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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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October-2020 Volume 22 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Differential roles of Scavenger receptor class B type I: A protective molecule and a facilitator of atherosclerosis (Review)

Baitao Ma, Jing Jia, Xuebin Wang, Rui Zhang, Shuai Niu, Leng Ni, Xiao Di, Changwei Liu
Pages: 2599-2604
Published online on: 28 July 2020

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Article Open Access

Upregulated lncRNA Pvt1 may be important for cardiac remodeling at the infarct border zone

Baihui Liu, Yuanjuan Cheng, Jiakun Tian, Li Zhang, Xiaoqian Cui
Pages: 2605-2616
Published online on: 28 July 2020

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Article Open Access

Moderate hypothermia induces protection against hypoxia/reoxygenation injury by enhancing SUMOylation in cardiomyocytes

Jinsheng Chen, Xiyun Bian, Yanxia Li, Xiaolin Xiao, Yanying Yin, Xinping Du, Cuancuan Wang, Lili Li, Yaowu Bai, Xiaozhi Liu
Pages: 2617-2626
Published online on: 28 July 2020

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Article Open Access

De novo transcriptome analysis and gene expression profiling of fish scales isolated from Carassius auratus during space flight: Impact of melatonin on gene expression in response to space radiation

Yukihiro Furusawa, Tatsuki Yamamoto, Atsuhiko Hattori, Nobuo Suzuki, Jun Hirayama, Toshio Sekiguchi, Yoshiaki Tabuchi
Pages: 2627-2636
Published online on: 28 July 2020

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Article Open Access

TIMP3/TGF‑β1 axis regulates mechanical loading‑induced chondrocyte degeneration and angiogenesis

De‑Lai Zhao, Hong‑Tao Li, Shao‑Hui Liu
Pages: 2637-2644
Published online on: 29 July 2020

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Article Open Access

miR‑204‑5p promotes apoptosis and inhibits migration of gastric cancer cells by targeting HER‑2

Shu Yang, Binni Chen, Baogen Zhang, Caiping Li, Yuena Qiu, Hanhui Yang, Zhongxin Huang
Pages: 2645-2654
Published online on: 28 July 2020

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Article Open Access

Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF‑1α and apoptosis

Wangnan Sun, Aiqun Li, Zhiqiang Wang, Xuhong Sun, Menghua Dong, Fu Qi, Lin Wang, Yueheng Zhang, Pengchao Du
Pages: 2655-2664
Published online on: 28 July 2020

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Article Open Access

Impaired lipophagy in endothelial cells with prolonged exposure to oxidized low‑density lipoprotein

Cai‑Ping Zhang, Xin‑Xin Ding, Tian Tian, Bo‑Jie Li, Chu‑Yao Wang, Su‑Su Jiang, Jin‑Qi Shao, Yu‑Lin Yuan, Ying Tian, Min Zhang, Shi‑Yin Long
Pages: 2665-2672
Published online on: 16 July 2020

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Article Open Access

High lymphocyte‑to‑monocyte ratio is associated with low α‑fetoprotein expression in patients with hepatitis B virus‑associated hepatocellular carcinoma

Haixia Wang, Yu Xiang, Xinyu Li, Shuang Liu, Linxiu Liu
Pages: 2673-2684
Published online on: 29 July 2020

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Article Open Access

Long non‑coding RNA SNHG16 inhibits the oxygen‑glucose deprivation and reoxygenation‑induced apoptosis in human brain microvascular endothelial cells by regulating miR‑15a‑5p/bcl‑2

Hongwei Teng, Ming Li, Lei Qian, Hua Yang, Mingzhi Pang
Pages: 2685-2694
Published online on: 29 July 2020

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Article Open Access

Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis

Xing Wu, Shiyu Pan, Weiwei Luo, Zhaohua Shen, Xiangrui Meng, Mengwei Xiao, Bei Tan, Kai Nie, Ting Tong, Xiaoyan Wang
Pages: 2695-2704
Published online on: 23 July 2020

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Article Open Access

Plasma levels of methylated septin 9 are capable of detecting hepatocellular carcinoma and hepatic cirrhosis

Na He, Gong Feng, Chunyan Zhang, Fangxiong Wu, Ting Zhang, Yongqin Yang
Pages: 2705-2714
Published online on: 23 July 2020

