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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2020 Volume 19 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Overview of the STAT‑3 signaling pathway in cancer and the development of specific inhibitors (Review)

Yuchen Gu, Imran Shair Mohammad, Zhe Liu
Pages: 2585-2594
Published online on: 13 February 2020

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Review Open Access

Role and mechanism of programmed death‑ligand 1 in hypoxia‑induced liver cancer immune escape (Review)

Qingxian Wen, Tao Han, Zijian Wang, Shulong Jiang
Pages: 2595-2601
Published online on: 05 February 2020

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Article Open Access

Podoplanin is an efficient predictor of neck lymph node metastasis in tongue squamous cell carcinoma with low tumor budding grade

Mei Hamada, Yasuhiro Ebihara, Koji Nagata, Mitsutake Yano, Yasunao Kogashiwa, Mitsuhiko Nakahira, Masashi Sugasawa, Hitoshi Nagatsuka, Masanori Yasuda
Pages: 2602-2608
Published online on: 29 January 2020

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Article Open Access

Association between G‑protein coupled receptor 4 expression and microvessel density, clinicopathological characteristics and survival in hepatocellular carcinoma

Chaofan Xue, Shuai Shao, Yanli Yan, Si Yang, Shuheng Bai, Yinying Wu, Jiangzhou Zhang, Rui Liu, Hailin Ma, Linyan Chai, Xiaozhi Zhang, Juan Ren
Pages: 2609-2620
Published online on: 05 February 2020

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Article Open Access

Maspin inhibits MCF‑7 cell invasion and proliferation by downregulating miR‑21 and increasing the expression of its target genes

Shao‑Xin Huang, Wen‑Yan Fan, Ling Wang, Hui Liu, Xin Wang, Hao Zhao, Wen‑Bin Jiang
Pages: 2621-2628
Published online on: 30 January 2020

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Article Open Access

Pharmacological ascorbate induces ‘BRCAness’ and enhances the effects of Poly(ADP‑Ribose) polymerase inhibitors against BRCA1/2 wild‑type ovarian cancer

Yan Ma, Ping Chen, Jeanne A. Drisko, Dineo Khabele, Andrew K. Godwin, Qi Chen
Pages: 2629-2638
Published online on: 31 January 2020

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Article Open Access

Decreased IL‑37 expression in hepatocellular carcinoma tissues and liver cancer cell lines

Peng Li, Hongsheng Guo, Kun Wu, Liudan Su, Kai Huang, Ruizhi Lai, Ziliang Deng, Shuxian Li, Ping Ouyang, Yan Wang, Zhangquan Chen, Guangji Zhou, Sen Wang
Pages: 2639-2648
Published online on: 13 February 2020

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Article Open Access

Interferon‑β sensitizes human glioblastoma cells to the cyclin‑dependent kinase inhibitor, TG02

Birthe Lohmann, Emilie Le Rhun, Manuela Silginer, Mirka Epskamp, Michael Weller
Pages: 2649-2656
Published online on: 30 January 2020

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Article Open Access

Usefulness of plasma full‑length glypican‑3 as a predictive marker of hepatocellular carcinoma recurrence after radial surgery

Masahiro Miura, Norihiro Fujinami, Yasuhiro Shimizu, Shoichi Mizuno, Keigo Saito, Toshihiro Suzuki, Masaru Konishi, Shinichiro Takahashi, Naoto Gotohda, Kouzou Suto, Tomokazu Yoshida, Tetsuya Nakatsura
Pages: 2657-2666
Published online on: 05 February 2020

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Article Open Access

Indication of suitable transarterial chemoembolization and multikinase inhibitors for intermediate stage hepatocellular carcinoma

Shigeo Shimose, Takumi Kawaguchi, Hideki Iwamoto, Takashi Niizeki, Tomotake Shirono, Masatoshi Tanaka, Hironori Koga, Takuji Torimura
Pages: 2667-2676
Published online on: 17 February 2020

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Article Open Access

miR‑3940‑5p/miR‑8069 ratio in urine exosomes is a novel diagnostic biomarker for pancreatic ductal adenocarcinoma

Naohiko Yoshizawa, Kazushi Sugimoto, Masahiko Tameda, Yuji Inagaki, Makoto Ikejiri, Hiroyuki Inoue, Masanobu Usui, Masaaki Ito, Yoshiyuki Takei
Pages: 2677-2684
Published online on: 29 January 2020

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Article Open Access

Upregulation of microRNA‑31 is associated with poor prognosis in patients with advanced colorectal cancer

Nobuhito Kubota, Fumitaka Taniguchi, Akihiro Nyuya, Yuzo Umeda, Yoshiko Mori, Toshiyoshi Fujiwara, Hiroaki Tanioka, Atsushi Tsuruta, Yoshiyuki Yamaguchi, Takeshi Nagasaka
Pages: 2685-2694
Published online on: 03 February 2020

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Article Open Access

Salvage stereotactic body radiotherapy for post‑operative oligo‑recurrence of non‑small cell lung cancer: A single‑institution analysis of 59 patients

Shuri Aoki, Hideomi Yamashita, Wataru Takahashi, Kanabu Nawa, Takeshi Ota, Toshikazu Imae, Sho Ozaki, Yuki Nozawa, Jun Nakajima, Masaaki Sato, Masaki Anraku, Junichi Nitadori, Takahiro Karasaki, Osamu Abe, Keiichi Nakagawa
Pages: 2695-2704
Published online on: 17 February 2020

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Article Open Access

The pathological complete response and secreted protein acidic and rich in cysteine expression in patients with breast cancer receiving neoadjuvant nab‑paclitaxel chemotherapy

Yuko Nakazawa, Seshiru Nakazawa, Sasagu Kurozumi, Misato Ogino, Yukio Koibuchi, Hiroki Odawara, Tetsunari Oyama, Jun Horiguchi, Takaaki Fujii, Ken Shirabe
Pages: 2705-2712
Published online on: 27 January 2020

