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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2020 Volume 19 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Overview of the STAT‑3 signaling pathway in cancer and the development of specific inhibitors (Review)

Yuchen Gu, Imran Shair Mohammad, Zhe Liu
Pages: 2585-2594
Published online on: 13 February 2020

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Review Open Access

Role and mechanism of programmed death‑ligand 1 in hypoxia‑induced liver cancer immune escape (Review)

Qingxian Wen, Tao Han, Zijian Wang, Shulong Jiang
Pages: 2595-2601
Published online on: 05 February 2020

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Article Open Access

Podoplanin is an efficient predictor of neck lymph node metastasis in tongue squamous cell carcinoma with low tumor budding grade

Mei Hamada, Yasuhiro Ebihara, Koji Nagata, Mitsutake Yano, Yasunao Kogashiwa, Mitsuhiko Nakahira, Masashi Sugasawa, Hitoshi Nagatsuka, Masanori Yasuda
Pages: 2602-2608
Published online on: 29 January 2020

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Article Open Access

Association between G‑protein coupled receptor 4 expression and microvessel density, clinicopathological characteristics and survival in hepatocellular carcinoma

Chaofan Xue, Shuai Shao, Yanli Yan, Si Yang, Shuheng Bai, Yinying Wu, Jiangzhou Zhang, Rui Liu, Hailin Ma, Linyan Chai, Xiaozhi Zhang, Juan Ren
Pages: 2609-2620
Published online on: 05 February 2020

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Article Open Access

Maspin inhibits MCF‑7 cell invasion and proliferation by downregulating miR‑21 and increasing the expression of its target genes

Shao‑Xin Huang, Wen‑Yan Fan, Ling Wang, Hui Liu, Xin Wang, Hao Zhao, Wen‑Bin Jiang
Pages: 2621-2628
Published online on: 30 January 2020

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Article Open Access

Pharmacological ascorbate induces ‘BRCAness’ and enhances the effects of Poly(ADP‑Ribose) polymerase inhibitors against BRCA1/2 wild‑type ovarian cancer

Yan Ma, Ping Chen, Jeanne A. Drisko, Dineo Khabele, Andrew K. Godwin, Qi Chen
Pages: 2629-2638
Published online on: 31 January 2020

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Article Open Access

Decreased IL‑37 expression in hepatocellular carcinoma tissues and liver cancer cell lines

Peng Li, Hongsheng Guo, Kun Wu, Liudan Su, Kai Huang, Ruizhi Lai, Ziliang Deng, Shuxian Li, Ping Ouyang, Yan Wang, Zhangquan Chen, Guangji Zhou, Sen Wang
Pages: 2639-2648
Published online on: 13 February 2020

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Article Open Access

Interferon‑β sensitizes human glioblastoma cells to the cyclin‑dependent kinase inhibitor, TG02

Birthe Lohmann, Emilie Le Rhun, Manuela Silginer, Mirka Epskamp, Michael Weller
Pages: 2649-2656
Published online on: 30 January 2020

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Article Open Access

Usefulness of plasma full‑length glypican‑3 as a predictive marker of hepatocellular carcinoma recurrence after radial surgery

Masahiro Miura, Norihiro Fujinami, Yasuhiro Shimizu, Shoichi Mizuno, Keigo Saito, Toshihiro Suzuki, Masaru Konishi, Shinichiro Takahashi, Naoto Gotohda, Kouzou Suto, Tomokazu Yoshida, Tetsuya Nakatsura
Pages: 2657-2666
Published online on: 05 February 2020

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Article Open Access

Indication of suitable transarterial chemoembolization and multikinase inhibitors for intermediate stage hepatocellular carcinoma

Shigeo Shimose, Takumi Kawaguchi, Hideki Iwamoto, Takashi Niizeki, Tomotake Shirono, Masatoshi Tanaka, Hironori Koga, Takuji Torimura
Pages: 2667-2676
Published online on: 17 February 2020

