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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2019 Volume 17 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Liquid biopsy for lung cancer immunotherapy (Review)

Liang‑Liang Cai, Jie Wang
Pages: 4751-4760
Published online on: 19 March 2019

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Review

Anticancer effect of ursolic acid via mitochondria‑dependent pathways (Review)

Xue‑Min Feng, Xiu‑Lan Su
Pages: 4761-4767
Published online on: 19 March 2019

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Article Open Access

Apatinib combined with chemotherapy in patients with previously treated advanced breast cancer: An observational study

Anjie Zhu, Peng Yuan, Jiayu Wang, Ying Fan, Yang Luo, Ruigang Cai, Pin Zhang, Qing Li, Fei Ma, Binghe Xu
Pages: 4768-4778
Published online on: 02 April 2019

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Article Open Access

Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer

Manuel Nolasco‑Quiroga, Marisol Rosas‑Díaz, José Moreno, Ricardo Godínez‑Aguilar, María José López‑Ibarra, Patricia Piña‑Sánchez, Isabel Alvarado‑Cabrero, Gerardo Vázquez‑Gómez, Leticia Rocha‑Zavaleta, Diego Arenas‑Aranda, Fabio Salamanca‑Gómez
Pages: 4779-4786
Published online on: 15 March 2019

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Article Open Access

Analysis of the role of DAMTC in lung adenocarcinoma cells based on the DNA microarrays

Binliang Wang, Yuanyuan Cai, Yiming Kong, Xiaobo Li, Haiwei Fu, Song Zhang, Tianwei Zhang
Pages: 4787-4794
Published online on: 15 March 2019

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Article Open Access

Alantolactone induces gastric cancer BGC‑823 cell apoptosis by regulating reactive oxygen species generation and the AKT signaling pathway

Xin Zhang, Hong‑Ming Zhang
Pages: 4795-4802
Published online on: 19 March 2019

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Article Open Access

Circular RNA ATXN7 is upregulated in non‑small cell lung cancer and promotes disease progression

Qi Huang, Shaodong Wang, Xiao Li, Fan Yang, Changjiang Feng, Kaize Zhong, Mantang Qiu, Jun Wang
Pages: 4803-4810
Published online on: 19 March 2019

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Article Open Access

CD151 confers metastatic potential to clear cell sarcoma of the soft tissue in animal model

Keisuke Kawashima, Chiemi Saigo, Yusuke Kito, Yuki Hanamatsu, Yuki Egawa, Tamotsu Takeuchi
Pages: 4811-4818
Published online on: 19 March 2019

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Article Open Access

MicroRNA‑9 enhances chemotherapy sensitivity of glioma to TMZ by suppressing TOPO II via the NF‑κB signaling pathway

Qingla Li, Yingnan Chang, Luyan Mu, Yuwen Song
Pages: 4819-4826
Published online on: 18 March 2019

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Article Open Access

Capsaicin induces apoptosis and autophagy in human melanoma cells

Haihan Chu, Meng Li, Xiuchun Wang
Pages: 4827-4834
Published online on: 03 April 2019

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Article Open Access

Talin2 regulates invasion of human breast cancer MDA‑MB‑231 cells via alteration of the tumor microenvironment

Zhengwei Wen, Yingfan Liang, Shengming Deng, Lilin Zou, Xiaofan Xie, Jifeng Yang, Yiwei Wu
Pages: 4835-4842
Published online on: 21 March 2019

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Article Open Access

Tumor growth under rhGM‑CSF application in an orthotopic rodent glioma model

Thomas Linsenmann, Anna Jawork, Thomas Westermaier, György Homola, Camelia Maria Monoranu, Giles Hamilton Vince, Almuth Friederike Kessler, Ralf‑Ingo Ernestus, Mario Löhr
Pages: 4843-4850
Published online on: 21 March 2019

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Article Open Access

Evaluation of the benefit of post‑mastectomy radiotherapy in patients with early‑stage breast cancer: A propensity score matching study

Wenjie Shi, Youhong Luo, Dongkang Zhao, Hao Huang, Weiyi Pang
Pages: 4851-4858
Published online on: 29 March 2019

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Article Open Access

Correlation of p16 and cyclin D1 expression with the incidence and prognosis of cardiac carcinoma

Haoxun Wang, Jing Wang, Bingbo Zhao
Pages: 4859-4864
Published online on: 26 March 2019

