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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2020 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Phenotypic screening using large‑scale genomic libraries to identify drug targets for the treatment of cancer (Review)

Mitsuo Sato
Pages: 3617-3626
Published online on: 03 April 2020

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Review

IEO model: A novel concept describing the complete metastatic process in the liver microenvironment (Review)

Lu Wang, Yinan Sun, Minxiao Yi, Weiheng Zhao, Xianglin Yuan
Pages: 3627-3633
Published online on: 10 April 2020

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Article Open Access

Aging‑associated genes TNFRSF12A and CHI3L1 contribute to thyroid cancer: An evidence for the involvement of hypoxia as a driver

Meng Lian, Hongbao Cao, Ancha Baranova, Kamil Can Kural, Lizhen Hou, Shizhi He, Qing Shao, Jugao Fang
Pages: 3634-3642
Published online on: 10 April 2020

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Article Open Access

Effect and mechanism of miR‑146a on malignant biological behaviors of lung adenocarcinoma cell line

Fang Yuan, Suyun Zhang, Wenying Xie, Sheng Yang, Tingyan Lin, Xiangqi Chen
Pages: 3643-3652
Published online on: 23 March 2020

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Article Open Access

Nucleobindin‑2 enhances the epithelial‑mesenchymal transition in renal cell carcinoma

Ran Tao, Wen‑Bin Niu, Peng‑Hui Dou, Shao‑Bin Ni, Yi‑Peng Yu, Li‑Cheng Cai, Xin‑Yuan Wang, Shu‑Yi Li, Cheng Zhang, Zhen‑Guo Luo
Pages: 3653-3664
Published online on: 10 April 2020

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Article Open Access

Claudin 18.2 expression in esophageal adenocarcinoma and its potential impact on future treatment strategies

Valeska Moentenich, Florian Gebauer, Erdem Comut, Armin Tuchscherer, Christiane Bruns, Wolfgang Schroeder, Reinhard Buettner, Hakan Alakus, Heike Loeser, Thomas Zander, Alexander Quaas
Pages: 3665-3670
Published online on: 07 April 2020

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Article Open Access

Oncogenic roles of the cholesterol metabolite 25‑hydroxycholesterol in bladder cancer

Chen Wang, Haowei He, Wennian Fang
Pages: 3671-3676
Published online on: 27 March 2020

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Article Open Access

Bioinformatics analyses and biological function of lncRNA ZFPM2‑AS1 and ZFPM2 gene in hepatocellular carcinoma

Yi Luo, Xiaojun Wang, Ling Ma, Zhihua Ma, Shen Li, Xiaoyu Fang, Xiangyu Ma
Pages: 3677-3686
Published online on: 27 March 2020

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Article Open Access

Association of angiogenesis and inflammation‑related gene functional polymorphisms with early‑stage breast cancer prognosis

Erika Korobeinikova, Rasa Ugenskiene, Ruta Insodaite, Viktoras Rudzianskas, Evelina Jaselske, Lina Poskiene, Elona Juozaityte
Pages: 3687-3700
Published online on: 07 April 2020

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Article Open Access

MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Pages: 3701-3710
Published online on: 27 March 2020

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Article Open Access

NGAL protects in nasopharyngeal carcinoma by inducing apoptosis and blocking epithelial‑mesenchymal transition

Ying Guo, Jianhua Zhai, Jing Zhang, Huifang Zhou
Pages: 3711-3718
Published online on: 10 April 2020

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Article Open Access

lncRNA PICART1 alleviates progression of cervical cancer by upregulating TCF21

Yunxia Zhao, Xiuxian Dong, Rong Hou
Pages: 3719-3724
Published online on: 27 March 2020

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Article Open Access

circ_103809 promotes breast cancer progression by regulating the PI3K/AKT signaling pathway Retraction in /10.3892/ol.2025.15176

Xiaoli Qiu, Qinghua Wang, Huiping Song, Di Shao, Jie Xue
Pages: 3725-3730
Published online on: 02 April 2020

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Article Open Access

Comprehensive analysis of the long non‑coding RNA‑associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor

Zifeng Liu, Wenbo Zhao, Yuqing Ren, Chang Liu, Xun Liu, Jian Xiao
Pages: 3731-3742
Published online on: 31 March 2020