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Article Open Access

miR‑3940‑5p/miR‑8069 ratio in urine exosomes is a novel diagnostic biomarker for pancreatic ductal adenocarcinoma

Naohiko Yoshizawa, Kazushi Sugimoto, Masahiko Tameda, Yuji Inagaki, Makoto Ikejiri, Hiroyuki Inoue, Masanobu Usui, Masaaki Ito, Yoshiyuki Takei
Pages: 2677-2684
Published online on: 29 January 2020

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Article Open Access

Upregulation of microRNA‑31 is associated with poor prognosis in patients with advanced colorectal cancer

Nobuhito Kubota, Fumitaka Taniguchi, Akihiro Nyuya, Yuzo Umeda, Yoshiko Mori, Toshiyoshi Fujiwara, Hiroaki Tanioka, Atsushi Tsuruta, Yoshiyuki Yamaguchi, Takeshi Nagasaka
Pages: 2685-2694
Published online on: 03 February 2020

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Article Open Access

Salvage stereotactic body radiotherapy for post‑operative oligo‑recurrence of non‑small cell lung cancer: A single‑institution analysis of 59 patients

Shuri Aoki, Hideomi Yamashita, Wataru Takahashi, Kanabu Nawa, Takeshi Ota, Toshikazu Imae, Sho Ozaki, Yuki Nozawa, Jun Nakajima, Masaaki Sato, Masaki Anraku, Junichi Nitadori, Takahiro Karasaki, Osamu Abe, Keiichi Nakagawa
Pages: 2695-2704
Published online on: 17 February 2020

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Article Open Access

The pathological complete response and secreted protein acidic and rich in cysteine expression in patients with breast cancer receiving neoadjuvant nab‑paclitaxel chemotherapy

Yuko Nakazawa, Seshiru Nakazawa, Sasagu Kurozumi, Misato Ogino, Yukio Koibuchi, Hiroki Odawara, Tetsunari Oyama, Jun Horiguchi, Takaaki Fujii, Ken Shirabe
Pages: 2705-2712
Published online on: 27 January 2020

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Article Open Access

Changes in the gene mutation profiles of circulating tumor DNA detected using CAPP‑Seq in neoadjuvant chemotherapy‑treated advanced ovarian cancer

Tomoko Noguchi, Kazuko Sakai, Naoyuki Iwahashi, Kaho Matsuda, Hitomi Matsukawa, Tamaki Yahata, Saori Toujima, Kazuto Nishio, Kazuhiko Ino
Pages: 2713-2720
Published online on: 28 January 2020

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Article Open Access

lncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial‑to‑mesenchymal transition Retraction in /10.3892/ol.2020.11949

Wenrui Xu, Xiaohan Sun, Chuanshan Zang, Yan Jiang
Pages: 2721-2726
Published online on: 14 February 2020

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Article Open Access

miR‑939‑3p promotes epithelial‑mesenchymal transition and may be used as a prognostic marker in hepatocellular carcinoma

Fei Chen, Xiaoying Ni, Lingxiu Chen, Xiaoyan Wang, Ji Xu
Pages: 2727-2732
Published online on: 30 January 2020

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Article Open Access

Influence of combined epidural anesthesia on cognitive function, inflammation and stress response in elderly liver cancer patients undergoing surgery

Yang Su, Yanan Pu, Zhengnan Zhao, Xianglong Yang
Pages: 2733-2738
Published online on: 14 February 2020

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Article Open Access

Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Li Li, Xiaosong Rao, Zhaohong Wen, Xiaosheng Ding, Xiangyi Wang, Weiran Xu, Chao Meng, Yuting Yi, Yanfang Guan, Yongshen Chen, Jiayin Wang, Liang Jun
Pages: 2739-2748
Published online on: 05 February 2020

