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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2020 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Phenotypic screening using large‑scale genomic libraries to identify drug targets for the treatment of cancer (Review)

Mitsuo Sato
Pages: 3617-3626
Published online on: 03 April 2020

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Review

IEO model: A novel concept describing the complete metastatic process in the liver microenvironment (Review)

Lu Wang, Yinan Sun, Minxiao Yi, Weiheng Zhao, Xianglin Yuan
Pages: 3627-3633
Published online on: 10 April 2020

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Article Open Access

Aging‑associated genes TNFRSF12A and CHI3L1 contribute to thyroid cancer: An evidence for the involvement of hypoxia as a driver

Meng Lian, Hongbao Cao, Ancha Baranova, Kamil Can Kural, Lizhen Hou, Shizhi He, Qing Shao, Jugao Fang
Pages: 3634-3642
Published online on: 10 April 2020

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Article Open Access

Effect and mechanism of miR‑146a on malignant biological behaviors of lung adenocarcinoma cell line

Fang Yuan, Suyun Zhang, Wenying Xie, Sheng Yang, Tingyan Lin, Xiangqi Chen
Pages: 3643-3652
Published online on: 23 March 2020

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Article Open Access

Nucleobindin‑2 enhances the epithelial‑mesenchymal transition in renal cell carcinoma

Ran Tao, Wen‑Bin Niu, Peng‑Hui Dou, Shao‑Bin Ni, Yi‑Peng Yu, Li‑Cheng Cai, Xin‑Yuan Wang, Shu‑Yi Li, Cheng Zhang, Zhen‑Guo Luo
Pages: 3653-3664
Published online on: 10 April 2020

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Article Open Access

Claudin 18.2 expression in esophageal adenocarcinoma and its potential impact on future treatment strategies

Valeska Moentenich, Florian Gebauer, Erdem Comut, Armin Tuchscherer, Christiane Bruns, Wolfgang Schroeder, Reinhard Buettner, Hakan Alakus, Heike Loeser, Thomas Zander, Alexander Quaas
Pages: 3665-3670
Published online on: 07 April 2020

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Article Open Access

Oncogenic roles of the cholesterol metabolite 25‑hydroxycholesterol in bladder cancer

Chen Wang, Haowei He, Wennian Fang
Pages: 3671-3676
Published online on: 27 March 2020

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Article Open Access

Bioinformatics analyses and biological function of lncRNA ZFPM2‑AS1 and ZFPM2 gene in hepatocellular carcinoma

Yi Luo, Xiaojun Wang, Ling Ma, Zhihua Ma, Shen Li, Xiaoyu Fang, Xiangyu Ma
Pages: 3677-3686
Published online on: 27 March 2020

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Article Open Access

Association of angiogenesis and inflammation‑related gene functional polymorphisms with early‑stage breast cancer prognosis

Erika Korobeinikova, Rasa Ugenskiene, Ruta Insodaite, Viktoras Rudzianskas, Evelina Jaselske, Lina Poskiene, Elona Juozaityte
Pages: 3687-3700
Published online on: 07 April 2020

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Article Open Access

MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Pages: 3701-3710
Published online on: 27 March 2020

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Article Open Access

NGAL protects in nasopharyngeal carcinoma by inducing apoptosis and blocking epithelial‑mesenchymal transition

Ying Guo, Jianhua Zhai, Jing Zhang, Huifang Zhou
Pages: 3711-3718
Published online on: 10 April 2020

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Article Open Access

lncRNA PICART1 alleviates progression of cervical cancer by upregulating TCF21

Yunxia Zhao, Xiuxian Dong, Rong Hou
Pages: 3719-3724
Published online on: 27 March 2020

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Article Open Access

circ_103809 promotes breast cancer progression by regulating the PI3K/AKT signaling pathway Retraction in /10.3892/ol.2025.15176

Xiaoli Qiu, Qinghua Wang, Huiping Song, Di Shao, Jie Xue
Pages: 3725-3730
Published online on: 02 April 2020

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Article Open Access

Comprehensive analysis of the long non‑coding RNA‑associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor

Zifeng Liu, Wenbo Zhao, Yuqing Ren, Chang Liu, Xun Liu, Jian Xiao
Pages: 3731-3742
Published online on: 31 March 2020

