Journal Articles

Review Open Access

Dual effects of active ERK in cancer: A potential target for enhancing radiosensitivity (Review)

Yinliang Lu, Baocai Liu, Ying Liu, Xinyue Yu, Guanghui Cheng

Pages: 993-1000 Published online on: 28 May 2020
Review

Anlotinib as a molecular targeted therapy for tumors (Review)

Yi Gao, Pengfei Liu, Ruihua Shi

Pages: 1001-1014 Published online on: 28 May 2020
Review Open Access

Telomeres and telomerase in oncogenesis (Review)

Tomasz Trybek, Artur Kowalik, Stanisław Góźdź, Aldona Kowalska

Pages: 1015-1027 Published online on: 21 May 2020
Article Open Access

Diagnostic value of Doppler ultrasound parameters combined with MMP-11 in early breast cancer and benign breast diseases

Hui Ren, Zhipeng Shen, Jirui Shen, Yu Zhang, Yunhua Zhang

Pages: 1028-1032 Published online on: 28 May 2020
Article Open Access

Expression of anti‑apoptotic protein survivin in human endometrial carcinoma: Clinical and pathological associations as a separate factor and in combination with concomitant PTEN and p53 expression

Aggelis Stavropoulos, Michail Varras, Thivi Vasilakaki, Viktoria‑Konstantina Varra, Fani‑Niki Varra, Aikaterini Tsavari, Aphrodite Nonni, Nikolaos Kavantzas, Andreas C. Lazaris

Pages: 1033-1054 Published online on: 30 May 2020
Article Open Access

Rab5 regulates the proliferation, migration and invasion of glioma cells via cyclin E

Zhao Jian, Lianglong Zhang, Liang Jin, Weitu Lan, Wei Zhang, Guiyan Gao

Pages: 1055-1062 Published online on: 21 May 2020
Article Open Access

GGCT promotes colorectal cancer migration and invasion via epithelial‑mesenchymal transition

Qi Huang, Yuanhang Zhou, Yue Li, Zhiwei Liao

Pages: 1063-1070 Published online on: 30 May 2020
Article Open Access

Mutations in the BCR‑ABL1 kinase domain in patients with chronic myeloid leukaemia treated with TKIs or at diagnosis

Jingjing Liu, Haiping Yang, Xiuwen Xu, Shujuan Yi, Li Meng

Pages: 1071-1076 Published online on: 20 May 2020
Article Open Access

Effect of dexmedetomidine on brain function and hemodynamics in patients undergoing lung cancer resection

Yunfeng Li, Chunyu Wang, Mingzhuang Bi, Jie Gao, Xue Zhang, Haitao Tian

Pages: 1077-1082 Published online on: 28 May 2020
Article Open Access

Elevated CELSR3 expression is associated with hepatocarcinogenesis and poor prognosis

Xiwu Ouyang, Zhiming Wang, Lei Yao, Gewen Zhang

Pages: 1083-1092 Published online on: 22 May 2020
Article Open Access

RNAi-mediated IARS2 knockdown inhibits proliferation and promotes apoptosis in human melanoma A375 cells

Dongmei Ma, Song Li, Xiaojuan Nie, Lamei Chen, Nan Chen, Dongsheng Hou, Xiuhong Liu, Binbin Gao

Pages: 1093-1100 Published online on: 29 May 2020
Article Open Access

Blood cell parameters as prognostic predictors of disease development for patients with advanced non‑small cell lung cancer

Leirong Wang, Hongzong Si, Jing Wang, Lingxin Feng, Wenxin Zhai, Shenghua Dong, Zhuang Yu

Pages: 1101-1110 Published online on: 21 May 2020
Article Open Access

Clinical significance of ring finger protein 2 high expression in skin squamous cell carcinoma

Bai Ling, Ming Yao, Gongqi Li, Jun Liu, Bin Liu, Wei Wang, Bin Jiang

Pages: 1111-1118 Published online on: 22 May 2020
Article Open Access

Serum microRNA‑592 serves as a novel potential biomarker for early diagnosis of colorectal cancer

Zhenguo Pan, Lin Miao

Pages: 1119-1126 Published online on: 28 May 2020
Article Open Access

PD‑L1 expression increased by IFN‑γ via JAK2‑STAT1 signaling and predicts a poor survival in colorectal cancer

