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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2019 Volume 17 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Liquid biopsy for lung cancer immunotherapy (Review)

Liang‑Liang Cai, Jie Wang
Pages: 4751-4760
Published online on: 19 March 2019

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Review

Anticancer effect of ursolic acid via mitochondria‑dependent pathways (Review)

Xue‑Min Feng, Xiu‑Lan Su
Pages: 4761-4767
Published online on: 19 March 2019

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Article Open Access

Apatinib combined with chemotherapy in patients with previously treated advanced breast cancer: An observational study

Anjie Zhu, Peng Yuan, Jiayu Wang, Ying Fan, Yang Luo, Ruigang Cai, Pin Zhang, Qing Li, Fei Ma, Binghe Xu
Pages: 4768-4778
Published online on: 02 April 2019

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Article Open Access

Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer

Manuel Nolasco‑Quiroga, Marisol Rosas‑Díaz, José Moreno, Ricardo Godínez‑Aguilar, María José López‑Ibarra, Patricia Piña‑Sánchez, Isabel Alvarado‑Cabrero, Gerardo Vázquez‑Gómez, Leticia Rocha‑Zavaleta, Diego Arenas‑Aranda, Fabio Salamanca‑Gómez
Pages: 4779-4786
Published online on: 15 March 2019

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Article Open Access

Analysis of the role of DAMTC in lung adenocarcinoma cells based on the DNA microarrays

Binliang Wang, Yuanyuan Cai, Yiming Kong, Xiaobo Li, Haiwei Fu, Song Zhang, Tianwei Zhang
Pages: 4787-4794
Published online on: 15 March 2019

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Article Open Access

Alantolactone induces gastric cancer BGC‑823 cell apoptosis by regulating reactive oxygen species generation and the AKT signaling pathway

Xin Zhang, Hong‑Ming Zhang
Pages: 4795-4802
Published online on: 19 March 2019

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Article Open Access

Circular RNA ATXN7 is upregulated in non‑small cell lung cancer and promotes disease progression

Qi Huang, Shaodong Wang, Xiao Li, Fan Yang, Changjiang Feng, Kaize Zhong, Mantang Qiu, Jun Wang
Pages: 4803-4810
Published online on: 19 March 2019

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Article Open Access

CD151 confers metastatic potential to clear cell sarcoma of the soft tissue in animal model

Keisuke Kawashima, Chiemi Saigo, Yusuke Kito, Yuki Hanamatsu, Yuki Egawa, Tamotsu Takeuchi
Pages: 4811-4818
Published online on: 19 March 2019

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Article Open Access

MicroRNA‑9 enhances chemotherapy sensitivity of glioma to TMZ by suppressing TOPO II via the NF‑κB signaling pathway

Qingla Li, Yingnan Chang, Luyan Mu, Yuwen Song
Pages: 4819-4826
Published online on: 18 March 2019

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Article Open Access

Capsaicin induces apoptosis and autophagy in human melanoma cells

Haihan Chu, Meng Li, Xiuchun Wang
Pages: 4827-4834
Published online on: 03 April 2019

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Article Open Access

Talin2 regulates invasion of human breast cancer MDA‑MB‑231 cells via alteration of the tumor microenvironment

Zhengwei Wen, Yingfan Liang, Shengming Deng, Lilin Zou, Xiaofan Xie, Jifeng Yang, Yiwei Wu
Pages: 4835-4842
Published online on: 21 March 2019

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Article Open Access

Tumor growth under rhGM‑CSF application in an orthotopic rodent glioma model

Thomas Linsenmann, Anna Jawork, Thomas Westermaier, György Homola, Camelia Maria Monoranu, Giles Hamilton Vince, Almuth Friederike Kessler, Ralf‑Ingo Ernestus, Mario Löhr
Pages: 4843-4850
Published online on: 21 March 2019

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Article Open Access

Evaluation of the benefit of post‑mastectomy radiotherapy in patients with early‑stage breast cancer: A propensity score matching study

