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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-2020 Volume 20 Issue 5

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Article Open Access

The c‑Jun signaling pathway has a protective effect on nucleus pulposus cells in patients with intervertebral disc degeneration

Ming Lei, Kun Wang, Shuai Li, Kangcheng Zhao, Wenbin Hua, Xinghuo Wu, Cao Yang
Article Number: 123
Published online on: 21 September 2020

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Article Open Access

GSK‑3β mediates the effects of HNF‑1β overexpression in ovarian clear cell carcinoma

Naoki Kawahara, Ayano Mizutani, Sho Matsubara, Yoshinori Takeda, Hiroshi Kobayashi
Article Number: 122
Published online on: 21 September 2020

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Article

Enhanced expression of synoviolin in peripheral blood from obese/overweight donors

Hidetoshi Fujita, Satoko Aratani, Izuru Mizoguchi, Naoko Yagishita, Toshihiro Nakajima
Article Number: 121
Published online on: 21 September 2020

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Article

Clinical investigation of acute myocardial infarction according to age subsets

Jianwei Wang, Li Li, Ning Ma, Xiaohui Zhang, Yanyan  Qiao, Guangjie Fang, Guoping Li, Tao Zhong
Article Number: 120
Published online on: 21 September 2020

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Article Open Access

Association between α1‑antitrypsin and acute coronary syndrome

Yan Liu, Da Huang, Beilin Li, Wenjing Liu, Suren R. Sooranna, Xingshou Pan, Zhaohe Huang, Jun Guo
Article Number: 119
Published online on: 21 September 2020

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Case Report Open Access

Primary carnitine deficiency in two sisters with intractable epilepsy and reversible metabolic cardiomyopathy: Two case reports

Xiu-Fang Yang, Guo-Sheng Liu, Bing Yi
Article Number: 118
Published online on: 21 September 2020

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Article Open Access

Irbesartan ameliorates myocardial fibrosis in diabetic cardiomyopathy rats by inhibiting the TGFβ1/Smad2/3 pathway

Min Zong, Hua Zhao, Qiang Li, Yanbing Li, Jianjun Zhang
Article Number: 117
Published online on: 18 September 2020

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Article Open Access

Brilliant blue G attenuates neuro‑inflammation via regulating MAPKs and NF‑κB signaling pathways in lipopolysaccharide‑induced BV2 microglia cells

Wei Wang, Feiran Huang, Weifeng Jiang, Weiwei Wang, Jie Xiang
Article Number: 116
Published online on: 18 September 2020

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Article

Role of TLR4/MyD88/NF‑κB signaling in the contrast‑induced injury of renal tubular epithelial cells

Xin Wang, Jiaojiao Zhou, Jia Yang, Siwen Wang, Lichuan Yang
Article Number: 115
Published online on: 18 September 2020

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Review

Effect of endometrioma and its surgical excision on fertility (Review)

Danni Jiang, Xiaocui Nie
Article Number: 114
Published online on: 18 September 2020

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Article Open Access

Tac2‑N serves an oncogenic role and promotes drug resistance in human gastric cancer cells

Lei Shen, Pingping Zhang, Jianbing Wang, Peng Ji
Article Number: 113
Published online on: 18 September 2020

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Article Open Access

Pretreatment with human urine‑derived stem cells protects neurological function in rats following cardiopulmonary resuscitation after cardiac arrest

Chun Pan, Xu Zheng, Liang Wang, Qian Chen, Qi Lin
Article Number: 112
Published online on: 18 September 2020

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Article Open Access

Aldh2 gene reduces oxidative stress in the bladder by regulating the NF‑κB pathway in a mouse model of ketamine‑induced cystitis

Xiao Jian Xi, Shao Hua Chen, Hua Mi
Article Number: 111
Published online on: 18 September 2020

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Article Open Access

SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway

Quan Du, Juan Chen
Article Number: 110
Published online on: 18 September 2020

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Article Open Access

Lithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia‑reperfusion mouse model

Yining Xiao, Mingyue Fan, Wei Jin, William A. Li, Yanqiu Jia, Yanhong Dong, Xin Jiang, Jing Xu, Nan Meng, Peiyuan Lv
Article Number: 109
Published online on: 18 September 2020

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Article Open Access

Effect of simultaneous surgical treatment in scoliosis associated with intraspinal abnormalities: A retrospective study

Kai Wang, Feng Shang, Feng-Zeng Jian, Hao Wu
Article Number: 108
Published online on: 18 September 2020

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Article Open Access

Evaluation of immune‑biomarker expression in high‑grade soft‑tissue sarcoma: HLA‑DQA1 expression as a prognostic marker

Jung Yun Bae, Kyung Un Choi, Ahrong Kim, So Jung Lee, Kyungbin Kim, Jee Yeon Kim, In Sook Lee, So Hak Chung, Jeung Il Kim
Article Number: 107
Published online on: 18 September 2020

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Article Open Access

Melatonin prevents the binding of vascular endothelial growth factor to its receptor and promotes the expression of extracellular matrix‑associated genes in nucleus pulposus cells

Chengchun Shen, Yan Li, Yunlin Chen, Lei Huang, Feng Zhang, Wei Wu
Article Number: 106
Published online on: 18 September 2020

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Article Open Access

Serum miRNA‑142 and BMP‑2 are markers of recovery following hip replacement surgery for femoral neck fracture

Haoyuan Gao, Xuyou Wang
Article Number: 105
Published online on: 18 September 2020

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Article Open Access

Clinical efficacy of γ‑globulin combined with dexamethasone and methylprednisolone, respectively, in the treatment of acute transverse myelitis and its effects on immune function and quality of life

