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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2020 Volume 19 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Overview of the STAT‑3 signaling pathway in cancer and the development of specific inhibitors (Review)

Yuchen Gu, Imran Shair Mohammad, Zhe Liu
Pages: 2585-2594
Published online on: 13 February 2020

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Review Open Access

Role and mechanism of programmed death‑ligand 1 in hypoxia‑induced liver cancer immune escape (Review)

Qingxian Wen, Tao Han, Zijian Wang, Shulong Jiang
Pages: 2595-2601
Published online on: 05 February 2020

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Article Open Access

Podoplanin is an efficient predictor of neck lymph node metastasis in tongue squamous cell carcinoma with low tumor budding grade

Mei Hamada, Yasuhiro Ebihara, Koji Nagata, Mitsutake Yano, Yasunao Kogashiwa, Mitsuhiko Nakahira, Masashi Sugasawa, Hitoshi Nagatsuka, Masanori Yasuda
Pages: 2602-2608
Published online on: 29 January 2020

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Article Open Access

Association between G‑protein coupled receptor 4 expression and microvessel density, clinicopathological characteristics and survival in hepatocellular carcinoma

Chaofan Xue, Shuai Shao, Yanli Yan, Si Yang, Shuheng Bai, Yinying Wu, Jiangzhou Zhang, Rui Liu, Hailin Ma, Linyan Chai, Xiaozhi Zhang, Juan Ren
Pages: 2609-2620
Published online on: 05 February 2020

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Article Open Access

Maspin inhibits MCF‑7 cell invasion and proliferation by downregulating miR‑21 and increasing the expression of its target genes

Shao‑Xin Huang, Wen‑Yan Fan, Ling Wang, Hui Liu, Xin Wang, Hao Zhao, Wen‑Bin Jiang
Pages: 2621-2628
Published online on: 30 January 2020

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Article Open Access

Pharmacological ascorbate induces ‘BRCAness’ and enhances the effects of Poly(ADP‑Ribose) polymerase inhibitors against BRCA1/2 wild‑type ovarian cancer

Yan Ma, Ping Chen, Jeanne A. Drisko, Dineo Khabele, Andrew K. Godwin, Qi Chen
Pages: 2629-2638
Published online on: 31 January 2020

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Article Open Access

Decreased IL‑37 expression in hepatocellular carcinoma tissues and liver cancer cell lines

Peng Li, Hongsheng Guo, Kun Wu, Liudan Su, Kai Huang, Ruizhi Lai, Ziliang Deng, Shuxian Li, Ping Ouyang, Yan Wang, Zhangquan Chen, Guangji Zhou, Sen Wang
Pages: 2639-2648
Published online on: 13 February 2020

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Article Open Access

Interferon‑β sensitizes human glioblastoma cells to the cyclin‑dependent kinase inhibitor, TG02

Birthe Lohmann, Emilie Le Rhun, Manuela Silginer, Mirka Epskamp, Michael Weller
Pages: 2649-2656
Published online on: 30 January 2020

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Article Open Access

Usefulness of plasma full‑length glypican‑3 as a predictive marker of hepatocellular carcinoma recurrence after radial surgery

Masahiro Miura, Norihiro Fujinami, Yasuhiro Shimizu, Shoichi Mizuno, Keigo Saito, Toshihiro Suzuki, Masaru Konishi, Shinichiro Takahashi, Naoto Gotohda, Kouzou Suto, Tomokazu Yoshida, Tetsuya Nakatsura
Pages: 2657-2666
Published online on: 05 February 2020

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Article Open Access

Indication of suitable transarterial chemoembolization and multikinase inhibitors for intermediate stage hepatocellular carcinoma

Shigeo Shimose, Takumi Kawaguchi, Hideki Iwamoto, Takashi Niizeki, Tomotake Shirono, Masatoshi Tanaka, Hironori Koga, Takuji Torimura
Pages: 2667-2676
Published online on: 17 February 2020

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Article Open Access

miR‑3940‑5p/miR‑8069 ratio in urine exosomes is a novel diagnostic biomarker for pancreatic ductal adenocarcinoma

