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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2021 Volume 21 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Upregulation of phosphatidylinositol glycan anchor biosynthesis class C is associated with unfavorable survival prognosis in patients with hepatocellular carcinoma

Xiulan Peng, Changjiang Lei, Anbing He, Renfeng Luo, Yahong Cai, Weiguo Dong
Article Number: 237
Published online on: 26 January 2021

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Article Open Access

Lycorine hydrochloride induces reactive oxygen species‑mediated apoptosis via the mitochondrial apoptotic pathway and the JNK signaling pathway in the oral squamous cell carcinoma HSC‑3 cell line

Min-Hui Li, Xin Liao, Chen Li, Tian-Tian Wang, Yi-Song Sun, Kang Yang, Pei-Wen Jiang, Song-Ting Shi, Wen-Xin Zhang, Kun Zhang, Chao Li, Ping Yang
Article Number: 236
Published online on: 26 January 2021

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Article Open Access

MicroRNA‑9‑5p increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by downregulating high mobility group A2 expression

Huizhe Zheng, Bin Yan, Qi Wu, Jingli Zhang
Article Number: 235
Published online on: 26 January 2021

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Article Open Access

Expression and inhibitory effects of p53‑upregulated modulator of apoptosis in gallbladder carcinoma

Zhide Liu, Cheng Yan, Yangyan Xiao, Weichang Zhang, Li Wang, Qinglong Li, Wenwu Cai
Article Number: 234
Published online on: 26 January 2021

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Article

Chloroquine diphosphate suppresses liver cancer via inducing apoptosis in Wistar rats using interventional therapy

Xiaoguang Hao, Weijing Li
Article Number: 233
Published online on: 26 January 2021

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Article

Attenuating role of withaferin A in the proliferation and migration of lung cancer cells via a p53‑miR‑27a/miR‑10b pathway

Chen-Chu Lin, Tsung-Ying Yang, Hseuh-Ju Lu, Chen-Kai Wan, Shih-Lan Hsu, Chun-Chi Wu
Article Number: 232
Published online on: 26 January 2021

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Article Open Access

GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression Corrigendum in /10.3892/ol.2021.12836

Zhuoliang Zhang, Xingliang Fang, Guilin Xie, Jinlong Zhu
Article Number: 231
Published online on: 26 January 2021

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Article Open Access

Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation

Shuai Peng, Jincheng Wang, Chang Lu, Zelin Xu, Jing-Jing Chai, Qing Ke, Xin-Zhou Deng
Article Number: 230
Published online on: 26 January 2021

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Article Open Access

Association between microRNA‑527 and glypican‑3 in hepatocellular carcinoma

Kei Nomura, Akira Kitanaka, Hisakazu Iwama, Joji Tani, Takako Nomura, Mai Nakahara, Kyoko Ohura, Tomoko Tadokoro, Koji Fujita, Shima Mimura, Hirohito Yoneyama, Hideki Kobara, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Kunihiko Tsutsi, Takashi Himoto, Tsutomu Masaki
Article Number: 229
Published online on: 26 January 2021

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Correction Open Access

[Corrigendum] MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathway

Kai Wang, Shasha Yang, Yishen Gao, Caihong Zhang, Qiangbo Sui
Article Number: 228
Published online on: 26 January 2021

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Correction Open Access

[Corrigendum] Molecular heterogeneity of guanine nucleotide binding‑protein γ subunit 4 in left‑ and right‑sided colon cancer

Jintian Song, Jianwei Yang, Rongbo Lin, Xiongchao Cai, Liang Zheng, Yigui Chen
Article Number: 227
Published online on: 26 January 2021

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Article Open Access

p53 expression confers sensitivity to 5‑fluorouracil via distinct chromatin accessibility dynamics in human colorectal cancer

Chul Min Yang, Moo-Koo Kang, Woong-Jae Jung, Jung-Sik Joo, Yong-Jin Kim, Yeeun Choi, Hyoung-Pyo Kim
Article Number: 226
Published online on: 24 January 2021

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Article Open Access

Long non‑coding RNA MCM3AP‑AS1 facilitates colorectal cancer progression by regulating the microRNA‑599/ARPP19 axis