Peiquan Wang, Suhua Zhang, Hongchun Lv, Gang Qiao, Xiaodong Zhong, Hua Li, Lili Zhang
Article Number: 104
Published online on: 18 September 2020

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Article

A novel frameshift mutation in the FERMT1 gene in a Chinese patient with Kindler syndrome

Li Meng, Xiaoqin Yang, Yuhao Wu, Zijun Zhao, Lianjuan  Yang, Ming Li, Xiuli Wang, Guolong Zhang
Article Number: 103
Published online on: 17 September 2020

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Article

Single‑nucleotide polymorphisms and haplotypes in the interleukin‑33 gene are associated with a risk of allergic rhinitis in the Chinese population

He Ran, Hua Xiao, Xing Zhou, Lijun Guo, Shuang Lu
Article Number: 102
Published online on: 17 September 2020

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Article Open Access

Prognostic value of serum hyponatremia for outcomes in patients with heart failure with preserved ejection fraction: An observational cohort study

Yang Su, Mengqiu Ma, Hengbin Zhang, Xin Pan, Xianling Zhang, Fenglei Zhang, Yangbo Lv, Chunxi Yan
Article Number: 101
Published online on: 17 September 2020

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Article Open Access

SFTPC genetic polymorphisms are associated with tuberculosis susceptibility and clinical phenotype in a Western Chinese Han population

Jun-Wei Zhao, Lin Jiao, Man-Man Guo, Lei Zheng, Xue-Bin Wang, Shu-Hui Gao, Bin-Wu Ying, Liang Ming
Article Number: 100
Published online on: 17 September 2020

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Article Open Access

Panax notoginseng saponins alleviates advanced glycation end product‑induced apoptosis by upregulating SIRT1 and antioxidant expression levels in HUVECs

Yang Bo, Zhang Jian, Sun Zhi‑Jun, Wu Quing, Zhao Hua, Li Chuan‑Wei, Cao Yu‑Kang
Article Number: 99
Published online on: 17 September 2020

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Article Open Access

Preoperative evaluation of dynamic contrast‑enhanced MRI‑guided lesion identification using morphometric and textural analysis for patients with epilepsy

Du Feizhou, Guan Jing, Wang Peng, Wu Jialing, Jiang Rui
Article Number: 98
Published online on: 17 September 2020

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Case Report Open Access

Novel compound variants of the TMTC3 gene cause cobblestone lissencephaly‑like syndrome: A case report

Guanghua Liu, Qing Zhou, Han Lin, Niu Li, Hong Ye, Jian Wang
Article Number: 97
Published online on: 16 September 2020

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Review Open Access

Circadian rhythm and atherosclerosis (Review)

Zaiqiang Zhang, Bin Yu, Xinan Wang, Caiyun Luo, Tian Zhou, Xiaxia Zheng, Jiawang Ding
Article Number: 96
Published online on: 16 September 2020

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Article

The clinical safety and efficacy of flexible bronchoscopy in a neonatal intensive care unit

Chongbing Yan, Yong Hu, Gang Qiu, Xiaohui Gong, Dermyshi Elda
Article Number: 95
Published online on: 16 September 2020

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Article Open Access

Effect of levocarnitine administration in patients with chronic liver disease

Kazuki Ohashi, Toru Ishikawa, Asami Hoshii, Tamaki Hokari, Mitsuyuki  Suzuki, Hirohito Noguchi, Hiroshi Hirosawa, Fujiko Koyama, Miki Kobayashi, Shiori  Hirosawa, Kaede Sugiyama, Yuta Mitobe, Toshiaki Yoshida
Article Number: 94
Published online on: 16 September 2020

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Case Report Open Access

Methimazole‑induced insulin autoimmune syndrome in Graves' disease with hypokalemia: A case report and literature review

Rongfeng Han, Xia Jiang
Article Number: 93
Published online on: 16 September 2020

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Article

lncRNA ZEB2‑AS1 stimulates cardiac hypertrophy by downregulating PTEN

Zhi Cheng, Lingyun Liu, Qingguo Li
Article Number: 92
Published online on: 16 September 2020

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Case Report Open Access

Gilbert syndrome with systemic lupus erythematosus presenting with persistent unconjugated hyperbilirubinemia: A case report

Naifang Ye, Zhuochao Zhou, Huiyun Gong, Jialing Teng, Yue Han, Chengde Yang, Junna Ye
Article Number: 91
Published online on: 14 September 2020

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Case Report Open Access

‘White cord syndrome’, a rare but disastrous complication of transient paralysis after posterior cervical decompression for severe cervical spondylotic myelopathy and spinal stenosis: A case report

Yu-Xin Liao, Shi-Sheng He, Zhi-Min He
Article Number: 90
Published online on: 11 September 2020

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Article Open Access

Use of polymyxin B in patients with renal impairment: A retrospective examination of 5 cases

Meiling Yu, Qi Zou, Huaxue Wang, Shengyong Zheng, Jian Xu, Ximing Deng, Chen Liu, Shibing Zhao, Xiandi He, Qiang Wu
Article Number: 89
Published online on: 11 September 2020

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Article Open Access

miR‑149‑5p inhibition reduces Alzheimer's disease β‑amyloid generation in 293/APPsw cells by upregulating H4K16ac via KAT8

Fuyan Chen, Huifeng Chen, Yujie Jia, Hai Lu, Qiaorui Tan, Xin Zhou
Article Number: 88
Published online on: 11 September 2020

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Article

Correlation of TNF‑α and IL‑10 gene polymorphisms with primary nephrotic syndrome