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Article Open Access

Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma

Jinpeng Jia, Pei Yin, Xingpeng Zhang, Fei Yang, Ge Song, Wenzhi Bi, Gang Han, Meng Xu, Wei Wang, Xiaoque Zheng
Pages: 4865-4870
Published online on: 13 March 2019

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Article Open Access

Expression of miRNA-146b-5p in patients with thyroid cancer in combination with Hashimoto's disease and its clinical significance

Ninglei Li, Xiaolong Liu, Luzhe Han, Rui Zhou, Jian Yan, Guoxiang Zhao, Lixin Liu
Pages: 4871-4876
Published online on: 20 March 2019

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Article Open Access

Increased CX3CL1 mRNA expression level is a positive prognostic factor in patients with lung adenocarcinoma

Jian Liu, Yan Li, Xiaoqin Zhu, Qing Li, Xiaohong Liang, Jun Xie, Song Hu, Wanda Peng, Chong Li
Pages: 4877-4890
Published online on: 03 April 2019

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Article Open Access

Impact of EMT in stage IIIB/IV NSCLC treated with erlotinib and bevacizumab when compared with cisplatin, gemcitabine and bevacizumab

Matthias Villalobos, Piotr Czapiewski, Niels Reinmuth, Jürgen R. Fischer, Stefan Andreas, Cornelius Kortsik, Monika Serke, Martin Wolf, Petra Neuser, Alexander Reuss, Philipp A. Schnabel, Michael Thomas
Pages: 4891-4900
Published online on: 15 March 2019

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Article Open Access

Study on value of ultrasonic elastography in diagnosis of clinical staging of cervical cancer and efficacy evaluation of radiotherapy

Yingying Zhang, Yuanyuan Yan, Yuejie Yang
Pages: 4901-4906
Published online on: 26 March 2019

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Article Open Access

KMT5A promotes metastasis of clear cell renal cell carcinoma through reducing cadherin‑1 expression

Zhen‑Zhong Lin, De‑Song Ming, Ya‑Bin Chen, Jian‑Ming Zhang, Hui‑Hua Chen, Jian‑Jia Jiang, Zhi‑Shan Zhang
Pages: 4907-4913
Published online on: 19 March 2019

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Article Open Access

NOTCH2/NOTCH3/DLL3/MAML1/ADAM17 signaling network is associated with ovarian cancer

Dongyu Jia, Jesse Underwood, Qiuping Xu, Qian Xie
Pages: 4914-4920
Published online on: 19 March 2019

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Article Open Access

Particle stability and structure on the peritoneal surface in pressurized intra‑peritoneal aerosol chemotherapy (PIPAC) analysed by electron microscopy: First evidence of a new physical concept for PIPAC

Tanja Khosrawipour, Justyna Schubert, Veria Khosrawipour, Haris Chaudhry, Jakub Grzesiak, Mohamed Arafkas, Agata Mikolajczyk
Pages: 4921-4927
Published online on: 19 March 2019

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Article Open Access

Long non‑coding RNA NEF inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells by inhibiting Wnt/β‑catenin signaling

Xiangyan Cui, Ning Fang, Yu Cui, Dong Xiao, Xin Wang
Pages: 4928-4934
Published online on: 15 March 2019

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Article Open Access

Overexpression of ZEB2‑AS1 lncRNA is associated with poor clinical outcomes in acute myeloid leukemia

Xiaolan Shi, Jiao Li, Liang Ma, Lijun Wen, Qinrong Wang, Hong Yao, Changgeng Ruan, Depei Wu, Xinyou Zhang, Suning Chen
Pages: 4935-4947
Published online on: 15 March 2019

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Article Open Access

High TNF‑α and/or p38MAPK expression predicts a favourable prognosis in patients with T1N0M0 hepatocellular carcinoma: An immunohistochemical study Corrigendum in /10.3892/ol.2019.10781

Mao Zhang, Jie Hu, Haoran Li, Shun Zhang, Weiyu Hu, Liqun Wu, Bing Han
Pages: 4948-4956
Published online on: 27 March 2019

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Article Open Access

HIT000218960 promotes gastric cancer cell proliferation and migration through upregulation of HMGA2 expression

Leitao Sun, Jieru Yu, Peipei Wang, Minhe Shen, Shanming Ruan
Pages: 4957-4963
Published online on: 21 March 2019