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Article Open Access

SMAD3 promotes ELK3 expression following transforming growth factor β‑mediated stimulation of MDA‑MB231 cells

Ji‑Hoon Park, Kyung‑Soon Park
Pages: 2749-2754
Published online on: 06 February 2020

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Article Open Access

Expression of Foxp3 and interleukin‑7 receptor and clinicopathological characteristics of patients with diffuse large B‑cell lymphoma

Yan Zhao, Wen‑Li Cui, Zhi‑Yin Feng, Jing Xue, Abulajiang Gulinaer, Wei Zhang
Pages: 2755-2764
Published online on: 06 February 2020

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Article Open Access

Upregulation of MYBL2 independently predicts a poorer prognosis in patients with clear cell renal cell carcinoma

Shan‑Shan Sun, Yang Fu, Jian‑Yang Lin
Pages: 2765-2772
Published online on: 17 February 2020

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Article Open Access

Ubiquitin‑like modifier‑activating enzyme 7 as a marker for the diagnosis and prognosis of breast cancer

Meng Lin, Yanqing Li, Shanshan Qin, Yan Jiao, Fang Hua
Pages: 2773-2784
Published online on: 17 February 2020

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Article Open Access

Evaluation of kininogen 1, osteopontin and α‑1‑antitrypsin in plasma, bronchoalveolar lavage fluid and urine for lung squamous cell carcinoma diagnosis

Weiwei Wang, Shanshan Wang, Man Zhang
Pages: 2785-2792
Published online on: 06 February 2020

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Article Open Access

Identification of a long non‑coding RNA signature for predicting prognosis and biomarkers in lung adenocarcinoma

Xiaolin Yu, Yanxia Zhang
Pages: 2793-2800
Published online on: 17 February 2020

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Article Open Access

4‑methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight‑hyaluronan in fibrosarcoma cells

Kazuki Hasegawa, Ryo Saga, Rei Takahashi, Roman Fukui, Mitsuru Chiba, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa
Pages: 2801-2808
Published online on: 05 February 2020

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Article Open Access

A novel anti‑EGFR monoclonal antibody (EMab‑17) exerts antitumor activity against oral squamous cell carcinomas via antibody‑dependent cellular cytotoxicity and complement‑dependent cytotoxicity

Junko Takei, Mika Kato Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato
Pages: 2809-2816
Published online on: 10 February 2020

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Article Open Access

Gene expression profiling identified TP53MutPIK3CAWild as a potential biomarker for patients with triple‑negative breast cancer treated with immune checkpoint inhibitors

Jia'nan Cheng, Xiaofang Ding, Shouxia Xu, Bo Zhu, Qingzhu Jia
Pages: 2817-2824
Published online on: 10 February 2020

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Article Open Access

PEBP4 gene expression in lung squamous cell carcinoma: A meta‑analysis‑based study of the molecular pathways involved

Guiping Yu, Ning Zhong, Bin Huang, Yedong Mi
Pages: 2825-2831
Published online on: 12 February 2020

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Article Open Access

LINK‑A lncRNA is upregulated in osteosarcoma and regulates migration, invasion and stemness of osteosarcoma cells

Yao Kong, Zhikui Nie, Hongmin Guo, Cao Ma
Pages: 2832-2838
Published online on: 05 February 2020

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Article Open Access

Knockdown of long non‑coding RNA prostate cancer‑associated transcript 1 inhibits the proliferation and metastasis of tongue squamous cell carcinoma cells by upregulating p21

Ming Yan, Tianjiang Zhao, Lingling Fu, Rongxiang Tian, Dongzhen Li, Yunmeng Da
Pages: 2839-2845
Published online on: 06 February 2020

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Article Open Access

Identification of hub genes associated with outcome of clear cell renal cell carcinoma

Rengui Li, Lei Wang, Xiao Wang, Rong‑Xin Geng, Ning Li, Xiu‑Heng Liu
Pages: 2846-2860
Published online on: 12 February 2020

