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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2019 Volume 17 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

SUN2: A potential therapeutic target in cancer (Review)

Xin Chen, Yu Chen, Hui‑Min Huang, Hai‑Di Li, Fang‑Tian Bu, Xue‑Yin Pan, Yang Yang, Wan‑Xia Li, Xiao‑Feng Li, Cheng Huang, Xiao‑Ming Meng, Jun Li
Pages: 1401-1408
Published online on: 27 November 2018

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Review Open Access

Circulating tumor DNA detection: A potential tool for colorectal cancer management (Review)

Huizi Li, Changwen Jing, Jianzhong Wu, Jie Ni, Huanhuan Sha, Xiaoyue Xu, Yuanyuan Du, Rui Lou, Shuchen Dong, Jifeng Feng
Pages: 1409-1416
Published online on: 05 December 2018

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Review Open Access

The prognostic value of S100A10 expression in cancer (Review)

Normastuti Adhini Tantyo, Azrina Saraswati Karyadi, Siti Zulimas Rasman, Marvelmario Reginald Gabriel Salim, Astrella Devina, Anton Sumarpo
Pages: 1417-1424
Published online on: 23 November 2018

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Article Open Access

Tumor immunohistochemistry and preoperative magnetic resonance imaging features predict local recurrence of giant cell tumor of bone following intralesional curettage

Yifeng He, Yu Zhou, Ji Zhang, Fei Yuan, Jun Wang, Lianjun Du, Qi Zhou, Jing Liang, Xiaoyi Ding
Pages: 1425-1434
Published online on: 30 November 2018

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Article Open Access

Prognostic significance of the combination of preoperative fibrinogen and the neutrophil‑lymphocyte ratio in patients with non‑small cell lung cancer following surgical resection

Hua‑Gang Liang, Kun Gao, Rui Jia, Jian Li, Chao Wang
Pages: 1435-1444
Published online on: 26 November 2018

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Article Open Access

Sirtuin 7 promotes glioma proliferation and invasion through activation of the ERK/STAT3 signaling pathway

Pengfei Mu, Kun Liu, Qingyuan Lin, Wensheng Yang, Dan Liu, Zhen Lin, Wei Shao, Tianhai Ji
Pages: 1445-1452
Published online on: 06 December 2018

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Article Open Access

miR‑200b and miR‑200c co‑contribute to the cisplatin sensitivity of ovarian cancer cells by targeting DNA methyltransferases Retraction in /10.3892/ol.2025.14951

Jue Liu, Xiaobo Zhang, Yuliang Huang, Qunfeng Zhang, Jianbin Zhou, Xiaodi Zhang, Xiaoxu Wang
Pages: 1453-1460
Published online on: 22 November 2018

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Article Open Access

The effects of Tim‑3 activation on T‑cells in gastric cancer progression

Jiangtao Yu, Huanhu Zhang, Shengbo Sun, Shaowei Sun, Leping Li
Pages: 1461-1466
Published online on: 21 November 2018

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Article Open Access

Radium‑223 in patients with metastatic castration‑resistant prostate cancer: Efficacy and safety in clinical practice

Arsela Prelaj, Sara Elena Rebuzzi, Federica Buzzacchino, Chiara Pozzi, Carla Ferrara, Viviana Frantellizzi, Giulia Anna Follacchio, Liana Civitelli, Giuseppe De Vincentis, Silverio Tomao, Vincenzo Bianco
Pages: 1467-1476
Published online on: 30 November 2018

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Article Open Access

Orbital precursor B‑lymphoblastic lymphoma involving the extraocular muscles in a 56‑year‑old male and a review of the literature

Rasmus Ejstrup, Lauge Hjorth Mikkelsen, Mette Klarskov Andersen, Erik Clasen‑Linde, Lise Mette Rahbek Gjerdrum, Setareh Safavi, Steffen Heegaard
Pages: 1477-1482
Published online on: 19 November 2018

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Article Open Access

Diagnosis of mesothelioma with deep learning

Xue Hu, Zebo Yu
Pages: 1483-1490
Published online on: 26 November 2018

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Article Open Access

Overexpression of grainyhead‑like transcription factor 2 is associated with poor prognosis in human pancreatic carcinoma