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Article Open Access

Effect of lincRNA-p21 targeting HIF-1α on biological functions of liver cancer cells

Yibiao Ye, Yaorong Peng, Yanshan Li, Chunxia Liu, Yunxiuxiu Xu, Wenbin Li
Pages: 4964-4968
Published online on: 28 March 2019

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Article Open Access

Long non‑coding RNA‑neighboring enhancer of FOXA2 inhibits the migration and invasion of small cell lung carcinoma cells by downregulating transforming growth factor‑β1

Lei Wu, Pan Wang
Pages: 4969-4975
Published online on: 15 March 2019

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Article Open Access

TP53BP2 decreases cell proliferation and induces autophagy in neuroblastoma cell lines

Yi Pang, Lianhong Pan, Yonghui Zhang, Guiyuan Liu
Pages: 4976-4984
Published online on: 15 March 2019

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Article Open Access

PAX3 is a biomarker and prognostic factor in melanoma: Database mining

Yong Liu, Shengnan Cui, Wenbin Li, Yiding Zhao, Xiaoning Yan, Jianqin Xu
Pages: 4985-4993
Published online on: 18 March 2019

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Article Open Access

RNA sequencing uncovers the key long non‑coding RNAs and potential molecular mechanism contributing to XAV939‑mediated inhibition of non‑small cell lung cancer

Haixiang Yu, Zhifeng Han, Zhenan Xu, Chong An, Lei Xu, Hua Xin
Pages: 4994-5004
Published online on: 27 March 2019

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Article Open Access

LINK‑A lncRNA functions in the metastasis of osteosarcoma by upregulating HIF1α

Boming Zhao, Kebin Liu, Lin Cai
Pages: 5005-5011
Published online on: 21 March 2019

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Article Open Access

Co‑inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo

Jiansong Wang, Huaijun Ji, Qiang Zhu, Xinshuang Yu, Juan Du, Zhongmin Jiang
Pages: 5012-5022
Published online on: 19 March 2019

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Article Open Access

The effects of BRCA1 expression on the chemosensitivity of gastric cancer cells to platinum agents

Geon Kim, Jisu Kim, Su‑Young Han, In Gyu Hwang, Hee Sung Kim, Hyeyoung Min
Pages: 5023-5029
Published online on: 19 March 2019

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Article Open Access

Ornithine transcarbamylase downregulation is associated with poor prognosis in hepatocellular carcinoma

Lin He, Xuefei Cai, Shengtao Cheng, Hongzhong Zhou, Zhenzhen Zhang, Jihua Ren, Fang Ren, Qiuxia Yang, Nana Tao, Juan Chen
Pages: 5030-5038
Published online on: 21 March 2019

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Article Open Access

Support of acute lymphoblastic leukemia cells by nonmalignant bone marrow stromal cells

Sana Usmani, Urmila Sivagnanalingam, Olena Tkachenko, Leti Nunez, Jessica C. Shand, Craig A. Mullen
Pages: 5039-5049
Published online on: 22 March 2019

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Article Open Access

Effect of gastrointestinal microbiome and its diversity on the expression of tumor‑infiltrating lymphocytes in breast cancer

Jiajie Shi, Cuizhi Geng, Meixiang Sang, Wei Gao, Sainan Li, Shan Yang, Zheng Li
Pages: 5050-5056
Published online on: 22 March 2019

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Article Open Access

Identification of a 13‑gene‑based classifier as a potential biomarker to predict the effects of fluorouracil‑based chemotherapy in colorectal cancer

Zuhuan Gan, Qiyuan Zou, Yan Lin, Zihai Xu, Zhong Huang, Zhichao Chen, Yufeng Lv
Pages: 5057-5063
Published online on: 19 March 2019

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Article Open Access

Selectively high efficacy of eribulin against high‑grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck

Yutaka Kobayashi, Hiroko Kitahara, Mariko Hirai, Akira Tanaka, Rei Jokaji, Kazuhiko Kobayashi, George Bou‑Gharios, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 5064-5072
Published online on: 19 March 2019

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Article Open Access

TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma

Youji Yan, Zhongjun Chen, Yixiang Liao, Jiajie Zhou
Pages: 5073-5079
Published online on: 19 March 2019

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Article Open Access

Overexpression of EPAC2 reduces the invasion of glioma cells via MMP‑2

Ming Jiang, Yan Zhuang, Wang‑Cun Zu, Lei Jiao, Seidu A. Richard, Shiming Zhang
Pages: 5080-5086
Published online on: 29 March 2019