Tiancheng Zhao, Yezhou Li, Jiayu Zhang, Bin Zhang

Pages: 1127-1134 Published online on: 20 May 2020
Article Open Access

Effective pressure and treatment duration of high hydrostatic pressure to prepare melanoma vaccines

Kai Liu, Shuai Yan, Zhanchuan Ma, Bin Liu

Pages: 1135-1142 Published online on: 21 May 2020
Article Open Access

MICA enhances sensitivity to cisplatin in patients with extensive small cell lung cancer via downregulation of ABCG2

Yufeng Wu, Hong Tang, Ruirui Si, Suhua Xia, Ruilin Wang, Qiming Wang

Pages: 1143-1152 Published online on: 19 May 2020
Article Open Access

Dihydropyrimidinase‑related protein 5 controls glioblastoma stem cell characteristics as a biomarker of proneural‑subtype glioblastoma stem cells

Min Gi Park, Sunyoung Seo, Seok Won Ham, Sang‑Hun Choi, Hyunggee Kim

Pages: 1153-1162 Published online on: 22 May 2020
Article Open Access

Downregulation of VRK1 reduces the expression of BANF1 and suppresses the proliferative and migratory activity of esophageal cancer cells

Zhenzhen Ren, Jie Geng, Chao Xiong, Xuebing Li, Yuqing Li, Jin Li, Hongchun Liu

Pages: 1163-1170 Published online on: 21 May 2020
Article Open Access

Enhancement of O‑linked N‑acetylglucosamine modification promotes metastasis in patients with colorectal cancer and concurrent type 2 diabetes mellitus

Yutaka Naka, Toshihiko Okada, Takatoshi Nakagawa, Eiko Kobayashi, Yuka Kawasaki, Yasuyoshi Tanaka, Hideki Tawa, Yuki Hirata, Ken Kawakami, Kazuki Kakimoto, Takuya Inoue, Toshihisa Takeuchi, Shinya Fukunishi, Yoshinobu Hirose, Kazuhisa Uchiyama, Michio Asahi, Kazuhide Higuchi

Pages: 1171-1178 Published online on: 22 May 2020
Article Open Access

IQGAP3 promotes cancer proliferation and metastasis in high‑grade serous ovarian cancer

Samina Dongol, Qing Zhang, Chunping Qiu, Chenggong Sun, Zhiwei Zhang, Huan Wu, Beihua Kong

Pages: 1179-1192 Published online on: 21 May 2020
Article Open Access

Multitarget stool DNA test compared with fecal occult blood test for colorectal cancer screening

Cuiping Yang, Wei Wu, Yanping Yang, Xiaojin Yang, Jing Sun, Weiyu Zhang, Kun Liu, Haifeng Ying, Songyao Jiang, Xiaojun Yu, Yiqing Shi, Yufen Zhou, Shiyan Zhu, Ying Xu, Yanfei Ding, Ling Xie, Boer  Cai, Xiaorong Xin, Ping Chen, Ren Zhao, Yunlin Wu

Pages: 1193-1200 Published online on: 25 May 2020
Article Open Access

Integrated analysis revealing genome‑wide chromosomal copy number variation in supraglottic laryngeal squamous cell carcinoma

Dongjie Li, Xianfu Wang, Shunfei Lu, Ping Wang, Xin Wang, Wanzhong Yin, Wei Zhu, Shibo Li

Pages: 1201-1212 Published online on: 21 May 2020
Article Open Access

Overexpression of miR‑518b in non‑small cell lung cancer serves as a biomarker and facilitates tumor cell proliferation, migration and invasion

Xinfang Zhang, Ying Hu, Cuixue Gong, Chunjie Zhang

Pages: 1213-1220 Published online on: 22 May 2020
Article Open Access

CD73 promotes colitis‑associated tumorigenesis in mice

Xuan‑Hui Liu, Xian‑Rui Wu, Nan Lan, Xiao‑Bin Zheng, Chi Zhou, Tuo Hu, Yu‑Feng Chen, Ze‑Rong Cai, Ze‑Xian Chen, Ping Lan, Xiao‑Jian Wu

Pages: 1221-1230 Published online on: 22 May 2020
Article Open Access

Increased frequency of ESR1 mutation in metastatic breast cancer by dosing selective estrogen receptor modulator followed by aromatase inhibitor

