhou, Wanli Yang, Jing Yang, Haijun Zhu, Lili Duan, Xiaoqian Wang, Yiding Li, Liaoran Niu, Shuao Xiao, Rui Zhang, Jianjun Yang, Liu Hong

Article Number: 567 Published online on: 07 June 2021
Article Open Access

Long non‑coding RNA XIST promotes cerebral ischemia/reperfusion injury by modulating miR‑27a‑3p/FOXO3 signaling

Hua Zhang, Junyong Xia, Qiushan Hu, Liqin Xu, Hongyan Cao, Xu Wang, Min Cao

Article Number: 566 Published online on: 07 June 2021
Article Open Access

Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine‑resistant myeloid leukemia cells

Yu-Hsin Tseng, Rei-Cheng Yang, Shyh-Shin Chiou, Tzong-Ming Shieh, Yin-Hwa Shih, Pei-Chin Lin

Article Number: 565 Published online on: 07 June 2021
Article Open Access

Resveratrol affects the expression of uric acid transporter by improving inflammation

Xuemei Zhang, Qian Nie, Zhimei Zhang, Jing Zhao, Fengxiao Zhang, Chao Wang, Xing Wang, Guangyao Song

Article Number: 564 Published online on: 07 June 2021
Article Open Access

Effects of miR‑210‑3p on the erythroid differentiation of K562 cells under hypoxia

Caiyan Hu, Yupeng Yan, Chengbing Fu, Jin Ding, Tiantian Li, Shuqiong Wang, Liu Fang

Article Number: 563 Published online on: 07 June 2021
Article Open Access

miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1

Jin Wang, Ruixin Yao, Qiulin Luo, Lirong Tan, Beibei Jia, Nan Ouyang, Yezhou Li, Jian Tong, Jianxiang Li

Article Number: 562 Published online on: 06 June 2021
Article Open Access

Next‑generation sequencing of miRNAs and lncRNAs from rat femur and tibia under mechanical stress

Yiyan Qiu, Guozheng Zhu, Canjun Zeng, Song Yuan, Yuepeng Qian, Zelin Ye, Shanwen Zhao, Runguang Li

Article Number: 561 Published online on: 04 June 2021
Article Open Access

Shikonin inhibits the Warburg effect, cell proliferation, invasion and migration by downregulating PFKFB2 expression in lung cancer

Liying Sha, Zhiqiang Lv, Yujun Liu, Yun Zhang, Xin Sui, Teng Wang, Hui Zhang

Article Number: 560 Published online on: 04 June 2021
Article Open Access

Soluble fibrinogen‑like protein 2 levels are decreased in patients with ischemic heart failure and associated with cardiac function

Ya You, Shiyuan Huang, Hui Liu, Cheng Fan, Kun Liu, Zhaohui Wang

Article Number: 559 Published online on: 03 June 2021
Article Open Access

DHA ameliorates MeHg‑induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway

Hong Zhang, Susu Wang, Yaqian Wang, Anxin Lu, Chunping Hu, Chonghuai Yan

Article Number: 558 Published online on: 03 June 2021
Article Open Access

miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B

Chunrong Wu, Xiaohu Liu, Bo Li, Guiying Sun, Chunfang Peng, Debing Xiang

Article Number: 557 Published online on: 03 June 2021
Article Open Access

An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level

Miguel A. Ortega, Ángel Asúnsolo, Oscar Fraile‑Martínez, Felipe Sainz, Miguel A. Saez, Coral Bravo, Juan A. De León‑Luis, Miguel A. Alvarez‑Mon, Santiago Coca, Melchor Álvarez‑Mon, Julia Buján, Natalio García‑Honduvilla

Article Number: 556 Published online on: 02 June 2021
Article Open Access

Ginkgolide J protects human synovial cells SW982 via suppression of p38‑dependent production of pro‑inflammatory mediators

Yujie Zhao, Yuan Chen, Jiayi Wang, Xue Zhu, Ke Wang, Yue Li, Fanfan Zhou

Article Number: 555 Published online on: 02 June 2021
Article Open Access

Mechanism underlying long non‑coding RNA ILF3‑AS1‑mediated inhibition of cervical cancer cell proliferation, invasion and migration, and promotion of apoptosis