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Article Open Access

miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma Retraction in /10.3892/ol.2026.15822

Yuexiang Niu, Gongen Tang
Pages: 5087-5093
Published online on: 13 March 2019

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Article Open Access

Interleukin‑35 is associated with the tumorigenesis and progression of prostate cancer

Jialin Zhu, Xueling Yang, Yan Wang, Haonan Zhang, Zhi Guo
Pages: 5094-5102
Published online on: 03 April 2019

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Article Open Access

Effects of knockout of lincRNA‑p21 on the proliferation, migration and invasion ability of HepG2 liver cancer cells

Tongshan Wang, Jun Liu, Suihui Li, Zhengang Yuan, Xiangzhong Huang
Pages: 5103-5107
Published online on: 01 April 2019

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Article Open Access

miRNA-99a inhibits cell invasion and migration in liver cancer by directly targeting HOXA1

Changming Tao, Huiling Sun, Weiwei Sang, Shanshan Li
Pages: 5108-5114
Published online on: 29 March 2019

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Article Open Access

Expression and correlation of miR‑124 and miR‑126 in breast cancer

Fanfan Li
Pages: 5115-5119
Published online on: 22 March 2019

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Article Open Access

Effect of lncRNA ZEB1-AS1 on proliferation, invasion and apoptosis of glioma U87 cells

Wei Zhang, Lijun Xiong
Pages: 5120-5124
Published online on: 01 April 2019

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Article

Frequency and significance of epidermal growth factor receptor mutations detected by PCR methods in patients with non‑small cell lung cancer

Eiji Nakajima, Michio Sugita, Kinya Furukawa, Hidenobu Takahashi, Osamu Uchida, Youhei Kawaguchi, Tatsuo Ohira, Jun Matsubayashi, Norihiko Ikeda, Fred R. Hirsch, Wilbur A. Franklin
Pages: 5125-5131
Published online on: 18 March 2019

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Article Open Access

Radiosensitizing effect of 5‑aminolevulinic acid in colorectal cancer in vitro and in vivo

Kazuto Yamada, Yasutoshi Murayama, Yosuke Kamada, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Ryo Morimura, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Takeshi Kubota, Masayoshi Nakanishi, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji
Pages: 5132-5138
Published online on: 29 March 2019

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Article

Prognostic impact of interleukin‑6 and C‑reactive protein on patients with breast cancer

Tatsuo Shimura, Masahiko Shibata, Kenji Gonda, Yuko Murakami, Masaru Noda, Kazunoshin Tachibana, Noriko Abe, Tohru Ohtake
Pages: 5139-5146
Published online on: 21 March 2019

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Article

Differential expression of EphA5 protein in gastric carcinoma and its clinical significance

Wei Zhang, Xue Wei, Shuwei Guo, Jiandong Wang, Jing Liu, Hai Wang
Pages: 5147-5153
Published online on: 19 March 2019

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Article

Fluoroscopy‑guided long intestinal tube placement for the treatment of malignant bowel obstruction

Haiyang Lai, Ketong Wu, Yang Liu, Zhaofei Zeng, Bo Zhang
Pages: 5154-5158
Published online on: 15 March 2019

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Article

High expression of ubiquitin carboxyl‑terminal hydrolase 22 is associated with poor prognosis in hepatitis B virus‑associated liver cancer

Yong Liao, Xingsi Liang, Wenjin Liang, Zeming Li, Yan Wang, Lin Wang, Siqi Zhen, Bo Tang, Zhenran Wang
Pages: 5159-5168
Published online on: 15 March 2019

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Article

CRKII overexpression promotes the in vitro proliferation, migration and invasion potential of murine hepatocarcinoma Hca‑P cells

Zanmei Zhou, Xiuyan Sun, Chunmei Guo, Ming‑Zhong Sun, Shuqing Liu
Pages: 5169-5174
Published online on: 27 March 2019

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Article

Effect of the Nrf2‑ARE signaling pathway on biological characteristics and sensitivity to sunitinib in renal cell carcinoma

Shiliang Ji, Yufeng Xiong, Xingxing Zhao, Yanli Liu, Li Qiang Yu
Pages: 5175-5186
Published online on: 18 March 2019