Wenjie Shi, Youhong Luo, Dongkang Zhao, Hao Huang, Weiyi Pang
Pages: 4851-4858
Published online on: 29 March 2019

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Article Open Access

Correlation of p16 and cyclin D1 expression with the incidence and prognosis of cardiac carcinoma

Haoxun Wang, Jing Wang, Bingbo Zhao
Pages: 4859-4864
Published online on: 26 March 2019

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Article Open Access

Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma

Jinpeng Jia, Pei Yin, Xingpeng Zhang, Fei Yang, Ge Song, Wenzhi Bi, Gang Han, Meng Xu, Wei Wang, Xiaoque Zheng
Pages: 4865-4870
Published online on: 13 March 2019

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Article Open Access

Expression of miRNA-146b-5p in patients with thyroid cancer in combination with Hashimoto's disease and its clinical significance

Ninglei Li, Xiaolong Liu, Luzhe Han, Rui Zhou, Jian Yan, Guoxiang Zhao, Lixin Liu
Pages: 4871-4876
Published online on: 20 March 2019

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Article Open Access

Increased CX3CL1 mRNA expression level is a positive prognostic factor in patients with lung adenocarcinoma

Jian Liu, Yan Li, Xiaoqin Zhu, Qing Li, Xiaohong Liang, Jun Xie, Song Hu, Wanda Peng, Chong Li
Pages: 4877-4890
Published online on: 03 April 2019

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Article Open Access

Impact of EMT in stage IIIB/IV NSCLC treated with erlotinib and bevacizumab when compared with cisplatin, gemcitabine and bevacizumab

Matthias Villalobos, Piotr Czapiewski, Niels Reinmuth, Jürgen R. Fischer, Stefan Andreas, Cornelius Kortsik, Monika Serke, Martin Wolf, Petra Neuser, Alexander Reuss, Philipp A. Schnabel, Michael Thomas
Pages: 4891-4900
Published online on: 15 March 2019

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Article Open Access

Study on value of ultrasonic elastography in diagnosis of clinical staging of cervical cancer and efficacy evaluation of radiotherapy

Yingying Zhang, Yuanyuan Yan, Yuejie Yang
Pages: 4901-4906
Published online on: 26 March 2019

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Article Open Access

KMT5A promotes metastasis of clear cell renal cell carcinoma through reducing cadherin‑1 expression

Zhen‑Zhong Lin, De‑Song Ming, Ya‑Bin Chen, Jian‑Ming Zhang, Hui‑Hua Chen, Jian‑Jia Jiang, Zhi‑Shan Zhang
Pages: 4907-4913
Published online on: 19 March 2019

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Article Open Access

NOTCH2/NOTCH3/DLL3/MAML1/ADAM17 signaling network is associated with ovarian cancer

Dongyu Jia, Jesse Underwood, Qiuping Xu, Qian Xie
Pages: 4914-4920
Published online on: 19 March 2019

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Article Open Access

Particle stability and structure on the peritoneal surface in pressurized intra‑peritoneal aerosol chemotherapy (PIPAC) analysed by electron microscopy: First evidence of a new physical concept for PIPAC

Tanja Khosrawipour, Justyna Schubert, Veria Khosrawipour, Haris Chaudhry, Jakub Grzesiak, Mohamed Arafkas, Agata Mikolajczyk
Pages: 4921-4927
Published online on: 19 March 2019

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Article Open Access

Long non‑coding RNA NEF inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells by inhibiting Wnt/β‑catenin signaling

Xiangyan Cui, Ning Fang, Yu Cui, Dong Xiao, Xin Wang
Pages: 4928-4934
Published online on: 15 March 2019

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Article Open Access

Overexpression of ZEB2‑AS1 lncRNA is associated with poor clinical outcomes in acute myeloid leukemia

Xiaolan Shi, Jiao Li, Liang Ma, Lijun Wen, Qinrong Wang, Hong Yao, Changgeng Ruan, Depei Wu, Xinyou Zhang, Suning Chen
Pages: 4935-4947
Published online on: 15 March 2019

