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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2017 Volume 14 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

The role of eukaryotic translation initiation factor 6 in tumors (Review)

Wei Zhu, Gui Xian Li, Hong Lang Chen, Xing Yan Liu
Pages: 3-9
Published online on: 12 May 2017

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Review Open Access

Pediatric haematopoiesis and related malignancies (Review) Corrigendum in /10.3892/ol.2021.12853

Mingwei Jin, Shumei Xu, Qi An
Pages: 10-14
Published online on: 28 April 2017

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Article Open Access

Identification of anti‑tumor components from toad venom

Fei Gao, Xiangjun Wang, Zhao Li, Aicun Zhou, Evelyn Tiffany‑Castiglioni, Lijun Xie, Yongchang Qian
Pages: 15-22
Published online on: 12 May 2017

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Article Open Access

Novel association of MEN1 gene mutations with parathyroid carcinoma

Luigia Cinque, Angelo Sparaneo, Filomena Cetani, Michelina Coco, Celeste Clemente, Massimiliano Chetta, Teresa Balsamo, Claudia Battista, Eliana Sanpaolo, Elena Pardi, Leonardo D'Agruma, Claudio Marcocci, Evaristo Maiello, Geoffrey N. Hendy, David E.C. Cole, Alfredo Scillitani, Vito Guarnieri
Pages: 23-30
Published online on: 12 May 2017

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Case Report Open Access

Metastases of transverse colon cancer to bilateral ovaries (Krukenberg tumor) and the left breast: A case report

Xin‑Yu Luo, Jue Wang, Jia Zhao, Rui Chen, Xiao‑Ming Zha
Pages: 31-34
Published online on: 11 May 2017

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Article Open Access

Expression of 4-hydroxynonenal in esophageal squamous cell carcinoma

Ying Zhang, Hu Wang, Kezhou Wu, Zhaoyong Liu
Pages: 35-40
Published online on: 05 May 2017

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Article Open Access

Overexpression of the X-linked ribosomal protein S4 predicts poor prognosis in patients with intrahepatic cholangiocarcinoma

Jie Kuang, Qin‑Yu Li, Fei Fan, Ning‑Jia Shen, Yong‑Jie Zhan, Zhao‑Hui Tang, Wen‑Long Yu
Pages: 41-46
Published online on: 08 May 2017

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Article Open Access

Prevalence and clinical significance of mediator complex subunit 12 mutations in 362 Han Chinese samples with uterine leiomyoma

Juan Wu, Yang Zou, Yong Luo, Jiu‑Bai Guo, Fa‑Ying Liu, Jiang‑Yan Zhou, Zi‑Yu Zhang, Lei Wan, Ou‑Ping Huang
Pages: 47-54
Published online on: 04 May 2017

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Article Open Access

C59T mutation in exon 2 of monocytic leukemia‑associated antigen‑34 gene indicates a high risk of recurrence of acute myeloid leukemia

Bo Lei, Yinxia Chen, Aili He, Jing Luo, Pengyu Zhang, Fuling Zhou, Jie Liu, Xin Meng, Jing Wang, Wanggang Zhang
Pages: 55-62
Published online on: 02 May 2017

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Article Open Access

Overexpression of sphingosine kinase 1 is predictive of poor prognosis in human breast cancer

Ya‑Jing Zhu, Hua You, Jin‑Xiang Tan, Fan Li, Zhu Qiu, Hong‑Zhong Li, Hong‑Yan Huang, Ke Zheng, Guo‑Sheng Ren
Pages: 63-72
Published online on: 08 May 2017

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Article Open Access

Treatment outcome analysis of chemotherapy combined with modulated electro-hyperthermia compared with chemotherapy alone for recurrent cervical cancer, following irradiation

Sun Young Lee, Na Ri Lee, Dong‑Hyu Cho, Jung Soo Kim
Pages: 73-78
Published online on: 04 May 2017

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Article Open Access

Mammographic calcification can predict outcome in women with breast cancer treated with breast-conserving surgery

Xiaomin Qi, Aoxiang Chen, Pei Zhang, Wei Zhang, Xuchen Cao, Chunhua Xiao
Pages: 79-88
Published online on: 03 May 2017

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Article Open Access

Azithromycin effectively inhibits tumor angiogenesis by suppressing vascular endothelial growth factor receptor 2‑mediated signaling pathways in lung cancer