You Yu, Suhe Lai, Xiaochao Peng
Article Number: 225
Published online on: 24 January 2021

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Article Open Access

PALB2 upregulation is associated with a poor prognosis in pancreatic ductal adenocarcinoma

Ouyang Ge, Anle Huang, Xin Wang, Yuling Chen, Yuanchun Ye, Lutz Schomburg
Article Number: 224
Published online on: 24 January 2021

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Article Open Access

Differential expression of COL4A3 and collagen in upward and downward progressing types of nasopharyngeal carcinoma

Xiting Yang, Qiuji Wu, Fengyang Wu, Yahua Zhong
Article Number: 223
Published online on: 21 January 2021

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Article Open Access

Recombinant immunotoxin targeting GPC3 is cytotoxic to H466 small cell lung cancer cells

Ewelina Rodakowska, Aurelia Walczak‑Drzewiecka, Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Marcin Ratajewski, Michal Rozanski, Jaroslaw Dastych, Krzysztof Ginalski, Leszek Rychlewski
Article Number: 222
Published online on: 21 January 2021

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Article Open Access

Construction and validation of an N6‑methyladenosine‑associated prognostic signature in hepatocellular carcinoma

Peng Zhu, Qianqian Ren, Nan He, Cheng Zhou, Qianna Jin, Zhao Gong
Article Number: 221
Published online on: 21 January 2021

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Article Open Access

Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer

Yuhai Zhang, Yuling Hong, Dan Wang, Linshan Duan, Yanling Liu, Long Li, Di Liu, Kunbin Zhuang, Chaoxin Wei, Guogeng Zheng, Chunyong Huo, Guoyan Liu
Article Number: 220
Published online on: 21 January 2021

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Retraction Open Access

[Retracted] Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway

Dongjie Ma, Shanqing Li, Yushang Cui, Li Li, Hongsheng Liu, Yeye Chen, Xiaoyun Zhou
Article Number: 219
Published online on: 21 January 2021

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Article Open Access

A modified prognostic model in patients with diffuse large B‑cell lymphoma treated with immunochemotherapy

Peiqi Zhao, Lei Zhu, Lanfang Li, Shiyong Zhou, Lihua Qiu, Zhengzi Qian, Wengui Xu, Huilai Zhang
Article Number: 218
Published online on: 20 January 2021

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Article Open Access

Hypoxia increases the expression of stem cell markers in human osteosarcoma cells

Jinluan Lin, Xinwu Wang, Xinwen Wang, Shenglin Wang, Rongkai Shen, Yanbing Yang, Jianyong Xu, Jianhua Lin
Article Number: 217
Published online on: 20 January 2021

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Correction Open Access

[Corrigendum] Antitumor activity of gambogic acid on NCI‑H1993 xenografts via MET signaling pathway downregulation

Donglei Li, Huiwei Yang, Runpu Li, Yanli Wang, Weijun Wang, Dongjie Li, Shaolin Ma, Xuyu Zhang
Article Number: 216
Published online on: 20 January 2021

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Article Open Access

Growth factors contribute to the mediation of angiogenic capacity of glioma‑associated mesenchymal stem cells

Qing Zhang, Wei Xiang, Bing-Zhou Xue, Dong-Ye Yi, Hong-Yang Zhao, Peng Fu
Article Number: 215
Published online on: 19 January 2021

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Article Open Access

Association between estrogen receptor β polymorphisms and prostate cancer in a Slovak population

Jana Jurečeková, Monika Kmeťová Sivoňová, Henrieta Drobková, Márk Híveš, Daniel Evin, Ján Kliment, Dušan Dobrota
Article Number: 214
Published online on: 19 January 2021

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Article Open Access

Chemopreventive effect of 4'‑hydroxychalcone on intestinal tumorigenesis in ApcMin mice Corrigendum in /10.3892/ol.2021.12741

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge
Article Number: 213
Published online on: 18 January 2021

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Article Open Access

Immunological status of peripheral blood is associated with prognosis in patients with bone and soft-tissue sarcoma