Naohiko Yoshizawa, Kazushi Sugimoto, Masahiko Tameda, Yuji Inagaki, Makoto Ikejiri, Hiroyuki Inoue, Masanobu Usui, Masaaki Ito, Yoshiyuki Takei
Pages: 2677-2684
Published online on: 29 January 2020

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Article Open Access

Upregulation of microRNA‑31 is associated with poor prognosis in patients with advanced colorectal cancer

Nobuhito Kubota, Fumitaka Taniguchi, Akihiro Nyuya, Yuzo Umeda, Yoshiko Mori, Toshiyoshi Fujiwara, Hiroaki Tanioka, Atsushi Tsuruta, Yoshiyuki Yamaguchi, Takeshi Nagasaka
Pages: 2685-2694
Published online on: 03 February 2020

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Article Open Access

Salvage stereotactic body radiotherapy for post‑operative oligo‑recurrence of non‑small cell lung cancer: A single‑institution analysis of 59 patients

Shuri Aoki, Hideomi Yamashita, Wataru Takahashi, Kanabu Nawa, Takeshi Ota, Toshikazu Imae, Sho Ozaki, Yuki Nozawa, Jun Nakajima, Masaaki Sato, Masaki Anraku, Junichi Nitadori, Takahiro Karasaki, Osamu Abe, Keiichi Nakagawa
Pages: 2695-2704
Published online on: 17 February 2020

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Article Open Access

The pathological complete response and secreted protein acidic and rich in cysteine expression in patients with breast cancer receiving neoadjuvant nab‑paclitaxel chemotherapy

Yuko Nakazawa, Seshiru Nakazawa, Sasagu Kurozumi, Misato Ogino, Yukio Koibuchi, Hiroki Odawara, Tetsunari Oyama, Jun Horiguchi, Takaaki Fujii, Ken Shirabe
Pages: 2705-2712
Published online on: 27 January 2020

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Article Open Access

Changes in the gene mutation profiles of circulating tumor DNA detected using CAPP‑Seq in neoadjuvant chemotherapy‑treated advanced ovarian cancer

Tomoko Noguchi, Kazuko Sakai, Naoyuki Iwahashi, Kaho Matsuda, Hitomi Matsukawa, Tamaki Yahata, Saori Toujima, Kazuto Nishio, Kazuhiko Ino
Pages: 2713-2720
Published online on: 28 January 2020

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Article Open Access

lncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial‑to‑mesenchymal transition Retraction in /10.3892/ol.2020.11949

Wenrui Xu, Xiaohan Sun, Chuanshan Zang, Yan Jiang
Pages: 2721-2726
Published online on: 14 February 2020

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Article Open Access

miR‑939‑3p promotes epithelial‑mesenchymal transition and may be used as a prognostic marker in hepatocellular carcinoma

Fei Chen, Xiaoying Ni, Lingxiu Chen, Xiaoyan Wang, Ji Xu
Pages: 2727-2732
Published online on: 30 January 2020

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Article Open Access

Influence of combined epidural anesthesia on cognitive function, inflammation and stress response in elderly liver cancer patients undergoing surgery

Yang Su, Yanan Pu, Zhengnan Zhao, Xianglong Yang
Pages: 2733-2738
Published online on: 14 February 2020

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Article Open Access

Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Li Li, Xiaosong Rao, Zhaohong Wen, Xiaosheng Ding, Xiangyi Wang, Weiran Xu, Chao Meng, Yuting Yi, Yanfang Guan, Yongshen Chen, Jiayin Wang, Liang Jun
Pages: 2739-2748
Published online on: 05 February 2020

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Article Open Access

SMAD3 promotes ELK3 expression following transforming growth factor β‑mediated stimulation of MDA‑MB231 cells

Ji‑Hoon Park, Kyung‑Soon Park
Pages: 2749-2754
Published online on: 06 February 2020

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Article Open Access

Expression of Foxp3 and interleukin‑7 receptor and clinicopathological characteristics of patients with diffuse large B‑cell lymphoma