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Article Open Access

Marked epithelial to mesenchymal transition in surgical margins of oral cancer‑an in vitro study

Milos Lazarevic, Maja Milosevic, Drago Jelovac, Sanja Milenkovic, Zvezdana Tepavcevic, Federica Baldan, Tijana Suboticki, Bosko Toljic, Dijana Trisic, Miroslav Dragovic, Giuseppe Damante, Jelena Milasin
Pages: 3743-3750
Published online on: 29 March 2020

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Article Open Access

Overexpression of LBX2 associated with tumor progression and poor prognosis in colorectal cancer

Xiaodong Huang, Yujie Yang, Chao Yang, Huali Li, Huangrong Cheng, Yongbin Zheng
Pages: 3751-3760
Published online on: 27 March 2020

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Article Open Access

Advantages of gross total resection in patients with astrocytoma: A population‑based study

Hua Mao, Xianguo Li, Weipu Mao
Pages: 3761-3774
Published online on: 06 April 2020

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Article Open Access

Prognostic value of quantitative FDG‑PET in the prediction of survival and local recurrence for patients with advanced oral cancer treated with superselective intra‑arterial chemoradiotherapy

Tomoyuki Oyama, Yoichiro Hosokawa, Kazuki Abe, Kazuki Hasegawa, Roman Fukui, Masahiko Aoki, Wataru Kobayashi
Pages: 3775-3780
Published online on: 27 March 2020

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Article Open Access

Downregulation of FHL1 protein in glioma inhibits tumor growth through PI3K/AKT signaling

San‑Zhong Li, Yi‑Yang Hu, Jun‑Long Zhao, Jian Zang, Zhou Fei, Hua Han, Hong‑Yan Qin
Pages: 3781-3788
Published online on: 27 March 2020

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Article Open Access

Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency. Corrigendum in /10.3892/ol.2020.11907

Jinhuan Wang, Zhaoyi Miao, Yanan Jiang, Ping Zou, Weiming Li, Xiaoqiong Tang, Yangyang Lv, Donghui Xing, Shi Chen, Fengchun Yang, Mingjiang Xu, Zeng Cao, Haitao Wang, Zhigang Zhao
Pages: 3789-3798
Published online on: 27 March 2020

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Article Open Access

Identification of differentially expressed genes and biological pathways in para‑carcinoma tissues of HCC with different metastatic potentials

Yan Liu, Mingming Deng, Yimeng Wang, Huiqin Wang, Changping Li, Hao Wu
Pages: 3799-3814
Published online on: 29 March 2020

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Article Open Access

Identification of potential cervical cancer serum biomarkers in Thai patients

Siriporn Keeratichamroen, Pantipa Subhasitanont, Daranee Chokchaichamnankit, Churat Weeraphan, Kittirat Saharat, Narongrit Sritana, Nuttavut Kantathavorn, Kriangpol Wiriyaukaradecha, Thaniya Sricharunrat, N. Monique Paricharttanakul, Chirayu Auewarakul, Jisnuson Svasti, Chantragan Srisomsap
Pages: 3815-3826
Published online on: 07 April 2020

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Article Open Access

Gene silencing of indoleamine 2,3‑dioxygenase 1 inhibits lung cancer growth by suppressing T‑cell exhaustion

Ke Shang, Zhigang Wang, Yinying Hu, Yanqin Huang, Keng Yuan, Yanrong Yu
Pages: 3827-3838
Published online on: 27 March 2020

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Article Open Access

Effects of high‑intensity focused ultrasound treatment on peripancreatic arterial and venous blood vessels in pancreatic cancer

Xiaoyin Guo, Hui Zhu, Kun Zhou, Chengbing Jin, Yang Yang, Jun Zhang, Wei Yang, Lifeng Ran, Dobromir Dimitrov Dimitrov
Pages: 3839-3850
Published online on: 03 April 2020

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Article Open Access

A comparison of computed tomography with magnetic resonance imaging for the diagnosis of thoracic extramedullary hemopoiesis in patients with leukemia: A non‑inferiority retrospective diagnostic study