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Article Open Access

Marked epithelial to mesenchymal transition in surgical margins of oral cancer‑an in vitro study

Milos Lazarevic, Maja Milosevic, Drago Jelovac, Sanja Milenkovic, Zvezdana Tepavcevic, Federica Baldan, Tijana Suboticki, Bosko Toljic, Dijana Trisic, Miroslav Dragovic, Giuseppe Damante, Jelena Milasin
Pages: 3743-3750
Published online on: 29 March 2020

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Article Open Access

Overexpression of LBX2 associated with tumor progression and poor prognosis in colorectal cancer

Xiaodong Huang, Yujie Yang, Chao Yang, Huali Li, Huangrong Cheng, Yongbin Zheng
Pages: 3751-3760
Published online on: 27 March 2020

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Article Open Access

Advantages of gross total resection in patients with astrocytoma: A population‑based study

Hua Mao, Xianguo Li, Weipu Mao
Pages: 3761-3774
Published online on: 06 April 2020

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Article Open Access

Prognostic value of quantitative FDG‑PET in the prediction of survival and local recurrence for patients with advanced oral cancer treated with superselective intra‑arterial chemoradiotherapy

Tomoyuki Oyama, Yoichiro Hosokawa, Kazuki Abe, Kazuki Hasegawa, Roman Fukui, Masahiko Aoki, Wataru Kobayashi
Pages: 3775-3780
Published online on: 27 March 2020

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Article Open Access

Downregulation of FHL1 protein in glioma inhibits tumor growth through PI3K/AKT signaling

San‑Zhong Li, Yi‑Yang Hu, Jun‑Long Zhao, Jian Zang, Zhou Fei, Hua Han, Hong‑Yan Qin
Pages: 3781-3788
Published online on: 27 March 2020

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Article Open Access

Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency. Corrigendum in /10.3892/ol.2020.11907

Jinhuan Wang, Zhaoyi Miao, Yanan Jiang, Ping Zou, Weiming Li, Xiaoqiong Tang, Yangyang Lv, Donghui Xing, Shi Chen, Fengchun Yang, Mingjiang Xu, Zeng Cao, Haitao Wang, Zhigang Zhao
Pages: 3789-3798
Published online on: 27 March 2020

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Article Open Access

Identification of differentially expressed genes and biological pathways in para‑carcinoma tissues of HCC with different metastatic potentials

Yan Liu, Mingming Deng, Yimeng Wang, Huiqin Wang, Changping Li, Hao Wu
Pages: 3799-3814
Published online on: 29 March 2020

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Article Open Access

Identification of potential cervical cancer serum biomarkers in Thai patients

Siriporn Keeratichamroen, Pantipa Subhasitanont, Daranee Chokchaichamnankit, Churat Weeraphan, Kittirat Saharat, Narongrit Sritana, Nuttavut Kantathavorn, Kriangpol Wiriyaukaradecha, Thaniya Sricharunrat, N. Monique Paricharttanakul, Chirayu Auewarakul, Jisnuson Svasti, Chantragan Srisomsap
Pages: 3815-3826
Published online on: 07 April 2020

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Article Open Access

Gene silencing of indoleamine 2,3‑dioxygenase 1 inhibits lung cancer growth by suppressing T‑cell exhaustion

Ke Shang, Zhigang Wang, Yinying Hu, Yanqin Huang, Keng Yuan, Yanrong Yu
Pages: 3827-3838
Published online on: 27 March 2020

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Article Open Access

Effects of high‑intensity focused ultrasound treatment on peripancreatic arterial and venous blood vessels in pancreatic cancer

Xiaoyin Guo, Hui Zhu, Kun Zhou, Chengbing Jin, Yang Yang, Jun Zhang, Wei Yang, Lifeng Ran, Dobromir Dimitrov Dimitrov
Pages: 3839-3850
Published online on: 03 April 2020

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Article Open Access

A comparison of computed tomography with magnetic resonance imaging for the diagnosis of thoracic extramedullary hemopoiesis in patients with leukemia: A non‑inferiority retrospective diagnostic study

Zhiyu Ling, Yingyi Xia, Qiuxia Wang
Pages: 3851-3858
Published online on: 06 April 2020