Yan Zhao, Wen‑Li Cui, Zhi‑Yin Feng, Jing Xue, Abulajiang Gulinaer, Wei Zhang
Pages: 2755-2764
Published online on: 06 February 2020

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Article Open Access

Upregulation of MYBL2 independently predicts a poorer prognosis in patients with clear cell renal cell carcinoma

Shan‑Shan Sun, Yang Fu, Jian‑Yang Lin
Pages: 2765-2772
Published online on: 17 February 2020

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Article Open Access

Ubiquitin‑like modifier‑activating enzyme 7 as a marker for the diagnosis and prognosis of breast cancer

Meng Lin, Yanqing Li, Shanshan Qin, Yan Jiao, Fang Hua
Pages: 2773-2784
Published online on: 17 February 2020

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Article Open Access

Evaluation of kininogen 1, osteopontin and α‑1‑antitrypsin in plasma, bronchoalveolar lavage fluid and urine for lung squamous cell carcinoma diagnosis

Weiwei Wang, Shanshan Wang, Man Zhang
Pages: 2785-2792
Published online on: 06 February 2020

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Article Open Access

Identification of a long non‑coding RNA signature for predicting prognosis and biomarkers in lung adenocarcinoma

Xiaolin Yu, Yanxia Zhang
Pages: 2793-2800
Published online on: 17 February 2020

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Article Open Access

4‑methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight‑hyaluronan in fibrosarcoma cells

Kazuki Hasegawa, Ryo Saga, Rei Takahashi, Roman Fukui, Mitsuru Chiba, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa
Pages: 2801-2808
Published online on: 05 February 2020

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Article Open Access

A novel anti‑EGFR monoclonal antibody (EMab‑17) exerts antitumor activity against oral squamous cell carcinomas via antibody‑dependent cellular cytotoxicity and complement‑dependent cytotoxicity

Junko Takei, Mika Kato Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato
Pages: 2809-2816
Published online on: 10 February 2020

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Article Open Access

Gene expression profiling identified TP53MutPIK3CAWild as a potential biomarker for patients with triple‑negative breast cancer treated with immune checkpoint inhibitors

Jia'nan Cheng, Xiaofang Ding, Shouxia Xu, Bo Zhu, Qingzhu Jia
Pages: 2817-2824
Published online on: 10 February 2020

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Article Open Access

PEBP4 gene expression in lung squamous cell carcinoma: A meta‑analysis‑based study of the molecular pathways involved

Guiping Yu, Ning Zhong, Bin Huang, Yedong Mi
Pages: 2825-2831
Published online on: 12 February 2020

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Article Open Access

LINK‑A lncRNA is upregulated in osteosarcoma and regulates migration, invasion and stemness of osteosarcoma cells

Yao Kong, Zhikui Nie, Hongmin Guo, Cao Ma
Pages: 2832-2838
Published online on: 05 February 2020

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Article Open Access

Knockdown of long non‑coding RNA prostate cancer‑associated transcript 1 inhibits the proliferation and metastasis of tongue squamous cell carcinoma cells by upregulating p21

Ming Yan, Tianjiang Zhao, Lingling Fu, Rongxiang Tian, Dongzhen Li, Yunmeng Da
Pages: 2839-2845
Published online on: 06 February 2020

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Article Open Access

Identification of hub genes associated with outcome of clear cell renal cell carcinoma

Rengui Li, Lei Wang, Xiao Wang, Rong‑Xin Geng, Ning Li, Xiu‑Heng Liu
Pages: 2846-2860
Published online on: 12 February 2020

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Article Open Access

Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes

Li‑Rong Ling, Dan‑Hua Zheng, Zhi‑Yang Zhang, Wen‑Hui Xie, Yue‑Hong Huang, Zhi‑Xin Chen, Xiao‑Zhong Wang, Dan Li
Pages: 2861-2869
Published online on: 17 February 2020

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Article Open Access

GEM on proliferation and apoptosis of childhood AL cells through inhibiting c‑myc expression by upregulating miR‑125a‑3p