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Article Open Access

Evaluation of the effects of IL‑22 on the proliferation and differentiation of keratinocytes in vitro

Le Zhuang, Weiyuan Ma, Jianjun Yan, Hua Zhong
Pages: 2715-2722
Published online on: 20 July 2020

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Article Open Access

MicroRNA‑15b‑5p exerts its tumor repressive role via targeting GDI2: A novel insight into the pathogenesis of thyroid carcinoma

Jidong Zou, Jiantong Qian, Haiyan Fu, Fawen Yin, Wanjun Zhao, Liang Xu
Pages: 2723-2732
Published online on: 15 July 2020

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Article Open Access

Phosphorylation of STAT3 and ERBB2 mediates hypoxia‑induced VEGF release in ARPE‑19 cells

Soohyun Hwang, Hyemin Seong, Jinhyun Ryu, Joo Yeon Jeong, Tae Seen Kang, Ki Yup Nam, Seong Wook Seo, Seong Jae Kim, Sang Soo Kang, Yong Seop Han
Pages: 2733-2740
Published online on: 16 July 2020

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Article Open Access

Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway

Mingyang Yu, Yunguang Wang, Yao Zhang, Daping Cui, Guishan Gu, Dewei Zhao
Pages: 2741-2752
Published online on: 16 July 2020

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Article Open Access

Preconditioning mesenchymal stromal cells with flagellin enhances the anti‑inflammatory ability of their secretome against lipopolysaccharide‑induced acute lung injury

Rui Li, Yu Li, Xiaoyan Dong
Pages: 2753-2766
Published online on: 28 July 2020

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Article Open Access

Role of the HIF‑1α/SDF‑1/CXCR4 signaling axis in accelerated fracture healing after craniocerebral injury

Yonghua Xue, Zhikun Li, Yi Wang, Xiaodong Zhu, Ruixi Hu, Wei Xu
Pages: 2767-2774
Published online on: 28 July 2020

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Article Open Access

Effect of ultra‑wide‑band electromagnetic pulses on blood‑brain barrier permeability in rats

Peng Gao, Qin Chen, Junfeng Hu, Yanyun Lin, Jiajin Lin, Qiyan Guo, Hao Yue, Yan Zhou, Lihua Zeng, Jing Li, Guirong Ding, Guozhen Guo
Pages: 2775-2782
Published online on: 28 July 2020

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Article Open Access

Protective effect of dimethyl fumarate on oxidative damage and signaling in cardiomyocytes

Yuanyuan Kuang, Yinzhuang Zhang, Zhen Xiao, Lijun Xu, Ping Wang, Qilin Ma
Pages: 2783-2790
Published online on: 15 July 2020

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Article Open Access

CD9 knockdown suppresses cell proliferation, adhesion, migration and invasion, while promoting apoptosis and the efficacy of chemotherapeutic drugs and imatinib in Ph+ ALL SUP‑B15 cells

Chongyun Xing, Wanling Xu, Yifen Shi, Bin Zhou, Dijiong Wu, Bin Liang, Yuhong Zhou, Shenmeng Gao, Jianhua Feng
Pages: 2791-2800
Published online on: 20 July 2020

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Article Open Access

Grooved hydroxyapatite scaffold modulates mitochondria homeostasis and thus promotes osteogenesis in bone mesenchymal stromal cells Retraction in /10.3892/mmr.2025.13519

Chenglong Li, Lu Yang, Xiaohua Ren, Mu Lin, Daonan Shen, You Li, Xiangyu Zhang, Chunhui Liu, Yandong Mu
Pages: 2801-2809
Published online on: 23 July 2020

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Article Open Access

Downregulated miR‑130a enhances the sensitivity of acute myeloid leukemia cells to Adriamycin

Huimin Liu, Min Liu, Jiangzhao Zhang, Yan Liang
Pages: 2810-2816
Published online on: 28 July 2020

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Article Open Access

MicroRNA‑92a promotes non‑small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7

Da Ni, Jiping Teng, Youshuang Cheng, Zhijun Zhu, Bufeng Zhuang, Zhiyin Yang
Pages: 2817-2825
Published online on: 28 July 2020