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Article

Clinicopathological significance of TM4SF5 expression in human hepatocellular carcinoma tissues

Baojin Xu, Wu Lv, Xiaoyan Li, Lina Zhang, Jie Lin
Pages: 5187-5192
Published online on: 03 April 2019

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Article

MicroRNAs aid the assessment of programmed death ligand 1 expression in patients with non‑small cell lung cancer

Anna Grenda, Marcin Nicoś, Michał Szczyrek, Paweł Krawczyk, Tomasz Kucharczyk, Bożena Jarosz, Juliusz Pankowski, Marek Sawicki, Justyna Szumiło, Paulina Bukała, Janusz Milanowski
Pages: 5193-5200
Published online on: 03 April 2019

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Article

miR‑196a regulates the proliferation, invasion and migration of esophageal squamous carcinoma cells by targeting ANXA1

Changmei Hu, Jie Peng, Liang Lv, Xuehong Wang, Yuqian Zhou, Jirong Huo, Deliang Liu
Pages: 5201-5209
Published online on: 22 March 2019

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Article

Downregulation of miR‑136 promotes the progression of osteosarcoma and is associated with the prognosis of patients with osteosarcoma

Yanchen Chu, Xiaoli Hu, Guangfeng Wang, Zhijie Wang, Yanjin Wang
Pages: 5210-5218
Published online on: 01 April 2019

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Case Report

Transformation to small cell lung cancer and activation of KRAS during long‑term erlotinib maintenance in a patient with non‑small cell lung cancer: A case report

Yangchun Gu, Xiang Zhu, Baoshan Cao, Xue Wu, Xiaoling Tong, Yang W. Shao, Li Liang
Pages: 5219-5223
Published online on: 28 March 2019

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Article

In vitro effect of curcumin in combination with chemotherapy drugs in Ph+ acute lymphoblastic leukemia cells

Uriel Francisco Santana‑Bejarano, Lucina Bobadilla‑Morales, Lucero Mendoza‑Maldonado, Elizabeth Torres‑Anguiano, Sinhue Alejandro Brukman‑Jiménez, Cesar Cenobio Barba‑Barba, Jorge Román Corona‑Rivera, Alfredo Corona‑Rivera
Pages: 5224-5240
Published online on: 02 April 2019

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Article

High postoperative neutrophil‑to‑lymphocyte ratio as a poor prognostic marker in patients with upper tract urothelial carcinoma

Kiyoaki Nishihara, Shigetaka Suekane, Kousuke Ueda, Makoto Nakiri, Mitsunori Matsuo, Tsukasa Igawa
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Article

ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK

Shyam K. More, Emilie E. Vomhof‑Dekrey, Marc D. Basson
Pages: 5251-5260
Published online on: 27 March 2019

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Growth inhibitory efficacy of Cornus officinalis in a cell culture model for triple‑negative breast cancer

Nitin T. Telang, Hareesh B. Nair, George Y.C. Wong
Pages: 5261-5266
Published online on: 21 March 2019

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Determination of thymidine phosphorylase expression level facilitates recurrence risk stratification in stage II/III colorectal cancer following adjuvant chemotherapy with oral fluoropyrimidines

Naruji Kugimiya, Eijiro Harada, Yuki Suehiro, Atsushi Suga, Yoshihiro Takemoto, Kimikazu Hamano
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Serum pyruvate dehydrogenase kinase as a prognostic marker for cholangiocarcinoma

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Anti‑breast cancer potential of frullanolide from Grangea maderaspatana plant by inducing apoptosis

Siriphorn Chimplee, Potchanapond Graidist, Theera Srisawat, Suchada Sukrong, Rassanee Bissanum, Kanyanatt Kanokwiroon
Pages: 5283-5291
Published online on: 03 April 2019

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Treatment outcomes of differentiated thyroid cancer with distant metastasis improve by tyrosine kinase inhibitors

Hiroyuki Iwasaki, Haruhiko Yamazaki, Hirotaka Takasaki, Nobuyasu Suganuma, Rika Sakai, Hirotaka Nakayama, Shinsuke Hatori, Soji Toda, Katsuhiko Masudo
Pages: 5292-5300
Published online on: 21 March 2019

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Review Open Access

Tumor progression mechanisms: Insights from the central immune regulation of tissue homeostasis (Review)

Natalya Lisovska, Nasrulla Shanazarov
Pages: 5311-5318
Published online on: 05 April 2019

