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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2021 Volume 21 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Upregulation of phosphatidylinositol glycan anchor biosynthesis class C is associated with unfavorable survival prognosis in patients with hepatocellular carcinoma

Xiulan Peng, Changjiang Lei, Anbing He, Renfeng Luo, Yahong Cai, Weiguo Dong
Article Number: 237
Published online on: 26 January 2021

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Article Open Access

Lycorine hydrochloride induces reactive oxygen species‑mediated apoptosis via the mitochondrial apoptotic pathway and the JNK signaling pathway in the oral squamous cell carcinoma HSC‑3 cell line

Min-Hui Li, Xin Liao, Chen Li, Tian-Tian Wang, Yi-Song Sun, Kang Yang, Pei-Wen Jiang, Song-Ting Shi, Wen-Xin Zhang, Kun Zhang, Chao Li, Ping Yang
Article Number: 236
Published online on: 26 January 2021

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Article Open Access

MicroRNA‑9‑5p increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by downregulating high mobility group A2 expression

Huizhe Zheng, Bin Yan, Qi Wu, Jingli Zhang
Article Number: 235
Published online on: 26 January 2021

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Article Open Access

Expression and inhibitory effects of p53‑upregulated modulator of apoptosis in gallbladder carcinoma

Zhide Liu, Cheng Yan, Yangyan Xiao, Weichang Zhang, Li Wang, Qinglong Li, Wenwu Cai
Article Number: 234
Published online on: 26 January 2021

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Article

Chloroquine diphosphate suppresses liver cancer via inducing apoptosis in Wistar rats using interventional therapy

Xiaoguang Hao, Weijing Li
Article Number: 233
Published online on: 26 January 2021

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Article

Attenuating role of withaferin A in the proliferation and migration of lung cancer cells via a p53‑miR‑27a/miR‑10b pathway

Chen-Chu Lin, Tsung-Ying Yang, Hseuh-Ju Lu, Chen-Kai Wan, Shih-Lan Hsu, Chun-Chi Wu
Article Number: 232
Published online on: 26 January 2021

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Article Open Access

GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression Corrigendum in /10.3892/ol.2021.12836

Zhuoliang Zhang, Xingliang Fang, Guilin Xie, Jinlong Zhu
Article Number: 231
Published online on: 26 January 2021

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Article Open Access

Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation

Shuai Peng, Jincheng Wang, Chang Lu, Zelin Xu, Jing-Jing Chai, Qing Ke, Xin-Zhou Deng
Article Number: 230
Published online on: 26 January 2021

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Article Open Access

Association between microRNA‑527 and glypican‑3 in hepatocellular carcinoma

Kei Nomura, Akira Kitanaka, Hisakazu Iwama, Joji Tani, Takako Nomura, Mai Nakahara, Kyoko Ohura, Tomoko Tadokoro, Koji Fujita, Shima Mimura, Hirohito Yoneyama, Hideki Kobara, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Kunihiko Tsutsi, Takashi Himoto, Tsutomu Masaki
Article Number: 229
Published online on: 26 January 2021

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Correction Open Access

[Corrigendum] MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathway

Kai Wang, Shasha Yang, Yishen Gao, Caihong Zhang, Qiangbo Sui
Article Number: 228
Published online on: 26 January 2021

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Correction Open Access

[Corrigendum] Molecular heterogeneity of guanine nucleotide binding‑protein γ subunit 4 in left‑ and right‑sided colon cancer

Jintian Song, Jianwei Yang, Rongbo Lin, Xiongchao Cai, Liang Zheng, Yigui Chen
Article Number: 227
Published online on: 26 January 2021

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Article Open Access

p53 expression confers sensitivity to 5‑fluorouracil via distinct chromatin accessibility dynamics in human colorectal cancer

Chul Min Yang, Moo-Koo Kang, Woong-Jae Jung, Jung-Sik Joo, Yong-Jin Kim, Yeeun Choi, Hyoung-Pyo Kim
Article Number: 226
Published online on: 24 January 2021

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Article Open Access

Long non‑coding RNA MCM3AP‑AS1 facilitates colorectal cancer progression by regulating the microRNA‑599/ARPP19 axis