Min Xiao, Shoujun Bai, Jing Chen, Lijun Xie, Yaxi Li, Yongning Li, Shu Zhang, Yifan Wu, Gongjun Tan, Wenlian Wang, Yu Wang, Li Quan, Zhao Hu
Article Number: 87
Published online on: 11 September 2020

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Article Open Access

Diagnostic value of VDBP and miR‑155‑5p in diabetic nephropathy and the correlation with urinary microalbumin

Xu Bai, Qun Luo, Kuibi Tan, Liming Guo
Article Number: 86
Published online on: 11 September 2020

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Article Open Access

MicroRNA‑503‑5p improves carotid artery stenosis by inhibiting the proliferation of vascular smooth muscle cells

Zhiyuan Yan, Hong Wang, Junjun Liang, Yuan Li, Xiaodong Li
Article Number: 85
Published online on: 11 September 2020

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Article Open Access

Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation

Bing-Yi Shao, Lan Wang, Yang Yu, Liang Chen, Ning Gan, Wen-Ming Huang
Article Number: 84
Published online on: 11 September 2020

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Article Open Access

Oxidative stress is important in the pathogenesis of stress‑related mucosal disease

Xiaohong Wang, Qin Zhao, Huanling Shi, Feng Qi, Na Shi, Dongfang Bai, Xiaopei Li, Haipeng Yuan, Xiuli Zuo
Article Number: 83
Published online on: 11 September 2020

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Article Open Access

The compound 2‑benzylthio‑5,8‑dimethoxynaphthalene‑1,4‑dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in Ras‑mutated liver cancer cells

Gui-Nan Shen, Jing Li, Ying-Hua Jin, Hu-Nan Sun, Ying-Ying Hao, Mei-Hua Jin, Ren Liu, Wei-Long Li, Yong-Qing Zhang, Jia-Bin Yu, Nan-Nan Yu, Wei-Dong Wang, Li-Yun Yu, Ji-Su Kim, Taeho Kwon, Ying-Hao Han
Article Number: 82
Published online on: 11 September 2020

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Article Open Access

Osteogenic differentiation and inflammatory response of recombinant human bone morphogenetic protein‑2 in human maxillary sinus membrane‑derived cells

Jeewan Chun, Junho Jung, Jae-Hyung Lee, Sang-Hwan Oh, Yong-Dae Kwon
Article Number: 81
Published online on: 11 September 2020

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Article Open Access

Caduet enhances connexin 43 phosphorylation in left ventricular and thoracic aorta of SH model rats

Xiaoyan Huang, Junlu Yang, Baoguo Song, Nana Wang, Meijuan Ma, Haifang Wang, Sha Wang, Shuangping Hao, Gong Cheng
Article Number: 80
Published online on: 11 September 2020

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Article Open Access

Bone morphogenetic protein 2‑enhanced osteogenic differentiation of stem cell spheres by regulation of Runx2 expression

Sae Kyung Min, Minji Kim, Jun-Beom Park
Article Number: 79
Published online on: 11 September 2020

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Article Open Access

Advancing Covid‑19 differentiation with a robust preprocessing and integration of multi‑institutional open‑repository computer tomography datasets for deep learning analysis

Eleftherios Trivizakis, Nikos Tsiknakis, Evangelia E. Vassalou, Georgios Z. Papadakis, Demetrios A. Spandidos, Dimosthenis Sarigiannis, Aristidis Tsatsakis, Nikolaos Papanikolaou, Apostolos H. Karantanas, Kostas Marias
Article Number: 78
Published online on: 11 September 2020

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Article Open Access

SPAG5 is associated with unfavorable prognosis in patients with lung adenocarcinoma and promotes proliferation, motility and autophagy in A549 cells

Ruijia Huang, Aili Li
Article Number: 77
Published online on: 10 September 2020

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Article Open Access

Mechanisms of the lipopolysaccharide‑induced inflammatory response in alveolar epithelial cell/macrophage co‑culture

Jiansheng Li, Yanqin Qin, Yulong Chen, Peng Zhao, Xuefang Liu, Haoran Dong, Wanchun Zheng, Suxiang Feng, Xiaoning Mao, Congcong Li
Article Number: 76
Published online on: 10 September 2020

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Article Open Access

Comparison of pancreatic function and quality of life between patients with infected pancreatitis necrosis undergoing open necrosectomy and minimally invasive drainage: A long‑term study

Jianfeng Tu, Jingzhu Zhang, Yue Yang, Qiuran Xu, Lu  Ke, Zhihui Tong, Weiqin Li, Jieshou Li
Article Number: 75
Published online on: 10 September 2020

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Article Open Access

Isoflurane suppresses lung ischemia‑reperfusion injury by inactivating NF‑κB and inhibiting cell apoptosis

Ning Lv, Xiaoyun Li
Article Number: 74
Published online on: 10 September 2020

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Opinion Open Access

[Opinion] COVID‑19 pandemic: Monitoring space‑time data and learning from global experience

Emmanouil K. Symvoulakis, George Sourvinos, Demetrios A. Spandidos, Christos Lionis
Article Number: 73
Published online on: 10 September 2020

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Article Open Access

Paclitaxel inhibits the migration of CD133+ U251 malignant glioma cells by reducing the expression of glycolytic enzymes

Niya Long, Shuo Peng, Liangzhao Chu, Jun Jia, Minghao Dong, Jian Liu
Article Number: 72
Published online on: 09 September 2020

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Article Open Access

Hypertonic saline improves brain edema resulting from traumatic brain injury by suppressing the NF‑κB/IL‑1β signaling pathway and AQP4