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Protective effect of gonadotropin‑releasing hormone agonist against chemotherapy‑induced ovarian dysfunction: A meta‑analysis

Fei Zheng, Bin Zhu, Qingjing Feng, Lili Wu, Yuechong Cui, Yumo Liu, Yingqian Wang
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LncRNA GASL1 inhibits growth and promotes expression of apoptosis‑associated proteins in prostate carcinoma cells through GLUT‑1

Zhiqin Li, Hong Liu, Wen Ju, Yifei Xing, Xiaoping Zhang, Jun Yang
Pages: 5327-5334
Published online on: 12 April 2019

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lncRNA MALAT1 overexpression promotes proliferation, migration and invasion of gastric cancer by activating the PI3K/AKT pathway

Kongxi Zhu, Qing Ren, Yanying Zhao
Pages: 5335-5342
Published online on: 15 April 2019

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Sirtuin 1 knockdown inhibits glioma cell proliferation and potentiates temozolomide toxicity via facilitation of reactive oxygen species generation

Hongwu Chen, Rui Lin, Ziheng Zhang, Quantang Wei, Zhiwei Zhong, Jiehao Huang, Yimin Xu
Pages: 5343-5350
Published online on: 09 April 2019

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Human epithelial ovarian cancer cells expressing CD105, CD44 and CD106 surface markers exhibit increased invasive capacity and drug resistance

Jin Zhang, Baozhu Yuan, Huidan Zhang, Hongxia Li
Pages: 5351-5360
Published online on: 05 April 2019

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EGFR, but not COX‑2, protein in resected pancreatic ductal adenocarcinoma is associated with poor survival

Johan Bourghardt Fagman, David Ljungman, Peter Falk, Britt‑Marie Iresjö, Cecilia Engström, Peter Naredi, Kent Lundholm
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Published online on: 05 April 2019

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Design of a liver cancer‑specific selector for the analysis of circulating tumor DNA

Yan Sun, Rui Meng, Heng Tang, Huimin Wang, Xueqin Guo, Yuanyuan Ma, Yun Yang, Xiaoming Wei, Feng Mu, Gang Wu, Jun Wang, Jun Liu, Mingshan Niu, Jun Xue
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Published online on: 12 April 2019

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Integrating radiosensitive genes improves prediction of radiosensitivity or radioresistance in patients with oesophageal cancer

Qiuning Zhang, Zhitong Bing, Jinhui Tian, Xiaohu Wang, Ruifeng Liu, Yi Li, Yarong Kong, Yan Yang
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Published online on: 10 April 2019

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BMP‑2 and miR‑29c in osteosarcoma tissues on proliferation and invasion of osteosarcoma cells

Xueqing Chen, Yingjian Zhang
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Published online on: 08 April 2019

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High expression of PIM2 induces HSC proliferation in myelodysplastic syndromes via the IDH1/HIF1‑α signaling pathway

Zhaoyun Liu, Mengyue Tian, Kai Ding, Hui Liu, Yangyang Wang, Rong Fu
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lncRNA‑NEF is downregulated in osteosarcoma and inhibits cancer cell migration and invasion by downregulating miRNA‑21

Qinglei Yang, Hongying Yu, Qingshui Yin, Xiaoming Hu, Chengcheng Zhang
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Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databases

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IL-6 and miR-1271 expression levels in elderly and young gastric cancer patients and correlation analysis with prognosis

Shixiong Liu, Yun Zhou, Li Zhao, Jing Wang, Rui Ji, Yiqing Wang, Jiyin Wu, Xiang Yan
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Validity of an NGS‑based multiple gene panel in identifying actionable mutations for patients with NSCLC in a Chinese hospital

Wei Cao, Chenghai Yan, Hailong Wang, Tom Tang, Haifeng Wang, Dujuan Liu
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Expression and clinical significance of p73 in Wilms' tumor in children

Yan Ding, Xiaohui Guo, Xinxin Liu, Jitao Li, Ning Li, Cong Xu
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miRNA‑10a promotes cancer cell proliferation in oral squamous cell carcinoma by upregulating GLUT1 and promoting glucose metabolism

Yuan‑Hua Chen, Yu Song, Yan‑Ling Yu, Wei Cheng, Xin Tong
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Clinical efficacy of apatinib in treating metastatic gastric cancer and its effect on IL‑17