You Yu, Suhe Lai, Xiaochao Peng
Article Number: 225
Published online on: 24 January 2021

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Article Open Access

PALB2 upregulation is associated with a poor prognosis in pancreatic ductal adenocarcinoma

Ouyang Ge, Anle Huang, Xin Wang, Yuling Chen, Yuanchun Ye, Lutz Schomburg
Article Number: 224
Published online on: 24 January 2021

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Article Open Access

Differential expression of COL4A3 and collagen in upward and downward progressing types of nasopharyngeal carcinoma

Xiting Yang, Qiuji Wu, Fengyang Wu, Yahua Zhong
Article Number: 223
Published online on: 21 January 2021

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Article Open Access

Recombinant immunotoxin targeting GPC3 is cytotoxic to H466 small cell lung cancer cells

Ewelina Rodakowska, Aurelia Walczak‑Drzewiecka, Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Marcin Ratajewski, Michal Rozanski, Jaroslaw Dastych, Krzysztof Ginalski, Leszek Rychlewski
Article Number: 222
Published online on: 21 January 2021

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Article Open Access

Construction and validation of an N6‑methyladenosine‑associated prognostic signature in hepatocellular carcinoma

Peng Zhu, Qianqian Ren, Nan He, Cheng Zhou, Qianna Jin, Zhao Gong
Article Number: 221
Published online on: 21 January 2021

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Article Open Access

Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer

Yuhai Zhang, Yuling Hong, Dan Wang, Linshan Duan, Yanling Liu, Long Li, Di Liu, Kunbin Zhuang, Chaoxin Wei, Guogeng Zheng, Chunyong Huo, Guoyan Liu
Article Number: 220
Published online on: 21 January 2021

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Retraction Open Access

[Retracted] Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway

Dongjie Ma, Shanqing Li, Yushang Cui, Li Li, Hongsheng Liu, Yeye Chen, Xiaoyun Zhou
Article Number: 219
Published online on: 21 January 2021

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Article Open Access

A modified prognostic model in patients with diffuse large B‑cell lymphoma treated with immunochemotherapy

Peiqi Zhao, Lei Zhu, Lanfang Li, Shiyong Zhou, Lihua Qiu, Zhengzi Qian, Wengui Xu, Huilai Zhang
Article Number: 218
Published online on: 20 January 2021

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Article Open Access

Hypoxia increases the expression of stem cell markers in human osteosarcoma cells

Jinluan Lin, Xinwu Wang, Xinwen Wang, Shenglin Wang, Rongkai Shen, Yanbing Yang, Jianyong Xu, Jianhua Lin
Article Number: 217
Published online on: 20 January 2021

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Correction Open Access

[Corrigendum] Antitumor activity of gambogic acid on NCI‑H1993 xenografts via MET signaling pathway downregulation

Donglei Li, Huiwei Yang, Runpu Li, Yanli Wang, Weijun Wang, Dongjie Li, Shaolin Ma, Xuyu Zhang
Article Number: 216
Published online on: 20 January 2021

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Article Open Access

Growth factors contribute to the mediation of angiogenic capacity of glioma‑associated mesenchymal stem cells

Qing Zhang, Wei Xiang, Bing-Zhou Xue, Dong-Ye Yi, Hong-Yang Zhao, Peng Fu
Article Number: 215
Published online on: 19 January 2021

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Article Open Access

Association between estrogen receptor β polymorphisms and prostate cancer in a Slovak population

Jana Jurečeková, Monika Kmeťová Sivoňová, Henrieta Drobková, Márk Híveš, Daniel Evin, Ján Kliment, Dušan Dobrota
Article Number: 214
Published online on: 19 January 2021

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Article Open Access

Chemopreventive effect of 4'‑hydroxychalcone on intestinal tumorigenesis in ApcMin mice Corrigendum in /10.3892/ol.2021.12741

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge
Article Number: 213
Published online on: 18 January 2021

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Article Open Access

Immunological status of peripheral blood is associated with prognosis in patients with bone and soft-tissue sarcoma