Gang Wang, Jingen Pan, Lu Zhang, Cheng Wang
Pages: 1491-1496
Published online on: 21 November 2018

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Article

Serum chromogranin A for the diagnosis of gastroenteropancreatic neuroendocrine neoplasms and its association with tumour expression

Chuan Zhang, Yue Huang, Jiang Long, Xiaochen Yao, Jun Wang, Shimin Zang, Wei Qu, Feng Wang
Pages: 1497-1504
Published online on: 05 December 2018

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Article Open Access

Use of clinical nomograms for predicting survival outcomes in young women with breast cancer

Hui Lin, Fan Zhang, Luanhong Wang, De Zeng
Pages: 1505-1516
Published online on: 28 November 2018

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Article Open Access

Effects and possible mechanism of a picosecond pulsed electric field on angiogenesis in cervical cancer in vitro

Limei Wu, Yutong Wu, Zhengai Xiong, Chenguo Yao, Manman Zeng, Ruizhe Zhang, Yuanyuan Hua
Pages: 1517-1522
Published online on: 30 November 2018

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Article Open Access

Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma

Dan‑Dan Zhao, Jun Yuan, Qi Cheng, Ya‑Ling Qi, Ke Lu, Shan‑Shan Lai, Qian Sun, Yue Zhao, Lei Fang, Mei‑Ling Jin, De‑Cai Yu, Yu‑Dong Qiu, Chao‑Jun Li, Jun Chen, Bin Xue
Pages: 1523-1530
Published online on: 07 December 2018

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Article Open Access

Effect of NOS1 regulating ABCG2 expression on proliferation and apoptosis of cervical cancer cells

Mingde Ding, Hui Zhang, Lei Liu, Ruilan Liang
Pages: 1531-1536
Published online on: 30 November 2018

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Article Open Access

Analysis of PKC‑ζ protein levels in normal and malignant breast tissue subtypes

Tracess Smalley, S. M. Anisul Islam, Christopher Apostolatos, André Apostolatos, Mildred Acevedo‑Duncan
Pages: 1537-1546
Published online on: 04 December 2018

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Article Open Access

Therapeutic effect and adverse reaction of sorafenib in the treatment of advanced renal cancer

Juhui Qiu, Dongjian Liu, Zaichun Yan, Wei Jiang, Qinglei Zhang, Ning Li, Wentao Deng, Kejia Ding
Pages: 1547-1550
Published online on: 28 November 2018

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Article Open Access

Higher nuclear EGFR expression is a better predictor of survival in rectal cancer patients following neoadjuvant chemoradiotherapy than cytoplasmic EGFR expression

Ching‑Chieh Yang, Li‑Ching Lin, Yu‑Wei Lin, Yu‑Feng Tian, Chen‑Yi Lin, Ming‑Jen Sheu, Chien‑Feng Li, Ming‑Hong Tai
Pages: 1551-1558
Published online on: 26 November 2018

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Article Open Access

Expression of p53 in ground‑glass nodule of lung cancer and non‑lung cancer patients

Zhihua Teng, Wen Chen, Dongyong Yang, Zhenghua Zhang, Lifei Zhu, Fubing Wu
Pages: 1559-1564
Published online on: 05 December 2018

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Article Open Access

MicroRNA‑885‑5p promotes osteosarcoma proliferation and migration by downregulation of cell division cycle protein 73 homolog expression

Feng‑Qiang Yu, Zeng Wang, Xin‑Wen Wang, Sheng‑Lin Wang, Xiao‑Dong Li, Qing‑Shan Huang, Jian‑Hua Lin
Pages: 1565-1572
Published online on: 06 December 2018

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Article Open Access

miR‑146a‑5p targets interleukin‑1 receptor‑associated kinase 1 to inhibit the growth, migration, and invasion of breast cancer cells

Jing‑Pei Long, Li‑Feng Dong, Fang‑Fang Chen, Yang‑Fan Fan
Pages: 1573-1580
Published online on: 28 November 2018

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Article Open Access

Design of a microfluidic chip consisting of micropillars and its use for the enrichment of nasopharyngeal cancer cells

Wen‑Xue Chen, Jin‑Gao Li, Xiang‑Hui Wan, Xue‑Sen Zou, Shu‑Yi Qi, Yu‑Qing Zhang, Qiu‑Min Weng, Jun‑Yu Li, Wen‑Min Xiong, Chen Xie, Wei‑Liang Cheng
Pages: 1581-1588
Published online on: 28 November 2018