Youngji Kim, Eisuke Kobayashi, Yoshiyuki Suehara, Ayumu Ito, Daisuke Kubota, Yoshikazu Tanzawa, Makoto Endo, Fumihiko Nakatani, Tetsuya Nakatsura, Akira Kawai, Kazuo Kaneko, Shigehisa Kitano
Article Number: 212
Published online on: 18 January 2021

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Article Open Access

MCM3AP‑AS1 promotes cisplatin resistance in gastric cancer cells via the miR‑138/FOXC1 axis

Han Sun, Ping Wu, Bao Zhang, Xia Wu, Weixu Chen
Article Number: 211
Published online on: 18 January 2021

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Article Open Access

Downregulation of long non‑coding RNA LINC‑PINT serves as a diagnostic and prognostic biomarker in patients with non‑small cell lung cancer

Chunjie Zhang, Cuixue Gong, Jianzhao Li, Jiaying Tang
Article Number: 210
Published online on: 18 January 2021

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Article

Identification of AKT1/β-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment

Gozde Hasbal‑Celikok, Pinar Aksoy‑Sagirli, Gulsum Altiparmak‑Ulbegi, Ayse Can
Article Number: 209
Published online on: 14 January 2021

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Article Open Access

Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 208
Published online on: 14 January 2021

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Article Open Access

In vivo evaluation of percutaneous carbon dioxide treatment for improving intratumoral hypoxia using 18F-fluoromisonidazole PET-CT

Koji Maruyama, Takuya Okada, Takeshi Ueha, Kayako Isohashi, Hayato Ikeda, Yasukazu Kanai, Koji Sasaki, Tomoyuki Gentsu, Eisuke Ueshima, Keitaro Sofue, Munenobu Nogami, Masato Yamaguchi, Koji Sugimoto, Yoshitada Sakai, Jun Hatazawa, Takamichi Murakami
Article Number: 207
Published online on: 14 January 2021

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Article Open Access

Optimization of 7,12‑dimethylbenz(a)anthracene‑induced rat epithelial ovarian tumors

Xiu Ying Yang, Ying Li, Song Qi Cai, Li Wang, Jin Wei Qiang
Article Number: 206
Published online on: 14 January 2021

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Article Open Access

Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker

Xiao-Cong Mo, Zi-Tong Zhang, Meng-Jia Song, Zi-Qi Zhou, Jian-Xiong Zeng, Yu-Fei Du, Feng-Ze Sun, Jie-Ying Yang, Jun-Yi He, Yue Huang, Jian-Chuan Xia, De-Sheng Weng
Article Number: 205
Published online on: 14 January 2021

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Article Open Access

Gene expression profiling of CD34(+) cells from patients with myeloproliferative neoplasms

Mugdha Sharma, Chandra Bhavani, Srinag Bangalore Suresh, John Paul, Lokendra Yadav, Cecil Ross, Sweta Srivastava
Article Number: 204
Published online on: 12 January 2021

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Article Open Access

Tumor β‑catenin expression is associated with immune evasion in non‑small cell lung cancer with high tumor mutation burden

Satoshi Muto, Yuki Ozaki, Hikaru Yamaguchi, Hayato Mine, Hironori Takagi, Masayuki Watanabe, Takuya Inoue, Takumi Yamaura, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hideaki Nanamiya, Jun-Ichi Imai, Takao Isogai, Shinya Watanabe, Hiroyuki Suzuki
Article Number: 203
Published online on: 12 January 2021

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Article

A novel Tn antigen epitope‑recognizing antibody for MUC1 predicts clinical outcome in patients with primary lung adenocarcinoma

Tatsuya Kato, Hideki Ujiie, Kanako C. Hatanaka, Ayae Nange, Asami Okumura, Kaho Tsubame, Kentato Naruchi, Masaharu Sato, Kichizo Kaga, Yoshihiro Matsuno, Satoru Wakasa, Yutaka Hatanaka
Article Number: 202
Published online on: 12 January 2021

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Article

HDAC6-selective inhibitors enhance anticancer effects of paclitaxel in ovarian cancer cells

Jung Yoo, Yu Hyun Jeon, Dong Hoon Lee, Go Woon Kim, Sang Wu Lee, So Yeon Kim, Jongsun Park, So Hee Kwon
Article Number: 201
Published online on: 12 January 2021

