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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2020 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Phenotypic screening using large‑scale genomic libraries to identify drug targets for the treatment of cancer (Review)

Mitsuo Sato
Pages: 3617-3626
Published online on: 03 April 2020

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Review

IEO model: A novel concept describing the complete metastatic process in the liver microenvironment (Review)

Lu Wang, Yinan Sun, Minxiao Yi, Weiheng Zhao, Xianglin Yuan
Pages: 3627-3633
Published online on: 10 April 2020

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Article Open Access

Aging‑associated genes TNFRSF12A and CHI3L1 contribute to thyroid cancer: An evidence for the involvement of hypoxia as a driver

Meng Lian, Hongbao Cao, Ancha Baranova, Kamil Can Kural, Lizhen Hou, Shizhi He, Qing Shao, Jugao Fang
Pages: 3634-3642
Published online on: 10 April 2020

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Article Open Access

Effect and mechanism of miR‑146a on malignant biological behaviors of lung adenocarcinoma cell line

Fang Yuan, Suyun Zhang, Wenying Xie, Sheng Yang, Tingyan Lin, Xiangqi Chen
Pages: 3643-3652
Published online on: 23 March 2020

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Article Open Access

Nucleobindin‑2 enhances the epithelial‑mesenchymal transition in renal cell carcinoma

Ran Tao, Wen‑Bin Niu, Peng‑Hui Dou, Shao‑Bin Ni, Yi‑Peng Yu, Li‑Cheng Cai, Xin‑Yuan Wang, Shu‑Yi Li, Cheng Zhang, Zhen‑Guo Luo
Pages: 3653-3664
Published online on: 10 April 2020

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Article Open Access

Claudin 18.2 expression in esophageal adenocarcinoma and its potential impact on future treatment strategies

Valeska Moentenich, Florian Gebauer, Erdem Comut, Armin Tuchscherer, Christiane Bruns, Wolfgang Schroeder, Reinhard Buettner, Hakan Alakus, Heike Loeser, Thomas Zander, Alexander Quaas
Pages: 3665-3670
Published online on: 07 April 2020

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Article Open Access

Oncogenic roles of the cholesterol metabolite 25‑hydroxycholesterol in bladder cancer

Chen Wang, Haowei He, Wennian Fang
Pages: 3671-3676
Published online on: 27 March 2020

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Article Open Access

Bioinformatics analyses and biological function of lncRNA ZFPM2‑AS1 and ZFPM2 gene in hepatocellular carcinoma

Yi Luo, Xiaojun Wang, Ling Ma, Zhihua Ma, Shen Li, Xiaoyu Fang, Xiangyu Ma
Pages: 3677-3686
Published online on: 27 March 2020

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Article Open Access

Association of angiogenesis and inflammation‑related gene functional polymorphisms with early‑stage breast cancer prognosis

Erika Korobeinikova, Rasa Ugenskiene, Ruta Insodaite, Viktoras Rudzianskas, Evelina Jaselske, Lina Poskiene, Elona Juozaityte
Pages: 3687-3700
Published online on: 07 April 2020

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Article Open Access

MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Pages: 3701-3710
Published online on: 27 March 2020

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Article Open Access

NGAL protects in nasopharyngeal carcinoma by inducing apoptosis and blocking epithelial‑mesenchymal transition

Ying Guo, Jianhua Zhai, Jing Zhang, Huifang Zhou
Pages: 3711-3718
Published online on: 10 April 2020

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Article Open Access

lncRNA PICART1 alleviates progression of cervical cancer by upregulating TCF21

Yunxia Zhao, Xiuxian Dong, Rong Hou
Pages: 3719-3724
Published online on: 27 March 2020

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Article Open Access

circ_103809 promotes breast cancer progression by regulating the PI3K/AKT signaling pathway Retraction in /10.3892/ol.2025.15176

Xiaoli Qiu, Qinghua Wang, Huiping Song, Di Shao, Jie Xue
Pages: 3725-3730
Published online on: 02 April 2020

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Article Open Access

Comprehensive analysis of the long non‑coding RNA‑associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor

Zifeng Liu, Wenbo Zhao, Yuqing Ren, Chang Liu, Xun Liu, Jian Xiao
Pages: 3731-3742
Published online on: 31 March 2020