Hui Zhang, Jun Liu, Yunzhen Liu, Chunhai Su, Gaoyang Fan, Wenpeng Lu, Lei Feng
Article Number: 71
Published online on: 09 September 2020

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Article Open Access

CGA ameliorates cognitive decline by regulating the PI3K/AKT signaling pathway and neurotransmitter systems in rats with multi-infarct dementia

Ying Fu, Jiangping Wei, Bin Li, Lijuan Gao, Peng Xia, Yueqiang Wen, Shijun Xu
Article Number: 70
Published online on: 09 September 2020

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Article

Overexpression of long non‑coding RNA nuclear enriched abundant transcript 1 inhibits the expression of p53 and improves premature ovarian failure

Manchao Li, Jintao Peng, Zhi Zeng
Article Number: 69
Published online on: 09 September 2020

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Article Open Access

miR‑376c‑3p modulates the properties of breast cancer stem cells by targeting RAB2A

Feng Zhao, Ming Zhong, Wenjiang Pei, Baoxing Tian, Yantao Cai
Article Number: 68
Published online on: 09 September 2020

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Article Open Access

Differential expression of peptides serves as an indicator of IgA nephropathy in pediatric patients

Chunbao Rao, Fan Yang, Zhijun Lai, Sujun Chen, Xiaomei Lu, Xiaoyun Jiang
Article Number: 67
Published online on: 09 September 2020

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Article Open Access

Stent retriever thrombectomy combined with long‑term local thrombolysis for severe hemorrhagic cerebral venous sinus thrombosis

Yihua Wang, Cuiping Zhao, Dezhang Huang, Bin Sun, Zhigang Wang
Article Number: 66
Published online on: 09 September 2020

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Article Open Access

circKMT2D contributes to H2O2‑attenuated osteosarcoma progression via the miR‑210/autophagy pathway

Jun Zhang, Xubin Chou, Ming Zhuang, Chenlei Zhu, Yong Hu, Dong Cheng, Zhiwei Liu
Article Number: 65
Published online on: 09 September 2020

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Article

Beneficial effect of black rice (Oryza sativa L. var. japonica) extract on amyloid β‑induced cognitive dysfunction in a mouse model

Ah Young Lee, Ji Myung Choi, Young A. Lee, Seon Hwa Shin, Eun Ju Cho
Article Number: 64
Published online on: 09 September 2020

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Article Open Access

Downregulation of miR‑27b promotes skin wound healing in a rat model of scald burn by promoting fibroblast proliferation

Qingxia Bi, Jingyan Liu, Xueming Wang, Furong Sun
Article Number: 63
Published online on: 04 September 2020

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Article Open Access

Polydatin prevents bleomycin‑induced pulmonary fibrosis by inhibiting the TGF‑β/Smad/ERK signaling pathway

Yan-Lu Liu, Bao-Yi Chen, Juan Nie, Guang-Hui Zhao, Jian-Yi Zhuo, Jie Yuan, Yu-Cui Li, Ling-Li Wang, Zhi-Wei Chen
Article Number: 62
Published online on: 04 September 2020

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Article

Left ventricular diastolic dysfunction is associated with cerebral infarction in young hypertensive patients: A retrospective case‑control study

Hui-Jun Wen, Xiao-Yong Wang
Article Number: 61
Published online on: 04 September 2020

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Article Open Access

In silico prediction and validation of potential therapeutic genes in pancreatic β‑cells associated with type 2 diabetes

Di Yi Zhou, Xin Mou, Kaiyuan Liu, Wen Hong Liu, Ya Qing Xu, Danyang Zhou
Article Number: 60
Published online on: 04 September 2020

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Article Open Access

Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects in rabbit knees through the transforming growth factor‑β superfamily signaling pathway

Chao Ye, Jing Chen, Yi Qu, Hang Liu, Junxing Yan, Yingdong Lu, Zheng Yang, Fengxian Wang, Pengyang Li
Article Number: 59
Published online on: 04 September 2020

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Article Open Access

Altered function of the left ventricle and clinical significance of heart‑type fatty acid‑binding protein in cardiac dysfunction among patients with sepsis

Guopeng Weng, Peigang Tian, Xiaojun Yan, Qinghong Cheng
Article Number: 58
Published online on: 04 September 2020

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In vitro effects of azide‑containing human CRP isoforms and oxLDL on U937‑derived macrophage production of atherosclerosis‑related cytokines

Dania Jundi, Imtissal Krayem, Samer Bazzi, Marc Karam
Article Number: 57
Published online on: 04 September 2020

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Associations between the concentrations of CD68, TGF‑β1, renal injury index and prognosis in glomerular diseases

Jingshu Sun, Lihai Hao, Hongbo Shi
Article Number: 56
Published online on: 04 September 2020

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miR‑590‑5p may regulate colorectal cancer cell viability and migration by targeting PDCD4 Corrigendum in /10.3892/etm.2024.12392

Ting Guo, Jun Wang, Guochang Cheng, He Huang
Article Number: 55
Published online on: 04 September 2020

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Effect and mechanism of asiatic acid on autophagy in myocardial ischemia‑reperfusion injury in vivo and in vitro

Chenlong Yi, Linjie Si, Jing Xu, Junyi Yang, Qiang Wang, Xiaowei Wang
Article Number: 54
Published online on: 04 September 2020

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MicroRNA‑23a acts as an oncogene in pancreatic carcinoma by targeting TFPI‑2