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Article Open Access

High TNF‑α and/or p38MAPK expression predicts a favourable prognosis in patients with T1N0M0 hepatocellular carcinoma: An immunohistochemical study Corrigendum in /10.3892/ol.2019.10781

Mao Zhang, Jie Hu, Haoran Li, Shun Zhang, Weiyu Hu, Liqun Wu, Bing Han
Pages: 4948-4956
Published online on: 27 March 2019

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Article Open Access

HIT000218960 promotes gastric cancer cell proliferation and migration through upregulation of HMGA2 expression

Leitao Sun, Jieru Yu, Peipei Wang, Minhe Shen, Shanming Ruan
Pages: 4957-4963
Published online on: 21 March 2019

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Article Open Access

Effect of lincRNA-p21 targeting HIF-1α on biological functions of liver cancer cells

Yibiao Ye, Yaorong Peng, Yanshan Li, Chunxia Liu, Yunxiuxiu Xu, Wenbin Li
Pages: 4964-4968
Published online on: 28 March 2019

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Article Open Access

Long non‑coding RNA‑neighboring enhancer of FOXA2 inhibits the migration and invasion of small cell lung carcinoma cells by downregulating transforming growth factor‑β1

Lei Wu, Pan Wang
Pages: 4969-4975
Published online on: 15 March 2019

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Article Open Access

TP53BP2 decreases cell proliferation and induces autophagy in neuroblastoma cell lines

Yi Pang, Lianhong Pan, Yonghui Zhang, Guiyuan Liu
Pages: 4976-4984
Published online on: 15 March 2019

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Article Open Access

PAX3 is a biomarker and prognostic factor in melanoma: Database mining

Yong Liu, Shengnan Cui, Wenbin Li, Yiding Zhao, Xiaoning Yan, Jianqin Xu
Pages: 4985-4993
Published online on: 18 March 2019

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Article Open Access

RNA sequencing uncovers the key long non‑coding RNAs and potential molecular mechanism contributing to XAV939‑mediated inhibition of non‑small cell lung cancer

Haixiang Yu, Zhifeng Han, Zhenan Xu, Chong An, Lei Xu, Hua Xin
Pages: 4994-5004
Published online on: 27 March 2019

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Article Open Access

LINK‑A lncRNA functions in the metastasis of osteosarcoma by upregulating HIF1α

Boming Zhao, Kebin Liu, Lin Cai
Pages: 5005-5011
Published online on: 21 March 2019

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Article Open Access

Co‑inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo

Jiansong Wang, Huaijun Ji, Qiang Zhu, Xinshuang Yu, Juan Du, Zhongmin Jiang
Pages: 5012-5022
Published online on: 19 March 2019

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Article Open Access

The effects of BRCA1 expression on the chemosensitivity of gastric cancer cells to platinum agents

Geon Kim, Jisu Kim, Su‑Young Han, In Gyu Hwang, Hee Sung Kim, Hyeyoung Min
Pages: 5023-5029
Published online on: 19 March 2019

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Article Open Access

Ornithine transcarbamylase downregulation is associated with poor prognosis in hepatocellular carcinoma

Lin He, Xuefei Cai, Shengtao Cheng, Hongzhong Zhou, Zhenzhen Zhang, Jihua Ren, Fang Ren, Qiuxia Yang, Nana Tao, Juan Chen
Pages: 5030-5038
Published online on: 21 March 2019

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Article Open Access

Support of acute lymphoblastic leukemia cells by nonmalignant bone marrow stromal cells

Sana Usmani, Urmila Sivagnanalingam, Olena Tkachenko, Leti Nunez, Jessica C. Shand, Craig A. Mullen
Pages: 5039-5049
Published online on: 22 March 2019

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Article Open Access

Effect of gastrointestinal microbiome and its diversity on the expression of tumor‑infiltrating lymphocytes in breast cancer

Jiajie Shi, Cuizhi Geng, Meixiang Sang, Wei Gao, Sainan Li, Shan Yang, Zheng Li
Pages: 5050-5056
Published online on: 22 March 2019