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Article Open Access

Marked epithelial to mesenchymal transition in surgical margins of oral cancer‑an in vitro study

Milos Lazarevic, Maja Milosevic, Drago Jelovac, Sanja Milenkovic, Zvezdana Tepavcevic, Federica Baldan, Tijana Suboticki, Bosko Toljic, Dijana Trisic, Miroslav Dragovic, Giuseppe Damante, Jelena Milasin
Pages: 3743-3750
Published online on: 29 March 2020

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Article Open Access

Overexpression of LBX2 associated with tumor progression and poor prognosis in colorectal cancer

Xiaodong Huang, Yujie Yang, Chao Yang, Huali Li, Huangrong Cheng, Yongbin Zheng
Pages: 3751-3760
Published online on: 27 March 2020

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Article Open Access

Advantages of gross total resection in patients with astrocytoma: A population‑based study

Hua Mao, Xianguo Li, Weipu Mao
Pages: 3761-3774
Published online on: 06 April 2020

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Article Open Access

Prognostic value of quantitative FDG‑PET in the prediction of survival and local recurrence for patients with advanced oral cancer treated with superselective intra‑arterial chemoradiotherapy

Tomoyuki Oyama, Yoichiro Hosokawa, Kazuki Abe, Kazuki Hasegawa, Roman Fukui, Masahiko Aoki, Wataru Kobayashi
Pages: 3775-3780
Published online on: 27 March 2020

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Article Open Access

Downregulation of FHL1 protein in glioma inhibits tumor growth through PI3K/AKT signaling

San‑Zhong Li, Yi‑Yang Hu, Jun‑Long Zhao, Jian Zang, Zhou Fei, Hua Han, Hong‑Yan Qin
Pages: 3781-3788
Published online on: 27 March 2020

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Article Open Access

Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency. Corrigendum in /10.3892/ol.2020.11907

Jinhuan Wang, Zhaoyi Miao, Yanan Jiang, Ping Zou, Weiming Li, Xiaoqiong Tang, Yangyang Lv, Donghui Xing, Shi Chen, Fengchun Yang, Mingjiang Xu, Zeng Cao, Haitao Wang, Zhigang Zhao
Pages: 3789-3798
Published online on: 27 March 2020

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Article Open Access

Identification of differentially expressed genes and biological pathways in para‑carcinoma tissues of HCC with different metastatic potentials

Yan Liu, Mingming Deng, Yimeng Wang, Huiqin Wang, Changping Li, Hao Wu
Pages: 3799-3814
Published online on: 29 March 2020

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Article Open Access

Identification of potential cervical cancer serum biomarkers in Thai patients

Siriporn Keeratichamroen, Pantipa Subhasitanont, Daranee Chokchaichamnankit, Churat Weeraphan, Kittirat Saharat, Narongrit Sritana, Nuttavut Kantathavorn, Kriangpol Wiriyaukaradecha, Thaniya Sricharunrat, N. Monique Paricharttanakul, Chirayu Auewarakul, Jisnuson Svasti, Chantragan Srisomsap
Pages: 3815-3826
Published online on: 07 April 2020

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Article Open Access

Gene silencing of indoleamine 2,3‑dioxygenase 1 inhibits lung cancer growth by suppressing T‑cell exhaustion

Ke Shang, Zhigang Wang, Yinying Hu, Yanqin Huang, Keng Yuan, Yanrong Yu
Pages: 3827-3838
Published online on: 27 March 2020

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Article Open Access

Effects of high‑intensity focused ultrasound treatment on peripancreatic arterial and venous blood vessels in pancreatic cancer

Xiaoyin Guo, Hui Zhu, Kun Zhou, Chengbing Jin, Yang Yang, Jun Zhang, Wei Yang, Lifeng Ran, Dobromir Dimitrov Dimitrov
Pages: 3839-3850
Published online on: 03 April 2020

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Article Open Access

A comparison of computed tomography with magnetic resonance imaging for the diagnosis of thoracic extramedullary hemopoiesis in patients with leukemia: A non‑inferiority retrospective diagnostic study

Zhiyu Ling, Yingyi Xia, Qiuxia Wang
Pages: 3851-3858
Published online on: 06 April 2020

