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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2020 Volume 21 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

The potential roles of circular RNAs in osteonecrosis of the femoral head (Review)

Jun Zhao, Long Mu, Zhengchun Wang, Xiangchun Fang, Xuefeng He, Xiaofeng Zhang, Xilin Xu
Pages: 533-539
Published online on: 06 December 2019

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Metabolic disparities of different oxidative stress‑inducing conditions in HTR8/SVneo cells

Jingdong Chen, Ting‑Li Han, Xiaobo Zhou, Philip Baker, Yong Shao, Hua Zhang
Pages: 540-548
Published online on: 05 December 2019

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Article Open Access

Swimming exercise inhibits myocardial ER stress in the hearts of aged mice by enhancing cGMP‑PKG signaling

Pan Chang, Xiaomeng Zhang, Mingyang Zhang, Guohua Li, Lang Hu, Huishou Zhao, Xiaoxing Zhu, Juan Wu, Xihui Wang, Kaiyan Wang, Jing Zhang, Minggang Ren, Baoying Chen, Xiaoling Zhu, Miaozhang Zhu, Jun Yu
Pages: 549-556
Published online on: 05 December 2019

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Article Open Access

Identification of key genes as potential biomarkers for triple‑negative breast cancer using integrating genomics analysis

Guansheng Zhong, Weiyang Lou, Qinyan Shen, Kun Yu, Yajuan Zheng
Pages: 557-566
Published online on: 06 December 2019

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Article Open Access

Endoplasmic reticulum stress induces liver cells apoptosis after brain death by suppressing the phosphorylation of protein phosphatase 2A

Jia'nan Lan, Zibiao Zhong, Yanfeng Wang, Yan Xiong, Qifa Ye
Pages: 567-574
Published online on: 10 December 2019

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Article Open Access

Function of fibroblast growth factor 2 in gastric cancer occurrence and prognosis

Yang Li, Xiao‑Bo Guo, Jin Shen Wang, Hong‑Chang Wang, Le‑Ping Li
Pages: 575-582
Published online on: 26 November 2019

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Article Open Access

Notch inhibitor mitigates renal ischemia‑reperfusion injury in diabetic rats

Xiaokai Duan, Guijun Qin
Pages: 583-588
Published online on: 04 December 2019

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Article Open Access

Downregulation of long non‑coding RNA ANRIL promotes proliferation and migration in hypoxic human pulmonary artery smooth muscle cells

Siqi Wang, Chen Zhang, Xiaodan Zhang
Pages: 589-596
Published online on: 17 December 2019

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Article Open Access

Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells

Hao He, Chang Xu, Lei Zheng, Kaidi Wang, Manfei Jin, Yanping Sun, Zhenggang Yue
Pages: 597-606
Published online on: 12 December 2019

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Article Open Access

Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury

Min Li, Xiang‑Zhi Fang, Xiao‑Tian Liu, Yong‑Feng Zheng, Yun‑Bin Xie, Xiao‑Dong Ma, Yan Xia, Dong‑Hua Shao
Pages: 607-614
Published online on: 26 November 2019

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Article Open Access

Effect of the alteration of Tribbles homologue 3 expression on epithelial‑mesenchymal transition of transforming growth factor β1‑induced mouse alveolar epithelial cells through the Wnt/β‑catenin signaling pathway

Wencheng Yu, Liyun Mi, Feifei Wang
Pages: 615-622
Published online on: 05 December 2019

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Article Open Access

Low molecular weight heparin (nadroparin) improves placental permeability in rats with gestational diabetes mellitus via reduction of tight junction factors

Yuehua Shi, Jie Qian, Feng Zhang, Beibei Jia, Xiaoyan Liu, Yan Hu, Qinfen Zhang, Ye Yang, Dongdong Sun, Li Jiang
Pages: 623-630
Published online on: 06 December 2019

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Article Open Access

Cardiac shock wave therapy protects cardiomyocytes from hypoxia‑induced injury by modulating miR‑210