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Article Open Access

Changes in the gene mutation profiles of circulating tumor DNA detected using CAPP‑Seq in neoadjuvant chemotherapy‑treated advanced ovarian cancer

Tomoko Noguchi, Kazuko Sakai, Naoyuki Iwahashi, Kaho Matsuda, Hitomi Matsukawa, Tamaki Yahata, Saori Toujima, Kazuto Nishio, Kazuhiko Ino
Pages: 2713-2720
Published online on: 28 January 2020

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Article Open Access

lncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial‑to‑mesenchymal transition Retraction in /10.3892/ol.2020.11949

Wenrui Xu, Xiaohan Sun, Chuanshan Zang, Yan Jiang
Pages: 2721-2726
Published online on: 14 February 2020

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Article Open Access

miR‑939‑3p promotes epithelial‑mesenchymal transition and may be used as a prognostic marker in hepatocellular carcinoma

Fei Chen, Xiaoying Ni, Lingxiu Chen, Xiaoyan Wang, Ji Xu
Pages: 2727-2732
Published online on: 30 January 2020

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Article Open Access

Influence of combined epidural anesthesia on cognitive function, inflammation and stress response in elderly liver cancer patients undergoing surgery

Yang Su, Yanan Pu, Zhengnan Zhao, Xianglong Yang
Pages: 2733-2738
Published online on: 14 February 2020

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Article Open Access

Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Li Li, Xiaosong Rao, Zhaohong Wen, Xiaosheng Ding, Xiangyi Wang, Weiran Xu, Chao Meng, Yuting Yi, Yanfang Guan, Yongshen Chen, Jiayin Wang, Liang Jun
Pages: 2739-2748
Published online on: 05 February 2020

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Article Open Access

SMAD3 promotes ELK3 expression following transforming growth factor β‑mediated stimulation of MDA‑MB231 cells

Ji‑Hoon Park, Kyung‑Soon Park
Pages: 2749-2754
Published online on: 06 February 2020

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Article Open Access

Expression of Foxp3 and interleukin‑7 receptor and clinicopathological characteristics of patients with diffuse large B‑cell lymphoma

Yan Zhao, Wen‑Li Cui, Zhi‑Yin Feng, Jing Xue, Abulajiang Gulinaer, Wei Zhang
Pages: 2755-2764
Published online on: 06 February 2020

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Article Open Access

Upregulation of MYBL2 independently predicts a poorer prognosis in patients with clear cell renal cell carcinoma

Shan‑Shan Sun, Yang Fu, Jian‑Yang Lin
Pages: 2765-2772
Published online on: 17 February 2020

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Article Open Access

Ubiquitin‑like modifier‑activating enzyme 7 as a marker for the diagnosis and prognosis of breast cancer

Meng Lin, Yanqing Li, Shanshan Qin, Yan Jiao, Fang Hua
Pages: 2773-2784
Published online on: 17 February 2020

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Article Open Access

Evaluation of kininogen 1, osteopontin and α‑1‑antitrypsin in plasma, bronchoalveolar lavage fluid and urine for lung squamous cell carcinoma diagnosis

Weiwei Wang, Shanshan Wang, Man Zhang
Pages: 2785-2792
Published online on: 06 February 2020

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Article Open Access

Identification of a long non‑coding RNA signature for predicting prognosis and biomarkers in lung adenocarcinoma

Xiaolin Yu, Yanxia Zhang
Pages: 2793-2800
Published online on: 17 February 2020

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Article Open Access

4‑methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight‑hyaluronan in fibrosarcoma cells

Kazuki Hasegawa, Ryo Saga, Rei Takahashi, Roman Fukui, Mitsuru Chiba, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa
Pages: 2801-2808
Published online on: 05 February 2020

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Article Open Access

A novel anti‑EGFR monoclonal antibody (EMab‑17) exerts antitumor activity against oral squamous cell carcinomas via antibody‑dependent cellular cytotoxicity and complement‑dependent cytotoxicity

Junko Takei, Mika Kato Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato
Pages: 2809-2816
Published online on: 10 February 2020

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Article Open Access

Gene expression profiling identified TP53MutPIK3CAWild as a potential biomarker for patients with triple‑negative breast cancer treated with immune checkpoint inhibitors

Jia'nan Cheng, Xiaofang Ding, Shouxia Xu, Bo Zhu, Qingzhu Jia
Pages: 2817-2824
Published online on: 10 February 2020

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Article Open Access

PEBP4 gene expression in lung squamous cell carcinoma: A meta‑analysis‑based study of the molecular pathways involved

Guiping Yu, Ning Zhong, Bin Huang, Yedong Mi
Pages: 2825-2831
Published online on: 12 February 2020

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Article Open Access

LINK‑A lncRNA is upregulated in osteosarcoma and regulates migration, invasion and stemness of osteosarcoma cells

Yao Kong, Zhikui Nie, Hongmin Guo, Cao Ma
Pages: 2832-2838
Published online on: 05 February 2020

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Article Open Access

Knockdown of long non‑coding RNA prostate cancer‑associated transcript 1 inhibits the proliferation and metastasis of tongue squamous cell carcinoma cells by upregulating p21

Ming Yan, Tianjiang Zhao, Lingling Fu, Rongxiang Tian, Dongzhen Li, Yunmeng Da
Pages: 2839-2845
Published online on: 06 February 2020

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Article Open Access

Identification of hub genes associated with outcome of clear cell renal cell carcinoma

Rengui Li, Lei Wang, Xiao Wang, Rong‑Xin Geng, Ning Li, Xiu‑Heng Liu
Pages: 2846-2860
Published online on: 12 February 2020