Ran Chen, Qi‑Tian Chen, You‑Hong Dong
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Urinary biomarkers for the diagnosis of cervical cancer by quantitative label‑free mass spectrometry analysis

Daranee Chokchaichamnankit, Kamolwan Watcharatanyatip, Pantipa Subhasitanont, Churat Weeraphan, Siriporn Keeratichamroen, Narongrit Sritana, Nuttavut Kantathavorn, Penchatr Diskul‑Na‑Ayudthaya, Kittirat Saharat, Juthamard Chantaraamporn, Chris Verathamjamras, Natacha Phoolcharoen, Kriangpol Wiriyaukaradecha, Nilubol Monique Paricharttanakul, Wandee Udomchaiprasertkul, Thaniya Sricharunrat, Chirayu Auewarakul, Jisnuson Svasti, Chantragan Srisomsap
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Clinical analysis of 21-gene relapse score test in hormone receptor-positive early-stage breast cancer Corrigendum in /10.3892/ol.2021.12572

Lizhe Zhu, Nan Ma, Bin Wang, Can Zhou, Yu Yan, Ke Wang, Jianjun He, Yu Ren
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Clinical diagnostic value of digestive endoscopic narrow-band imaging in early esophageal cancer

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Significance of PD‑L1 clones and C‑MET expression in hepatocellular carcinoma

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Diagnostic value of ultrasound score, color Doppler ultrasound RI and spiral CT for ovarian tumors

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Comparison of diagnostic value of multi‑slice spiral CT and MRI for different pathological stages of prostate cancer

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Correlation analysis between ultrasonography and mammography with other risk factors related to breast cancer

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Effect of dexmedetomidine anesthesia on perioperative levels of TNF-α and IL-6 in patients with ovarian cancer

Maodong Liu, Yusheng Yi, Mingqiang Zhao
Pages: 5517-5522
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Comparison of diagnostic values between CA125 combined with CA199 and ultrasound combined with CT in ovarian cancer

Bingcheng Guo, Wei Lian, Shuai Liu, Yingchun Cao, Jianhua Liu
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Ewing's sarcoma of the cervix: A case report of an unusual diagnosis in pregnancy treated with surgery, adjuvant VIDE and radiotherapy

Anastasios Kyriazoglou, Georgios Tsironis, Michalis Liontos, Alexandra Papakosta, Luisa Mahaira, Nikolaos Thomakos, Georgios Morphopoulos, Irene Papaspyrou, Aristotelis Bamias
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Transcriptomic model‑based lncRNAs and mRNAs serve as independent prognostic indicators in head and neck squamous cell carcinoma

Zhi‑Li Zhang, Li‑Jing Zhao, Lin Xu, Liang Chai, Feng Wang, Ya‑Ping Xu, Shui‑Hong Zhou, Yong Fu
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ceRNA network analysis reveals prognostic markers for glioblastoma

Hao Wang, Heying Zhang, Juan Zeng, Yonggang Tan
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Correlative analysis of miR-34b and p53 with pathological characteristics of NSCLC

Shuai Yang, Hongyan Zhu, Qingping Cheng
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Long non‑coding RNA snaR is involved in the metastasis of liver cancer possibly through TGF‑β1

Zhitian Shi, Dong Wei, Huamei Wu, Jiayun Ge, Xuefen Lei, Zhitang Guo, Renchao Zou, Shufeng Xiao, Tiangen Wu, Ruicheng Ma, Runyao Ai, Lin Wang
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Prognostic implication of ABC transporters and cancer stem cell markers in patients with stage III colon cancer receiving adjuvant FOLFOX‑4 chemotherapy

Song‑Hee Han, Jin Won Kim, Milim Kim, Jee Hyun Kim, Keun‑Wook Lee, Bo‑Hyung Kim, Heung‑Kwon Oh, Duck‑Woo Kim, Sung‑Bum Kang, Hyunchul Kim, Eun Shin
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Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro Retraction in /10.3892/ol.2025.15403 Retraction in /10.3892/ol.2025.15403

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Pages: 5581-5589
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Zihan Xu, Qiao Yang, Xiewan Chen, Linpeng Zheng, Luping Zhang, Yongxin Yu, Mingjing Chen, Qiai You, Jianguo Sun
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MicroRNA profiling of plasma exosomes from patients with ovarian cancer using high‑throughput sequencing

Honghong Zhang, Sijuan Xu, Xiaoli Liu
Pages: 5601-5607
Published online on: 05 April 2019