Quan Qiu, Tao Shen, Que Wang, Xiaoxue Yu, Na Jia, Qing He
Pages: 631-640
Published online on: 18 December 2019

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Article Open Access

Crocetin alleviates myocardial ischemia/reperfusion injury by regulating inflammation and the unfolded protein response

Ming Yang, Genxiang Mao, Lili Ouyang, Chenhui Shi, Pengfei Hu, Shuwei Huang
Pages: 641-648
Published online on: 17 December 2019

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Article Open Access

Long intergenic non‑protein coding RNA 00460 predicts a poor prognosis and promotes tumorigenesis of human osteosarcoma

Jian‑Jun Jiang, Feng‑Chao Wang, Li‑Ping Han
Pages: 649-658
Published online on: 04 December 2019

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Article Open Access

Expression pattern of placenta specific 8 and keratin 20 in different types of gastrointestinal cancer

Chih‑Sheng Hung, Yen‑Chieh Wang, Jiun‑Wen Guo, Ruey‑Neng Yang, Chia‑Long Lee, Ming‑Hung Shen, Chi‑Cheng Huang, Chi‑Jung Huang, Jhih‑Yun Yang, Chih‑Yi Liu
Pages: 659-666
Published online on: 06 December 2019

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Article Open Access

Class C1 decoy oligodeoxynucleotide inhibits profibrotic genes expression in rat hepatic stellate cells

Chun Rao, Yi‑Ran Ni, Yan‑Min Zhao, Yan‑Qiong Zhang, Rui‑Ting Zhou, Chang‑Bai Liu, Lin Han, Jiang‑Feng Wu
Pages: 667-674
Published online on: 13 December 2019

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Article Open Access

Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway

Yong Zhang, Qiuyan Weng, Jinming Han, Jianming Chen
Pages: 675-684
Published online on: 13 December 2019

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Article Open Access

Identification of hub genes and key pathways of dietary advanced glycation end products‑induced non‑alcoholic fatty liver disease by bioinformatics analysis and animal experiments

Jiao Wang, Honghong Liu, Guijiao Xie, Wei Cai, Jixiong Xu
Pages: 685-694
Published online on: 09 December 2019

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Article Open Access

Inhibition of the SIRT1 signaling pathway exacerbates endoplasmic reticulum stress induced by renal ischemia/reperfusion injury in type 1 diabetic rats

Jianjian Zhang, Lei Wang, Daojing Gong, Yuanyuan Yang, Xiuheng Liu, Zhiyuan Chen
Pages: 695-704
Published online on: 18 December 2019

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Article Open Access

miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10

Zishu Wang, Lun Yao, Yu Li, Bo Hao, Mingxi Wang, Junbin Wang, Wei Gu, Huihui Zhan, Guoquan Liu, Qiong Wu
Pages: 705-719
Published online on: 29 November 2019

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Article Open Access

Carboxyl terminal activating region 3 of latent membrane protein 1 encoded by the Epstein‑Barr virus regulates cell proliferation and protein expression in NP69 cells

Zhi‑Wei Zhang, He‑Liang Zhang, Yan‑Hui Yu, Yong‑Mei Ouyang, Zhu‑Chu Chen, Xiu‑Sheng He, Zhi-Min He
Pages: 720-730
Published online on: 04 December 2019

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Article Open Access

Comparative proteomic and genomic analyses of Brucella abortus biofilm and planktonic cells

Taishan Tang, Guoqiang Chen, Aizhen Guo, Ye Xu, Linli Zhao, Mengrui Wang, Chengping Lu, Yuan Jiang, Changyin Zhang
Pages: 731-743
Published online on: 17 December 2019

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Article Open Access

Identification of aberrantly methylated‑differentially expressed genes and gene ontology in prostate cancer

Linbang Wang, Bing Wang, Zhengxue Quan
Pages: 744-758
Published online on: 11 December 2019