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Article Open Access

Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes

Li‑Rong Ling, Dan‑Hua Zheng, Zhi‑Yang Zhang, Wen‑Hui Xie, Yue‑Hong Huang, Zhi‑Xin Chen, Xiao‑Zhong Wang, Dan Li
Pages: 2861-2869
Published online on: 17 February 2020

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Article Open Access

GEM on proliferation and apoptosis of childhood AL cells through inhibiting c‑myc expression by upregulating miR‑125a‑3p

Weiwei Xing, Yuxia Yin, Saina Yang, Guang Lu
Pages: 2870-2874
Published online on: 14 February 2020

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Article Open Access

C‑C motif chemokine 14 as a novel potential biomarker for predicting the prognosis of epithelial ovarian cancer

Yubo Cai, Yihong Ling, Lingbo Huang, Hui Huang, Xianlan Chen, Yongbo Xiao, Zhongmei Zhu, Jiewei Chen
Pages: 2875-2883
Published online on: 07 February 2020

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Article Open Access

De novo metastatic breast cancer: Subgroup analysis of molecular subtypes and prognosis

Li Zhang, Zhijun Li, Jie Zhang, Yansheng Wu, Yuying Zhu, Zhongsheng Tong
Pages: 2884-2894
Published online on: 30 January 2020

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Article Open Access

RBBP6 induces non‑small cell lung cancer cell proliferation and high expression is associated with poor prognosis

Qiu‑Shi Wang, Shi‑Rong Wei, Hua‑Liang Xiao
Pages: 2895-2901
Published online on: 17 February 2020

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Article Open Access

MicroRNA‑212 suppresses cell proliferation in nasopharyngeal carcinoma by targeting ELF3

Yaojie Kang, Yanfei Cui, Ming Tan
Pages: 2902-2908
Published online on: 17 February 2020

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Article Open Access

Effects of CDK6 regulated by miR‑298 on proliferation and apoptosis of thyroid cancer cells

Xinyan Li, Cuicui Liu, Xiumei Zhao, Rui Wang, Na Gu, Hongsheng Shen, Xijing Li, Luyao Wang, Chao Li
Pages: 2909-2915
Published online on: 14 February 2020

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Article Open Access

BCL11A confers cell invasion and migration in androgen receptor‑positive triple‑negative breast cancer

Xin Wang, Yumei Xu, Kun Xu, Yajuan Chen, Xiudi Xiao, Xiaoxiang Guan
Pages: 2916-2924
Published online on: 10 February 2020

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Article Open Access

Heavy metals interfere with plasma metabolites, including lipids and amino acids, in patients with breast cancer

Ling Li, Meihua Zhang, Yuhao Men, Wei Wang, Weidong Zhang
Pages: 2925-2933
Published online on: 17 February 2020

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Article Open Access

Intratumoral heterogeneity of glutaminase and lactate dehydrogenase A protein expression in colorectal cancer

Yuta Mizuno, Kimiaki Hattori, Kohei Taniguchi, Keitaro Tanaka, Kazuhisa Uchiyama, Yoshinobu Hirose
Pages: 2934-2942
Published online on: 13 February 2020

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Article Open Access

Timing of changing therapy from gemcitabine and cisplatin chemotherapy based on real‑world data of advanced urothelial carcinoma

Nobuki Furubayashi, Takahito Negishi, Dai Takamatsu, Kosuke Ieiri, Tomohiro Inoue, Keiji Tsukino, Motonobu Nakamura
Pages: 2943-2949
Published online on: 05 February 2020

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Article Open Access

Rapamycin inhibits proliferation and apoptosis of retinoblastoma cells through PI3K/AKT signaling pathway

Jun Yao, Min Xu, Ziyao Liu
Pages: 2950-2956
Published online on: 30 January 2020

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Case Report

Complex karyotype with cryptic FUS gene rearrangement and deletion of NR3C1 and VPREB1 genes in childhood B‑cell acute lymphoblastic leukemia: A case report

Moneeb A.K. Othman, Marina Đurišić, Gordana Samardzija, Dragana Vujić, Nina Lakic, Zeljko Zecevic, Fawaz Al‑Shaheri, Rouben Aroutiounian, Joana B. Melo, Isabel M. Carreira, Britta Meyer, Thomas Liehr
Pages: 2957-2962
Published online on: 12 February 2020

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Article

Pristimerin inhibits the proliferation of HT1080 fibrosarcoma cells by inducing apoptosis

Daichi Hayashi, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Yuji Arai, Osam Mazda, Toshikazu Kubo
Pages: 2963-2970
Published online on: 17 February 2020

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Article

Comprehensive circular RNA profiling reveals the regulatory role of circ_100242/miR-145 pathway in bladder cancer

Zhaowei Zhu, Fujiang Chang, Junxiao Liu, Jiange Wang, Xuepei Zhang
Pages: 2971-2978
Published online on: 10 February 2020

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Article

Development of a nine‑lncRNA signature as a novel prognostic marker of estrogen receptor‑negative breast cancer

Zhiwei Wang, Jie Wang, Lei Liu, Qi He, Min Wei
Pages: 2979-2988
Published online on: 13 February 2020

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Article

NOS1 expression promotes proliferation and invasion and enhances chemoresistance in ovarian cancer

Zhiwei Zou, Xiaoxuan Li, Yongliang Sun, Linlin Li, Qianbing Zhang, Lingqun Zhu, Zhuo Zhong, Meng Wang, Qianli Wang, Zhenjun Liu, Yifeng Wang, Yifang Ping, Kaitai Yao, Bingtao Hao, Qiuzhen Liu
Pages: 2989-2995
Published online on: 27 January 2020

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Article

Determination of the optimal detection time of circulating tumor cells for the postoperative monitoring of colorectal cancer

Tianchen Huang, Cheng Xu, Jianan Xiao, Qingbing Wang, Yanjun Wang, Yong Zhang, Dongxiao Bai, Fuyou Zhou, Xiaoyu Zhao
Pages: 2996-3002
Published online on: 12 February 2020