Youngji Kim, Eisuke Kobayashi, Yoshiyuki Suehara, Ayumu Ito, Daisuke Kubota, Yoshikazu Tanzawa, Makoto Endo, Fumihiko Nakatani, Tetsuya Nakatsura, Akira Kawai, Kazuo Kaneko, Shigehisa Kitano
Article Number: 212
Published online on: 18 January 2021

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Article Open Access

MCM3AP‑AS1 promotes cisplatin resistance in gastric cancer cells via the miR‑138/FOXC1 axis

Han Sun, Ping Wu, Bao Zhang, Xia Wu, Weixu Chen
Article Number: 211
Published online on: 18 January 2021

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Article Open Access

Downregulation of long non‑coding RNA LINC‑PINT serves as a diagnostic and prognostic biomarker in patients with non‑small cell lung cancer

Chunjie Zhang, Cuixue Gong, Jianzhao Li, Jiaying Tang
Article Number: 210
Published online on: 18 January 2021

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Article

Identification of AKT1/β-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment

Gozde Hasbal‑Celikok, Pinar Aksoy‑Sagirli, Gulsum Altiparmak‑Ulbegi, Ayse Can
Article Number: 209
Published online on: 14 January 2021

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Article Open Access

Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 208
Published online on: 14 January 2021

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Article Open Access

In vivo evaluation of percutaneous carbon dioxide treatment for improving intratumoral hypoxia using 18F-fluoromisonidazole PET-CT

Koji Maruyama, Takuya Okada, Takeshi Ueha, Kayako Isohashi, Hayato Ikeda, Yasukazu Kanai, Koji Sasaki, Tomoyuki Gentsu, Eisuke Ueshima, Keitaro Sofue, Munenobu Nogami, Masato Yamaguchi, Koji Sugimoto, Yoshitada Sakai, Jun Hatazawa, Takamichi Murakami
Article Number: 207
Published online on: 14 January 2021

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Article Open Access

Optimization of 7,12‑dimethylbenz(a)anthracene‑induced rat epithelial ovarian tumors

Xiu Ying Yang, Ying Li, Song Qi Cai, Li Wang, Jin Wei Qiang
Article Number: 206
Published online on: 14 January 2021

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Article Open Access

Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker

Xiao-Cong Mo, Zi-Tong Zhang, Meng-Jia Song, Zi-Qi Zhou, Jian-Xiong Zeng, Yu-Fei Du, Feng-Ze Sun, Jie-Ying Yang, Jun-Yi He, Yue Huang, Jian-Chuan Xia, De-Sheng Weng
Article Number: 205
Published online on: 14 January 2021

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Article Open Access

Gene expression profiling of CD34(+) cells from patients with myeloproliferative neoplasms

Mugdha Sharma, Chandra Bhavani, Srinag Bangalore Suresh, John Paul, Lokendra Yadav, Cecil Ross, Sweta Srivastava
Article Number: 204
Published online on: 12 January 2021

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Article Open Access

Tumor β‑catenin expression is associated with immune evasion in non‑small cell lung cancer with high tumor mutation burden

Satoshi Muto, Yuki Ozaki, Hikaru Yamaguchi, Hayato Mine, Hironori Takagi, Masayuki Watanabe, Takuya Inoue, Takumi Yamaura, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hideaki Nanamiya, Jun-Ichi Imai, Takao Isogai, Shinya Watanabe, Hiroyuki Suzuki
Article Number: 203
Published online on: 12 January 2021

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Article

A novel Tn antigen epitope‑recognizing antibody for MUC1 predicts clinical outcome in patients with primary lung adenocarcinoma

Tatsuya Kato, Hideki Ujiie, Kanako C. Hatanaka, Ayae Nange, Asami Okumura, Kaho Tsubame, Kentato Naruchi, Masaharu Sato, Kichizo Kaga, Yoshihiro Matsuno, Satoru Wakasa, Yutaka Hatanaka
Article Number: 202
Published online on: 12 January 2021

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Article

HDAC6-selective inhibitors enhance anticancer effects of paclitaxel in ovarian cancer cells

Jung Yoo, Yu Hyun Jeon, Dong Hoon Lee, Go Woon Kim, Sang Wu Lee, So Yeon Kim, Jongsun Park, So Hee Kwon
Article Number: 201
Published online on: 12 January 2021