Weiwei Xing, Yuxia Yin, Saina Yang, Guang Lu
Pages: 2870-2874
Published online on: 14 February 2020

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Article Open Access

C‑C motif chemokine 14 as a novel potential biomarker for predicting the prognosis of epithelial ovarian cancer

Yubo Cai, Yihong Ling, Lingbo Huang, Hui Huang, Xianlan Chen, Yongbo Xiao, Zhongmei Zhu, Jiewei Chen
Pages: 2875-2883
Published online on: 07 February 2020

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Article Open Access

De novo metastatic breast cancer: Subgroup analysis of molecular subtypes and prognosis

Li Zhang, Zhijun Li, Jie Zhang, Yansheng Wu, Yuying Zhu, Zhongsheng Tong
Pages: 2884-2894
Published online on: 30 January 2020

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Article Open Access

RBBP6 induces non‑small cell lung cancer cell proliferation and high expression is associated with poor prognosis

Qiu‑Shi Wang, Shi‑Rong Wei, Hua‑Liang Xiao
Pages: 2895-2901
Published online on: 17 February 2020

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Article Open Access

MicroRNA‑212 suppresses cell proliferation in nasopharyngeal carcinoma by targeting ELF3

Yaojie Kang, Yanfei Cui, Ming Tan
Pages: 2902-2908
Published online on: 17 February 2020

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Article Open Access

Effects of CDK6 regulated by miR‑298 on proliferation and apoptosis of thyroid cancer cells

Xinyan Li, Cuicui Liu, Xiumei Zhao, Rui Wang, Na Gu, Hongsheng Shen, Xijing Li, Luyao Wang, Chao Li
Pages: 2909-2915
Published online on: 14 February 2020

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Article Open Access

BCL11A confers cell invasion and migration in androgen receptor‑positive triple‑negative breast cancer

Xin Wang, Yumei Xu, Kun Xu, Yajuan Chen, Xiudi Xiao, Xiaoxiang Guan
Pages: 2916-2924
Published online on: 10 February 2020

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Article Open Access

Heavy metals interfere with plasma metabolites, including lipids and amino acids, in patients with breast cancer

Ling Li, Meihua Zhang, Yuhao Men, Wei Wang, Weidong Zhang
Pages: 2925-2933
Published online on: 17 February 2020

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Article Open Access

Intratumoral heterogeneity of glutaminase and lactate dehydrogenase A protein expression in colorectal cancer

Yuta Mizuno, Kimiaki Hattori, Kohei Taniguchi, Keitaro Tanaka, Kazuhisa Uchiyama, Yoshinobu Hirose
Pages: 2934-2942
Published online on: 13 February 2020

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Article Open Access

Timing of changing therapy from gemcitabine and cisplatin chemotherapy based on real‑world data of advanced urothelial carcinoma

Nobuki Furubayashi, Takahito Negishi, Dai Takamatsu, Kosuke Ieiri, Tomohiro Inoue, Keiji Tsukino, Motonobu Nakamura
Pages: 2943-2949
Published online on: 05 February 2020

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Article Open Access

Rapamycin inhibits proliferation and apoptosis of retinoblastoma cells through PI3K/AKT signaling pathway

Jun Yao, Min Xu, Ziyao Liu
Pages: 2950-2956
Published online on: 30 January 2020

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Case Report

Complex karyotype with cryptic FUS gene rearrangement and deletion of NR3C1 and VPREB1 genes in childhood B‑cell acute lymphoblastic leukemia: A case report

Moneeb A.K. Othman, Marina Đurišić, Gordana Samardzija, Dragana Vujić, Nina Lakic, Zeljko Zecevic, Fawaz Al‑Shaheri, Rouben Aroutiounian, Joana B. Melo, Isabel M. Carreira, Britta Meyer, Thomas Liehr
Pages: 2957-2962
Published online on: 12 February 2020

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Article

Pristimerin inhibits the proliferation of HT1080 fibrosarcoma cells by inducing apoptosis

Daichi Hayashi, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Yuji Arai, Osam Mazda, Toshikazu Kubo
Pages: 2963-2970
Published online on: 17 February 2020