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Article

Methylation profiling in promoter sequences of ATM and CDKN2A (p14ARF/p16INK4a) genes in blood and cfDNA from women with impalpable breast lesions

Lucas Delmonico, Mauricio Augusto Silva Magalhães Costa, Romario José Gomes, Pâmella de Oliveira Vieira, Ana Beatriz Passos da Silva, Marcia V. Fournier, Luciano Rios Scherrer, Carolina Maria de Azevedo, Maria Helena Faria Ornellas, Gilda Alves
Pages: 3003-3010
Published online on: 10 February 2020

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Article

Serum melatonin is inversely associated with matrix metalloproteinase‑9 in oral squamous cell carcinoma

Adina Elena Stanciu, Adina Zamfir‑Chiru‑Anton, Marcel Marian Stanciu, Anca Pantea‑Stoian, Cornelia Nitipir, Dan Cristian Gheorghe
Pages: 3011-3020
Published online on: 13 February 2020

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Article

Potential synergistic effects of sorafenib and CP‑31398 for treating anaplastic thyroid cancer with p53 mutations

Jiin‑Torng Wu, Ching‑Ling Lin, Chi‑Jung Huang, Yu‑Che Cheng, Chih‑Cheng Chien, Yung‑Chuan Sung
Pages: 3021-3026
Published online on: 07 February 2020

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Article

Sasa quelpaertensis Nakai extract induces p53‑independent apoptosis via the elevation of nitric oxide production in human HCT116 colon cancer cells

Min Young Kim
Pages: 3027-3034
Published online on: 10 February 2020

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Correction Open Access

[Erratum] Peripheral primitive neuroectodermal tumors: A retrospective analysis of 89 cases and literature review

Liming Gao, Yingying Zhu, Xiaohua Shi, Zhiqiang Gao, Xingming Chen
Pages: 3035-3035
Published online on: 12 February 2020

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Review Open Access

Association of oral dysbiosis with oral cancer development (Review)

Giusy Rita Maria La Rosa, Giuseppe Gattuso, Eugenio Pedullà, Ernesto Rapisarda, Daria Nicolosi, Mario Salmeri
Pages: 3045-3058
Published online on: 03 March 2020

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Review Open Access

The roles of curcumin in regulating the tumor immunosuppressive microenvironment (Review)

Yizhi Wang, Jun Lu, Bolun Jiang, Junchao Guo
Pages: 3059-3070
Published online on: 03 March 2020

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Article Open Access

Long non‑coding RNA BRM promotes proliferation and invasion of papillary thyroid carcinoma by regulating the microRNA‑331‑3p/SLC25A1 axis

Shihong Liu, Deping Zhang, Li Chen, Shangfang Gao, Xiu Huang
Pages: 3071-3078
Published online on: 20 February 2020

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Article Open Access

microRNA‑144 inhibits cell proliferation and invasion by directly targeting TIGAR in esophageal carcinoma

Yushu Mu, Qifei Wang, Lei Tan, Lin Lin, Benhua Zhang
Pages: 3079-3088
Published online on: 24 February 2020

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Texture analysis of early cerebral tissue damage in magnetic resonance imaging of patients with lung cancer

Jiying Xu, Xiaoxiao Cui, Bomin Wang, Guangyu Wang, Meng Han, Ranran Li, Yana Qi, Jianjun Xiu, Qianlong Yang, Zhi Liu, Mingyong Han
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Comprehensive genomic profile of cholangiocarcinomas in China

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Increased expression of the RNA‑binding motif protein 47 predicts poor prognosis in non‑small‑cell lung cancer

Ruilei Li, Heng Li, Chunlei Ge, Qiaofen Fu, Zhen Li, Yarong Jin, Qinghua Tan, Zhitao Zhu, Zhiwei Zhang, Suwei Dong, Gaofeng Li, Xin Song
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Integrated analysis of transcriptome profiling predicts potential lncRNA and circRNA targets in human nasopharyngeal carcinoma

Dong‑Ni Zhou, Chun‑Sheng Ye, Qing‑Qing Yang, Yan‑Fei Deng
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Published online on: 19 February 2020

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Multidisciplinary treatment system for bone metastases for early diagnosis, treatment and prevention of malignant spinal cord compression

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CEP131 knockdown inhibits cell proliferation by inhibiting the ERK and AKT signaling pathways in non‑small cell lung cancer

Junying Wang, Xiaoping Yang, Shixin Han, Lizhi Zhang
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Differential behavior of NF‑κB, IκBα and EGFR during the renal carcinogenic process in an experimental model in vivo

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Paeoniflorin inhibits cell viability and invasion of liver cancer cells via inhibition of Skp2

Hong Liu, Lili Zang, Jun Zhao, Zhaolin Wang, Lingyun Li
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MicroRNA‑132‑3p regulates cell proliferation, apoptosis, migration and invasion of liver cancer by targeting Sox4

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Enolase 1 differentially contributes to cell transformation in lung cancer but not in esophageal cancer

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METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway

Shumei Liang, Hongwei Guan, Xiaoyan Lin, Na Li, Feng Geng, Juan Li
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APOBEC3B expression and its prognostic potential in breast cancer

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Advanced glycation end products induce proliferation, invasion and epithelial‑mesenchymal transition of human SW480 colon cancer cells through the PI3K/AKT signaling pathway

Huasheng Liang
Pages: 3215-3222
Published online on: 19 February 2020

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Hematoporphyrin monomethyl ether‑mediated sonodynamic therapy induces A‑253 cell apoptosis

Yi Zhang, Liangjia Bi, Zheng Hu, Wenwu Cao, Deshu Zhuang
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Methylated PTGER4 is better than CA125, CEA, Cyfra211 and NSE as a therapeutic response assessment marker in stage IV lung cancer

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miR‑320/ELF3 axis inhibits the progression of breast cancer via the PI3K/AKT pathway