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Article Open Access

Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC‑27

Yingwei Sun, Rongrong Deng, Cuiwei Zhang
Pages: 2826-2832
Published online on: 28 July 2020

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Article Open Access

Baicalin alleviates collagen‑induced arthritis and suppresses TLR2/MYD88/NF‑κB p65 signaling in rats and HFLS‑RAs

Lin Bai, Ya Bai, Yuxin Yang, Wei Zhang, Ling Huang, Rui Ma, Li Wang, Haizheng Duan, Qiaofeng Wan
Pages: 2833-2841
Published online on: 28 July 2020

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Article Open Access

Long non‑coding RNA SNHG12 regulates cell proliferation, invasion and migration in endometrial cancer by targeting miR‑4429

Pengyu Cai, Mingxiu Wu, Bin Zhang, Shuyi Wu, Haiyun Wei, Li Wei
Pages: 2842-2850
Published online on: 28 July 2020

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Article Open Access

Single immunoglobulin and Toll‑interleukin‑1 receptor domain containing molecule protects against severe acute pancreatitis in vitro by negatively regulating the Toll‑like receptor‑4 signaling pathway: A clinical and experimental study

Rulin Zhao, Conghua Song, Li Liu, Qiong Liu, Nanjin Zhou, Xiaojiang Zhou, Yong Xie
Pages: 2851-2859
Published online on: 28 July 2020

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Article Open Access

Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats

Boyan Liu, Junli Xue, Mengyu Zhang, Mingyue Wang, Tingting Ma, Min Zhao, Qianqian Gu, Shucun Qin
Pages: 2860-2868
Published online on: 28 July 2020

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Article Open Access

lncRNA HEIH, an indicator of high malignancy and poor prognosis, functions as an oncogene in breast cancer

Cheng Chen, Cheng Gu, Qian Ren, Fanghui Ding, Qing Pan, Yicong Niu, Dachang Ma, Li Wu
Pages: 2869-2877
Published online on: 23 July 2020

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Article Open Access

Solanum nigrum Linne improves DNCB‑induced atopic dermatitis‑like skin disease in BALB/c mice

Sooyeon Hong, Bina Lee, Jae‑Hyun Kim, Eun‑Young Kim, Minsun Kim, Boguen Kwon, Hye‑Rin Cho, Youngjoo Sohn, Hyuk‑Sang Jung
Pages: 2878-2886
Published online on: 28 July 2020

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Article Open Access

Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis Retraction in /10.3892/mmr.2025.13538

Xu Chen, Jun Yin, Yuyin Xu, Zhi Qiu, Jing Liu, Xiaolan Chen
Pages: 2887-2895
Published online on: 23 July 2020

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Article Open Access

Propofol protects against oxygen/glucose deprivation‑induced cell injury via gap junction inhibition in astrocytes

Yanting Fan, Siyu Zhu, Jing Wang, Yuping Zhao, Xudong Wang
Pages: 2896-2904
Published online on: 28 July 2020

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Article Open Access

Downregulating CREBBP inhibits proliferation and cell cycle progression and induces daunorubicin resistance in leukemia cells

Chao Gao, Shu‑Guang Liu, Wen‑Ting Lu, Zhi‑Xia Yue, Xiao‑Xi Zhao, Tian‑Yu Xing, Zhen‑Ping Chen, Hu‑Yong Zheng, Zhi‑Gang Li
Pages: 2905-2915
Published online on: 17 July 2020

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Article Open Access

NCAPH is negatively associated with Mcl‑1 in non‑small cell lung cancer

Qiuxia Xiong, Songqing Fan, Lincan Duan, Baiyang Liu, Xiulin Jiang, Xiaobo Chen, Chunyan Xiong, Qingyuan Tao, Juan Wang, Hui Zhang, Chuanjiang Chen, Yong Duan
Pages: 2916-2924
Published online on: 28 July 2020

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Article Open Access

A clinical and multi‑omics study of Van der Woude syndrome in three generations of a Chinese family

Kai Yang, Xing‑Yue Dong, Jue Wu, Jian‑Jiang Zhu, Ya Tan, You‑Sheng Yan, Li Lin, Dong‑Liang Zhang
Pages: 2925-2931
Published online on: 28 July 2020