Fajiu Li, Jie Huang, Dongyuan Ji, Qinghua Meng, Chuanhai Wang, Shi Chen, Xiaojiang Wang, Zhiyang Zhu, Cheng Jiang, Yi Shi, Shuang Liu, Chenghong Li
Pages: 89-96
Published online on: 28 April 2017

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Case Report Open Access

Acute myeloid leukemia with t(3;21)(q26.2;q22) developing following low‑dose methotrexate therapy for rheumatoid arthritis and expressing two AML1/MDS1/EVI1 fusion proteins: A case report

Keisuke Tanaka, Gaku Oshikawa, Hiroki Akiyama, Shinya Ishida, Toshikage Nagao, Masahide Yamamoto, Osamu Miura
Pages: 97-102
Published online on: 10 May 2017

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Article Open Access

Effect of 2‑methoxyestradiol on SK‑LMS‑1 uterine leiomyosarcoma cells

Ji‑Sun Lee, Changhwan Ahn, Hee Young Kang, Eui‑Bae Jeung
Pages: 103-110
Published online on: 12 May 2017

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Article Open Access

MicroRNA‑4530 promotes angiogenesis by targeting VASH1 in breast carcinoma cells

Tao Zhang, Li Jing, Hong Li, Linchao Ding, Dongdong Ai, Jianxin Lyu, Lianjin Zhong
Pages: 111-118
Published online on: 28 April 2017

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Article Open Access

Altered expression of cytokeratin 7 and CD117 in transitional mucosa adjacent to human colorectal cancer

Hideaki Kigasawa, Masachika Fujiwara, Jun Ishii, Tomohiro Chiba, Yuichi Terado, Hiroaki Shimoyamada, Makoto Mochizuki, Osamu Kitamura, Hiroshi Kamma, Yasuo Ohkura
Pages: 119-126
Published online on: 11 May 2017

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Case Report Open Access

Denosumab-related osteonecrosis of the jaw in a patient with bone metastases of prostate cancer: A case report and literature review

Hitoshi Yoshimura, Seigo Ohba, Hisato Yoshida, Kyoko Saito, Kazuyoshi Inui, Rie Yasui, Dai Ichikawa, Minako Aiki, Junichi Kobayashi, Shinpei Matsuda, Yoshiaki Imamura, Kazuo Sano
Pages: 127-136
Published online on: 04 May 2017

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Article Open Access

Association between chromosomal aberration of exfoliated bladder cells in the urine and oxidative stress in patients with bladder transitional cell carcinoma

Dong Wang, Jia‑Fu Feng, Guang‑Ya Yuan, Yong‑Hong Yang, Yun‑Shuang Liu, Yu‑Wei Yang
Pages: 137-144
Published online on: 05 May 2017

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Article Open Access

Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells

Yingchun Qu, Peifang Cong, Chengjiang Lin, Yihui Deng, Jesse Li‑Ling, Meixia Zhang
Pages: 145-152
Published online on: 10 May 2017

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Case Report Open Access

Pancreatic intraductal tubulopapillary neoplasm with associated invasive cancer successfully treated by total pancreatectomy: A case report

Yuji Fujimoto, Yoshito Tomimaru, Hiromi Tamura, Kozo Noguchi, Hirotsugu Nagase, Atsushi Hamabe, Masashi Hirota, Kazuteru Oshima, Tsukasa Tanida, Tomono Kawase, Shunji Morita, Hiroshi Imamura, Takashi Iwazawa, Kenzo Akagi, Masashi Yamamoto, Tsutomu Nishida, Shiro Adachi, Keizo Dono
Pages: 153-158
Published online on: 05 May 2017

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Article Open Access

Expression levels and clinical significance of hepsin and HMGB1 proteins in cervical carcinoma

Hui Cheng, Weiqi Wang, Yanling Zhang, Bei Zhang, Jie Cheng, Peng Teng, Xin Tang
Pages: 159-164
Published online on: 03 May 2017

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Article Open Access

Comparison of different methods for nutrition assessment in patients with tumors

Hongzhen Du, Bingbing Liu, Ying Xie, Jinli Liu, Yujia Wei, Huanyu Hu, Bin Luo, Zengning Li
Pages: 165-170
Published online on: 11 May 2017