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Article Open Access

Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes

Li‑Rong Ling, Dan‑Hua Zheng, Zhi‑Yang Zhang, Wen‑Hui Xie, Yue‑Hong Huang, Zhi‑Xin Chen, Xiao‑Zhong Wang, Dan Li
Pages: 2861-2869
Published online on: 17 February 2020

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Article Open Access

GEM on proliferation and apoptosis of childhood AL cells through inhibiting c‑myc expression by upregulating miR‑125a‑3p

Weiwei Xing, Yuxia Yin, Saina Yang, Guang Lu
Pages: 2870-2874
Published online on: 14 February 2020

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Article Open Access

C‑C motif chemokine 14 as a novel potential biomarker for predicting the prognosis of epithelial ovarian cancer

Yubo Cai, Yihong Ling, Lingbo Huang, Hui Huang, Xianlan Chen, Yongbo Xiao, Zhongmei Zhu, Jiewei Chen
Pages: 2875-2883
Published online on: 07 February 2020

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Article Open Access

De novo metastatic breast cancer: Subgroup analysis of molecular subtypes and prognosis

Li Zhang, Zhijun Li, Jie Zhang, Yansheng Wu, Yuying Zhu, Zhongsheng Tong
Pages: 2884-2894
Published online on: 30 January 2020

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Article Open Access

RBBP6 induces non‑small cell lung cancer cell proliferation and high expression is associated with poor prognosis

Qiu‑Shi Wang, Shi‑Rong Wei, Hua‑Liang Xiao
Pages: 2895-2901
Published online on: 17 February 2020

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Article Open Access

MicroRNA‑212 suppresses cell proliferation in nasopharyngeal carcinoma by targeting ELF3

Yaojie Kang, Yanfei Cui, Ming Tan
Pages: 2902-2908
Published online on: 17 February 2020

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Article Open Access

Effects of CDK6 regulated by miR‑298 on proliferation and apoptosis of thyroid cancer cells

Xinyan Li, Cuicui Liu, Xiumei Zhao, Rui Wang, Na Gu, Hongsheng Shen, Xijing Li, Luyao Wang, Chao Li
Pages: 2909-2915
Published online on: 14 February 2020

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Article Open Access

BCL11A confers cell invasion and migration in androgen receptor‑positive triple‑negative breast cancer

Xin Wang, Yumei Xu, Kun Xu, Yajuan Chen, Xiudi Xiao, Xiaoxiang Guan
Pages: 2916-2924
Published online on: 10 February 2020

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Article Open Access

Heavy metals interfere with plasma metabolites, including lipids and amino acids, in patients with breast cancer

Ling Li, Meihua Zhang, Yuhao Men, Wei Wang, Weidong Zhang
Pages: 2925-2933
Published online on: 17 February 2020

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Article Open Access

Intratumoral heterogeneity of glutaminase and lactate dehydrogenase A protein expression in colorectal cancer

Yuta Mizuno, Kimiaki Hattori, Kohei Taniguchi, Keitaro Tanaka, Kazuhisa Uchiyama, Yoshinobu Hirose
Pages: 2934-2942
Published online on: 13 February 2020

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Article Open Access

Timing of changing therapy from gemcitabine and cisplatin chemotherapy based on real‑world data of advanced urothelial carcinoma

Nobuki Furubayashi, Takahito Negishi, Dai Takamatsu, Kosuke Ieiri, Tomohiro Inoue, Keiji Tsukino, Motonobu Nakamura
Pages: 2943-2949
Published online on: 05 February 2020

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Article Open Access

Rapamycin inhibits proliferation and apoptosis of retinoblastoma cells through PI3K/AKT signaling pathway

Jun Yao, Min Xu, Ziyao Liu
Pages: 2950-2956
Published online on: 30 January 2020

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Case Report

Complex karyotype with cryptic FUS gene rearrangement and deletion of NR3C1 and VPREB1 genes in childhood B‑cell acute lymphoblastic leukemia: A case report