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Article Open Access

Predictive value of tumor genetic alteration profiling for chemotherapy and EGFR‑TKI treatment in advanced NSCLC

Wei Jiang, Aiping Zeng, Ruiling Ning, Wenhua Zhao, Cuiyun Su, Huilin Wang, Shaozhang Zhou, Qitao Yu
Pages: 3859-3870
Published online on: 01 April 2020

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Article Open Access

Survivin expression as an independent predictor of overall survival in malignant peritoneal mesothelioma

Guozun Zhang, Dong‑Liang Yang, Guoqi Zheng, Yufei Liang
Pages: 3871-3880
Published online on: 02 April 2020

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Article Open Access

Positron emission tomography/computed tomography using 2‑deoxy‑2‑fluoro‑18‑fluoro‑D‑glucose peri‑tumoral halo uptake layer method outperforms magnetic resonance imaging and ultrasound methods in tumor size measurement of breast cancer

Yingzhe Wu, Yuezhong Lu, Chentao Xu, Bin Lin
Pages: 3881-3888
Published online on: 29 March 2020

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Article Open Access

Cytoskeleton-associated membrane protein 4 is upregulated in tumor tissues and is associated with clinicopathological characteristics and prognosis in hepatocellular carcinoma

Zhi-Yong Chen, Ting Wang, Xia Gan, Si-Hai Chen, Yu-Ting He, Yu-Qi Wang, Kun-He Zhang
Pages: 3889-3898
Published online on: 31 March 2020

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Article Open Access

Clinical and prognostic significance of MYH11 in lung cancer

Meng‑Jun Nie, Xiao‑Ting Pan, He‑Yun Tao, Meng‑Jun Xu, Shen‑Lin Liu, Wei Sun, Jian Wu, Xi Zou
Pages: 3899-3906
Published online on: 27 March 2020

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Article Open Access

p62 manipulation affects chlorin e6‑mediated photodynamic therapy efficacy in colorectal cancer cell lines

Ju Hee Kim, In‑Wook Kim
Pages: 3907-3916
Published online on: 07 April 2020

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Article Open Access

Prognostic ability of DNA‑binding protein inhibitor ID‑1 expression in patients with oral squamous cell carcinoma

Jian Chen, Fan Zhang, Dong Wang, Zhongjun Yang, Shaohua Liu, Zuoqing Dong
Pages: 3917-3922
Published online on: 02 April 2020

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Article Open Access

MicroRNA‑758 acts as a tumor inhibitor in colorectal cancer through targeting PAX6 and regulating PI3K/AKT pathway

Xinli Zhang, Jumei Xu, Hongchang Zhang, Jilan Sun, Na Li, Xianyu Huang
Pages: 3923-3930
Published online on: 06 April 2020

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Article Open Access

Effect of video‑assisted thoracoscopic surgery on pain stress indicators NO, IL‑1β and IL‑6 in the treatment of mediastinal tumor in children

Bo Zhai, Yonghong Zhang, Zhenliang Chen, Fang Yang, Xiangyang Dong, Zhongjian Chen, Yazhou Cui, Penggao Wang, Lei Shi, Wenbo Yu
Pages: 3931-3936
Published online on: 06 April 2020

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Article Open Access

Association of lncRNA‑p53 regulatory network (lincRNA‑p21, lincRNA‑ROR and MALAT1) and p53 with the clinicopathological features of colorectal primary lesions and tumors

Vahid Chaleshi, Shiva Irani, Masoud Alebouyeh, Reza Mirfakhraie, Hamid Asadzadeh Aghdaei
Pages: 3937-3949
Published online on: 07 April 2020

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Article Open Access

Icaritin enhances the efficacy of cetuximab against triple‑negative breast cancer cells

Li Yin, Xiao‑Wei Qi, Xun‑Zhou Liu, Ze‑Yu Yang, Rui‑Li Cai, Hong‑Juan Cui, Li Chen, Shi‑Cang Yu
Pages: 3950-3958
Published online on: 31 March 2020

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Article Open Access

High expression of lncRNA-SNHG7 is associated with poor prognosis in hepatocellular carcinoma

An Shen, Jinping Ma, Xiaolin Hu, Xinjiang Cui
Pages: 3959-3963
Published online on: 27 March 2020