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Article Open Access

Predictive value of tumor genetic alteration profiling for chemotherapy and EGFR‑TKI treatment in advanced NSCLC

Wei Jiang, Aiping Zeng, Ruiling Ning, Wenhua Zhao, Cuiyun Su, Huilin Wang, Shaozhang Zhou, Qitao Yu
Pages: 3859-3870
Published online on: 01 April 2020

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Article Open Access

Survivin expression as an independent predictor of overall survival in malignant peritoneal mesothelioma

Guozun Zhang, Dong‑Liang Yang, Guoqi Zheng, Yufei Liang
Pages: 3871-3880
Published online on: 02 April 2020

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Article Open Access

Positron emission tomography/computed tomography using 2‑deoxy‑2‑fluoro‑18‑fluoro‑D‑glucose peri‑tumoral halo uptake layer method outperforms magnetic resonance imaging and ultrasound methods in tumor size measurement of breast cancer

Yingzhe Wu, Yuezhong Lu, Chentao Xu, Bin Lin
Pages: 3881-3888
Published online on: 29 March 2020

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Article Open Access

Cytoskeleton-associated membrane protein 4 is upregulated in tumor tissues and is associated with clinicopathological characteristics and prognosis in hepatocellular carcinoma

Zhi-Yong Chen, Ting Wang, Xia Gan, Si-Hai Chen, Yu-Ting He, Yu-Qi Wang, Kun-He Zhang
Pages: 3889-3898
Published online on: 31 March 2020

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Article Open Access

Clinical and prognostic significance of MYH11 in lung cancer

Meng‑Jun Nie, Xiao‑Ting Pan, He‑Yun Tao, Meng‑Jun Xu, Shen‑Lin Liu, Wei Sun, Jian Wu, Xi Zou
Pages: 3899-3906
Published online on: 27 March 2020

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Article Open Access

p62 manipulation affects chlorin e6‑mediated photodynamic therapy efficacy in colorectal cancer cell lines

Ju Hee Kim, In‑Wook Kim
Pages: 3907-3916
Published online on: 07 April 2020

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Article Open Access

Prognostic ability of DNA‑binding protein inhibitor ID‑1 expression in patients with oral squamous cell carcinoma

Jian Chen, Fan Zhang, Dong Wang, Zhongjun Yang, Shaohua Liu, Zuoqing Dong
Pages: 3917-3922
Published online on: 02 April 2020

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Article Open Access

MicroRNA‑758 acts as a tumor inhibitor in colorectal cancer through targeting PAX6 and regulating PI3K/AKT pathway

Xinli Zhang, Jumei Xu, Hongchang Zhang, Jilan Sun, Na Li, Xianyu Huang
Pages: 3923-3930
Published online on: 06 April 2020

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Article Open Access

Effect of video‑assisted thoracoscopic surgery on pain stress indicators NO, IL‑1β and IL‑6 in the treatment of mediastinal tumor in children

Bo Zhai, Yonghong Zhang, Zhenliang Chen, Fang Yang, Xiangyang Dong, Zhongjian Chen, Yazhou Cui, Penggao Wang, Lei Shi, Wenbo Yu
Pages: 3931-3936
Published online on: 06 April 2020

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Article Open Access

Association of lncRNA‑p53 regulatory network (lincRNA‑p21, lincRNA‑ROR and MALAT1) and p53 with the clinicopathological features of colorectal primary lesions and tumors

Vahid Chaleshi, Shiva Irani, Masoud Alebouyeh, Reza Mirfakhraie, Hamid Asadzadeh Aghdaei
Pages: 3937-3949
Published online on: 07 April 2020

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Article Open Access

Icaritin enhances the efficacy of cetuximab against triple‑negative breast cancer cells

Li Yin, Xiao‑Wei Qi, Xun‑Zhou Liu, Ze‑Yu Yang, Rui‑Li Cai, Hong‑Juan Cui, Li Chen, Shi‑Cang Yu
Pages: 3950-3958
Published online on: 31 March 2020

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Article Open Access

High expression of lncRNA-SNHG7 is associated with poor prognosis in hepatocellular carcinoma