Moneeb A.K. Othman, Marina Đurišić, Gordana Samardzija, Dragana Vujić, Nina Lakic, Zeljko Zecevic, Fawaz Al‑Shaheri, Rouben Aroutiounian, Joana B. Melo, Isabel M. Carreira, Britta Meyer, Thomas Liehr
Pages: 2957-2962
Published online on: 12 February 2020

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Article

Pristimerin inhibits the proliferation of HT1080 fibrosarcoma cells by inducing apoptosis

Daichi Hayashi, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Yuji Arai, Osam Mazda, Toshikazu Kubo
Pages: 2963-2970
Published online on: 17 February 2020

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Article

Comprehensive circular RNA profiling reveals the regulatory role of circ_100242/miR-145 pathway in bladder cancer

Zhaowei Zhu, Fujiang Chang, Junxiao Liu, Jiange Wang, Xuepei Zhang
Pages: 2971-2978
Published online on: 10 February 2020

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Article

Development of a nine‑lncRNA signature as a novel prognostic marker of estrogen receptor‑negative breast cancer

Zhiwei Wang, Jie Wang, Lei Liu, Qi He, Min Wei
Pages: 2979-2988
Published online on: 13 February 2020

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Article

NOS1 expression promotes proliferation and invasion and enhances chemoresistance in ovarian cancer

Zhiwei Zou, Xiaoxuan Li, Yongliang Sun, Linlin Li, Qianbing Zhang, Lingqun Zhu, Zhuo Zhong, Meng Wang, Qianli Wang, Zhenjun Liu, Yifeng Wang, Yifang Ping, Kaitai Yao, Bingtao Hao, Qiuzhen Liu
Pages: 2989-2995
Published online on: 27 January 2020

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Article

Determination of the optimal detection time of circulating tumor cells for the postoperative monitoring of colorectal cancer

Tianchen Huang, Cheng Xu, Jianan Xiao, Qingbing Wang, Yanjun Wang, Yong Zhang, Dongxiao Bai, Fuyou Zhou, Xiaoyu Zhao
Pages: 2996-3002
Published online on: 12 February 2020

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Article

Methylation profiling in promoter sequences of ATM and CDKN2A (p14ARF/p16INK4a) genes in blood and cfDNA from women with impalpable breast lesions

Lucas Delmonico, Mauricio Augusto Silva Magalhães Costa, Romario José Gomes, Pâmella de Oliveira Vieira, Ana Beatriz Passos da Silva, Marcia V. Fournier, Luciano Rios Scherrer, Carolina Maria de Azevedo, Maria Helena Faria Ornellas, Gilda Alves
Pages: 3003-3010
Published online on: 10 February 2020

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Article

Serum melatonin is inversely associated with matrix metalloproteinase‑9 in oral squamous cell carcinoma

Adina Elena Stanciu, Adina Zamfir‑Chiru‑Anton, Marcel Marian Stanciu, Anca Pantea‑Stoian, Cornelia Nitipir, Dan Cristian Gheorghe
Pages: 3011-3020
Published online on: 13 February 2020

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Article

Potential synergistic effects of sorafenib and CP‑31398 for treating anaplastic thyroid cancer with p53 mutations

Jiin‑Torng Wu, Ching‑Ling Lin, Chi‑Jung Huang, Yu‑Che Cheng, Chih‑Cheng Chien, Yung‑Chuan Sung
Pages: 3021-3026
Published online on: 07 February 2020

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Article

Sasa quelpaertensis Nakai extract induces p53‑independent apoptosis via the elevation of nitric oxide production in human HCT116 colon cancer cells

Min Young Kim
Pages: 3027-3034
Published online on: 10 February 2020

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Correction Open Access

[Erratum] Peripheral primitive neuroectodermal tumors: A retrospective analysis of 89 cases and literature review