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Gene set enrichment analysis and meta‑analysis identified 12 key genes regulating and controlling the prognosis of lung adenocarcinoma

Wenwu He, Liangmin Fu, Qunlun Yan, Qiuxi Zhou, Kun Yuan, Linxin Chen, Yongtao Han
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Ping Shi, Zhe Xu, Xin Lei, Feiluore Yibulayin, Alimujiang Wushou
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Expression and significance of PTEN and Claudin‑3 in prostate cancer

Xinglong Ye, Lijing Zhao, Jing Kang
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Diagnostic value of hepatic artery perfusion fraction combined with TGF-β in patients with hepatocellular carcinoma

Qingxu Liu, Yan Gao, Yongxue Wang, Jiexin Du, Qiang Yin, Kewei Shi
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Identification and validation of potential long non‑coding RNA biomarkers in predicting survival of patients with head and neck squamous cell carcinoma

Junyu Li, Yuehua Li, Xiaoping Wu, Ying Li
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Duo Zhi, Kun Zhou, Dahai Yu, Xiaofan Fan, Juan Zhang, Xiang Li, Mei Dong
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Shuigen Zhong, Xiaoxue Zhong, Xiaomei Zhong, Yanlong Liu
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Yazhen Feng, Ji Li, Hushan Wang, Zongsheng Duan
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Effect of adriamycin combined with metformin on biological function of human tongue cancer SSC-15 cells

Jun Zhang
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Lansheng Zhu, Yanling Wang, Rui Li, Aiqun Liu, Xiaoping Zhang, Chunran Zuo, Xiaoting Xu
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miR‑144 suppresses cell proliferation and invasion in gastric cancer through downregulation of activating enhancer‑binding protein 4

Faheim Mushtaq, Jinping Zhang, Jiansheng Li
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miR‑152 may function as an early diagnostic and prognostic biomarker in patients with cervical intraepithelial neoplasia and patients with cervical cancer

Dongmei Yang, Qiumei Zhang
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Epithelial cell transforming sequence 2 expression is associated with the progression of laryngeal squamous cell carcinoma

Lin Zhu, Gang Qin, Lin Ye, Li‑Zhu Jiang, Tie‑Jun Zhou, Bo Luo, Tao‑Yu Wen, Ya‑Lan Liu, Hong‑Yan Chen
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Association of low expression of E‑cadherin and β‑catenin with the progression of early stage human squamous cervical cancer

Jing Jiang, Xinling Li, Xiangmei Yin, Jieying Zhang, Bin Shi
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Biao Li, Yongjie Li, Qiongyu Wang, Fan Li, Fu Li
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Feihu Bai, Fangyun Ba, Yanjie You, Yaning Feng, Wei Tao, Chuanxia Wu, Mengna Jiu, Yongzhan Nie
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Tumor suppressor function of miR‑129‑5p in lung cancer

Ge Li, Jiahang Xie, Jiuhui Wang
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Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration Corrigendum in /10.3892/ol.2026.15698

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MicroRNA‑425 upregulation indicates better prognosis in younger acute myeloid leukemia patients undergoing chemotherapy

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Screening of key miRNAs and evaluation of their diagnostic and prognostic values in nasopharyngeal carcinoma

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Case Report

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Vittorio D'Aguanno, Massimo Ralli, Bruna Cerbelli, Antonio Greco, Marco de Vincentiis
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High expression of microRNA‑500 is associated with poor prognosis in patients with acute myeloid leukemia receiving allogeneic hematopoietic stem cell transplantation

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Article

lncRNAs combine and crosstalk with NSPc1 in ATRA‑induced differentiation of U87 glioma cells

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Understanding the mechanism underlying the acquisition of radioresistance in human prostate cancer cells

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Pages: 5830-5838
Published online on: 05 April 2019

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Correction Open Access

[Corrigendum] Inhibition of cyclooxygenase‑2 sensitizes lung cancer cells to radiation‑induced apoptosis

Zhi‑Qiang Han, Hongwei Liao, Feng Shi, Xiao‑Ping Chen, Hua‑Cheng Hu, Ming‑Qing Tian, Li‑Hua Wang, Songmin Ying
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Published online on: 18 April 2019

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CiteScore Rank: Q3: #233/428 Oncology

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[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

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[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

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Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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Journal Cover
December-2026 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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