Kaoru Takeshima, Tetsu Hayashida, Hinako Maeda, Ayako Nakashoji, Takamichi Yokoe, Tomoko Seki, Maiko Takahashi, Yuko Kitagawa

Pages: 1231-1238 Published online on: 22 May 2020
Article Open Access

Fisetin inhibits vascular endothelial growth factor‑induced angiogenesis in retinoblastoma cells

Liangjun Wang, Ning Chen, Hongxia Cheng

Pages: 1239-1244 Published online on: 28 May 2020
Article Open Access

Predicting tumor recurrence using metabolic indices of 18F‑FDG PET/CT prior to orthotopic liver transplantationfor hepatocellular carcinoma

Enci Ding, Dongyan Lu, Lijuan Wei, Xuemin Feng, Jie Shen, Wengui Xu

Pages: 1245-1255 Published online on: 28 May 2020
Article Open Access

Function of miR-200a in proliferation and apoptosis of non-small cell lung cancer cells

Yan Huang, Ting Bao, Zhenzhen Li, Guiyi Ji, Li Zhang

Pages: 1256-1262 Published online on: 20 May 2020
Article Open Access

Effect of bevacizumab on expression level of GLI1 and ING4 in colon cancer animal model

Bing Suo, Caiyu Wu, Fen Mei

Pages: 1263-1269 Published online on: 28 May 2020
Article Open Access

Long non‑coding RNA RFPL3S is a novel prognostic biomarker in lung cancer

Zhonghua Liu, Zhiqiang Ning, Hailin Lu, Tinghua Cao, Feng Zhou, Xia Ye, Chao Chen

Pages: 1270-1280 Published online on: 19 May 2020
Article Open Access

Tumor suppressor role of miR‑876‑5p in gastric cancer

Hongwei Zhao, Yuzhu Zheng, Jia You, Jingyuan Xiong, Shi Ying, Linshen Xie, Xuejiao Song, Yuqin Yao, Zhaohui Jin, Chaoxiong Zhang

Pages: 1281-1287 Published online on: 28 May 2020
Article Open Access

Effect of bortezomib on proliferation and apoptosis of myeloma cells by activating Wnt/β‑catenin signaling pathway

Yanling Dai, Xiaomin Guo, Chunyan Yang

Pages: 1295-1299 Published online on: 28 May 2020
Article Open Access

Mining the prognostic significance of the GINS2 gene in human breast cancer using bioinformatics analysis

Shibo Yu, Lizhe Zhu, Peiling Xie, Siyuan Jiang, Ke Wang, Yang Liu, Jianjun He, Yu Ren

Pages: 1300-1310 Published online on: 20 May 2020
Article Open Access

Expression of Krüppel-like factor 9 in breast cancer patients and its effect on prognosis

Zirong Jiang, Zhiping Xu, Tinghui Hu, Bin Song, Feng Li, Kaiyin Wang

Pages: 1311-1317 Published online on: 29 May 2020
Article Open Access

AGXT2L1 is downregulated in carcinomas of the digestive system

Yunchao Deng, Lu Wu, Qianshan Ding, Honggang Yu

Pages: 1318-1326 Published online on: 19 May 2020
Article Open Access

Identification of key genes for guiding chemotherapeutic management in ovarian cancer using translational bioinformatics

Danni Yuan, Haohan Zhou, Hongyu Sun, Rui Tian, Meihui Xia, Liankun Sun, Yanan Liu

Pages: 1345-1359 Published online on: 22 May 2020
Article Open Access

ALOX12B promotes carcinogenesis in cervical cancer by regulating the PI3K/ERK1 signaling pathway

Tao Jiang, Bing Zhou, Yuan Meng Li, Qui Ying Yang, Kai Jia Tu, Long Yu Li

Pages: 1360-1368 Published online on: 19 May 2020
Article Open Access

Long non‑coding RNA LINC00460 predicts poor survival and promotes cell viability in pancreatic cancer

Junfeng Sun, Jianying Yang, Kui Lv, Jianguo Guan

Pages: 1369-1375 Published online on: 20 May 2020
Article Open Access

Thyroid transcription factor 1 and p63 expression is associated with survival outcome in patients with non‑small cell lung cancer treated with erlotinib