Liming Gao, Yingying Zhu, Xiaohua Shi, Zhiqiang Gao, Xingming Chen
Pages: 3035-3035
Published online on: 12 February 2020

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Review Open Access

Association of oral dysbiosis with oral cancer development (Review)

Giusy Rita Maria La Rosa, Giuseppe Gattuso, Eugenio Pedullà, Ernesto Rapisarda, Daria Nicolosi, Mario Salmeri
Pages: 3045-3058
Published online on: 03 March 2020

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Review Open Access

The roles of curcumin in regulating the tumor immunosuppressive microenvironment (Review)

Yizhi Wang, Jun Lu, Bolun Jiang, Junchao Guo
Pages: 3059-3070
Published online on: 03 March 2020

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Article Open Access

Long non‑coding RNA BRM promotes proliferation and invasion of papillary thyroid carcinoma by regulating the microRNA‑331‑3p/SLC25A1 axis

Shihong Liu, Deping Zhang, Li Chen, Shangfang Gao, Xiu Huang
Pages: 3071-3078
Published online on: 20 February 2020

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Article Open Access

microRNA‑144 inhibits cell proliferation and invasion by directly targeting TIGAR in esophageal carcinoma

Yushu Mu, Qifei Wang, Lei Tan, Lin Lin, Benhua Zhang
Pages: 3079-3088
Published online on: 24 February 2020

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Texture analysis of early cerebral tissue damage in magnetic resonance imaging of patients with lung cancer

Jiying Xu, Xiaoxiao Cui, Bomin Wang, Guangyu Wang, Meng Han, Ranran Li, Yana Qi, Jianjun Xiu, Qianlong Yang, Zhi Liu, Mingyong Han
Pages: 3089-3100
Published online on: 03 March 2020

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Comprehensive genomic profile of cholangiocarcinomas in China

Weijun Tian, Weiyu Hu, Xiaoling Shi, Peng Liu, Xiang Ma, Wei Zhao, Linlin Qu, Shuirong Zhang, Weiwei Shi, Angen Liu, Jingyu Cao
Pages: 3101-3110
Published online on: 03 March 2020

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Increased expression of the RNA‑binding motif protein 47 predicts poor prognosis in non‑small‑cell lung cancer

Ruilei Li, Heng Li, Chunlei Ge, Qiaofen Fu, Zhen Li, Yarong Jin, Qinghua Tan, Zhitao Zhu, Zhiwei Zhang, Suwei Dong, Gaofeng Li, Xin Song
Pages: 3111-3122
Published online on: 20 February 2020

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Integrated analysis of transcriptome profiling predicts potential lncRNA and circRNA targets in human nasopharyngeal carcinoma

Dong‑Ni Zhou, Chun‑Sheng Ye, Qing‑Qing Yang, Yan‑Fei Deng
Pages: 3123-3136
Published online on: 19 February 2020

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Article Open Access

Multidisciplinary treatment system for bone metastases for early diagnosis, treatment and prevention of malignant spinal cord compression

Eiji Nakata, Shinsuke Sugihara, Yoshifumi Sugawara, Ryuichi Nakahara, Takayuki Furumatsu, Tomonori Tetsunaga, Toshiyuki Kunisada, Kazuo Nakanishi, Yoshiteru Akezaki, Toshifumi Ozaki
Pages: 3137-3144
Published online on: 20 February 2020

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CEP131 knockdown inhibits cell proliferation by inhibiting the ERK and AKT signaling pathways in non‑small cell lung cancer

Junying Wang, Xiaoping Yang, Shixin Han, Lizhi Zhang
Pages: 3145-3152
Published online on: 19 February 2020

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Article Open Access

Differential behavior of NF‑κB, IκBα and EGFR during the renal carcinogenic process in an experimental model in vivo