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Article

Comprehensive circular RNA profiling reveals the regulatory role of circ_100242/miR-145 pathway in bladder cancer

Zhaowei Zhu, Fujiang Chang, Junxiao Liu, Jiange Wang, Xuepei Zhang
Pages: 2971-2978
Published online on: 10 February 2020

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Article

Development of a nine‑lncRNA signature as a novel prognostic marker of estrogen receptor‑negative breast cancer

Zhiwei Wang, Jie Wang, Lei Liu, Qi He, Min Wei
Pages: 2979-2988
Published online on: 13 February 2020

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Article

NOS1 expression promotes proliferation and invasion and enhances chemoresistance in ovarian cancer

Zhiwei Zou, Xiaoxuan Li, Yongliang Sun, Linlin Li, Qianbing Zhang, Lingqun Zhu, Zhuo Zhong, Meng Wang, Qianli Wang, Zhenjun Liu, Yifeng Wang, Yifang Ping, Kaitai Yao, Bingtao Hao, Qiuzhen Liu
Pages: 2989-2995
Published online on: 27 January 2020

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Article

Determination of the optimal detection time of circulating tumor cells for the postoperative monitoring of colorectal cancer

Tianchen Huang, Cheng Xu, Jianan Xiao, Qingbing Wang, Yanjun Wang, Yong Zhang, Dongxiao Bai, Fuyou Zhou, Xiaoyu Zhao
Pages: 2996-3002
Published online on: 12 February 2020

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Article

Methylation profiling in promoter sequences of ATM and CDKN2A (p14ARF/p16INK4a) genes in blood and cfDNA from women with impalpable breast lesions

Lucas Delmonico, Mauricio Augusto Silva Magalhães Costa, Romario José Gomes, Pâmella de Oliveira Vieira, Ana Beatriz Passos da Silva, Marcia V. Fournier, Luciano Rios Scherrer, Carolina Maria de Azevedo, Maria Helena Faria Ornellas, Gilda Alves
Pages: 3003-3010
Published online on: 10 February 2020

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Article

Serum melatonin is inversely associated with matrix metalloproteinase‑9 in oral squamous cell carcinoma

Adina Elena Stanciu, Adina Zamfir‑Chiru‑Anton, Marcel Marian Stanciu, Anca Pantea‑Stoian, Cornelia Nitipir, Dan Cristian Gheorghe
Pages: 3011-3020
Published online on: 13 February 2020

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Article

Potential synergistic effects of sorafenib and CP‑31398 for treating anaplastic thyroid cancer with p53 mutations

Jiin‑Torng Wu, Ching‑Ling Lin, Chi‑Jung Huang, Yu‑Che Cheng, Chih‑Cheng Chien, Yung‑Chuan Sung
Pages: 3021-3026
Published online on: 07 February 2020

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Article

Sasa quelpaertensis Nakai extract induces p53‑independent apoptosis via the elevation of nitric oxide production in human HCT116 colon cancer cells

Min Young Kim
Pages: 3027-3034
Published online on: 10 February 2020

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Correction Open Access

[Erratum] Peripheral primitive neuroectodermal tumors: A retrospective analysis of 89 cases and literature review

Liming Gao, Yingying Zhu, Xiaohua Shi, Zhiqiang Gao, Xingming Chen
Pages: 3035-3035
Published online on: 12 February 2020

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Review Open Access

Association of oral dysbiosis with oral cancer development (Review)

Giusy Rita Maria La Rosa, Giuseppe Gattuso, Eugenio Pedullà, Ernesto Rapisarda, Daria Nicolosi, Mario Salmeri
Pages: 3045-3058
Published online on: 03 March 2020

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Review Open Access

The roles of curcumin in regulating the tumor immunosuppressive microenvironment (Review)

Yizhi Wang, Jun Lu, Bolun Jiang, Junchao Guo
Pages: 3059-3070
Published online on: 03 March 2020

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Article Open Access

Long non‑coding RNA BRM promotes proliferation and invasion of papillary thyroid carcinoma by regulating the microRNA‑331‑3p/SLC25A1 axis