Linmei Zhu, Ruixia Chen, Chunlin Jiang, Qingsheng Xie, Wenshuai Zhao, Xiaohong Gao, Haiming Huang

Article Number: 554 Published online on: 02 June 2021
Article

lncRNA TUG1 regulates angiogenesis via the miR‑204‑5p/JAK2/STAT3 axis in hepatoblastoma

Miao-Xian Yuan, Chun-Yi Ji, Hong-Qiang Gao, Xin-Yi Sheng, Wei-Xin Xie, Qiang Yin

Article Number: 553 Published online on: 02 June 2021
Article Open Access

Long non‑coding RNA HCG11 suppresses the malignant phenotype of non‑small cell lung cancer cells by targeting a miR‑875/SATB2 axis

Zhou Su, Mi Chen, Ruilin Ding, Lian Shui, Qingmei Zhao, Wenjuan Luo

Article Number: 552 Published online on: 02 June 2021
Article Open Access

SMARCC2 combined with c‑Myc inhibits the migration and invasion of glioma cells via modulation of the Wnt/β‑catenin signaling pathway

Chiyang Li, Chengshuo Fei, Junjie Li, Hang Wu, Lei Chen, Ramzi Roshani, Hong Li, Linyong Shi, Chong Song, Junwei Gu, Yuntao Lu, Qiang Zhou

Article Number: 551 Published online on: 02 June 2021
Article Open Access

Porcupine inhibitor LGK‑974 inhibits Wnt/β‑catenin signaling and modifies tumor‑associated macrophages resulting in inhibition of the malignant behaviors of non‑small cell lung cancer cells

Yang Tang, Maoyan Jiang, Anping Chen, Wendong Qu, Xu Han, Jiebin Zuo, Gang Xu, Yongxiang Song, Cheng Chen, Xixian Ke

Article Number: 550 Published online on: 02 June 2021
Article Open Access

HIGD‑1B inhibits hypoxia‑induced mitochondrial fragmentation by regulating OPA1 cleavage in cardiomyocytes

Yan Pang, Zhide Zhu, Zhihao Wen, Junshen Lu, Hao Lin, Meiling Tang, Zhiliang Xu, Jianqi Lu

Article Number: 549 Published online on: 02 June 2021
Article Open Access

MAPK4 silencing together with a PARP1 inhibitor as a combination therapy in triple‑negative breast cancer cells

Xiaoqi Zeng, Shanshan Jiang, Simin Ruan, Zhaoze Guo, Jingyun Guo, Minfeng Liu, Changsheng Ye, Jianyu Dong

Article Number: 548 Published online on: 02 June 2021
Article Open Access

Critical role of SIRT1 upregulation on the protective effect of lncRNA ANRIL against hypoxia/reoxygenation injury in H9c2 cardiomyocytes

Binghui Song, Dongmei Wei, Gang Yin, Xiaoguang Song, Shuqing Wang, Shanshan Jia, Jidong Zhang, Longhu Li, Xiaofei Wu

Article Number: 547 Published online on: 02 June 2021
Retraction Open Access

[Retracted] Knockdown of PREX2a inhibits the malignant phenotype of glioma cells

Liang Liu, Zhixiong Liu, Hao Wang, Long Chen, Fuqiang Ruan, Jihui Zhang, Yi Hu, Hengshan Luo, Shuai Wen

Article Number: 545 Published online on: 01 June 2021
Article Open Access

Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage‑induced brain injury via necroptosis and neuroinflammation

Lixiang Yang, Yue Wang, Can Zhang, Huilin Cheng

Article Number: 544 Published online on: 29 May 2021
Article Open Access

Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell

Lu Chang, Rui Zhou, Yihan He, Mei Meng, Jinhang Hu, Yanru Liu, Yalei Pan, Zhishu Tang, Zhenggang Yue

Article Number: 542 Published online on: 29 May 2021
Journal Cover

August-2021
Volume 24 Issue 2

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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