Telma Pariente‑Pérez, Francisco Aguilar‑Alonso, José Dolores Solano, Chabetty Vargas‑Olvera, Patricia Curiel‑Muñiz, Carmen Adriana Mendoza‑Rodríguez, Daniela Tenorio‑Hernández, María Elena Ibarra‑Rubio
Pages: 3153-3164
Published online on: 03 March 2020

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Article Open Access

Paeoniflorin inhibits cell viability and invasion of liver cancer cells via inhibition of Skp2

Hong Liu, Lili Zang, Jun Zhao, Zhaolin Wang, Lingyun Li
Pages: 3165-3172
Published online on: 03 March 2020

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MicroRNA‑132‑3p regulates cell proliferation, apoptosis, migration and invasion of liver cancer by targeting Sox4

Jiansheng Huang, Dudan Lu, Tianxin Xiang, Xiaoping Wu, Shanfei Ge, Yue Wang, Jiaxin Wang, Na Cheng
Pages: 3173-3180
Published online on: 03 March 2020

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High expression of FOXO3 is associated with poor prognosis in patients with hepatocellular carcinoma

Shu‑Shu Song, Jia‑Fu Ying, You‑Ni Zhang, Hong‑Ying Pan, Xiang‑Lei He, Zhi‑Ming Hu, Hui‑Ju Wang, Xiao‑Bing Dou, Xiao‑Zhou Mou
Pages: 3181-3188
Published online on: 03 March 2020

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Article Open Access

Enolase 1 differentially contributes to cell transformation in lung cancer but not in esophageal cancer

Jo‑Mei Maureen Chen, Shao‑Chih Chiu, Kun‑Chieh Chen, Yun‑Ru Jaoying Huang, Yu‑Ting Amber Liao, Chang‑Tze Ricky Yu
Pages: 3189-3196
Published online on: 03 March 2020

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METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway

Shumei Liang, Hongwei Guan, Xiaoyan Lin, Na Li, Feng Geng, Juan Li
Pages: 3197-3204
Published online on: 03 March 2020

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Article Open Access

APOBEC3B expression and its prognostic potential in breast cancer

Yan Mao, Meng Lv, Yuzi Zhang, Gang Nie, Jian Cui, Yongmei Wang, Yuanyuan Wang, Weihong Cao, Xiaoyi Liu, Xingang Wang, Haibo Wang
Pages: 3205-3214
Published online on: 03 March 2020

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Article Open Access

Advanced glycation end products induce proliferation, invasion and epithelial‑mesenchymal transition of human SW480 colon cancer cells through the PI3K/AKT signaling pathway

Huasheng Liang
Pages: 3215-3222
Published online on: 19 February 2020

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Article Open Access

Hematoporphyrin monomethyl ether‑mediated sonodynamic therapy induces A‑253 cell apoptosis

Yi Zhang, Liangjia Bi, Zheng Hu, Wenwu Cao, Deshu Zhuang
Pages: 3223-3228
Published online on: 21 February 2020

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Article Open Access

Methylated PTGER4 is better than CA125, CEA, Cyfra211 and NSE as a therapeutic response assessment marker in stage IV lung cancer

Yunxia Zhang, Jianfeng Huang, Qinzhou Zou, Jun Che, Kaihua Yang, Qiang Fan, Danqi Qian, Jia Wu, Erwen Bao, Lele Song, Fuzheng Zhang
Pages: 3229-3238
Published online on: 03 March 2020

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Article Open Access

miR‑320/ELF3 axis inhibits the progression of breast cancer via the PI3K/AKT pathway

Zhiqiang Zhang, Jinku Zhang, Jinmei Li, Huijuan Geng, Bingjuan Zhou, Bingxin Zhang, Hong Chen
Pages: 3239-3248
Published online on: 03 March 2020

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Article Open Access

Early risk warning system for distant metastasis of hepatitis B virus‑associated hepatocellular carcinoma with portal vein tumor thrombus