Zhiqiang Zhang, Jinku Zhang, Jinmei Li, Huijuan Geng, Bingjuan Zhou, Bingxin Zhang, Hong Chen
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Early risk warning system for distant metastasis of hepatitis B virus‑associated hepatocellular carcinoma with portal vein tumor thrombus

Mengge Li, Yalin Zhao, Xiaoli Liu, Shuan Zhang, Yuyong Jiang, Zhiyun Yang
Pages: 3249-3257
Published online on: 03 March 2020

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Cell proliferation is induced in renal cell carcinoma through miR‑92a‑3p upregulation by targeting FBXW7

Rong Zeng, Jing Huang, Yujie Sun, Juan Luo
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Published online on: 03 March 2020

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Autophagy suppresses resveratrol‑induced apoptosis in renal cell carcinoma 786‑O cells

Hongwei Yao, Min Fan, Xiaozhou He
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Published online on: 03 March 2020

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Associations of sirtuins with clinicopathological variables and prognosis in human ovarian cancer

Qikuan He, Kai Chen, Ruifan Ye, Ninggao Dai, Pengyi Guo, Leixi Wang
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MicroRNA‑21 promotes cell metastasis in cervical cancer through modulating epithelial‑mesenchymal transition

Yaling Tang, Yan Zhao, Jing Ran, Yifeng Wang
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Published online on: 03 March 2020

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Profiles of m6A RNA methylation regulators for the prognosis of hepatocellular carcinoma

Wang Li, Qi‑Feng Chen, Tao Huang, Lujun Shen, Zi‑Lin Huang, Peihong Wu
Pages: 3296-3306
Published online on: 03 March 2020

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Upregulation of ASPM, BUB1B and SPDL1 in tumor tissues predicts poor survival in patients with pancreatic ductal adenocarcinoma

Xiong Tian, Na Wang
Pages: 3307-3315
Published online on: 19 February 2020

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Comprehensive gene and pathway analysis of cervical cancer progression

Yuexiong Yi, Yan Fang, Kejia Wu, Yanyan Liu, Wei Zhang
Pages: 3316-3332
Published online on: 03 March 2020

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Article

Semaphorin‑4C is upregulated in epithelial ovarian cancer

Shaoyan Huang, Shan Han, Jianzhong Zhang, Zhaokun Zhong, Jianrong Wang
Pages: 3333-3338
Published online on: 03 March 2020

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Downregulation of TMOD1 promotes cell motility and cell proliferation in cervical cancer cells

Fangjin Lu, Dandan Cui, Bin Mu, Lu Zhao, Ping Mu
Pages: 3339-3348
Published online on: 19 February 2020

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Article

RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signaling

Sujing Zhuang, Li Li, Yuwei Zang, Guangfeng Li, Feng Wang
Pages: 3349-3355
Published online on: 03 March 2020

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Correction Open Access

[Corrigendum] Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3356-3356
Published online on: 18 February 2020

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Correction Open Access

[Corrigendum] MicroRNA‑152 suppresses cisplatin resistance in A549 cells

Wenfei Zhao, Hongyun Li, Shanshan Yang, Di Guo, Jing Chen, Shaoyi Miao, Yi Xin, Miaomiao Liang
Pages: 3357-3357
Published online on: 28 February 2020

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Correction Open Access

[Corrigendum] P130cas is required for TGF‑β1‑mediated epithelial‑mesenchymal transition in lung cancer

Bo Deng, Qun‑You Tan, Ru‑Wen Wang, Yao‑Guang Jiang, Jing‑Hai Zhou, Wei Huang
Pages: 3358-3358
Published online on: 20 February 2020

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Correction Open Access

[Corrigendum] Loss of E‑cadherin promotes prostate cancer metastasis via upregulation of metastasis‑associated gene 1 expression

Liangsheng Fan, Hongyan Wang, Xi Xia, Yumei Rao, Xiangyi Ma, Ding Ma, Peng Wu, Gang Chen
Pages: 3359-3359
Published online on: 28 February 2020

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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ARID3A knockdown facilitates ferroptosis partly through modulation of the PTEN/Akt pathway in breast cancer

Pengfei Shi, Yan Yi, Maojie Zhang, Yongjun Liu, Ming Jiang, Jiaming Zhang
Article Number: 378
Published online on: 29 June 2026

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A genome‑wide Mendelian randomization study focusing on endoplasmic reticulum stress reveals novel genetic markers for renal cell carcinoma

Bingli Gao, Zhaojun Li, Jihan Shi, Junwen Shen
Article Number: 377
Published online on: 26 June 2026

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Prognostic impact of low skeletal muscle mass in stage I‑III colon cancer: A retrospective study

Chen Mi, Feng Cui, Hanteng Yang
Article Number: 376
Published online on: 26 June 2026

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Superior cancer detection with transperineal biopsy in patients with an elevated prostate‑specific antigen level and a PI‑RADS score of 3‑4: A retrospective cohort study

Jun Zhang, Hui Zheng
Article Number: 375
Published online on: 25 June 2026

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Article

Association between fibroblast activation protein α expression and immune environment in gastric cancer

Kosuke Kubo, Yukinori Kurokawa, Takaomi Hagi, Shinnosuke Nagano, Tsuyoshi Takahashi, Takuro Saito, Kazuyoshi Yamamoto, Kota Momose, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Article Number: 374
Published online on: 25 June 2026

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Review Open Access

Clinicopathological features and therapeutic advances in primary pulmonary lymphoepithelioma‑like carcinoma (Review)

Yong Chen, Yonglin Yu, Xiaoju Chen
Article Number: 373
Published online on: 25 June 2026

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Expression of Concern Open Access

[Expression of Concern] Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process

Hongxin Ma, Lei Zhu, Jingna Ren, Benlong Rao, Maomao Sha, Yi Kuang, Weigan Shen, Zhengxin Xu
Article Number: 372
Published online on: 24 June 2026