Martin Svaton, Ondrej Fiala, Gabriela Krakorova, Jiri Blazek, Karolina Hurdalkova, Magda Barinova, Petr Mukensnabl, Milos Pesek

Pages: 1376-1382 Published online on: 21 May 2020
Article Open Access

Pan‑cancer analysis reveals the role of long non‑coding RNA LINC01614 as a highly cancer‑dependent oncogene and biomarker

Dingding Wang, Hong Zhang, Xiaolian Fang, Dingfang Cao, Honggang Liu

Pages: 1383-1399 Published online on: 20 May 2020
Article Open Access

Enoxacin inhibits proliferation and invasion of human osteosarcoma cells and reduces bone tumour volume in a murine xenograft model

Xuwen Luo, Xuqiang Liu, Qianyuan Tao, Cong Yao, Fuqiang Wang, Zhiping Gu, Feilong Li, Xiaolong Yu, Bin Zhang, Hongxian Fan, Min Dai, Tao Nie

Pages: 1400-1408 Published online on: 21 May 2020
Article Open Access

Fat mass and obesity-associated protein promotes the tumorigenesis and development of liver cancer

Ziqi Ye, Shibing Wang, Wanyuan Chen, Xin Zhang, Jie Chen, Jinying Jiang, Mingshan Wang, Li Zhang, Zixue Xuan

Pages: 1409-1417 Published online on: 25 May 2020
Article Open Access

The auxiliary diagnostic value of prostate‑specific antigen and α‑methylacyl‑CoA racemase in prostate cancer

Daijun Yang, Xiang Shi, Yu Lei, Xianrong Zhou, Qiuxiang Chen

Pages: 1418-1422 Published online on: 21 May 2020
Article Open Access

IGF2BP3 and miR191‑5p synergistically increase HCC cell invasiveness by altering ZO‑1 expression

Yuan Gao, Tianping Luo, Xiwu Ouyang, Chunfu Zhu, Junqiang Zhu, Xihu Qin

Pages: 1423-1431 Published online on: 30 May 2020
Article Open Access

Circulating exosomal microRNAs as novel potential detection biomarkers in pancreatic cancer

Lun Wu, Wen‑Bo Zhou, Jiao Zhou, Ying Wei, Hong‑Mei Wang, Xian‑De Liu, Xiao‑Chun Chen, Wei Wang, Lin Ye, Li Chao Yao, Qin‑Hua Chen, Zhi‑Gang Tang

Pages: 1432-1440 Published online on: 30 May 2020
Article Open Access

AGR3 promotes estrogen receptor‑positive breast cancer cell proliferation in an estrogen‑dependent manner

Lei Jian, Jian Xie, Shipeng Guo, Haochen Yu, Rui Chen, Kai  Tao, Chengcheng Yang, Kang Li, Shengchun Liu

Pages: 1441-1451 Published online on: 28 May 2020
Article

Identification of long non‑coding RNA SCARNA9L as a novel molecular target for colorectal cancer

Jie Chai, Jianbo Zhang, Dali Han, Wei Dong, Li Han, Lei Zou, Bin Feng, Baosheng Li, Wanli Ma

Pages: 1452-1461 Published online on: 21 May 2020
Article

Role of ubiquitin‑conjugating enzyme E2T in the carcinogenesis and progression of pancreatic cancer

Yuan‑Wen Zheng, Peng‑Fei Gao, Ming‑Ze Ma, Yong Chen, Chun‑You Li

Pages: 1462-1468 Published online on: 19 May 2020
Article

Inflammatory cytokines, appetite‑regulating hormones, and energy metabolism in patients with gastrointestinal cancer

Ayaka Shinsyu, Shigeki Bamba, Mika Kurihara, Hiroshi Matsumoto, Ayano Sonoda, Osamu Inatomi, Akira Andoh, Katsushi Takebayashi, Masatsugu Kojima, Hiroya Iida, Masaji Tani, Masaya Sasaki

Pages: 1469-1479 Published online on: 21 May 2020
Review Open Access

Ailanthone: A novel potential drug for treating human cancer (Review)

Haixiang Ding, Xiuchong Yu, Chen Hang, Kaijun Gao, Xifeng Lao, Yangtao Jia, Zhilong Yan

Pages: 1489-1503 Published online on: 09 June 2020
Review

N6‑methyladenine RNA modification and cancer (Review)