Zhiyu Ling, Yingyi Xia, Qiuxia Wang
Pages: 3851-3858
Published online on: 06 April 2020

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Article Open Access

Predictive value of tumor genetic alteration profiling for chemotherapy and EGFR‑TKI treatment in advanced NSCLC

Wei Jiang, Aiping Zeng, Ruiling Ning, Wenhua Zhao, Cuiyun Su, Huilin Wang, Shaozhang Zhou, Qitao Yu
Pages: 3859-3870
Published online on: 01 April 2020

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Article Open Access

Survivin expression as an independent predictor of overall survival in malignant peritoneal mesothelioma

Guozun Zhang, Dong‑Liang Yang, Guoqi Zheng, Yufei Liang
Pages: 3871-3880
Published online on: 02 April 2020

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Article Open Access

Positron emission tomography/computed tomography using 2‑deoxy‑2‑fluoro‑18‑fluoro‑D‑glucose peri‑tumoral halo uptake layer method outperforms magnetic resonance imaging and ultrasound methods in tumor size measurement of breast cancer

Yingzhe Wu, Yuezhong Lu, Chentao Xu, Bin Lin
Pages: 3881-3888
Published online on: 29 March 2020

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Article Open Access

Cytoskeleton-associated membrane protein 4 is upregulated in tumor tissues and is associated with clinicopathological characteristics and prognosis in hepatocellular carcinoma

Zhi-Yong Chen, Ting Wang, Xia Gan, Si-Hai Chen, Yu-Ting He, Yu-Qi Wang, Kun-He Zhang
Pages: 3889-3898
Published online on: 31 March 2020

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Article Open Access

Clinical and prognostic significance of MYH11 in lung cancer

Meng‑Jun Nie, Xiao‑Ting Pan, He‑Yun Tao, Meng‑Jun Xu, Shen‑Lin Liu, Wei Sun, Jian Wu, Xi Zou
Pages: 3899-3906
Published online on: 27 March 2020

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Article Open Access

p62 manipulation affects chlorin e6‑mediated photodynamic therapy efficacy in colorectal cancer cell lines

Ju Hee Kim, In‑Wook Kim
Pages: 3907-3916
Published online on: 07 April 2020

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Article Open Access

Prognostic ability of DNA‑binding protein inhibitor ID‑1 expression in patients with oral squamous cell carcinoma

Jian Chen, Fan Zhang, Dong Wang, Zhongjun Yang, Shaohua Liu, Zuoqing Dong
Pages: 3917-3922
Published online on: 02 April 2020

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Article Open Access

MicroRNA‑758 acts as a tumor inhibitor in colorectal cancer through targeting PAX6 and regulating PI3K/AKT pathway

Xinli Zhang, Jumei Xu, Hongchang Zhang, Jilan Sun, Na Li, Xianyu Huang
Pages: 3923-3930
Published online on: 06 April 2020

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Article Open Access

Effect of video‑assisted thoracoscopic surgery on pain stress indicators NO, IL‑1β and IL‑6 in the treatment of mediastinal tumor in children

Bo Zhai, Yonghong Zhang, Zhenliang Chen, Fang Yang, Xiangyang Dong, Zhongjian Chen, Yazhou Cui, Penggao Wang, Lei Shi, Wenbo Yu
Pages: 3931-3936
Published online on: 06 April 2020

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Article Open Access

Association of lncRNA‑p53 regulatory network (lincRNA‑p21, lincRNA‑ROR and MALAT1) and p53 with the clinicopathological features of colorectal primary lesions and tumors

Vahid Chaleshi, Shiva Irani, Masoud Alebouyeh, Reza Mirfakhraie, Hamid Asadzadeh Aghdaei
Pages: 3937-3949
Published online on: 07 April 2020

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Article Open Access

Icaritin enhances the efficacy of cetuximab against triple‑negative breast cancer cells

Li Yin, Xiao‑Wei Qi, Xun‑Zhou Liu, Ze‑Yu Yang, Rui‑Li Cai, Hong‑Juan Cui, Li Chen, Shi‑Cang Yu
Pages: 3950-3958
Published online on: 31 March 2020

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Article Open Access

High expression of lncRNA-SNHG7 is associated with poor prognosis in hepatocellular carcinoma