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Article Open Access

MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 200
Published online on: 12 January 2021

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Correction Open Access

[Corrigendum] MicroRNA‑26b suppresses autophagy in breast cancer cells by targeting DRAM1 mRNA, and is downregulated by irradiation

Cuida Meng, Yang Liu, Yannan Shen, Shuchun Liu, Zhicheng Wang, Qingsheng Ye, Hongyang Liu, Xiaodong Liu, Lili Jia
Article Number: 199
Published online on: 12 January 2021

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Correction Open Access

[Corrigendum] Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9‑likevia LIN9

Huai Mei Chen, Jia Wang, Ying Feng Zhang, Yan Hong Gao
Article Number: 198
Published online on: 12 January 2021

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Article Open Access

Blocking the short isoform of augmenter of liver regeneration inhibits proliferation of human multiple myeloma U266 cells via the MAPK/STAT3/cell cycle signaling pathway

Wenqi Huang, Hang Sun, Ting Hu, Dongju Zhu, Xianli Long, Hui Guo, Qi Liu
Article Number: 197
Published online on: 12 January 2021

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Article Open Access

Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL

Xunlei Pang, Yanhong Wang, Bei Miao, Sujuan Fei, Weichang Chen
Article Number: 196
Published online on: 11 January 2021

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Correction Open Access

[Corrigendum] β‑Hydroxyisovaleryl‑shikonin induces human cervical cancer cell apoptosis via PI3K/AKT/mTOR signaling

Dan Lu, Jing Qian, Wei Li, Qianqian Feng, Shu Pan, Siquan Zhang
Article Number: 195
Published online on: 08 January 2021

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Article Open Access

Key genes in youth colorectal cancer based on data mining and verification by reverse transcription‑quantitative PCR

Jianxin Chen, Min Lin, Yan Che, Jian Guo, Wei Lin
Article Number: 194
Published online on: 08 January 2021

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Article Open Access

Long non-coding RNA OTUD6B-AS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells via downregulation of microRNA-3171

Wei Wang, Xia Cheng, Jianhua Zhu
Article Number: 193
Published online on: 08 January 2021

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Article Open Access

Luteolin inhibits proliferation, triggers apoptosis and modulates Akt/mTOR and MAP kinase pathways in HeLa cells

Ritu Raina, Sreepoorna Pramodh, Naushad Rais, Shafiul Haque, Jasmin Shafarin, Khuloud Bajbouj, Mawieh Hamad, Arif Hussain
Article Number: 192
Published online on: 07 January 2021

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Article

CD90 affects the biological behavior and energy metabolism level of gastric cancer cells by targeting the PI3K/AKT/HIF‑1α signaling pathway

Lu Gao, Jun Li, Junyu He, Lin Liang, Zhengxi He, Chunxue Yue, Xi Jin, Gengqiu Luo, Yanhong Zhou
Article Number: 191
Published online on: 07 January 2021

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Correction Open Access

[Corrigendum] Primary sternum diffuse large B‑cell lymphoma: A case report and a review of the literature

Meng-Ying Tong, Xian Zhang, Zhe Yu, Xiu-Hua Sun, Shuang Li, Yang Zhang
Article Number: 190
Published online on: 07 January 2021

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Article Open Access

Bioinformatics and immunohistochemistry analyses of expression levels and clinical significance of CXCL2 and TANs in an oral squamous cell carcinoma tumor microenvironment of Prophyromonas gingivalis infection

Zhi-Chen Guo, Sakendeke Jumatai, Si-Li Jing, Lu-Lu Hu, Xin-Yu Jia, Zhong-Cheng Gong
Article Number: 189
Published online on: 06 January 2021

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Article Open Access

Comprehensive evaluation of risk factors for lymph node metastasis in patients with papillary thyroid carcinoma

Yan Dong, Dan Wang, Yisheng Luo, Ling Chen, Huili Bai, Yifan Shen, Yangli Zhang, Xueping Chen, Xinliang Su, Jinqiu Zhao, Huandong Liu, Jungao Lu, Zuoyi Yao, Yajing Zhao, Changlong He, Xiaosong Li
Article Number: 188
Published online on: 06 January 2021