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FBXL5 depletion as a novel strategy against osteosarcoma: Evidence for MEK/ERK inhibition and enhanced therapeutic sensitivity

Yan-Chao Ma, Wen-Ming Zhou, Yong-Qiang Shi, Yan-Bo Dong, Hai-Hong Zhang, Wei Nan
Article Number: 371
Published online on: 24 June 2026

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Special Issue

Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis

Changfeng Liu, Bing Zhang, Ye Jin, Zhi Chen, Miaomiao Wang, Zujian Wu
Article Number: 370
Published online on: 24 June 2026

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SUMOylation inhibitor TAK‑981 suppresses proliferation and induces apoptosis in SK‑UT‑1B uterine leiomyosarcoma cells

Hosouk Joung, Hyunju Liu
Article Number: 369
Published online on: 24 June 2026

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Methylation of the BMP6, BRCA1, ESR2, GSTP1 and TIMP3 genes in Mexican women with breast cancer and benign disease

Samantha Rebeca de la Torre-Guzmán, Andrea Marlene García Muro, Brenda Pelayo-Chávez, Carolina Vázquez-Gastélum, Martha Patricia Gallegos-Arreola, Ernesto Soto-Reyes, Sergio Osvaldo Meza-Chavolla, Josefina Yoaly Sánchez-López
Article Number: 368
Published online on: 24 June 2026

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Article Open Access

Identification of neoadjuvant chemoradiotherapy resistance‑associated proteins in locally advanced rectal cancer: A pilot study

Jiang-Yi He, Yan Dong, Can Chen, Fang-Hao Lu, Feng-Wei Ran, Qiong Ding, Yun Du, Tao-Rui Liu, Yu-Ying Zhang, Teng Wang, Yu-Han Chen, Xiang Zhao, Sen-Lin Xu, Jian-Jun Li
Article Number: 367
Published online on: 24 June 2026

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Overexpression of EZH2 is associated with clinicopathological parameters and poor prognosis in gliomas

Can Peng, Wei Chen, Jun Yang, Li Wang, Lixia Lu, Rong Ge
Article Number: 366
Published online on: 24 June 2026

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Correction Open Access

[Corrigendum] Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF‑1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase‑3 signaling pathway in small cell lung cancer

Wenli Jiang, Linghong Meng, Guangming Xu, Cuiting Lv, Hongliang Wang, He Tian, Ruohua Chen, Binghua Jiao, Bingui Wang, Caiguo Huang
Article Number: 365
Published online on: 22 June 2026

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A HRH1‑YAP1 feedback loop drives pancreatic cancer progression and predicts therapeutic response

Junliang Chen, Jun Wen
Article Number: 364
Published online on: 19 June 2026

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Salivary duct carcinoma with heterotopic ossification in the parotid gland: A case report

Yutaro Fukuma, Mitsuaki Ishida, Akinori Sasaki, Tsuyoshi Jinnin, Tetsuya Terada, Shin-Ichi Haginomori, Yoshinobu Hirose
Article Number: 363
Published online on: 19 June 2026

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Case Report Open Access

Pathological fracture of primary lymphoma of bone: A case report on diagnosis and novel surgical management

Duc Thanh Tran, Van Khanh Nguyen, Tran Quang Sang Nguyen, Minh Quang Dang, Van Anh Nguyen, The Hung Le, Tuyet Thanh Hai Tran, Van Cong Tran, Thi Thu Hien Tran, Trung Dung Tran
Article Number: 362
Published online on: 19 June 2026

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Review Open Access

Application and challenges of chimeric antigen receptor T cell therapy in the treatment of acute myeloid leukemia (Review)

Jingjing Zhang, Feilin Wang, Dandan Sui, Ziyi Huang, Yijian Chen
Article Number: 361
Published online on: 19 June 2026

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Article Open Access

Prognostic value of the preoperative lactate dehydrogenase‑to‑albumin ratio in patients with gastrointestinal cancer

Yean Yu, Li Yan, Kun Lv, Tianhui Huang
Article Number: 360
Published online on: 18 June 2026

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Correction Open Access

[Corrigendum] Overexpression of lncRNA AFAP1‑AS1 promotes cell proliferation and invasion in gastric cancer  

Zhouxiao Li, Zhili Ding, Dawei Rong, Weiwei Tang, Hongyong Cao
Article Number: 359
Published online on: 18 June 2026

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Case Report Open Access

Safe management of sequential chemotherapy in a hemodialysis patient with metastatic colorectal cancer: A case report

Rika Sasaki, Nobuhito Hara, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Masayuki Takeda
Article Number: 358
Published online on: 18 June 2026

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Anti‑CD20 and ‑PD‑1 antibody effects on proliferation, apoptosis and cell cycle of endometrial cancer cells

Jinqiu Su, Jiayuan Du, Yaojie Yu, Mei Feng, Qiuyue Huang, Bing Liu, He Wang
Article Number: 357
Published online on: 17 June 2026

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Article Open Access

CD47 monoclonal antibody enhances the inhibitory effect of anti‑HER2 chimeric antigen receptor macrophages on ovarian cancer

Jie Qiao, Qing Kou, Ji Qiu
Article Number: 356
Published online on: 17 June 2026

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Correction Open Access

[Corrigendum] Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population

Na-Yon Kim, Sung-Hyun Hwang, Yeseul Yang, Yongbaek Kim
Article Number: 355
Published online on: 17 June 2026

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Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Article

Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala-Dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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Article Open Access

A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Article Open Access

Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Longlong Luo, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Josephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review Open Access

Roles of V‑domain Ig suppressor of T‑cell activation‑mediated immunoregulation in tumor immune escape (Review)

Ying Chen, Shubo Wang, Ben Yang, Guohui Wang, Kunning Yang, Meihua Qu
Article Number: 324
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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September-2026 Volume 32 Issue 3