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Article Open Access

Role of exercise and rapamycin on the expression of energy metabolism genes in liver tissues of rats fed a high‑fat diet

Genghong Tu, Chunyan Dai, Haofei Qu, Yunzhen Wang, Bagen Liao
Pages: 2932-2940
Published online on: 28 July 2020

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Article Open Access

EphA2‑enriched exosomes promote cell migration and are a potential diagnostic serum marker in pancreatic cancer

Qian Wei, Lijuan Wei, Jingya Zhang, Ze Li, Honglei Feng, Li Ren
Pages: 2941-2947
Published online on: 28 July 2020

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Article Open Access

Novel oral plasminogen activator inhibitor‑1 inhibitor TM5275 attenuates hepatic fibrosis under metabolic syndrome via suppression of activated hepatic stellate cells in rats

Ryuichi Noguchi, Kosuke Kaji, Tadashi Namisaki, Kei Moriya, Hideto Kawaratani, Mitsuteru Kitade, Hiroaki Takaya, Yosuke Aihara, Akitoshi Douhara, Kiyoshi Asada, Norihisa Nishimura, Toshio Miyata, Hitoshi Yoshiji
Pages: 2948-2956
Published online on: 28 July 2020

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Article Open Access

Mannose shows antitumour properties against lung cancer via inhibiting proliferation, promoting cisplatin‑mediated apoptosis and reducing metastasis

Youyu Wang, Shenglong Xie, Bin He
Pages: 2957-2965
Published online on: 23 July 2020

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Article

Downregulated Mucin 1 alleviates paclitaxel resistance in non‑small cell lung cancer cells

Hongyu Xu, Hui Gao, Hua Li, Dong Li, Weiwei Yuan, Ling Zhang, Peng Cheng, Xiaomei Su, Zhihui Li, Guangjie Wang, Tao Zhang
Pages: 2966-2972
Published online on: 20 July 2020

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Article

Different MAPK signal transduction pathways play different roles in the impairment of glucose‑stimulated insulin secretion in response to IL‑1β

Yang Ou, Zhongxiong Zheng, Ben Niu, Jian Su, Heng Su
Pages: 2973-2980
Published online on: 28 July 2020

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Article

Knockdown of Ror2 suppresses TNF‑α‑induced inflammation and apoptosis in vascular endothelial cells

Xiaohu Yang, Suming Zhao, Hongxin Yuan, Rongfeng Shi, Weiwei Gu, Zhuxin Gu, Xiaohua Lu , Hui Zhao
Pages: 2981-2989
Published online on: 28 July 2020

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Article

MicroRNA‑130a‑3p promotes the proliferation and inhibits the apoptosis of cervical cancer cells via negative regulation of RUNX3

Meng Wang, Xiaoxia Wang, Wenfeng Liu
Pages: 2990-3000
Published online on: 28 July 2020

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Article

Decrease in matrix metalloproteinase‑3 activity in systemic sclerosis fibroblasts causes α2‑antiplasmin and extracellular matrix deposition, and contributes to fibrosis development

Hirofumi Niwa, Yosuke Kanno, En Shu, Mariko Seishima
Pages: 3001-3007
Published online on: 28 July 2020

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Article

Angiotensin‑converting enzyme‑2 improves diabetic nephropathy by targeting Smad7 for ubiquitin degradation

Ziye Chen, Xinpan Chen, Yu Bai, Zongli Diao, Wenhu Liu
Pages: 3008-3016
Published online on: 28 July 2020

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Article

Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis

Yan Zhao, Jianghui Liu, Liang Liu
Pages: 3017-3022
Published online on: 15 July 2020

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Comment Open Access

[Comment] The COVID‑19 pandemic as a scientific and social challenge in the 21st century

Vassilios Zoumpourlis, Maria Goulielmaki, Emmanouil  Rizos, Stella Baliou, Demetrios A. Spandidos
Pages: 3035-3048
Published online on: 30 July 2020

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Review Open Access

GAS5‑mediated regulation of cell signaling (Review)

Yang Zhou, Binghai Chen
Pages: 3049-3056
Published online on: 19 August 2020

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Article Open Access

Emerging role of circular RNA in intervertebral disc degeneration: Knowns and unknowns (Review)