Shihong Liu, Deping Zhang, Li Chen, Shangfang Gao, Xiu Huang
Pages: 3071-3078
Published online on: 20 February 2020

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Article Open Access

microRNA‑144 inhibits cell proliferation and invasion by directly targeting TIGAR in esophageal carcinoma

Yushu Mu, Qifei Wang, Lei Tan, Lin Lin, Benhua Zhang
Pages: 3079-3088
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Texture analysis of early cerebral tissue damage in magnetic resonance imaging of patients with lung cancer

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Comprehensive genomic profile of cholangiocarcinomas in China

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Increased expression of the RNA‑binding motif protein 47 predicts poor prognosis in non‑small‑cell lung cancer

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METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway

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Advanced glycation end products induce proliferation, invasion and epithelial‑mesenchymal transition of human SW480 colon cancer cells through the PI3K/AKT signaling pathway

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Pages: 3215-3222
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Hematoporphyrin monomethyl ether‑mediated sonodynamic therapy induces A‑253 cell apoptosis

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miR‑320/ELF3 axis inhibits the progression of breast cancer via the PI3K/AKT pathway

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Early risk warning system for distant metastasis of hepatitis B virus‑associated hepatocellular carcinoma with portal vein tumor thrombus

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Cell proliferation is induced in renal cell carcinoma through miR‑92a‑3p upregulation by targeting FBXW7

Rong Zeng, Jing Huang, Yujie Sun, Juan Luo
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Autophagy suppresses resveratrol‑induced apoptosis in renal cell carcinoma 786‑O cells

Hongwei Yao, Min Fan, Xiaozhou He
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Associations of sirtuins with clinicopathological variables and prognosis in human ovarian cancer

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MicroRNA‑21 promotes cell metastasis in cervical cancer through modulating epithelial‑mesenchymal transition

Yaling Tang, Yan Zhao, Jing Ran, Yifeng Wang
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Profiles of m6A RNA methylation regulators for the prognosis of hepatocellular carcinoma

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Upregulation of ASPM, BUB1B and SPDL1 in tumor tissues predicts poor survival in patients with pancreatic ductal adenocarcinoma

Xiong Tian, Na Wang
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Comprehensive gene and pathway analysis of cervical cancer progression

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Pages: 3316-3332
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Semaphorin‑4C is upregulated in epithelial ovarian cancer

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Downregulation of TMOD1 promotes cell motility and cell proliferation in cervical cancer cells

Fangjin Lu, Dandan Cui, Bin Mu, Lu Zhao, Ping Mu
Pages: 3339-3348
Published online on: 19 February 2020

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RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signaling

Sujing Zhuang, Li Li, Yuwei Zang, Guangfeng Li, Feng Wang
Pages: 3349-3355
Published online on: 03 March 2020

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Correction Open Access

[Corrigendum] Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3356-3356
Published online on: 18 February 2020

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Correction Open Access

[Corrigendum] MicroRNA‑152 suppresses cisplatin resistance in A549 cells

Wenfei Zhao, Hongyun Li, Shanshan Yang, Di Guo, Jing Chen, Shaoyi Miao, Yi Xin, Miaomiao Liang
Pages: 3357-3357
Published online on: 28 February 2020

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Correction Open Access

[Corrigendum] P130cas is required for TGF‑β1‑mediated epithelial‑mesenchymal transition in lung cancer

Bo Deng, Qun‑You Tan, Ru‑Wen Wang, Yao‑Guang Jiang, Jing‑Hai Zhou, Wei Huang
Pages: 3358-3358
Published online on: 20 February 2020

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Correction Open Access

[Corrigendum] Loss of E‑cadherin promotes prostate cancer metastasis via upregulation of metastasis‑associated gene 1 expression

Liangsheng Fan, Hongyan Wang, Xi Xia, Yumei Rao, Xiangyi Ma, Ding Ma, Peng Wu, Gang Chen
Pages: 3359-3359
Published online on: 28 February 2020

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CiteScore Rank: Q2: #178/415 Oncology

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Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
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Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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