Jun Yang, Junwen Chen, Xiang Fei, Xia Wang, Kefeng Wang

Pages: 1504-1512 Published online on: 16 June 2020
Review Open Access

Ambiguous roles and potential therapeutic strategies of innate lymphoid cells in different types of tumor (Review)

Shijie Wang, Pin Wu, Yongyuan Chen, Ying Chai

Pages: 1513-1525 Published online on: 16 June 2020
Article Open Access

Function and regulation of F‑box/WD repeat‑containing protein 7 (Review)

Zheng Zhang, Qiangsheng Hu, Wenyan Xu, Wensheng  Liu, Mengqi Liu, Qiqing  Sun, Zeng Ye, Guixiong Fan, Yi  Qin, Xiaowu Xu, Xianjun Yu, Shunrong Ji

Pages: 1526-1534 Published online on: 11 June 2020
Article Open Access

Overexpression of B7‑H4 promotes renal cell carcinoma progression by recruiting tumor‑associated neutrophils via upregulation of CXCL8

Anqi Li, Ningyue Zhang, Zhiming Zhao, Yali Chen, Liang Zhang

Pages: 1535-1544 Published online on: 05 June 2020
Article Open Access

Clinicopathological characteristics, adjuvant chemotherapy decision and disease outcome in patients with breast cancer with a 21‑gene recurrence score of 26‑30

Jing Yu, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Weiguo  Chen, Yafen Li, Xiaosong Chen, Kunwei Shen

Pages: 1545-1556 Published online on: 16 June 2020
Article Open Access

RNAseq profiling of circRNA expression in radiation‑treated A549 cells and bioinformatics analysis of radiation‑related circRNA‑miRNA networks

Ting Zhang, Dong‑Ming Wu, Shi‑Hua Deng, Rong Han, Teng Liu, Jing Li, Ying Xu

Pages: 1557-1566 Published online on: 05 June 2020
Case Report Open Access

Tumor with slow‑developing and recurring lumps of the external ear with skull base and lung metastasis: A case report

Zhifang Zhai, Jie Hu, Yi You, Xichuan Yang, Zhiqiang Song

Pages: 1567-1572 Published online on: 11 June 2020
Article Open Access

Integrated bioinformatics analysis for the identification of potential key genes affecting the pathogenesis of clear cell renal cell carcinoma

Hao Cui, Lei Xu, Zhi Li, Ke‑Zuo Hou, Xiao‑Fang Che, Bo‑Fang Liu, Yun‑Peng Liu, Xiu‑Juan Qu

Pages: 1573-1584 Published online on: 05 June 2020
Article Open Access

Identifying key genes and drug screening for preeclampsia based on gene expression profiles

Zhengfang Xu, Chengjiang Wu, Yanqiu Liu, Nian Wang, Shujun Gao, Shali Qiu, Zhutao Wang, Jing Ding, Lubin Zhang, Hui Wang, Weijiang Wu, Bing Wan, Jun Yu, Jie Fang, Peifang Yang, Qixiang Shao

Pages: 1585-1596 Published online on: 09 June 2020
Article Open Access

Serum profile of low molecular weight fucosylated glycoproteins for early diagnosis of hepatocellular carcinoma

Weirong Yao, Kaiyu Wang, Yu Jiang, Zhufeng Huang, Yiyun Huang, Huihui Yan, Suhong Huang, Min Chen, Jian Liao

Pages: 1597-1606 Published online on: 11 June 2020
Article Open Access

Conditional survival rate estimates of lobectomy, segmentectomy and wedge resection for stage IA1 non‑small cell lung cancer: A population‑based study

Xiaoxi Fan, Yicheng Liang, Yunpeng Bai, Chunlu Yang, Shun Xu

Pages: 1607-1618 Published online on: 09 June 2020
Article Open Access
Article Open Access

Increased DEF6 expression is correlated with metastasis and poor prognosis in human osteosarcoma

Qiao Zhang, Guo‑Sheng Zhao, Ya Cao, Xue‑Feng Tang, Qiu‑Lin Tan, Lu Lin, Qiao‑Nan Guo

Pages: 1629-1640 Published online on: 17 June 2020
Article Open Access

Clinical characteristics, treatment and prognosis of angiocentric glioma

Guoqing Han, Junsi Zhang, Yue Ma, Qiuping Gui, Shi Yin

Pages: 1641-1648 Published online on: 10 June 2020
Article Open Access

Association between the methylation status of PCDH17 and the efficacy of neoadjuvant chemotherapy in triple-negative breast cancer