Wei Wang, Jin‑Zhuo Ning, Zhi‑Gang Tang, Ying He, Li-Chao Yao, Lin Ye, Lun Wu
Article Number: 53
Published online on: 04 September 2020

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Composite ammonium glycyrrhizin has hepatoprotective effects in chicken hepatocytes with lipopolysaccharide/enrofloxacin‑induced injury

Xuewen Guo, Wenyang Li, Ran An, Mei Huang, Zugong Yu
Article Number: 52
Published online on: 04 September 2020

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Diagnostic value of combination of cranial MRI, serum homocysteine and procalcitonin for hyperbilirubinemia complicated with brain injury in neonates

Na Chang, Guangbin Wang
Article Number: 51
Published online on: 03 September 2020

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Integrated Bioinformatics analysis and clinical validation reveals that high expression of mucin 1 in intrahepatic cholangiocarcinoma predicts recurrence after curative resection

Fei-Yu Chen, Cheng Zhou, Xiang-Yu Zhang, Kai-Qian Zhou, Yuan-Fei Peng, Lei Yu, Jia Fan, Jian Zhou, Jie Hu, Zheng Wang
Article Number: 50
Published online on: 03 September 2020

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IGF‑1 induces cellular senescence in rat articular chondrocytes via Akt pathway activation

Li-Dong Zhao, Lian-Yu Bie, Lan Hu, Zi-Han Zhu, Xing-Hua Meng, Lin-Lin Cong, Shai Zhang, Ning Ma, Jian-Hua Xiao
Article Number: 49
Published online on: 03 September 2020

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Changes in inflammation and oxidative stress signalling pathways in coarcted aorta triggered by bicuspid aortic valve and growth in young children

Katie L. Skeffington, Andrew R. Bond, M. Giulia Bigotti, Safa  Abdulghani, Dominga  Iacobazzi, Sok-Leng Kang, Kate   J. Heesom, Marieangela   C. Wilson, Serban  Stoica, Robin Martin, Massimo  Caputo, M. Saadeh Suleiman, Mohamed T. Ghorbel
Article Number: 48
Published online on: 03 September 2020

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Helicobacter pylori is associated with weakened pulmonary function and reduced incidence of allergic conditions in patients with chronic cough

Meng He, Yuanyuan Zheng, A'huo Ma, Chunyi Zhang, Yuefang Yu, Hua Wang, Yefeng Chen, Min Xiang, Kelong Tao, Juxin Shen
Article Number: 47
Published online on: 03 September 2020

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Caffeine versus aminophylline in combination with oxygen therapy for apnea of prematurity: A retrospective cohort study

Cheng-Yun Zhang, Dong‑Jie Liu, Shao-Dong Hua, Shan  Guo, Xiao-Yan Li, Bing Zhang, Li-Hua An
Article Number: 46
Published online on: 03 September 2020

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Non‑cytotoxic doses of shikonin inhibit lipopolysaccharide‑induced TNF‑α expression via activation of the AMP‑activated protein kinase signaling pathway

Fang Zhang, Tao Pan, Xiaohui Wu, Xingchun Gao, Zhikui Li, Xinling Ren
Article Number: 45
Published online on: 03 September 2020

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Expression of Rab1A in bladder cancer and its clinical implications

Hongwei Su, Ting Li, Chen Li, Xin Liu, Haibin Ling, Xiangdong Li
Article Number: 44
Published online on: 03 September 2020

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Fetal thymus in the middle and late trimesters: Morphometry and development using post‑mortem 3.0T MRI

Leilei Yuan, Jinfeng Cao, Zhaohua Wang, Litao Zhang, Xia  Wang, Yong Wu, Jinye Dong, Huihui Xie, Xiangtao Lin
Article Number: 43
Published online on: 03 September 2020

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Comparison of acute kidney injury with radial vs. femoral access for patients undergoing coronary catheterization: An updated meta‑analysis of 46,816 patients

Chang Wang, Weiwei Chen, Ming Yu, Ping Yang
Article Number: 42
Published online on: 02 September 2020

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Pharmaceutical inhibition of AXL suppresses tumor growth and invasion of esophageal squamous cell carcinoma

Sha Han, Yequan Wang, Chengyan Ge, Mingtao Gao, Xintong Wang, Feiyu Wang, Lei Sun, Sheng Li, Tingting Dong, Zhen Dang, Wen Cui, Guoan Zhang, Ning Liu
Article Number: 41
Published online on: 02 September 2020

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Changes in intestinal flora in patients with type 2 diabetes on a low‑fat diet during 6 months of follow‑up

Chengguo Liu, Wei Shao, Ming Gao, Jinyao Liu, Qiongyao Guo, Jie Jin, Fei Meng
Article Number: 40
Published online on: 01 September 2020

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Japanese patients with mitochondrial 3‑hydroxy‑3‑methylglutaryl‑CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations

Yasuhiko Ago, Hiroki Otsuka, Hideo Sasai, Elsayed Abdelkreem, Mina Nakama, Yuka Aoyama, Hideki Matsumoto, Ryoji Fujiki, Osamu Ohara, Kazumasa Akiyama, Kaori Fukui, Yoriko Watanabe, Yoko Nakajima, Hidenori Ohnishi, Tetsuya Ito, Toshiyuki Fukao
Article Number: 39
Published online on: 01 September 2020

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MicroRNA-146a downregulates the production of hyaluronic acid and collagen I in Graves' ophthalmopathy orbital fibroblasts

Wei Liu, Chao Ma, Hao-Yu Li, Lan Chen, Shan-Si Yuan, Kai-Jun Li
Article Number: 38
Published online on: 01 September 2020