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Ferroptosis regulatory networks as therapeutic sensitizers in combination therapy for hepatocellular carcinoma (Review)

Mengxiao Zhu, Xiaoxiong Hu
Article Number: 416
Published online on: 17 July 2026

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Article Open Access

 Establishment of extrahepatic bile duct cancer organoids using suspension culture and their application in clinical drug screening

Wei Huang, Yuanhui Su, Cheng Yu, Yanlong Zhang, Hao Xu, Wence Zhou
Article Number: 415
Published online on: 17 July 2026

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Review Open Access

Systems biology of Wnt signaling in glioma chemotherapy resistance: Integrating multi‑omics mechanisms and emerging therapeutic vulnerabilities (Review)

Qianru Zeng, Zhuojun Chen, Rendong Zhang, Hongchao Pan
Article Number: 414
Published online on: 17 July 2026

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Article Open Access

A three‑gene signature correlated with MAPK/ERK activation characterizes acquired resistance to EGFR‑tyrosine kinase inhibitors in non‑small cell lung cancer

Changtai Qin, Wei Zhang, Dongfang Tang, Yuxi Yang, Binghui Liang, Zhiming Hu, Yuxiao Zhang, Tingjie Ye, Wei Xu
Article Number: 413
Published online on: 17 July 2026

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Review Open Access

Role of PCSK9 in hallmarks of cancer: From mechanisms to interventions (Review)

Lijuan Tang, Shu Yao, Yongheng Zhu, Zongsheng He, Bruno Ramos‑Molina, Yuanchun Xu
Article Number: 412
Published online on: 15 July 2026

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Article Open Access

PRR11 expression in early ER+/HER2‑low breast cancer: Association with estrogen receptor positivity and exploratory analysis of prognostic significance

Alper Turkel, Mutlu Dogan, Sultan Cigdem Irkkan, Haktan Bagis Erdem, Nazan Bozdogan, Taha Bahsi
Article Number: 411
Published online on: 15 July 2026

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Expression of Concern Open Access

[Expression of Concern] Elevated microRNA‑125b levels predict a worse prognosis in HER2‑positive breast cancer patients  

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou
Article Number: 410
Published online on: 15 July 2026

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Article Open Access

Association between the presence of EGFR or ALK mutations and the location of primary non‑small cell lung cancer, as well as metabolic activity observed on 18F‑FDG PET/CT scans

Inci Uslu Biner, Tuba Inal Cengiz, Ulku Yilmaz, Nalan Akyurek, Suna Kavurgaci, Pinar Akin Kabalak, Derya Kizilgoz, Ezgi Gurel Akan
Article Number: 409
Published online on: 14 July 2026

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Review Open Access

Advances in Helicobacter pylori-mediated oncogenic signaling pathways in gastric cancer: From pathological evolution to clinical application prospects (Review)

Tingting Ding, Wenjun Hu, Xiaogai Qi, Yakun Zhang, Hui Wang
Article Number: 408
Published online on: 14 July 2026

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Article

Clinical and biological significance of TROY (TNFRSF19) splice variants in colorectal cancer

Mitsuaki Nishioka, Yuki Kunimune, Yutaka Suehiro, Masaki Kodama, Akiyo Ishiguro, Tatsuya Takagi, Jun Nishikawa, Hidenori Takahashi, Hiroto Matsui, Shinobu Tomochika, Koichi Hamabe, Shinichi Hashimoto, Hiroaki Nagano, Taro Takami, Takahiro Yamasaki
Article Number: 407
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Sirtuin 7 promotes glioma proliferation and invasion through activation of the ERK/STAT3 signaling pathway

Pengfei Mu, Kun Liu, Qingyuan Lin, Wensheng Yang, Dan Liu, Zhen Lin, Wei Shao, Tianhai Ji
Article Number: 406
Published online on: 13 July 2026

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Article

Molecular signatures of triple‑negative breast cancer cells acquiring palbociclib resistance via continuous exposure

Daichi Enomoto, Yumika Iwasa, Natsuho Irie, Haruki Ohata, Yuki Uemichi, Miyuki Mabuchi, Tadashi Shimizu, Kohji Takara
Article Number: 405
Published online on: 10 July 2026

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Review Open Access

Gastrointestinal conventional carcinoma with neuroendocrine differentiation: From pathological phenomenon to clinical importance (Review)

Chenyang Zhou, Shizheng Tong, Danfeng Zhou, Yixin Pan, Jingjing Xu, Sunbin Ling, Wei Wu, Tingting Feng
Article Number: 404
Published online on: 09 July 2026

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Review Open Access

Cell‑cycle reactivation and hepatocyte identity loss in hepatocellular carcinoma: Transcriptomic hallmarks and validation strategies (Review)

Jichen Hou, Bing Zhu, Lu Liang
Article Number: 403
Published online on: 09 July 2026

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Case Report Open Access

Primary thymic papillary adenocarcinoma with a rare CD5/CD117‑negative and PAX8/WT1‑positive immunophenotype: A case report

Dequan Zhu, Chuanzhen Wan, Jialong Guo, Tao Zeng, Wei Wang
Article Number: 402
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Fatty acids inhibit anticancer effects of 5‑fluorouracil in mouse cancer cell lines

Eriko Tanabe, Misaho Kitayoshi, Kiyomu Fujii, Hitoshi Ohmori, Yi Luo, Yui Kadochi, Shiori Mori, Rina Fujiwara, Yukiko Nishiguchi, Takamitsu Sasaki, Hiroki Kuniyasu
Article Number: 401
Published online on: 09 July 2026

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Article Open Access

A nomogram prediction model for brain metastases in patients with lung adenocarcinoma 

Hao Liu, Lan Wang, Xiaolei Zhuo, Yucheng Hu, Ziming Li, Huishan Deng, Mingshu Mo
Article Number: 400
Published online on: 08 July 2026