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Article Open Access

Affinity improvement of the fully human anti‑TSLP recombinant antibody

Qi Chen, Dequn Xian, Wenfeng Xu, Siji Nian, Hong Yu, Yuchuan Wu, Qing Yuan
Pages: 759-767
Published online on: 12 December 2019

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Article Open Access

Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p

Guangyu Jiang, Hang Dong, Yu Dong, Xinyu Yang
Pages: 768-776
Published online on: 26 November 2019

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Article Open Access

Protein kinase C promotes choline transporter‑like protein 1 function via improved cell surface expression in immortalized human hepatic cells

Takuya Ishikawa, Hirotsugu Suwanai, Junpei Shikuma, Ryo Suzuki, Tsuyoshi Yamanaka, Masato Odawara, Masato Inazu
Pages: 777-785
Published online on: 18 December 2019

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Article Open Access

Expression profile of Toll‑like receptors in human breast cancer

Shuxun Shi, Cong Xu, Xiaonan Fang, Yonghuan Zhang, Hua Li, Wujun Wen, Guiwen Yang
Pages: 786-794
Published online on: 26 November 2019

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Article Open Access

BAFF is involved in the pathogenesis of IgA nephropathy by activating the TRAF6/NF‑κB signaling pathway in glomerular mesangial cells

Yingjie Cao, Guoyuan Lu, Xiaolan Chen, Xu Chen, Naifeng Guo, Wenwen Li
Pages: 795-805
Published online on: 06 December 2019

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Article Open Access

Effect of SKF‑96365 on cardiomyocyte hypertrophy induced by angiotensin II

Huijun Cheng, Jiaoxia Li, Qiyan Wu, Xiaodong Zheng, Yongqiang Gao, Qiaofen Yang, Ningxi Sun, Meiqiong He, Youjun Zhou
Pages: 806-814
Published online on: 11 December 2019

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Article Open Access

CircRNA expression profiles in human visceral preadipocytes and adipocytes

Wenxing Sun, Xuecheng Sun, Weiwei Chu, Shigang Yu, Fulu Dong, Guangfei Xu
Pages: 815-821
Published online on: 16 December 2019

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Article Open Access

High HDAC9 is associated with poor prognosis and promotes malignant progression in pancreatic ductal adenocarcinoma

He Li, Xiaocheng Li, Huapeng Lin, Jianping Gong
Pages: 822-832
Published online on: 06 December 2019

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Article Open Access

Overexpression of BMP‑7 reverses TGF‑β1‑induced epithelial‑mesenchymal transition by attenuating the Wnt3/β‑catenin and TGF-β1/Smad2/3 signaling pathways in HK‑2 cells

Yan Song, Shasha Lv, Fang Wang, Xiaoli Liu, Jing Cheng, Shanshan Liu, Xiaoying Wang, Wei Chen, Guangju Guan, Gang Liu, Changliang Peng
Pages: 833-841
Published online on: 10 December 2019

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Article Open Access

CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway

Rui‑Ying Wang, Xiao‑Wei Chen, Wen‑Wen Zhang, Fei Jiang, Meng‑Qi Liu, Xiao‑Bing Shen
Pages: 842-850
Published online on: 17 December 2019

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Article Open Access

Hexavalent chromium intoxication induces intrinsic and extrinsic apoptosis in human renal cells

Yen‑Hung Wu, Jhong‑Ching Lin, Tzu‑Yi Wang, Tzeng‑Jih Lin, Meng‑Chi Yen, Yao‑Hua Liu, Pei‑Lin Wu, Fen‑Wei Chen, Yueh‑Lun Shih, I‑Jeng Yeh
Pages: 851-857
Published online on: 16 December 2019

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Article Open Access

ΜicroRNA‑421 participates in vitiligo development through regulating human melanocyte survival by targeting receptor‑interacting serine/threonine kinase 1

Xuecheng Sun, Tao Wang, Bo Huang, Gaobo Ruan, Aie Xu
Pages: 858-866
Published online on: 11 December 2019