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Article Open Access

Akt regulates RSK2 to alter phosphorylation level of H2A.X in breast cancer

Zhi-Feng Guo, Fan-Long Kong
Article Number: 187
Published online on: 06 January 2021

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Article Open Access

Curcumin suppresses colorectal tumorigenesis via the Wnt/β‑catenin signaling pathway by downregulating Axin2

Jiaxue Hao, Xufen Dai, Juan Gao, Yuexuan Li, Zhaoling Hou, Zhongman Chang, Yuxin Wang
Article Number: 186
Published online on: 06 January 2021

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Article Open Access

A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high‑grade serous ovarian carcinoma

Kristýna Němejcová, Michaela Bártů, Jan Hojný, Nikola Hájková, Romana Michálková, Eva Krkavcová, Ivana Stružinská, Hiep Quang Bui, Pavel Dundr, David Cibula, Kateřina Jirsová
Article Number: 185
Published online on: 06 January 2021

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Article Open Access

Expression of Twist, Slug and Snail in esophageal squamous cell carcinoma and their prognostic significance

Shanshan Xu, Yaxing Zhou, Hadeti Biekemitoufu, Hui Wang, Chao Li, Wenjing Zhang, Yuqing Ma
Article Number: 184
Published online on: 06 January 2021

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Article Open Access

MicroRNA‑367‑3p induces apoptosis and suppresses migration of MCF‑7 cells by downregulating the expression of human choline kinase α

Sweta Raikundalia, Siti Aisyah Faten Mohamed Sa'dom, Ling Ling Few, Wei Cun See Too
Article Number: 183
Published online on: 06 January 2021

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Article Open Access

Clinicopathological characteristics of extranodal follicular dendritic cell sarcoma: A report of two cases

Xing Zhao, Dayong Sun, Gang Zhang
Article Number: 182
Published online on: 06 January 2021

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Article Open Access

Sarcoma‑180 tumor affects the quality of oocytes in mice

Zihang Chen, Simin Wang, Xuexia Luo, Yanhong Yang
Article Number: 181
Published online on: 06 January 2021

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Article Open Access

Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma

Bingsheng Yang, Zexin Su, Guoli Chen, Zhirui Zeng, Jianye Tan, Guofeng Wu, Shuang Zhu, Lijun Lin
Article Number: 180
Published online on: 06 January 2021

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Article

Targeted exome sequencing for the identification of common mutational signatures and potential driver mutations
for brain metastases and prognosis

Dainan Zhang, Xi Wang, Shunchang Ma, Peiliang Li, Fei Xue, Beibei Mao, Xiudong Guan, Wenjianlong Zhou, Jiayi Peng, Kun Su, Chuanbao Zhang, Wang Jia
Article Number: 179
Published online on: 06 January 2021

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Successful treatment of two relapsed patients with t(11;19)(q23;p13) acute myeloid leukemia by CLAE chemotherapy sequential with allogeneic hematopoietic stem cell transplantation: Case reports

Shandong Tao, Lixiao Song, Yuan Deng, Yue Chen, Yimin Gan, Yunjie Li, Yihan Ding, Zhe Zhang, Banghe Ding, Zhengmei He, Chunling Wang, Liang Yu
Article Number: 178
Published online on: 06 January 2021

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Phosphorylation of PED/PEA‑15 at Ser116 and phosphorylation of p27 at Thr187 indicates a poor prognosis in hepatocellular carcinoma

Yifeng Wu, Xianpeng Li, Mingliang Chen, Zhikun Liu, Xuanyu Zhang, Shusen Zheng, Xiao Xu
Article Number: 177
Published online on: 06 January 2021

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Phosphorylated form of pyruvate dehydrogenase α1 mediates tumor necrosis factor α‑induced glioma cell migration

Zijun Yang, Yidan Wang, Li Zhang, Chenjin Zhao, Donglin Wang
Article Number: 176
Published online on: 06 January 2021

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Correction Open Access

[Corrigendum] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 175
Published online on: 05 January 2021

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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