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Clinical efficacy of coil embolization in treating pseudoaneurysm post‑Whipple operation

Hao Xu, Cong Jing, Jie Zhou, Xuli Min, Jing Zhao, Lin Yang, Yongjun Ren
Article Number: 37
Published online on: 01 September 2020

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A systematic review of non‑pharmacological interventions used for pain relief after orthopedic surgical procedures

Meifen Fan, Zheying Chen
Article Number: 36
Published online on: 01 September 2020

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Epigenetic modulation of the MAPK pathway prevents isoflurane‑induced neuronal apoptosis and cognitive decline in aged rats

Lei Huang, Hai‑Bin Fang, Hui‑Hui Cheng, Sheng‑Lan Mei, Yun‑Ping Cheng, Yao Lv, Qing-Tao Meng, Zhong‑Yuan Xia
Article Number: 35
Published online on: 01 September 2020

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Gene expression profiling of sepsis‑associated acute kidney injury

Jing-Juan Yang, Bin‑Bin Wu, Fei Han, Jiang-Hua Chen, Yi Yang
Article Number: 34
Published online on: 01 September 2020

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EZH2 regulates sFRP4 expression without affecting the methylation of sFRP4 promoter DNA in colorectal cancer cell lines

Yuting Liu, Jun Yu, Yang Xie, Mengying Li, Feng Wang, Jing Zhang, Jian Qi
Article Number: 33
Published online on: 01 September 2020

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Long non‑coding RNA Mirt2 interacts with long non‑coding RNA IFNG‑AS1 to regulate ulcerative colitis

Chenyang Li, Lujia Cui, Siqiong Li, Minrui Li, Xinpu Miao
Article Number: 32
Published online on: 01 September 2020

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Comparative observation of the efficacy of simplified Descemet stripping endothelial keratoplasty and penetrating keratoplasty in treating bullous keratopathy

Yingxin Chen, Shanshan Sun, Minghong Gao, Qiming Liu, Ziyue Wang
Article Number: 31
Published online on: 01 September 2020

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[Retracted] Hospital information technology in home care (Review)

Xiao-Ying Zhang, Pei-Ying Zhang
Article Number: 30
Published online on: 01 September 2020

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Effects of intra‑articular pulsed radiofrequency current administration on a rabbit model of rheumatoid arthritis

Hee Kyung Cho, Gi-Young Park, Woo Jung Sung, Sang Gyu Kawk, Won Bin Jung
Article Number: 29
Published online on: 31 August 2020

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Experimental induction of blunt chest trauma in mice: A modified approach with evaluation in dummies and cadavers

Denis Höfer, Christina Körbel, Matthias W. Laschke, Nils T. Veith, Tim Pohlemann, Reinhard Kappl, Thomas Tschernig
Article Number: 28
Published online on: 31 August 2020

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Adult liver transplantation using pediatric donor livers after cardiac or brain death: A report of three cases

Limin Ding, Lishan Deng, Xinchang Li, Zhidan Xu
Article Number: 27
Published online on: 31 August 2020

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Abnormal metabolic processes involved in the pathogenesis of non‑alcoholic fatty liver disease (Review)

Mingmei Shao, Zixiang Ye, Yanhong Qin, Tao Wu
Article Number: 26
Published online on: 28 August 2020

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Comparison of the clinical efficacy of AcrySof® IQ and TECNIS® toric intraocular lenses: A real‑world study

Juan-Juan Yang, Ya-Zhou Qin, Li Qin, Jing-Ming Li
Article Number: 25
Published online on: 28 August 2020

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Comparison of the effectiveness and safety of travoprost and latanoprost for the management of open‑angle glaucoma given as an evening dose

Jing Li, Xiaoyi Wang, Guihua Xu, Ruidong Deng, Laiwei Wu, Liqin Zhang, Zilin Chen
Article Number: 24
Published online on: 28 August 2020

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Efficacy of procaine combined with ketamine and propofol in pediatric epidural anesthesia

Hai Huang, Yujie Liu, Zijun Gao, Xucai Wu
Article Number: 23
Published online on: 28 August 2020

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Mesenchymal stem cells regulate inflammatory milieu within degenerative nucleus pulposus cells via p38 MAPK pathway

Yuanting Zhao, Yue Qin, Shufang Wu, Dageng Huang, Huimin Hu, Xinliang Zhang, Dingjun Hao
Article Number: 22
Published online on: 27 August 2020

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Expression, epitope prediction and IgE‑binding of the Tyrophagus putrescentiae group 13 allergen

Nan Wang, Ying Zhou, Meili Wu, Hanting Zhu, Yubao Cui
Article Number: 21
Published online on: 27 August 2020

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Role of electrocardiograms in assessment of severity and analysis of the characteristics of ST elevation in acute myocarditis: A two‑centre study

Jiaozhen Chen, Shouquan Chen, Zhangping Li, Peisen Zhou, Weijia Huang, Hete Wang, Jincun Shi, Yunchao Ni, Lili Lin, Yuanli Lei
Article Number: 20
Published online on: 27 August 2020

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Combined culture experiment of mouse bone marrow mesenchymal stem cells and bioceramic scaffolds

Xin Huang, Zhenhao Chen, Guanglei Zhao, Jingsheng Shi, Gangyong Huang, Feiyan Chen, Yibing Wei, Jun Xia, Jie Chen, Siqun Wang
Article Number: 19
Published online on: 27 August 2020

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Combined effect of recombinant human adenovirus p53 and curcumin in the treatment of liver cancer

Juan Qu, Wei Lu, Ming Chen, Wei Gao, Cong Zhang, Bin Guo, Jizhi Yang
Article Number: 18
Published online on: 26 August 2020