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Article Open Access

Identification of a 13‑gene‑based classifier as a potential biomarker to predict the effects of fluorouracil‑based chemotherapy in colorectal cancer

Zuhuan Gan, Qiyuan Zou, Yan Lin, Zihai Xu, Zhong Huang, Zhichao Chen, Yufeng Lv
Pages: 5057-5063
Published online on: 19 March 2019

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Article Open Access

Selectively high efficacy of eribulin against high‑grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck

Yutaka Kobayashi, Hiroko Kitahara, Mariko Hirai, Akira Tanaka, Rei Jokaji, Kazuhiko Kobayashi, George Bou‑Gharios, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 5064-5072
Published online on: 19 March 2019

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Article Open Access

TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma

Youji Yan, Zhongjun Chen, Yixiang Liao, Jiajie Zhou
Pages: 5073-5079
Published online on: 19 March 2019

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Article Open Access

Overexpression of EPAC2 reduces the invasion of glioma cells via MMP‑2

Ming Jiang, Yan Zhuang, Wang‑Cun Zu, Lei Jiao, Seidu A. Richard, Shiming Zhang
Pages: 5080-5086
Published online on: 29 March 2019

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Article Open Access

miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Pages: 5087-5093
Published online on: 13 March 2019

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Article Open Access

Interleukin‑35 is associated with the tumorigenesis and progression of prostate cancer

Jialin Zhu, Xueling Yang, Yan Wang, Haonan Zhang, Zhi Guo
Pages: 5094-5102
Published online on: 03 April 2019

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Article Open Access

Effects of knockout of lincRNA‑p21 on the proliferation, migration and invasion ability of HepG2 liver cancer cells

Tongshan Wang, Jun Liu, Suihui Li, Zhengang Yuan, Xiangzhong Huang
Pages: 5103-5107
Published online on: 01 April 2019

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Article Open Access

miRNA-99a inhibits cell invasion and migration in liver cancer by directly targeting HOXA1

Changming Tao, Huiling Sun, Weiwei Sang, Shanshan Li
Pages: 5108-5114
Published online on: 29 March 2019

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Article Open Access

Expression and correlation of miR‑124 and miR‑126 in breast cancer

Fanfan Li
Pages: 5115-5119
Published online on: 22 March 2019

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Article Open Access

Effect of lncRNA ZEB1-AS1 on proliferation, invasion and apoptosis of glioma U87 cells

Wei Zhang, Lijun Xiong
Pages: 5120-5124
Published online on: 01 April 2019

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Article

Frequency and significance of epidermal growth factor receptor mutations detected by PCR methods in patients with non‑small cell lung cancer

Eiji Nakajima, Michio Sugita, Kinya Furukawa, Hidenobu Takahashi, Osamu Uchida, Youhei Kawaguchi, Tatsuo Ohira, Jun Matsubayashi, Norihiko Ikeda, Fred R. Hirsch, Wilbur A. Franklin
Pages: 5125-5131
Published online on: 18 March 2019

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Article Open Access

Radiosensitizing effect of 5‑aminolevulinic acid in colorectal cancer in vitro and in vivo

Kazuto Yamada, Yasutoshi Murayama, Yosuke Kamada, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Ryo Morimura, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Takeshi Kubota, Masayoshi Nakanishi, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji
Pages: 5132-5138
Published online on: 29 March 2019

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Article

Prognostic impact of interleukin‑6 and C‑reactive protein on patients with breast cancer

Tatsuo Shimura, Masahiko Shibata, Kenji Gonda, Yuko Murakami, Masaru Noda, Kazunoshin Tachibana, Noriko Abe, Tohru Ohtake
Pages: 5139-5146
Published online on: 21 March 2019

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Article

Differential expression of EphA5 protein in gastric carcinoma and its clinical significance

Wei Zhang, Xue Wei, Shuwei Guo, Jiandong Wang, Jing Liu, Hai Wang
Pages: 5147-5153
Published online on: 19 March 2019