Mengge Li, Yalin Zhao, Xiaoli Liu, Shuan Zhang, Yuyong Jiang, Zhiyun Yang
Pages: 3249-3257
Published online on: 03 March 2020

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Cell proliferation is induced in renal cell carcinoma through miR‑92a‑3p upregulation by targeting FBXW7

Rong Zeng, Jing Huang, Yujie Sun, Juan Luo
Pages: 3258-3268
Published online on: 03 March 2020

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Autophagy suppresses resveratrol‑induced apoptosis in renal cell carcinoma 786‑O cells

Hongwei Yao, Min Fan, Xiaozhou He
Pages: 3269-3277
Published online on: 03 March 2020

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Associations of sirtuins with clinicopathological variables and prognosis in human ovarian cancer

Qikuan He, Kai Chen, Ruifan Ye, Ninggao Dai, Pengyi Guo, Leixi Wang
Pages: 3278-3288
Published online on: 03 March 2020

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MicroRNA‑21 promotes cell metastasis in cervical cancer through modulating epithelial‑mesenchymal transition

Yaling Tang, Yan Zhao, Jing Ran, Yifeng Wang
Pages: 3289-3295
Published online on: 03 March 2020

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Profiles of m6A RNA methylation regulators for the prognosis of hepatocellular carcinoma

Wang Li, Qi‑Feng Chen, Tao Huang, Lujun Shen, Zi‑Lin Huang, Peihong Wu
Pages: 3296-3306
Published online on: 03 March 2020

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Upregulation of ASPM, BUB1B and SPDL1 in tumor tissues predicts poor survival in patients with pancreatic ductal adenocarcinoma

Xiong Tian, Na Wang
Pages: 3307-3315
Published online on: 19 February 2020

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Comprehensive gene and pathway analysis of cervical cancer progression

Yuexiong Yi, Yan Fang, Kejia Wu, Yanyan Liu, Wei Zhang
Pages: 3316-3332
Published online on: 03 March 2020

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Article

Semaphorin‑4C is upregulated in epithelial ovarian cancer

Shaoyan Huang, Shan Han, Jianzhong Zhang, Zhaokun Zhong, Jianrong Wang
Pages: 3333-3338
Published online on: 03 March 2020

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Article

Downregulation of TMOD1 promotes cell motility and cell proliferation in cervical cancer cells

Fangjin Lu, Dandan Cui, Bin Mu, Lu Zhao, Ping Mu
Pages: 3339-3348
Published online on: 19 February 2020

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Article

RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signaling

Sujing Zhuang, Li Li, Yuwei Zang, Guangfeng Li, Feng Wang
Pages: 3349-3355
Published online on: 03 March 2020

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Correction Open Access

[Corrigendum] Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3356-3356
Published online on: 18 February 2020

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Correction Open Access

[Corrigendum] MicroRNA‑152 suppresses cisplatin resistance in A549 cells

Wenfei Zhao, Hongyun Li, Shanshan Yang, Di Guo, Jing Chen, Shaoyi Miao, Yi Xin, Miaomiao Liang
Pages: 3357-3357
Published online on: 28 February 2020

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Correction Open Access

[Corrigendum] P130cas is required for TGF‑β1‑mediated epithelial‑mesenchymal transition in lung cancer

Bo Deng, Qun‑You Tan, Ru‑Wen Wang, Yao‑Guang Jiang, Jing‑Hai Zhou, Wei Huang
Pages: 3358-3358
Published online on: 20 February 2020

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Correction Open Access

[Corrigendum] Loss of E‑cadherin promotes prostate cancer metastasis via upregulation of metastasis‑associated gene 1 expression

Liangsheng Fan, Hongyan Wang, Xi Xia, Yumei Rao, Xiangyi Ma, Ding Ma, Peng Wu, Gang Chen
Pages: 3359-3359
Published online on: 28 February 2020

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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