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Article Open Access

MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 200
Published online on: 12 January 2021

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Correction Open Access

[Corrigendum] MicroRNA‑26b suppresses autophagy in breast cancer cells by targeting DRAM1 mRNA, and is downregulated by irradiation

Cuida Meng, Yang Liu, Yannan Shen, Shuchun Liu, Zhicheng Wang, Qingsheng Ye, Hongyang Liu, Xiaodong Liu, Lili Jia
Article Number: 199
Published online on: 12 January 2021

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Correction Open Access

[Corrigendum] Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9‑likevia LIN9

Huai Mei Chen, Jia Wang, Ying Feng Zhang, Yan Hong Gao
Article Number: 198
Published online on: 12 January 2021

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Article Open Access

Blocking the short isoform of augmenter of liver regeneration inhibits proliferation of human multiple myeloma U266 cells via the MAPK/STAT3/cell cycle signaling pathway

Wenqi Huang, Hang Sun, Ting Hu, Dongju Zhu, Xianli Long, Hui Guo, Qi Liu
Article Number: 197
Published online on: 12 January 2021

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Article Open Access

Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL

Xunlei Pang, Yanhong Wang, Bei Miao, Sujuan Fei, Weichang Chen
Article Number: 196
Published online on: 11 January 2021

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Correction Open Access

[Corrigendum] β‑Hydroxyisovaleryl‑shikonin induces human cervical cancer cell apoptosis via PI3K/AKT/mTOR signaling

Dan Lu, Jing Qian, Wei Li, Qianqian Feng, Shu Pan, Siquan Zhang
Article Number: 195
Published online on: 08 January 2021

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Article Open Access

Key genes in youth colorectal cancer based on data mining and verification by reverse transcription‑quantitative PCR

Jianxin Chen, Min Lin, Yan Che, Jian Guo, Wei Lin
Article Number: 194
Published online on: 08 January 2021

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Article Open Access

Long non-coding RNA OTUD6B-AS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells via downregulation of microRNA-3171

Wei Wang, Xia Cheng, Jianhua Zhu
Article Number: 193
Published online on: 08 January 2021

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Article Open Access

Luteolin inhibits proliferation, triggers apoptosis and modulates Akt/mTOR and MAP kinase pathways in HeLa cells

Ritu Raina, Sreepoorna Pramodh, Naushad Rais, Shafiul Haque, Jasmin Shafarin, Khuloud Bajbouj, Mawieh Hamad, Arif Hussain
Article Number: 192
Published online on: 07 January 2021

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Article

CD90 affects the biological behavior and energy metabolism level of gastric cancer cells by targeting the PI3K/AKT/HIF‑1α signaling pathway

Lu Gao, Jun Li, Junyu He, Lin Liang, Zhengxi He, Chunxue Yue, Xi Jin, Gengqiu Luo, Yanhong Zhou
Article Number: 191
Published online on: 07 January 2021

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Correction Open Access

[Corrigendum] Primary sternum diffuse large B‑cell lymphoma: A case report and a review of the literature

Meng-Ying Tong, Xian Zhang, Zhe Yu, Xiu-Hua Sun, Shuang Li, Yang Zhang
Article Number: 190
Published online on: 07 January 2021

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Article Open Access

Bioinformatics and immunohistochemistry analyses of expression levels and clinical significance of CXCL2 and TANs in an oral squamous cell carcinoma tumor microenvironment of Prophyromonas gingivalis infection

Zhi-Chen Guo, Sakendeke Jumatai, Si-Li Jing, Lu-Lu Hu, Xin-Yu Jia, Zhong-Cheng Gong
Article Number: 189
Published online on: 06 January 2021

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Article Open Access

Comprehensive evaluation of risk factors for lymph node metastasis in patients with papillary thyroid carcinoma

Yan Dong, Dan Wang, Yisheng Luo, Ling Chen, Huili Bai, Yifan Shen, Yangli Zhang, Xueping Chen, Xinliang Su, Jinqiu Zhao, Huandong Liu, Jungao Lu, Zuoyi Yao, Yajing Zhao, Changlong He, Xiaosong Li
Article Number: 188
Published online on: 06 January 2021