De-Di Kong, Rong-Zhan Fu, Liang Li, Wei Wang, Shi-Bing Wang

Pages: 1649-1656 Published online on: 16 June 2020
Article Open Access

Comparison of PICC and TIVAP in chemotherapy for patients with thyroid cancer

Fangmei Qi, Hairong Cheng, Xiying Yuan, Li Zhang

Pages: 1657-1662 Published online on: 15 June 2020
Article Open Access

MicroRNA‑505‑3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression

Zhenlin Cheng, Bin Wang, Cheng Zhang

Pages: 1663-1670 Published online on: 09 June 2020
Article Open Access

Comparison of image features and diagnostic value of color Doppler ultrasound and two-dimensional ultrasound in the diagnosis of ovarian sex cord-stromal tumors

Guannan He, Jing Zhao, Zhirong Yang, Zhigang Zhao, Yan Bai, Wen Xiong

Pages: 1671-1676 Published online on: 05 June 2020
Article Open Access

Prognostic value of immune cell infiltration in bladder cancer: A gene expression‑based study

Yao Wang, Hong‑Jun Ba, Zi‑Chuan Liu, Xu‑Bin Deng, Min Zhou

Pages: 1677-1684 Published online on: 17 June 2020
Article Open Access

Expression, association with clinicopathological features and prognostic potential of CEP55, p‑Akt, FoxM1 and MMP‑2 in astrocytoma

Saisai Nie, Lei Lou, Juan Wang, Jinfeng Cui, Wenxin Wu, Qing Zhang, Ying Liu, Lingrui Su, Ying Chang, Wenli Guo, Haitao Shen, Lingxiao Xing, Yuehong Li

Pages: 1685-1694 Published online on: 17 June 2020
Article Open Access

Identification of hub genes involved in the occurrence and development of hepatocellular carcinoma via bioinformatics analysis

Ningning Mi, Jie Cao, Jinduo Zhang, Wenkang Fu, Chongfei Huang, Long Gao, Ping Yue, Bing Bai, Yanyan Lin, Wenbo Meng, Xun Li

Pages: 1695-1708 Published online on: 17 June 2020
Article Open Access

Levels of MUC1 in tumours and serum of patients with different sub‑types of squamous cell carcinoma of the head and neck

Linda Boldrup, Philip Coates, Xiaolian Gu, Lixiao Wang, Robin Fåhraeus, Torben Wilms, Nicola Sgaramella, Jonathan Baumgarth, Lena Norberg‑Spaak, Karin Nylander

Pages: 1709-1718 Published online on: 17 June 2020
Article Open Access

Mechanism of miR‑98 inhibiting tumor proliferation and invasion by targeting IGF1R in diabetic patients combined with colon cancer

Shixiong Liu, Yun Zhou, Yongning Zhou, Jing Wang, Rui Ji

Pages: 1719-1726 Published online on: 09 June 2020
Article Open Access

Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma

Tomoki Kohno, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Joji Tani, Kei Takuma, Mai Nakahara, Kyoko Oura, Tomoko Tadokoro, Takako Nomura, Hirohito Yoneyama, Kiyohito Kato, Keiichi Okano, Yasuyuki Suzuki, Akira Nishiyama, Takashi Himoto, Tsutomu Masaki

Pages: 1727-1733 Published online on: 05 June 2020
Article Open Access

Increased expression of EHMT2 associated with H3K9me2 level contributes to the poor prognosis of gastric cancer

Ping Chen, Qi Qian, Zhiyuan Zhu, Xiaohui Shen, Shenling Yu, Zhenghong Yu, Rui Sun, Yiping Li, Didi Guo, Hong Fan

Pages: 1734-1742 Published online on: 05 June 2020
Article Open Access

MKP‑1 overexpression is associated with chemoresistance in bladder cancer via the MAPK pathway

Siyu Lei, Hong Xu, Naiwen Chen, Huan Pan, Wenhua Xie, Yi He, Jing Jin

Pages: 1743-1751 Published online on: 16 June 2020
Article Open Access

Association between APOBEC3s and HPV16 E2 gene hypermutation in Uygur females with cervical cancer