An Shen, Jinping Ma, Xiaolin Hu, Xinjiang Cui
Pages: 3959-3963
Published online on: 27 March 2020

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Article Open Access

Analysis of post‑operative efficacy and pharyngeal fistula healing in patients with laryngeal cancer treated with post‑operative enteral nutrition support nursing combined with early oral feeding

Aitao Lin, Jin Ye, Zhiyuan Wang, Pei Li
Pages: 3964-3970
Published online on: 01 April 2020

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Article Open Access

Expression of yhwaz and gene regulation network in hepatocellular carcinoma Erratum in /10.3892/ol.2020.11996

Yi Lin, Ling Sun, Xiaolei Ye
Pages: 3971-3981
Published online on: 27 March 2020

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Article Open Access

Myeloid‑derived suppressor cells infiltration in non‑small‑cell lung cancer tumor and MAGE‑A4 and NY‑ESO‑1 expression

Zhenbo Hou, Xiao Liang, Xinmei Wang, Ziqiang Zhou, Guilan Shi
Pages: 3982-3992
Published online on: 31 March 2020

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Article Open Access

Upregulation of lncRNA AGAP2‑AS1 is an independent predictor of poor survival in patients with clear cell renal carcinoma

Lei Gao, Anning Zhao, Xiaolu Wang
Pages: 3993-4001
Published online on: 27 March 2020

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Article Open Access

Profiling of serum metabolites in advanced colon cancer using liquid chromatography‑mass spectrometry

Yang Zhang, Yechao Du, Zheyu Song, Suoning Liu, Wei Li, Daguang Wang, Jian Suo
Pages: 4002-4010
Published online on: 03 April 2020

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Article Open Access

Clinical and prognostic association of oncogene cadherin 11 in gastric cancer

Qiang Wang, Yingdong Jia, Xudong Peng, Chunhong Li
Pages: 4011-4023
Published online on: 10 April 2020

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Article Open Access

Epididymal protein 3A is upregulated and promotes cell proliferation in non‑small cell lung cancer

Guangbin Li, Xing Tong, Liangbin Pan, Haitao Huang, Haitao Ma, Yu Feng
Pages: 4024-4030
Published online on: 07 April 2020

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Article Open Access

Clinical, pathological and treatment factors associated with the survival of patients with pulmonary sarcomatoid carcinoma

Xiaohong Liang, Yinan Cheng, Zijiang Yuan, Zhengping Yan, Quqing Li, Yuan Huang, Gaohua Feng
Pages: 4031-4039
Published online on: 23 March 2020

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Article Open Access

A putative competing endogenous RNA network in cisplatin‑resistant lung adenocarcinoma cells identifying potentially rewarding research targets

Yepeng Li, Shiqing Huang, Zhongheng Wei, Bo Yang
Pages: 4040-4052
Published online on: 27 March 2020

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Article Open Access

Elevated mRNA expression levels of DLGAP5 are associated with poor prognosis in breast cancer

Tao Xu, Menglu Dong, Hanning Li, Rui Zhang, Xingrui Li
Pages: 4053-4065
Published online on: 10 April 2020

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Article Open Access

Survival analysis following microwave ablation or surgical resection in patients with hepatocellular carcinoma conforming to the Milan criteria

Quan Sun, Jingxiang Shi, Chaoyi Ren, Zhi Du, Guiming Shu, Yijun Wang
Pages: 4066-4076
Published online on: 10 April 2020

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Article Open Access

Translation regulatory long non‑coding RNA 1 represents a potential prognostic biomarker for colorectal cancer

Weijia Wang, Xiaolong Tang, Hui Qu, Qingsi He
Pages: 4077-4087
Published online on: 10 April 2020

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Article Open Access

A challenging therapeutic method for breast cancer: Non‑lipolytic endoscopic axillary surgery through periareolar incisions

Yongqianq Chen, Jianhua Xu, Yinghui Liang, Xiaoshan Zeng, Shuangta Xu
Pages: 4088-4092
Published online on: 31 March 2020

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Article Open Access

Development and validation of a novel nomogram for predicting the prognosis of patients with resected pancreatic adenocarcinoma