An Shen, Jinping Ma, Xiaolin Hu, Xinjiang Cui
Pages: 3959-3963
Published online on: 27 March 2020

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Article Open Access

Analysis of post‑operative efficacy and pharyngeal fistula healing in patients with laryngeal cancer treated with post‑operative enteral nutrition support nursing combined with early oral feeding

Aitao Lin, Jin Ye, Zhiyuan Wang, Pei Li
Pages: 3964-3970
Published online on: 01 April 2020

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Article Open Access

Expression of yhwaz and gene regulation network in hepatocellular carcinoma Erratum in /10.3892/ol.2020.11996

Yi Lin, Ling Sun, Xiaolei Ye
Pages: 3971-3981
Published online on: 27 March 2020

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Article Open Access

Myeloid‑derived suppressor cells infiltration in non‑small‑cell lung cancer tumor and MAGE‑A4 and NY‑ESO‑1 expression

Zhenbo Hou, Xiao Liang, Xinmei Wang, Ziqiang Zhou, Guilan Shi
Pages: 3982-3992
Published online on: 31 March 2020

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Article Open Access

Upregulation of lncRNA AGAP2‑AS1 is an independent predictor of poor survival in patients with clear cell renal carcinoma

Lei Gao, Anning Zhao, Xiaolu Wang
Pages: 3993-4001
Published online on: 27 March 2020

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Article Open Access

Profiling of serum metabolites in advanced colon cancer using liquid chromatography‑mass spectrometry

Yang Zhang, Yechao Du, Zheyu Song, Suoning Liu, Wei Li, Daguang Wang, Jian Suo
Pages: 4002-4010
Published online on: 03 April 2020

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Article Open Access

Clinical and prognostic association of oncogene cadherin 11 in gastric cancer

Qiang Wang, Yingdong Jia, Xudong Peng, Chunhong Li
Pages: 4011-4023
Published online on: 10 April 2020

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Article Open Access

Epididymal protein 3A is upregulated and promotes cell proliferation in non‑small cell lung cancer

Guangbin Li, Xing Tong, Liangbin Pan, Haitao Huang, Haitao Ma, Yu Feng
Pages: 4024-4030
Published online on: 07 April 2020

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Article Open Access

Clinical, pathological and treatment factors associated with the survival of patients with pulmonary sarcomatoid carcinoma

Xiaohong Liang, Yinan Cheng, Zijiang Yuan, Zhengping Yan, Quqing Li, Yuan Huang, Gaohua Feng
Pages: 4031-4039
Published online on: 23 March 2020

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Article Open Access

A putative competing endogenous RNA network in cisplatin‑resistant lung adenocarcinoma cells identifying potentially rewarding research targets

Yepeng Li, Shiqing Huang, Zhongheng Wei, Bo Yang
Pages: 4040-4052
Published online on: 27 March 2020

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Article Open Access

Elevated mRNA expression levels of DLGAP5 are associated with poor prognosis in breast cancer

Tao Xu, Menglu Dong, Hanning Li, Rui Zhang, Xingrui Li
Pages: 4053-4065
Published online on: 10 April 2020

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Article Open Access

Survival analysis following microwave ablation or surgical resection in patients with hepatocellular carcinoma conforming to the Milan criteria

Quan Sun, Jingxiang Shi, Chaoyi Ren, Zhi Du, Guiming Shu, Yijun Wang
Pages: 4066-4076
Published online on: 10 April 2020

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Article Open Access

Translation regulatory long non‑coding RNA 1 represents a potential prognostic biomarker for colorectal cancer

Weijia Wang, Xiaolong Tang, Hui Qu, Qingsi He
Pages: 4077-4087
Published online on: 10 April 2020

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Article Open Access

A challenging therapeutic method for breast cancer: Non‑lipolytic endoscopic axillary surgery through periareolar incisions

Yongqianq Chen, Jianhua Xu, Yinghui Liang, Xiaoshan Zeng, Shuangta Xu
Pages: 4088-4092
Published online on: 31 March 2020

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Article Open Access

Development and validation of a novel nomogram for predicting the prognosis of patients with resected pancreatic adenocarcinoma