Shuang Sui, Zhen Jiao, Hongxiang Chen, Mayinuer Niyazi, Lin Wang

Pages: 1752-1760 Published online on: 05 June 2020
Article Open Access

Caprin‑1 promotes HepG2 cell proliferation, invasion and migration and is associated with poor prognosis in patients with liver cancer

Xin‑Min Guo, Fang‑Fang Zhu, Li‑Wen Pan, Jia‑Lin Chen, Ji‑Chuang Lai, Hong‑Xia Wu, Jian‑Chang Shu

Pages: 1761-1771 Published online on: 09 June 2020
Article Open Access

Identification and validation of tumor microenvironment‑related genes of prognostic value in lung adenocarcinoma

Jingyan Yuan, Bo Yuan, Lizhong Zeng, Boxuan Liu, Yang Chen, Xia Meng, Ruiying Sun, Xin Lv, Wei Wang, Shuanying Yang

Pages: 1772-1780 Published online on: 16 June 2020
Article Open Access

Effects of the IL6 ‑174G>C promoter polymorphism and IL‑6 serum levels on the progression of cutaneous malignant melanoma

Tatyana Vlaykova, Mateuzh Kurzawski, Tanya Tacheva, Dimo Dimov, Asen Anastasov, Denitsa Vlaykova, Ani Miteva, Niamh O'Donoghue, Marek Drozdzik

Pages: 1781-1791 Published online on: 16 June 2020
Article Open Access

Protein expression profiles that underpin the preventive and therapeutic potential of Moringa oleifera Lam against azoxymethane and dextran sodium sulfate‑induced mouse colon carcinogenesis

Phatchariya Phannasil, Sittiruk Roytrakul, Narumon Phaonakrop, Piengchai Kupradinun, Sirintip Budda, Chaniphun Butryee, Chareeporn Akekawatchai, Siriporn Tuntipopipat

Pages: 1792-1802 Published online on: 11 June 2020
Article Open Access

Cloning of the XPD gene and its function in malignant melanoma cells

Yue Wang, Youyou Zhou, Yanfu Wang, Cong Peng, Mingyang Gao

Pages: 1803-1809 Published online on: 09 June 2020
Article Open Access

Analysis of factors affecting the prognosis of patients with cervical intraepithelial neoplasia 2

Xiaobo Zhang, Yougui Xu, Tianyu Meng, Danhua Shen

Pages: 1810-1816 Published online on: 09 June 2020
Article Open Access

SDF‑1/CXCR4 induces cell invasion through CD147 in squamous cell carcinoma of the hypopharynx

Satoshi Toyoma, Shinsuke Suzuki, Yohei Kawasaki, Takechiyo Yamada

Pages: 1817-1823 Published online on: 17 June 2020
Article Open Access

Genomic analysis of biomarkers related to the prognosis of acute myeloid leukemia

Guilan Li, Yang Gao, Kun Li, Anqi Lin, Zujun Jiang

Pages: 1824-1834 Published online on: 05 June 2020
Article Open Access

CSF1R methylation is a key regulatory mechanism of tumor‑associated macrophages in hepatocellular carcinoma

Bin Cui, Xiaoxiao Fan, Daizhan Zhou, Lifeng He, Yirun Li, Dandan Li, Hui Lin

Pages: 1835-1845 Published online on: 11 June 2020
Article Open Access

Long non‑coding RNA EWSAT1 contributes to the proliferation and invasion of glioma by sponging miR‑152‑3p

Hui Yang, Weida Chen, Guangyu Jiang, Jun Yang, Weifeng Wang, Hongbin Li

Pages: 1846-1854 Published online on: 09 June 2020
Article Open Access

Association between TP53 gene deletion and protein expression in esophageal squamous cell carcinoma and its prognostic significance

Madiniyet Niyaz, Julaiti Ainiwaer, Abulajiang Abudureheman, Liwei Zhang, Ilyar Sheyhidin, Abduheny Turhong, Ren Cai, Zhichao Hou, Edris Awut

Pages: 1855-1865 Published online on: 09 June 2020
Article Open Access

Wide‑ranging analysis of survival‑related alternative splicing events in invasive breast carcinoma