Yongjin Li, Suzhe Zhou, Peng Peng, Xuke Wang, Lilong Du, Zhenxin Huo, Baoshan Xu
Pages: 3057-3065
Published online on: 19 August 2020

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Article Open Access

Efficient proliferation and mitosis of glioblastoma cells infected with human cytomegalovirus is mediated by RhoA GTPase

Ahmed A. Al‑Qahtani, Saud Alarifi, Saad Alkahtani, Christos Stournaras, George Sourvinos
Pages: 3066-3072
Published online on: 19 August 2020

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Article Open Access

Fluoxetine regulates glucose and lipid metabolism via the PI3K‑AKT signaling pathway in diabetic rats

Hailong Yang, Qiuyun Cao, Xiaolu Xiong, Peng Zhao, Diwen Shen, Yuzhe Zhang, Ning Zhang
Pages: 3073-3080
Published online on: 04 August 2020

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Article Open Access

Competing endogenous RNA network analysis for screening inflammation‑related long non‑coding RNAs for acute ischemic stroke

Li Zhang, Baihui Liu, Jinhua Han, Tingting Wang, Lin Han
Pages: 3081-3094
Published online on: 04 August 2020

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Article Open Access

Downregulation of lncRNA H19 alleviates atherosclerosis through inducing the apoptosis of vascular smooth muscle cells

Hui Sun, Qianqian Jiang, Li Sheng, Kai Cui
Pages: 3095-3102
Published online on: 31 July 2020

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Article Open Access

NDRG2 attenuates ischemia-induced astrocyte necroptosis via the repression of RIPK1

Jie Zhu, Li-Kun Yang, Qiu-Hong Wang, Wei Lin, Yi Feng, Ye-Ping Xu, Wei-Liang Chen, Kun Xiong, Yu-Hai Wang
Pages: 3103-3110
Published online on: 07 August 2020

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Article Open Access

IFN‑γ induces apoptosis in human melanocytes by activating the JAK1/STAT1 signaling pathway

Qianya Su, Fei Wang, Zhengbang Dong, Mei Chen, Rong Cao
Pages: 3111-3116
Published online on: 03 August 2020

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Article Open Access

Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice

Yuanping Shi, Hongyao Liu, Hong Liu, Yang Yu, Jun Zhang, Yanfei Li, Guanghua Luo, Xiaoying Zhang, Ning Xu
Pages: 3117-3126
Published online on: 11 August 2020

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Article Open Access

Inhibition of HtrA2 alleviates inflammatory response and cell apoptosis in lipopolysaccharide‑induced acute pneumonia in rats

Xin Wang
Pages: 3127-3134
Published online on: 04 August 2020

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Article Open Access

Density of Musashi‑1‑positive stem cells in the stomach of patients with irritable bowel syndrome

Magdy El‑Salhy, Trygve Hausken, Jan Gunnar Hatlebakk
Pages: 3135-3140
Published online on: 04 August 2020

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Article Open Access

TNF‑α regulates the osteogenic differentiation of bone morphogenetic factor 9 adenovirus‑transduced rat follicle stem cells via Wnt signaling

Xinyue Li, Ge Ren, Changjun Cai, Xia Yang, Li Nie, Xueqin Jing, Conghua Li
Pages: 3141-3150
Published online on: 19 August 2020

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Icariside II ameliorates myocardial ischemia and reperfusion injury by attenuating inflammation and apoptosis through the regulation of the PI3K/AKT signaling pathway

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Identification of pivotal genes and pathways in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis through integrated bioinformatic analysis

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Panax notoginseng Saponins protect auditory cells against cisplatin‑induced ototoxicity by inducing the AKT/Nrf2 signaling‑mediated redox pathway

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Expression of TNF‑α and IL‑β can be suppressed via the PPAR‑γ/mTOR signaling pathway in BV‑2 microglia: A potential anti‑inflammation mechanism

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TRPM2 expression levels are associated with histological grading in patients with tongue squamous cell carcinoma

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Published online on: 05 August 2020

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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Yan Shi, Shu-Ai Hou
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
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Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Article Number: 25
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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
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Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

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Published online on: 31 October 2025

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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
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Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
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Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
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Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

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Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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