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Article Open Access

Analysis of post‑operative efficacy and pharyngeal fistula healing in patients with laryngeal cancer treated with post‑operative enteral nutrition support nursing combined with early oral feeding

Aitao Lin, Jin Ye, Zhiyuan Wang, Pei Li
Pages: 3964-3970
Published online on: 01 April 2020

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Article Open Access

Expression of yhwaz and gene regulation network in hepatocellular carcinoma Erratum in /10.3892/ol.2020.11996

Yi Lin, Ling Sun, Xiaolei Ye
Pages: 3971-3981
Published online on: 27 March 2020

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Article Open Access

Myeloid‑derived suppressor cells infiltration in non‑small‑cell lung cancer tumor and MAGE‑A4 and NY‑ESO‑1 expression

Zhenbo Hou, Xiao Liang, Xinmei Wang, Ziqiang Zhou, Guilan Shi
Pages: 3982-3992
Published online on: 31 March 2020

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Article Open Access

Upregulation of lncRNA AGAP2‑AS1 is an independent predictor of poor survival in patients with clear cell renal carcinoma

Lei Gao, Anning Zhao, Xiaolu Wang
Pages: 3993-4001
Published online on: 27 March 2020

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Article Open Access

Profiling of serum metabolites in advanced colon cancer using liquid chromatography‑mass spectrometry

Yang Zhang, Yechao Du, Zheyu Song, Suoning Liu, Wei Li, Daguang Wang, Jian Suo
Pages: 4002-4010
Published online on: 03 April 2020

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Article Open Access

Clinical and prognostic association of oncogene cadherin 11 in gastric cancer

Qiang Wang, Yingdong Jia, Xudong Peng, Chunhong Li
Pages: 4011-4023
Published online on: 10 April 2020

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Article Open Access

Epididymal protein 3A is upregulated and promotes cell proliferation in non‑small cell lung cancer

Guangbin Li, Xing Tong, Liangbin Pan, Haitao Huang, Haitao Ma, Yu Feng
Pages: 4024-4030
Published online on: 07 April 2020

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Article Open Access

Clinical, pathological and treatment factors associated with the survival of patients with pulmonary sarcomatoid carcinoma

Xiaohong Liang, Yinan Cheng, Zijiang Yuan, Zhengping Yan, Quqing Li, Yuan Huang, Gaohua Feng
Pages: 4031-4039
Published online on: 23 March 2020

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Article Open Access

A putative competing endogenous RNA network in cisplatin‑resistant lung adenocarcinoma cells identifying potentially rewarding research targets

Yepeng Li, Shiqing Huang, Zhongheng Wei, Bo Yang
Pages: 4040-4052
Published online on: 27 March 2020

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Article Open Access

Elevated mRNA expression levels of DLGAP5 are associated with poor prognosis in breast cancer

Tao Xu, Menglu Dong, Hanning Li, Rui Zhang, Xingrui Li
Pages: 4053-4065
Published online on: 10 April 2020

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Article Open Access

Survival analysis following microwave ablation or surgical resection in patients with hepatocellular carcinoma conforming to the Milan criteria

Quan Sun, Jingxiang Shi, Chaoyi Ren, Zhi Du, Guiming Shu, Yijun Wang
Pages: 4066-4076
Published online on: 10 April 2020

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Article Open Access

Translation regulatory long non‑coding RNA 1 represents a potential prognostic biomarker for colorectal cancer

Weijia Wang, Xiaolong Tang, Hui Qu, Qingsi He
Pages: 4077-4087
Published online on: 10 April 2020

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Article Open Access

A challenging therapeutic method for breast cancer: Non‑lipolytic endoscopic axillary surgery through periareolar incisions

Yongqianq Chen, Jianhua Xu, Yinghui Liang, Xiaoshan Zeng, Shuangta Xu
Pages: 4088-4092
Published online on: 31 March 2020

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Article Open Access

Development and validation of a novel nomogram for predicting the prognosis of patients with resected pancreatic adenocarcinoma

Hu Ren, Chao‑Rui Wu, Saderbieke Aimaiti, Cheng‑Feng Wang
Pages: 4093-4105
Published online on: 29 March 2020