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Metformin attenuates renal interstitial fibrosis through upregulation of Deptor in unilateral ureteral obstruction in rats

Yanxia Wang, Yan Wang, Yong Li, Linghong Lu, Yingxian Peng, Shu Zhang, Anzhou Xia
Article Number: 17
Published online on: 26 August 2020

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Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell‑derived neurotrophic factor expression

Yee Lian Tiong, Khuen Yen Ng, Rhun Yian Koh, Gnanajothy Ponnudurai, Soi Moi Chye
Article Number: 16
Published online on: 26 August 2020

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Aberrant expression of miR‑4728 in patients with non‑small cell lung cancer and its regulatory effects on tumor progression in tumor cells

Ying Hu, Xinfang Zhang, Cuixue Gong, Jianzhao Li
Article Number: 15
Published online on: 26 August 2020

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A novel monoclonal antibody against human B7‑1 protects against chronic graft‑vs.‑host disease in a murine lupus nephritis model

Lijun Shen, Ying Zhu, Lianhua Han, Yuyu Wang, Tianming Yan, Yong Kong, Shitao Zou, Yuhua Qiu, Yan Xu
Article Number: 14
Published online on: 25 August 2020

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Molecular diagnosis of COVID‑19: Current situation and trend in China (Review)

Ning Li, Pengtao Wang, Xinyue Wang, Chenhao Geng, Jiale Chen, Yanhua Gong
Article Number: 13
Published online on: 25 August 2020

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[Corrigendum] Nebulized step‑down budesonide vs. fluticasone in infantile asthma: A retrospective cohort study

Zhimin Wu, Xiangli Bian, Lei Hui, Jinping Zhang
Article Number: 12
Published online on: 25 August 2020

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SMYD3 promotes colon adenocarcinoma (COAD) progression by mediating cell proliferation and apoptosis

Fu‑Ren Yue, Zhi‑Bin Wei, Rui‑Zhen Yan, Qiu‑Hong Guo, Bing Liu, Jing‑Hui Zhang, Zheng Li
Article Number: 11
Published online on: 25 August 2020

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Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate‑induced colitis

Miao Liu, Wenjie Xie, Xinyue Wan, Tao Deng
Article Number: 10
Published online on: 25 August 2020

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Downregulation of microRNA‑320a inhibits proliferation and induces apoptosis of retinoblastoma cells via targeting TUSC3

Li Kong, Yang Sun, Maosheng Chen, Yan Dai, Zhen Liu
Article Number: 9
Published online on: 25 August 2020

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Advances in Ca2+ modulation of gastrointestinal anion secretion and its dysregulation in digestive disorders (Review)

Weixi Shan, Yanxia Hu, Jianhong Ding, Xiaoxu Yang, Jun Lou, Qian Du, Qiushi Liao, Lihong Luo, Jingyu Xu, Rui Xie
Article Number: 8
Published online on: 25 August 2020

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UBR5 oncogene as an indicator of poor prognosis in gastric cancer

Fanghui Ding, Xiaoliang Zhu, Xiaojing Song, Pei Yuan, Longfei  Ren, Changpeng Chai, Wence Zhou, Xun Li
Article Number: 7
Published online on: 25 August 2020

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Reflectance confocal microscopy characteristics of oral lichen planus: An analysis of 47 cases in a Chinese cohort

Hao Peng, Yufeng Wang, Lingyue Shen, Guoyu Zhou
Article Number: 6
Published online on: 25 August 2020

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Mechanical stretch and LPS affect the proliferation, extracellular matrix remodeling and viscoelasticity of lung fibroblasts

Yongpeng Xie, Ying Qian, Yanli Wang, Kexi Liu, Xiaomin Li
Article Number: 5
Published online on: 25 August 2020

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The role of reactive oxygen species in cognitive impairment associated with sleep apnea

Linhao Xu, Yibo Yang, Jian Chen
Article Number: 4
Published online on: 25 August 2020

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Protective effect and mechanism of microRNA‑146a on ankle fracture

Haijun Mao, Guangyue Xu
Article Number: 3
Published online on: 25 August 2020

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Role of microRNA‑15a‑5p/TNFAIP3‑interacting protein 2 axis in acute lung injury induced by traumatic hemorrhagic shock

Feng Zhou, Zhizhen Liu, Huazhong Cai, Zhenjun Miao, Faxing Wei, Chao Song
Article Number: 2
Published online on: 25 August 2020

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[Retracted] The correlation between microvessel pathological changes of the endplate and degeneration of the intervertebral disc in diabetic rats

Sen Chen, Meimei Liao, Jianping Li, Hao Peng, Min Xiong
Article Number: 1
Published online on: 21 August 2020

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September-2026 Volume 32 Issue 3

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A prospective study of non‑invasive preimplantation genetic testing for Rh status, sex prediction and mtDNA copy number analysis using ddPCR on spent culture media

Ece Gumusoglu‑Acar, Sude Subasi, Merve Cebeci, Zehranur Sisman, Ecenur Karadisogullari, Burcin Karamustafaoglu‑Balci, Hale Goksever‑Celik, Ercan Bastu, Faruk Buyru, Tuba Gunel
Article Number: 251
Published online on: 20 July 2026

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m6A methylation regulatory network in pulmonary fibrosis: Molecular mechanisms from RNA stability to cellular phenotype transition (Review)

Lielong Mao, Dekun Zhou, Guoqi Zhou, Xiaofeng Lu
Article Number: 250
Published online on: 20 July 2026