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Article Open Access

Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy

Ailan Xian, Chunbin Wang, Ni Guo, Zaixing Wang, Lei Yang, Jie Gao, Longjun Yang
Pages: 1589-1594
Published online on: 06 December 2018

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Article Open Access

NOS1 upregulates ABCG2 expression contributing to DDP chemoresistance in ovarian cancer cells

Xiaoxuan Li, Zhiwei Zou, Jiao Tang, Youhong Zheng, Yu Liu, Yan Luo, Qiuzhen Liu, Yifeng Wang
Pages: 1595-1602
Published online on: 03 December 2018

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Article Open Access

Correlation analysis of IL‑4, IL‑10 and APN levels with postoperative infection of colorectal cancer

Jianyun He, Zhiyan Wang, Sihai Zhang
Pages: 1603-1608
Published online on: 06 December 2018

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Article Open Access

Apatinib enhances the radiosensitivity of the esophageal cancer cell line KYSE‑150 by inducing apoptosis and cell cycle redistribution

Lijun Hu, Fei Sun, Zhiqiang Sun, Xinchu Ni, Jian Wang, Jianlin Wang, Mengyun Zhou, Yue Feng, Ze Kong, Qiu Hua, Jingping Yu
Pages: 1609-1616
Published online on: 06 December 2018

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Article Open Access

SOX2 knockdown inhibits the migration and invasion of basal cell carcinoma cells by targeting the SRPK1‑mediated PI3K/AKT signaling pathway Retraction in /10.3892/ol.2024.14635

Zhuo‑Ran Li, Yong Jiang, Jian‑Zhong Hu, Yang Chen, Quan‑Zhong Liu
Pages: 1617-1625
Published online on: 07 December 2018

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Article Open Access

High PD‑L1 expression is associated with a favorable prognosis in patients with esophageal squamous cell carcinoma undergoing postoperative adjuvant radiotherapy

Chenxue Jiang, Yaoyao Zhu, Shuiqin Tang, Gu Zhang, Qingren Lin, Yaping Xu, Jinbiao Shang
Pages: 1626-1634
Published online on: 22 November 2018

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Article Open Access

Melatonin regulates tumor aggressiveness under acidosis condition in breast cancer cell lines

Nathália Martins Sonehara, Jéssica Zani Lacerda, Bruna Victorasso Jardim‑Perassi, Rubens de Paula Jr, Marina Gobbe Moschetta‑Pinheiro, Ynaiá Santos Traba Souza, Júlia Carolina Junqueira de Andrade, Debora Aparecida Pires de Campos Zuccari
Pages: 1635-1645
Published online on: 26 November 2018

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Article Open Access

Let‑7b acts as a tumor suppressor in osteosarcoma via targeting IGF1R

Kai Zhang, Weiwei Wang, Yi Liu, Aijun Guo, Donghui Yang
Pages: 1646-1654
Published online on: 04 December 2018

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Article Open Access

Efficacy and safety of consolidation chemotherapy during the resting period in patients with local advanced rectal cancer

Huan‑Qing Liang, Zhong‑Yi Dong, Zhi‑Jie Liu, Jiao Luo, Qin Zeng, Ping‑Yan Liao, De‑Hua Wu
Pages: 1655-1663
Published online on: 06 December 2018

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Article Open Access

MicroRNA‑504 modulates osteosarcoma cell chemoresistance to cisplatin by targeting p53

Xin Chen, Chen Lv, Xiongbai Zhu, Wenjun Lin, Lu Wang, Zhengxiang Huang, Shengwu Yang, Junying Sun
Pages: 1664-1674
Published online on: 22 November 2018

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Article Open Access

Determination of genetic aberrations and novel transcripts involved in the pathogenesis of oligodendroglioma using array comparative genomic hybridization and next generation sequencing

Siti A. Hassanudin, Stephen N. Ponnampalam, Muhammad N. Amini
Pages: 1675-1687
Published online on: 07 December 2018

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Article Open Access

Effects of claudin‑1 downregulation on the physiological processes of gallbladder cancer SGC996 cells