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Article Open Access

Survival benefits of non‑surgical triple therapy in hepatocellular carcinoma with inferior vena cava/right atrial tumor thrombus: A retrospective analysis from a multidisciplinary team

Peng Tang, Jin Li, Jiayu Duan, Xin Wang, Jin Zhou, Yu Yang, Yong Zeng
Article Number: 399
Published online on: 08 July 2026

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Article Open Access

A bioinformatics analysis of KIF transcriptomic subtyping reveals prognostic heterogeneity and differential therapeutic responses in cervical cancer

Xinyi Zhao, Jie Wu, Lan Li, Haohan Zhang, Jing Li, Hao Zhong, Yuchao Dan, Qibin Song, Hongbin Chen, Bin Xu
Article Number: 398
Published online on: 08 July 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA OIP5‑AS1 promotes the progression of esophageal cancer by regulating miR‑30a/VOPP1 expression

Jiajun Xu, Zhixi Chen, Zheng Fang, Shixiong Chen, Ying Guo, Xianfeng Liu, Kai Chen, Shengjia Chen
Article Number: 397
Published online on: 08 July 2026

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Article Open Access

FUBP3 regulates expression and alternative splicing of genes associated with cell proliferation and apoptosis in cancer cells

Lingyu Kong, Chaoxu Fu, Xuesong Li, Mingxin Chen, Xinqi Liu, Min Zhou, Tongshu Wang, Hongxin Piao
Article Number: 396
Published online on: 07 July 2026

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Article

Pan‑immune‑inflammation value as a prognostic and predictive biomarker in metastatic non‑small cell lung cancer treated with nivolumab: A real‑world study

Nedim Turan, Hacer Sahika Yildiz, Sedat Yildirim, Ezgi Turkoglu, Ugur Ozkerim, Sila Oksuz, Neslihan Buyukmurat, Hamit Bal, Heves Surmeli, Hatice Odabas
Article Number: 395
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] miR‑5590‑3p inhibits the proliferation and metastasis of renal cancer cells by targeting ROCK2 to inhibit proliferation, migration and invasion

Queling Liu, Anyi Zhu, Weiyin Gao, Fu Gui, Yan Zou, Xiaocheng Zhou, Zhengdong Hong
Article Number: 394
Published online on: 06 July 2026

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Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

Jinfen Yao, Jie Chen
Article Number: 393
Published online on: 03 July 2026

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Review Open Access

Regulatory roles of N6‑methyladenosine methylation factors in melanoma invasion and metastasis (Review)

Zhijie Xu, Wanqun Yu, Jie Liu, Xiyue Chang, Shiraz Manji Laeeqa, Zerong Xu, Qi Yang, Wanan Xiao
Article Number: 392
Published online on: 03 July 2026

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Review

Microbiota in pancreatic cancer: Roles in tumor initiation and progression (Review)

Yanjun Lou, Yiqun Fan
Article Number: 391
Published online on: 03 July 2026

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Review Open Access

Role of long non‑coding RNA HCG11 in human cancers: From molecular mechanisms to clinical applications (Review)

Qiong-Feng Tan, Bo Chen, Hai-Feng Hu, Huang Liu, Wen Huang, Wei Mu
Article Number: 390
Published online on: 03 July 2026

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Expression of Concern Open Access

[Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma

Yumiko Kondo, Kanya Honoki, Shingo Kishi, Shiori Mori, Rina Fujiwara‑Tani, Shinji Tsukamoto, Hiromasa Fujii, Hiroki Kuniyasu, Yasuhito Tanaka
Article Number: 389
Published online on: 03 July 2026

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Review Open Access

Emerging roles of O‑GlcNAcylation in tumorigenesis, immunosuppression and drug resistance (Review)

Yuntong Liu, Yumo Han, Shumei Ding, Han Deng, Shiyue Li, Yingyu Zhang, Haimeng Yin, Bo You
Article Number: 388
Published online on: 02 July 2026

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Article Open Access

Efficacy and safety of immune checkpoint inhibitors combined with anti‑angiogenic agents for advanced cervical cancer: A systematic review and meta‑analysis

Hengchang Chen, Xue Yang, Yulu Qin, Wentong Xu, Mingzhu Jiao, Xinyu Lu, Yaxu Su, Fengjuan Zhou, Yong Xin
Article Number: 387
Published online on: 02 July 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

Dong Wang, Xiaohou Wu
Article Number: 386
Published online on: 02 July 2026

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Article Open Access

Lymphocyte‑to‑C‑reactive protein ratio as a clinically feasible nutrition‑inflammation marker for predicting outcomes in patients with gastric cancer

Kai Liu, Lai Chang
Article Number: 385
Published online on: 02 July 2026

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Article Open Access

Identification and validation of aging‑related genes in patients with multiple myeloma

Huajing Liu, Senhua Song, Yingtao Wu, Yu Wang, Yueping Liu, Ying Liu
Article Number: 384
Published online on: 02 July 2026

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Retraction Open Access

[Retracted] miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang
Article Number: 383
Published online on: 01 July 2026

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Article Open Access

Air pollution and hepatocellular carcinoma: Integrated network toxicology, machine learning, molecular docking and multiomics analysis

Xiaorong Wang, Huihao Qin, Jing Jing, Yun Liu, Lei Guo, Hongquan Liu, Wei Zhang
Article Number: 382
Published online on: 30 June 2026

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Case Report Open Access

Cervical metastasis in breast cancer: A case report

Xinru Liu, Ke Sun, Hongming Zhu, Tonghua Du, Liyang Sheng, Bin Liu
Article Number: 381
Published online on: 30 June 2026

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Review Open Access

New and emerging strategies for targeting cancers: Challenges and opportunities (Review)

Sreenivasa R. Chinni, Arun K. Rishi, Kaladhar B. Reddy
Article Number: 380
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Article Number: 379
Published online on: 29 June 2026

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