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[Retracted] Dapagliflozin can alleviate renal fibrosis in rats with streptozotocin‑induced type 2 diabetes mellitus

Song Xue, Ying-Xuan Li, Xiao-Xiao Lu, Wei Tang
Article Number: 249
Published online on: 20 July 2026

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Ubiquitin‑driven regulation of immune checkpoints in lung cancer: Mechanisms and therapeutic implications (Review)

Lin Chai, Lin-Rong Pang, Yi-Ting Li, Jia-Hui Wang, Jun Chen, Zu-Guo Yuan, Xiao-Feng Jin
Article Number: 248
Published online on: 15 July 2026

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Case Report

Severe delayed diaphragmatic hernia with total gastric migration after cytoreductive surgery, a rare complication: A case report

Marine Stouvenel, Houssein El Hajj, Patricia Pautier, Philippe Morice, Sébastien Gouy
Article Number: 247
Published online on: 15 July 2026

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[Retracted] An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure  

Mei Gao, Jiangrong Wang, Zhongsu Wang, Yong Zhang, Hui Sun, Xinxing Xie, Yinglong Hou
Article Number: 246
Published online on: 13 July 2026

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Angiomatous meningioma with cystic degeneration: A case report

Zetong Bai, Yaojun Song, Haiguang Liu, Yan Wang, Shian Yin, Xichao Wen, Haipeng Liu, Jiayu Chen, Haipeng Xie, Zhaomu Zeng
Article Number: 245
Published online on: 10 July 2026

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Mitochondrial autophagy promotion contributes to the protective effects of BYHWD glycoside‑enriched fraction against OGD/R‑induced injury in H9C2 cells

Xujiao Hu, Jingjing Fang, Tong Sun, Jiheng Feng, Fangmei Zhou, Mingyuan Zhou, Zhishan Ding
Article Number: 244
Published online on: 09 July 2026

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[Corrigendum] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Article Number: 243
Published online on: 08 July 2026

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A rare spinal cord infarction caused by aortic mural thrombosis in a patient with cancer and the associated diagnostic challenges due to it mimicking spinal cord compression: A case report

Nobuhito Hara, Shunsuke Okazaki, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Masaki Kobayashi, Hitoshi Nakagawa, Mako Iwata, Toshiteru Miyasaka, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 242
Published online on: 07 July 2026

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Occupational exposure to freshwater crustaceans as a route of paragonimiasis presenting with eosinophilic pleural effusion misdiagnosed as tuberculous pleurisy: A case report and literature review

Xin Li, Peng Wang, Dan Cheng, Xiaoqin Peng, Lu Xue, Jiankun Wang, Jun Li
Article Number: 241
Published online on: 07 July 2026

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[Retracted] Downregulation of miR‑183 inhibits the growth of PANC‑1 pancreatic cancer cells in vitro and in vivo, and increases chemosensitivity to 5‑fluorouracil and gemcitabine  

Xiaoping Yang, Wei Wang, Xiong Zhang, Qi Zou, Lei Cai, Bo Yu
Article Number: 240
Published online on: 07 July 2026

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Case Report

Stepwise endoscopic and surgical management of spontaneous esophageal rupture with severe mediastinal contamination: A case report

Yan Zhang, Yuan Yao, Jing Cao, Ning Zhong
Article Number: 239
Published online on: 06 July 2026

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Kidney organoids as models for hereditary kidney diseases: Toward precision medicine (Review)

Sheng Cui, Tianlei Chen, Yun Zou, Min Li, Hua Zhou, Jingting Jiang, Min Yang
Article Number: 238
Published online on: 06 July 2026

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Role of fine‑needle aspiration cytology and cell morphology in determining the histogenesis of salivary gland lesions

Bisharah Soudah, Mahmoud Abbas
Article Number: 237
Published online on: 06 July 2026

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Risk factors associated with treatment failure in peritoneal dialysis‑associated peritonitis

Yao Jiang, Xiaoyan Luo, Tao Peng, Yang Li
Article Number: 236
Published online on: 06 July 2026

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Role and insights of human papillomavirus E5 oncoprotein in cervical carcinogenesis

Jyoti Rani, Sandeep Sisodiya, Kapil Kumar, Sandeep Kumar, Asiya Khan, Ekta Gupta, Showket Hussain
Article Number: 235
Published online on: 06 July 2026

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Case Report Open Access

Total knee arthroplasty for the treatment of osteoarthritis secondary to bilateral congenital patellar dislocation: A case report and review of the literature

Haishan Lin, Ding Yang, Xuming Ding, Xingjia Yang, Yaohua Wang
Article Number: 234
Published online on: 06 July 2026

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Research progress of lactylation modification in tumors (Review)

Shi-Chao Fang, Zhi-Zhou Shi
Article Number: 233
Published online on: 06 July 2026

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[Retracted] Resveratrol attenuates type 2 diabetes mellitus by mediating mitochondrial biogenesis and lipid metabolism via Sirtuin type 1

Ming-Ming Cao, Xi Lu, Guo-Dong Liu, Ying Su, Yan-Bo Li, Jin Zhou
Article Number: 232
Published online on: 01 July 2026

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Clinical differentiation between pediatric pulmonary tuberculosis and Mycoplasma pneumoniae pneumonia (Review)

Zong Wan, Renjie Qi, Qiushi Yang, Huan Li, Shusong Ruan
Article Number: 231
Published online on: 30 June 2026

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October-2026 Volume 32 Issue 4

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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
Article Number: 254
Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
Article Number: 253
Published online on: 24 July 2026

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[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Article Number: 252
Published online on: 23 July 2026

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