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Article Open Access

SHOC2 is associated with the survival of breast cancer cells and has prognostic value for patients with breast cancer

Wenwen Geng, Ke Dong, Qian Pu, Yanrong Lv, Haidong Gao
Pages: 867-875
Published online on: 17 December 2019

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Article Open Access

Role of adenosine deaminase 2 gene variants in pediatric deficiency of adenosine deaminase 2: A structural biological approach Corrigendum in /10.3892/mmr.2021.12128

Maria I. Zervou, George N. Goulielmos, Michail Matalliotakis, Charoula Matalliotaki, Demetrios A. Spandidos, Elias Eliopoulos
Pages: 876-882
Published online on: 05 December 2019

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Article Open Access

Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation Corrigendum in /10.3892/mmr.2021.12295

Fangce Wang, Zheng Li, Guangming Wang, Xiaoxue Tian, Jie Zhou, Wenlei Yu, Zhuoyi Fan, Lin Dong, Jinyuan Lu, Jun Xu, Wenjun Zhang, Aibin Liang
Pages: 883-893
Published online on: 26 November 2019

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Article

Genetic characterization of variants of HPV‑16, HPV‑18 and HPV‑52 circulating in Italy among general and high‑risk populations

Elena Rosanna Frati, Silvia Bianchi, Antonella Amendola, Daniela Colzani, Fabio Petrelli, Gianguglielmo Zehender, Elisabetta Tanzi
Pages: 894-902
Published online on: 25 November 2019

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Article

Anti‑restriction protein KlcAHS enhances carbapenem resistance

Wei Liang, Cheng Zhao, Yan Wang, Wenjun Zhu, Ying Zhang, Juan Hu, Xia Liu, Lin Yang, Wanchuan Zhuang, Yuping Shang, Guanhong Huang, Hui Shi
Pages: 903-908
Published online on: 16 December 2019

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Article

Oridonin enhances γ‑globin expression in erythroid precursors from patients with β‑thalassemia via activation of p38 MAPK signaling

Lishan Guo, Jia Chen, Qianying Wang, Junliang Zhang, Weimin Huang
Pages: 909-917
Published online on: 25 November 2019

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Article

Molecular cytogenetic characterization of an isodicentric Yq and a neocentric isochromosome Yp in an azoospermic male

Yuting Jiang, Fagui Yue, Ruixue Wang, Hongguo Zhang, Leilei Li, Linlin Li, Shibo Li, Ruizhi Liu
Pages: 918-926
Published online on: 13 December 2019

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Article

Synergistic effect of halofuginone and dexamethasone on LPS‑induced acute lung injury in type II alveolar epithelial cells and a rat model

Hai‑Lian Du, Ai‑Dong Zhai, Hong Yu
Pages: 927-935
Published online on: 06 December 2019

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Article

Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells

Zuofei Chi, Hongyu Gao, Hui Liu, Bin Wu, Bin Zhang, Min Gu, Wei Yang
Pages: 936-944
Published online on: 10 December 2019

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Article

Leptin receptor mediates the proliferation and glucose metabolism of pancreatic cancer cells via AKT pathway activation

Yingjie Xu, Meiyu Tan, Xiaoyu Tian, Jun Zhang, Jie Zhang, Jiajie Chen, Weihong Xu, Huiming Sheng
Pages: 945-952
Published online on: 29 November 2019

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Article

Optimal conditions for the storage of German cockroach extract

Kyoung Yong Jeong, Jongsun Lee, Ji‑Eun Yuk, Kyung Hee Park, Jae‑Hyun Lee, Jung Dong Kim, Jung‑Won Park
Pages: 953-958
Published online on: 27 November 2019

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Article

DNA methyltransferase DNMT1 inhibits lipopolysaccharide‑induced inflammatory response in human dental pulp cells involving the methylation changes of IL‑6 and TRAF6

Luhui Cai, Minkang Zhan, Qimeng Li, Di Li, Qiong Xu
Pages: 959-968
Published online on: 04 December 2019

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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