Keren Jia, Yingcheng Wu, Jing Huang, Jianing Chen, Huagen Wei, Huiqun Wu

Pages: 1866-1878 Published online on: 05 June 2020
Article Open Access

Extravasated platelet aggregation contributes to tumor progression via the accumulation of myeloid‑derived suppressor cells in gastric cancer with peritoneal metastasis

Takahisa Yamaguchi, Sachio Fushida, Jun Kinoshita, Mitsuyoshi Okazaki, Satoko Ishikawa, Yoshinao Ohbatake, Shiro Terai, Koichi Okamoto, Shinichi Nakanuma, Isamu Makino, Keishi Nakamura, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Tetsuo Ohta

Pages: 1879-1887 Published online on: 10 June 2020
Article Open Access

HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway

Xia‑Yin Zhu, Qun‑Yi Guo, Min Zhu, Bao‑Guo Chen, Ling‑Yan Wang, Dan‑Qiong Zhang, Li Zhang, Yan‑Ping Shao, Wen‑Da Luo

Pages: 1888-1896 Published online on: 09 June 2020
Article Open Access

Development and validation of a hypoxia‑related prognostic signature for breast cancer

Jianxin Wang, Yuquan Wang, Ping Xing, Qianqi Liu, Cong Zhang, Yang Sui, Changjun Wu

Pages: 1906-1914 Published online on: 16 June 2020
Article Open Access

Multiple sexual partners and vaginal microecological disorder are associated with HPV infection and cervical carcinoma development

Yu Huang, Xinzhi Wu, Ying Lin, Wenzhou Li, Jiahua Liu, Baozhi Song

Pages: 1915-1921 Published online on: 16 June 2020
Article Open Access

Efficacy of abiraterone combined with flutamide on prostate cancer patients and its effect on serum miR-493-5p and miR-195-5p

Chunyan Yang, Yanling Dai, Shuhua Pang, Xiaomin Guo

Pages: 1922-1930 Published online on: 09 June 2020
Article Open Access

MicroRNA‑147 targets BDNF to inhibit cell proliferation, migration and invasion in non‑small cell lung cancer

Fang Li, Xianfang Wang, Lingling Yang

Pages: 1931-1937 Published online on: 09 June 2020
Article Open Access

Clinical significance of miR‑372 and miR‑495 in acute myeloid leukemia

Wei Zhang, Bo Wan, Bei Liu, Shiwen Wu, Li Zhao

Pages: 1938-1944 Published online on: 17 June 2020
Article Open Access

Correlation of Fibulin‑2 expression with proliferation, migration and invasion of breast cancer cells

Xiliang Zhang, Lian Duan, Yuxing Zhang, Huibin Zhao, Xiaodong Yang, Chaojun Zhang

Pages: 1945-1951 Published online on: 17 June 2020
Article Open Access

miR‑494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway

Fen Xu, Guiqin Liu, Lijuan Wang, Xiyan Wang, Xiao Jin, Wen Bo

Pages: 1952-1960 Published online on: 17 June 2020
Article Open Access

Establishment of C20Mab‑11, a novel anti‑CD20 monoclonal antibody, for the detection of B cells

Yoshikazu Furusawa, Mika Kato Kaneko, Yukinari Kato

Pages: 1961-1967 Published online on: 17 June 2020
Article Open Access

Correlation of changes in serum S100β, NSE and inflammatory factor levels with MMSE and MoCA in intracranial tumor patients with cognitive impairment

Danfeng Yu, Boyi Liu, Guoquan Jiang, Shiwen Pei, Huan Pan

Pages: 1968-1972 Published online on: 17 June 2020
Article

A robust method for the rapid detection of microsatellite instability in colorectal cancer

Lin Zhao, Guangyu Shan, Lei Li, Yang Yu, Gang Cheng, Xu Zheng

Pages: 1982-1988 Published online on: 05 June 2020
Article

STAT3 is a key molecule in the oncogenic behavior of diffuse intrinsic pontine glioma

Jinju Park, Woochan Lee, Sangil Yun, Saet Pyoul Kim, Kyung Hyun Kim, Jong‑Il Kim, Seung‑Ki Kim, Kyu‑Chang Wang, Ji Yeoun Lee

Pages: 1989-1998 Published online on: 05 June 2020
Article

Tumor DNA hypomethylation of LINE‑1 is associated with low tumor grade of breast cancer in Tunisian patients

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Journal Cover

August-2020
Volume 20 Issue 2

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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