Hu Ren, Chao‑Rui Wu, Saderbieke Aimaiti, Cheng‑Feng Wang
Pages: 4093-4105
Published online on: 29 March 2020

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Article

Mass spectrometry‑based iTRAQ analysis of serum markers in patients with pancreatic cancer

Kai Jia, Xia Zhao, Xueyi Dang
Pages: 4106-4114
Published online on: 29 March 2020

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Article

GRIM‑19 deficiency promotes clear cell renal cell carcinoma progression and is associated with high TNM stage and Fuhrman grade

Naimeng Yan, Xue Feng, Sixiong Jiang, Weibin Sun, Ming‑Zhong Sun, Shuqing Liu
Pages: 4115-4121
Published online on: 31 March 2020

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Article

Validation and proposed modification of the 8th edition American Joint Committee on Cancer staging system for patients with esophageal neuroendocrine neoplasms: Evaluation of a revised lymph node classification

Haihong Wang, Yaobing Chen, Guoliang Pi, Ying Zhu, Shengli Yang, Hong Mei, Zhenyu Lin, Tao Zhang
Pages: 4122-4132
Published online on: 27 March 2020

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Article

Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma

Ekene Nweke, Monde Ntwasa, Martin Brand, John Devar, Martin Smith, Geoffrey Candy
Pages: 4133-4141
Published online on: 23 March 2020

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Article

Combination of pembrolizumab and 125I attenuates the aggressiveness of non‑small cell lung cancer

Shuo Wang, Jun Zhang, Fan‑Jie Meng, Yi‑Jie Yan, Bin Wang, Zhi‑Yu Guan
Pages: 4142-4150
Published online on: 03 April 2020

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Article Open Access

Decreased biochemical progression in patients with castration‑resistant prostate cancer using a novel mefenamic acid anti‑inflammatory therapy: A randomized controlled trial

José Guzman‑Esquivel, Martha A. Mendoza‑Hernandez, Daniel Tiburcio‑Jimenez, Oscar N. Avila‑Zamora, Josuel Delgado‑Enciso, Luis De‑Leon‑Zaragoza, Juan C. Casarez‑Price, Iram P. Rodriguez‑Sanchez, Margarita L. Martinez‑Fierro, Carmen Meza‑Robles, Alejandro Barocio‑Acosta, Luz M. Baltazar‑Rodriguez, Sergio A. Zaizar‑Fregoso, Jorge E. Plata‑Florenzano, Iván Delgado‑Enciso
Pages: 4151-4160
Published online on: 03 April 2020

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Article

Inhibition of miR‑18a‑3p reduces proliferation of mesothelioma cells and sensitizes them to cisplatin

Rui Suzuki, Vishwa Jeet Amatya, Kei Kushitani, Yuichiro Kai, Takahiro Kambara, Yutaro Fujii, Yukio Takeshima
Pages: 4161-4168
Published online on: 01 April 2020

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Article

Genetic alterations in epidermal growth factor receptor‑tyrosine kinase inhibitor‑naïve non‑small cell lung carcinoma

Takumi Yamaura, Satoshi Muto, Hayato Mine, Hironori Takagi, Masayuki Watanabe, Yuki Ozaki, Takuya Inoue, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hiroyuki Suzuki
Pages: 4169-4176
Published online on: 08 April 2020

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Article

Curcumin inhibits epithelial‑mesenchymal transition in oral cancer cells via c‑Met blockade

Yuichi Ohnishi, Tsukasa Sakamoto, Li Zhengguang, Hiroki Yasui, Hiroyuki Hamada, Hirohito Kubo, Masahiro Nakajima
Pages: 4177-4182
Published online on: 07 April 2020

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Detection of circulating tumor cells in patients with laryngeal cancer using ScreenCell: Comparative pre- and post-operative analysis and association with prognosis

Maria Ida Rizzo, Massimo Ralli, Chiara Nicolazzo, Angela Gradilone, Raffaella Carletti, Cira Di Gioia, Marco De Vincentiis, Antonio Greco
Pages: 4183-4188
Published online on: 10 April 2020

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LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703

Xin Wang, Xinghua Gan, Chengcheng Liu, Wenfeng Zhang
Pages: 4189-4194
Published online on: 27 March 2020

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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