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Article

Fluoroscopy‑guided long intestinal tube placement for the treatment of malignant bowel obstruction

Haiyang Lai, Ketong Wu, Yang Liu, Zhaofei Zeng, Bo Zhang
Pages: 5154-5158
Published online on: 15 March 2019

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Article

High expression of ubiquitin carboxyl‑terminal hydrolase 22 is associated with poor prognosis in hepatitis B virus‑associated liver cancer

Yong Liao, Xingsi Liang, Wenjin Liang, Zeming Li, Yan Wang, Lin Wang, Siqi Zhen, Bo Tang, Zhenran Wang
Pages: 5159-5168
Published online on: 15 March 2019

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Article

CRKII overexpression promotes the in vitro proliferation, migration and invasion potential of murine hepatocarcinoma Hca‑P cells

Zanmei Zhou, Xiuyan Sun, Chunmei Guo, Ming‑Zhong Sun, Shuqing Liu
Pages: 5169-5174
Published online on: 27 March 2019

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Article

Effect of the Nrf2‑ARE signaling pathway on biological characteristics and sensitivity to sunitinib in renal cell carcinoma

Shiliang Ji, Yufeng Xiong, Xingxing Zhao, Yanli Liu, Li Qiang Yu
Pages: 5175-5186
Published online on: 18 March 2019

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Article

Clinicopathological significance of TM4SF5 expression in human hepatocellular carcinoma tissues

Baojin Xu, Wu Lv, Xiaoyan Li, Lina Zhang, Jie Lin
Pages: 5187-5192
Published online on: 03 April 2019

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Article

MicroRNAs aid the assessment of programmed death ligand 1 expression in patients with non‑small cell lung cancer

Anna Grenda, Marcin Nicoś, Michał Szczyrek, Paweł Krawczyk, Tomasz Kucharczyk, Bożena Jarosz, Juliusz Pankowski, Marek Sawicki, Justyna Szumiło, Paulina Bukała, Janusz Milanowski
Pages: 5193-5200
Published online on: 03 April 2019

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Article

miR‑196a regulates the proliferation, invasion and migration of esophageal squamous carcinoma cells by targeting ANXA1

Changmei Hu, Jie Peng, Liang Lv, Xuehong Wang, Yuqian Zhou, Jirong Huo, Deliang Liu
Pages: 5201-5209
Published online on: 22 March 2019

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Article

Downregulation of miR‑136 promotes the progression of osteosarcoma and is associated with the prognosis of patients with osteosarcoma

Yanchen Chu, Xiaoli Hu, Guangfeng Wang, Zhijie Wang, Yanjin Wang
Pages: 5210-5218
Published online on: 01 April 2019

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Case Report

Transformation to small cell lung cancer and activation of KRAS during long‑term erlotinib maintenance in a patient with non‑small cell lung cancer: A case report

Yangchun Gu, Xiang Zhu, Baoshan Cao, Xue Wu, Xiaoling Tong, Yang W. Shao, Li Liang
Pages: 5219-5223
Published online on: 28 March 2019

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Article

In vitro effect of curcumin in combination with chemotherapy drugs in Ph+ acute lymphoblastic leukemia cells

Uriel Francisco Santana‑Bejarano, Lucina Bobadilla‑Morales, Lucero Mendoza‑Maldonado, Elizabeth Torres‑Anguiano, Sinhue Alejandro Brukman‑Jiménez, Cesar Cenobio Barba‑Barba, Jorge Román Corona‑Rivera, Alfredo Corona‑Rivera
Pages: 5224-5240
Published online on: 02 April 2019

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Article

High postoperative neutrophil‑to‑lymphocyte ratio as a poor prognostic marker in patients with upper tract urothelial carcinoma

Kiyoaki Nishihara, Shigetaka Suekane, Kousuke Ueda, Makoto Nakiri, Mitsunori Matsuo, Tsukasa Igawa
Pages: 5241-5250
Published online on: 21 March 2019

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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