Hao Jin, Qiang Zhang, Shulong Zhang, Huichun Liu, Zhongran Man, Yong Wang
Pages: 1688-1694
Published online on: 21 November 2018

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Article Open Access

Oncogenic value of microRNA‑15b‑5p in hepatocellular carcinoma and a bioinformatics investigation

Wen‑Ya Pan, Jiang‑Hui Zeng, Dong‑Yue Wen, Jie‑Yu Wang, Peng‑Peng Wang, Gang Chen, Zhen‑Bo Feng
Pages: 1695-1713
Published online on: 22 November 2018

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Article Open Access

ACTG1 and TLR3 are biomarkers for alcohol‑associated hepatocellular carcinoma

Bing Gao, Shicheng Li, Zhen Tan, Leina Ma, Jia Liu
Pages: 1714-1722
Published online on: 26 November 2018

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Article Open Access

Expression and selective activation of somatostatin receptor subtypes induces cell cycle arrest in cancer cells

Yi Zou, Haiping Tan, Yuanfeng Zhao, Yuan Zhou, Lin Cao
Pages: 1723-1731
Published online on: 28 November 2018

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Article Open Access

MMP‑1 is overexpressed in triple‑negative breast cancer tissues and the knockdown of MMP‑1 expression inhibits tumor cell malignant behaviors in vitro

Qi‑Min Wang, Li Lv, Ying Tang, Li Zhang, Li‑Fen Wang
Pages: 1732-1740
Published online on: 30 November 2018

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Article Open Access

Transcriptome analysis of pancreatic cancer cell response to treatment with grape seed proanthocyanidins

Weihua Wang, Leilei Zhan, Dongqi Guo, Yanju Xiang, Yu Zhang, Muxing Tian, Zhanjiang Han
Pages: 1741-1749
Published online on: 06 December 2018

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Article Open Access

The efficacy and safety of bevacizumab in addition to platinum‑based chemotherapy for the first‑line treatment of patients with advanced nonsquamous non‑small‑cell lung cancer: Final results of AVALANCHE, an observational cohort study

Edina Tolnay, Áron Kristóf Ghimessy, Erzsébet Juhász, Zsuzsanna Sztancsik, György Losonczy, Péter Dombi, Zsuzsanna Vennes, László Helf, Edit Csada, Veronika Sárosi
Pages: 1750-1760
Published online on: 27 November 2018

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Article Open Access

Paeonol‑mediated apoptosis of hepatocellular carcinoma cells by NF‑κB pathway

Qiang Li, Ying Zhang, Jing Sun, Qiyu Bo
Pages: 1761-1767
Published online on: 19 November 2018

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Article Open Access

Expression of 3q oncogene SEC62 in atypical fibroxanthoma‑immunohistochemical analysis of 41 cases and correlation with clinical, viral and histopathologic features

Cornelia S.L. Müller, Léa Kreie, Florian Bochen, Thorsten Pfuhl, Sigrun Smola, Stefan Gräber, Thomas Vogt, Bernhard Schick, Maximilian Linxweiler
Pages: 1768-1776
Published online on: 27 November 2018

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Article Open Access

High ambient radiofrequency radiation in Stockholm city, Sweden

Michael Carlberg, Lena Hedendahl, Tarmo Koppel, Lennart Hardell
Pages: 1777-1783
Published online on: 03 December 2018

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Article Open Access

An atlas for clinical target volume definition, including elective nodal irradiation in definitive radiotherapy of biliary cancer

Silvia Bisello, Matteo Renzulli, Milly Buwenge, Lucia Calculli, Giuseppina Sallustio, Gabriella Macchia, Francesco Deodato, Giancarlo Mattiucci, Silvia Cammelli, Alessandra Arcelli, Lucia Giaccherini, Francesco Cellini, Giovanni Brandi, Sara Guerri, Savino Cilla, Rita Golfieri, Lorenzo Fuccio, Alessio G. Morganti, Alessandra Guido
Pages: 1784-1790
Published online on: 28 November 2018

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Article Open Access

Expression of miR-664 and miR-184 on proliferation, apoptosis and migration of osteosarcoma cells

Pengfei Tao, Jing Feng, Qiong Li, Wei Liu, Lin Yang, Xiaolong Zhao, Huan Ni, Ping Xia
Pages: 1791-1797
Published online on: 20 November 2018