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Article Open Access

Akt regulates RSK2 to alter phosphorylation level of H2A.X in breast cancer

Zhi-Feng Guo, Fan-Long Kong
Article Number: 187
Published online on: 06 January 2021

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Article Open Access

Curcumin suppresses colorectal tumorigenesis via the Wnt/β‑catenin signaling pathway by downregulating Axin2

Jiaxue Hao, Xufen Dai, Juan Gao, Yuexuan Li, Zhaoling Hou, Zhongman Chang, Yuxin Wang
Article Number: 186
Published online on: 06 January 2021

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Article Open Access

A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high‑grade serous ovarian carcinoma

Kristýna Němejcová, Michaela Bártů, Jan Hojný, Nikola Hájková, Romana Michálková, Eva Krkavcová, Ivana Stružinská, Hiep Quang Bui, Pavel Dundr, David Cibula, Kateřina Jirsová
Article Number: 185
Published online on: 06 January 2021

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Article Open Access

Expression of Twist, Slug and Snail in esophageal squamous cell carcinoma and their prognostic significance

Shanshan Xu, Yaxing Zhou, Hadeti Biekemitoufu, Hui Wang, Chao Li, Wenjing Zhang, Yuqing Ma
Article Number: 184
Published online on: 06 January 2021

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Article Open Access

MicroRNA‑367‑3p induces apoptosis and suppresses migration of MCF‑7 cells by downregulating the expression of human choline kinase α

Sweta Raikundalia, Siti Aisyah Faten Mohamed Sa'dom, Ling Ling Few, Wei Cun See Too
Article Number: 183
Published online on: 06 January 2021

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Article Open Access

Clinicopathological characteristics of extranodal follicular dendritic cell sarcoma: A report of two cases

Xing Zhao, Dayong Sun, Gang Zhang
Article Number: 182
Published online on: 06 January 2021

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Article Open Access

Sarcoma‑180 tumor affects the quality of oocytes in mice

Zihang Chen, Simin Wang, Xuexia Luo, Yanhong Yang
Article Number: 181
Published online on: 06 January 2021

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Article Open Access

Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma

Bingsheng Yang, Zexin Su, Guoli Chen, Zhirui Zeng, Jianye Tan, Guofeng Wu, Shuang Zhu, Lijun Lin
Article Number: 180
Published online on: 06 January 2021

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Targeted exome sequencing for the identification of common mutational signatures and potential driver mutations
for brain metastases and prognosis

Dainan Zhang, Xi Wang, Shunchang Ma, Peiliang Li, Fei Xue, Beibei Mao, Xiudong Guan, Wenjianlong Zhou, Jiayi Peng, Kun Su, Chuanbao Zhang, Wang Jia
Article Number: 179
Published online on: 06 January 2021

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Successful treatment of two relapsed patients with t(11;19)(q23;p13) acute myeloid leukemia by CLAE chemotherapy sequential with allogeneic hematopoietic stem cell transplantation: Case reports

Shandong Tao, Lixiao Song, Yuan Deng, Yue Chen, Yimin Gan, Yunjie Li, Yihan Ding, Zhe Zhang, Banghe Ding, Zhengmei He, Chunling Wang, Liang Yu
Article Number: 178
Published online on: 06 January 2021

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Phosphorylation of PED/PEA‑15 at Ser116 and phosphorylation of p27 at Thr187 indicates a poor prognosis in hepatocellular carcinoma

Yifeng Wu, Xianpeng Li, Mingliang Chen, Zhikun Liu, Xuanyu Zhang, Shusen Zheng, Xiao Xu
Article Number: 177
Published online on: 06 January 2021

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Phosphorylated form of pyruvate dehydrogenase α1 mediates tumor necrosis factor α‑induced glioma cell migration

Zijun Yang, Yidan Wang, Li Zhang, Chenjin Zhao, Donglin Wang
Article Number: 176
Published online on: 06 January 2021

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[Corrigendum] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 175
Published online on: 05 January 2021

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January-2026 Volume 31 Issue 1

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CiteScore: 4.6

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SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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