Hu Ren, Chao‑Rui Wu, Saderbieke Aimaiti, Cheng‑Feng Wang
Pages: 4093-4105
Published online on: 29 March 2020

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Article

Mass spectrometry‑based iTRAQ analysis of serum markers in patients with pancreatic cancer

Kai Jia, Xia Zhao, Xueyi Dang
Pages: 4106-4114
Published online on: 29 March 2020

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Article

GRIM‑19 deficiency promotes clear cell renal cell carcinoma progression and is associated with high TNM stage and Fuhrman grade

Naimeng Yan, Xue Feng, Sixiong Jiang, Weibin Sun, Ming‑Zhong Sun, Shuqing Liu
Pages: 4115-4121
Published online on: 31 March 2020

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Article

Validation and proposed modification of the 8th edition American Joint Committee on Cancer staging system for patients with esophageal neuroendocrine neoplasms: Evaluation of a revised lymph node classification

Haihong Wang, Yaobing Chen, Guoliang Pi, Ying Zhu, Shengli Yang, Hong Mei, Zhenyu Lin, Tao Zhang
Pages: 4122-4132
Published online on: 27 March 2020

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Article

Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma

Ekene Nweke, Monde Ntwasa, Martin Brand, John Devar, Martin Smith, Geoffrey Candy
Pages: 4133-4141
Published online on: 23 March 2020

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Article

Combination of pembrolizumab and 125I attenuates the aggressiveness of non‑small cell lung cancer

Shuo Wang, Jun Zhang, Fan‑Jie Meng, Yi‑Jie Yan, Bin Wang, Zhi‑Yu Guan
Pages: 4142-4150
Published online on: 03 April 2020

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Article Open Access

Decreased biochemical progression in patients with castration‑resistant prostate cancer using a novel mefenamic acid anti‑inflammatory therapy: A randomized controlled trial

José Guzman‑Esquivel, Martha A. Mendoza‑Hernandez, Daniel Tiburcio‑Jimenez, Oscar N. Avila‑Zamora, Josuel Delgado‑Enciso, Luis De‑Leon‑Zaragoza, Juan C. Casarez‑Price, Iram P. Rodriguez‑Sanchez, Margarita L. Martinez‑Fierro, Carmen Meza‑Robles, Alejandro Barocio‑Acosta, Luz M. Baltazar‑Rodriguez, Sergio A. Zaizar‑Fregoso, Jorge E. Plata‑Florenzano, Iván Delgado‑Enciso
Pages: 4151-4160
Published online on: 03 April 2020

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Article

Inhibition of miR‑18a‑3p reduces proliferation of mesothelioma cells and sensitizes them to cisplatin

Rui Suzuki, Vishwa Jeet Amatya, Kei Kushitani, Yuichiro Kai, Takahiro Kambara, Yutaro Fujii, Yukio Takeshima
Pages: 4161-4168
Published online on: 01 April 2020

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Article

Genetic alterations in epidermal growth factor receptor‑tyrosine kinase inhibitor‑naïve non‑small cell lung carcinoma

Takumi Yamaura, Satoshi Muto, Hayato Mine, Hironori Takagi, Masayuki Watanabe, Yuki Ozaki, Takuya Inoue, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hiroyuki Suzuki
Pages: 4169-4176
Published online on: 08 April 2020

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Article

Curcumin inhibits epithelial‑mesenchymal transition in oral cancer cells via c‑Met blockade

Yuichi Ohnishi, Tsukasa Sakamoto, Li Zhengguang, Hiroki Yasui, Hiroyuki Hamada, Hirohito Kubo, Masahiro Nakajima
Pages: 4177-4182
Published online on: 07 April 2020

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Detection of circulating tumor cells in patients with laryngeal cancer using ScreenCell: Comparative pre- and post-operative analysis and association with prognosis

Maria Ida Rizzo, Massimo Ralli, Chiara Nicolazzo, Angela Gradilone, Raffaella Carletti, Cira Di Gioia, Marco De Vincentiis, Antonio Greco
Pages: 4183-4188
Published online on: 10 April 2020

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LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703

Xin Wang, Xinghua Gan, Chengcheng Liu, Wenfeng Zhang
Pages: 4189-4194
Published online on: 27 March 2020

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May-2026 Volume 31 Issue 5

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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