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Article Open Access

Enhanced anticancer effect of oncostatin M combined with salinomycin in CD133+ HepG2 liver cancer cells

Changhao Fu, Lu Wang, Geer Tian, Chen Zhang, Yuanyuan Zhao, Hao Xu, Manman Su, Yi Wang
Pages: 1798-1806
Published online on: 05 December 2018

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Article Open Access

Analyses on K‑ras mutations and fascin expression in patients with cardia cancer

Li Wei, Haiyan Chang, Song Huo
Pages: 1807-1811
Published online on: 22 November 2018

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Article Open Access

Examination of the Biomark assay as an alternative to Oncotype DX for defining chemotherapy benefit

Jinkyoung Kim, Aeree Kim, Chungyeul Kim
Pages: 1812-1818
Published online on: 30 November 2018

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Article Open Access

miR‑7‑5p inhibits cell migration and invasion in glioblastoma through targeting SATB1

Chang‑You Yin, Wei Kong, Jing Jiang, Hao Xu, Wei Zhao
Pages: 1819-1825
Published online on: 28 November 2018

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Article Open Access

MMP-2 expression and correlation with pathology and MRI of glioma

Hui Zhang, Yunxia Ma, Haibao Wang, Liyan Xu, Yongqiang Yu
Pages: 1826-1832
Published online on: 06 December 2018

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Article

Clinical features and prognosis of breast cancer with gastric metastasis

Joohyun Hong, Youjin Kim, Jangho Cho, Sung Won Lim, Song Ee Park, Hee Kyung Kim, Hansang Lee, Soo Youn Cho, Ji‑Yeon Kim, Jin Seok Ahn, Young‑Hyuck Im, Yeon Hee Park
Pages: 1833-1841
Published online on: 23 November 2018

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Article

Impact of primary tumor location as a predictive factor in patients suffering from colorectal cancer treated with cytotoxic anticancer agents based on the collagen gel droplet‑embedded drug sensitivity test

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Akinori Nakatani, Kiichi Nagayasu, Naoki Sakuyama, Tsuyoshi Sato, Kenji Kishine, Yu Abe, Isao Nagaoka
Pages: 1842-1850
Published online on: 06 December 2018

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Article

Pemetrexed exerts anticancer effects by inducing G0/G1‑phase cell cycle arrest and activating the NOXA/Mcl‑1 axis in human esophageal squamous cell carcinoma cells

Xinying Li, Hongxia Song, Feng Kong, Yanxia Guo, Yuan Chen, Lu Zhang, Dongfang Gao, Xiaofei Zhao, Han Zhang
Pages: 1851-1858
Published online on: 23 November 2018

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Article

Decreased expression of ZO‑1 is associated with tumor metastases in liver cancer

Xueli Zhang, Liang Wang, Haitao Zhang, Fang Tu, Yong Qiang, Cuifang Nie
Pages: 1859-1864
Published online on: 27 November 2018

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Article

Overexpression of the ASPM gene is associated with aggressiveness and poor outcome in bladder cancer

Zhenglin Xu, Qi Zhang, Frank Luh, Baiye Jin, Xiyong Liu
Pages: 1865-1876
Published online on: 26 November 2018

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Article

Ophiopogonin D inhibits cell proliferation and induces apoptosis of human laryngocarcinoma through downregulation of cyclin B1 and MMP‑9 and upregulation of p38‑MAPK signaling

Zhiyu Yan, Guang Liu, Min Liang, Yanjun Xu
Pages: 1877-1882
Published online on: 03 December 2018

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Article

Caution for simple sequence repeat number variation in the mitochondrial DNA D‑loop to determine cancer‑specific variants

Tokiko Nakai, Akihisa Sakurada, Toshihide Endo, Hiroko Kobayashi, Shinobu Masuda, Makoto Makishima, Mariko Esumi
Pages: 1883-1888
Published online on: 07 December 2018

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Xian Zhang, Yong Zhou, Ying‑Er Gu
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Yingchun Li, Huihan Wang, Rong Zhang, Guojun Zhang, Ying Yang, Zhuogang Liu
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JTC‑801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3‑kinase/protein kinase B signalling pathway

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Association of the invasiveness of colon cancer with the expression of C/EBPα

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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