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Article

Mass spectrometry‑based iTRAQ analysis of serum markers in patients with pancreatic cancer

Kai Jia, Xia Zhao, Xueyi Dang
Pages: 4106-4114
Published online on: 29 March 2020

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Article

GRIM‑19 deficiency promotes clear cell renal cell carcinoma progression and is associated with high TNM stage and Fuhrman grade

Naimeng Yan, Xue Feng, Sixiong Jiang, Weibin Sun, Ming‑Zhong Sun, Shuqing Liu
Pages: 4115-4121
Published online on: 31 March 2020

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Article

Validation and proposed modification of the 8th edition American Joint Committee on Cancer staging system for patients with esophageal neuroendocrine neoplasms: Evaluation of a revised lymph node classification

Haihong Wang, Yaobing Chen, Guoliang Pi, Ying Zhu, Shengli Yang, Hong Mei, Zhenyu Lin, Tao Zhang
Pages: 4122-4132
Published online on: 27 March 2020

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Article

Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma

Ekene Nweke, Monde Ntwasa, Martin Brand, John Devar, Martin Smith, Geoffrey Candy
Pages: 4133-4141
Published online on: 23 March 2020

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Article

Combination of pembrolizumab and 125I attenuates the aggressiveness of non‑small cell lung cancer

Shuo Wang, Jun Zhang, Fan‑Jie Meng, Yi‑Jie Yan, Bin Wang, Zhi‑Yu Guan
Pages: 4142-4150
Published online on: 03 April 2020

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Article Open Access

Decreased biochemical progression in patients with castration‑resistant prostate cancer using a novel mefenamic acid anti‑inflammatory therapy: A randomized controlled trial

José Guzman‑Esquivel, Martha A. Mendoza‑Hernandez, Daniel Tiburcio‑Jimenez, Oscar N. Avila‑Zamora, Josuel Delgado‑Enciso, Luis De‑Leon‑Zaragoza, Juan C. Casarez‑Price, Iram P. Rodriguez‑Sanchez, Margarita L. Martinez‑Fierro, Carmen Meza‑Robles, Alejandro Barocio‑Acosta, Luz M. Baltazar‑Rodriguez, Sergio A. Zaizar‑Fregoso, Jorge E. Plata‑Florenzano, Iván Delgado‑Enciso
Pages: 4151-4160
Published online on: 03 April 2020

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Article

Inhibition of miR‑18a‑3p reduces proliferation of mesothelioma cells and sensitizes them to cisplatin

Rui Suzuki, Vishwa Jeet Amatya, Kei Kushitani, Yuichiro Kai, Takahiro Kambara, Yutaro Fujii, Yukio Takeshima
Pages: 4161-4168
Published online on: 01 April 2020

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Article

Genetic alterations in epidermal growth factor receptor‑tyrosine kinase inhibitor‑naïve non‑small cell lung carcinoma

Takumi Yamaura, Satoshi Muto, Hayato Mine, Hironori Takagi, Masayuki Watanabe, Yuki Ozaki, Takuya Inoue, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hiroyuki Suzuki
Pages: 4169-4176
Published online on: 08 April 2020

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Article

Curcumin inhibits epithelial‑mesenchymal transition in oral cancer cells via c‑Met blockade

Yuichi Ohnishi, Tsukasa Sakamoto, Li Zhengguang, Hiroki Yasui, Hiroyuki Hamada, Hirohito Kubo, Masahiro Nakajima
Pages: 4177-4182
Published online on: 07 April 2020

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Article

Detection of circulating tumor cells in patients with laryngeal cancer using ScreenCell: Comparative pre- and post-operative analysis and association with prognosis

Maria Ida Rizzo, Massimo Ralli, Chiara Nicolazzo, Angela Gradilone, Raffaella Carletti, Cira Di Gioia, Marco De Vincentiis, Antonio Greco
Pages: 4183-4188
Published online on: 10 April 2020

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LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703

Xin Wang, Xinghua Gan, Chengcheng Liu, Wenfeng Zhang
Pages: 4189-4194
Published online on: 27 March 2020

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑molero, Paz Rodríguez‑cundín, Javier Llorca, Inés Gómez‑aceb, Trinidad Dierssen‑sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Article Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Article Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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