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Article Open Access

DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells

Yu‑Hsien Lee, Hui‑Wen Yang, Li‑Chiu Yang, Ming‑Yi Lu, Lo‑Lin Tsai, Shun‑Fa Yang, Yu‑Feng Huang, Ming‑Yung Chou, Cheng‑Chia Yu, Fang‑Wei Hu
Pages: 171-179
Published online on: 08 May 2017

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Article Open Access

Application of small intestine decompression combined with oral feeding in middle and late period of malignant small bowel obstruction

Dechun Li, Hongtao Du, Guoqing Shao, Yongtuan Guo, Wan Lu, Ruihong Li
Pages: 180-184
Published online on: 11 May 2017

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Article Open Access

Multicenter research into the quality of life of patients with advanced oropharyngeal carcinoma with long‑term survival associated with human papilloma virus

Giacomo Spinato, Marco Stellin, Giuseppe Azzarello, Deborah Bonazza, Fabrizio Zanconati, Doriano Politi, Salvatore Cocuzza, Paola Di Mauro, Simonetta Ausoni, Giovanni Tonoli, Giulio Costantini, Luigi Maiolino, Roberto Spinato, Maria Cristina Da Mosto, Lorena Baboci, Annarosa Del Mistro, Agostino Serra, Giancarlo Tirelli
Pages: 185-193
Published online on: 10 May 2017

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Article Open Access

Clinical outcome of brain metastases differs significantly among breast cancer subtypes

Nadja E. Oehrlich, Loukia M. Spineli, Frank Papendorf, Tjoung‑Won Park‑Simon
Pages: 194-200
Published online on: 12 May 2017

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Article Open Access

Association between the expression of microRNAs and the response of patients with locally advanced rectal cancer to preoperative chemoradiotherapy

Anne Haahr Mellergaard Eriksen, Flemming Brandt Sørensen, Rikke Fredslund Andersen, Anders Jakobsen, Torben Frøstrup Hansen
Pages: 201-209
Published online on: 09 May 2017

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Article Open Access

Transrectal real-time tissue elastography targeted biopsy coupled with peak strain index improves the detection of clinically important prostate cancer

Qi Ma, Dong‑Rong Yang, Bo‑Xin Xue, Cheng Wang, Han‑Bin Chen, Yun Dong, Cai‑Shan Wang, Yu‑Xi Shan
Pages: 210-216
Published online on: 05 May 2017

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Article Open Access

Detection of OPCML methylation, a possible epigenetic marker, from free serum circulating DNA to improve the diagnosis of early-stage ovarian epithelial cancer

Bi Wang, Lei Yu, Xin Luo, Lin Huang, Qin‑Shan Li, Xiao‑Shan Shao, Yi Liu, Yu Fan, Guo‑Zhen Yang
Pages: 217-223
Published online on: 03 May 2017

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Article Open Access

Study on the association of the polymorphism of HLA-II gene with leukemia

Jiang Wu, Yu Song, Fei Chen, Hui Xiao
Pages: 224-228
Published online on: 08 May 2017

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Article Open Access

Relationship between MGMT gene expression and treatment effectiveness and prognosis in glioma

Qiang Li, Jiang Guo, Weisheng Wang, Dingkun Wang
Pages: 229-233
Published online on: 05 May 2017

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Article Open Access

Cantharidin alters the expression of genes associated with the NKG2D-associated immune response in TSGH-8301 human bladder carcinoma cells

Jehn‑Hwa Kuo, An‑Cheng Huang, Jen‑Jyh Lin, Kuang‑Chi Lai, Rick Sai‑Chuen Wu, Jiun‑Long Yang, Bin‑Chuan Ji, Mei‑Due Yang, Yung‑Lin Chu, Jing‑Gung Chung
Pages: 234-240
Published online on: 12 May 2017

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Article Open Access

Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via a cyclin‑dependent kinase‑independent mechanism Corrigendum in /10.3892/ol.2021.12529

Lingling Si, Xinhui Yang, Xinyan Yan, Yanming Wang, Qiusheng Zheng
Pages: 241-249
Published online on: 12 May 2017

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Article Open Access

PD‑L1 and PD‑1 expression correlate with prognosis in extrahepatic cholangiocarcinoma

Ke Ma, Xin Wei, Danfeng Dong, Yinying Wu, Qianqian Geng, Enxiao Li
Pages: 250-256
Published online on: 28 April 2017

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Case Report Open Access

Kikuchi-Fujimoto disease in the regional lymph nodes with node metastasis in a patient with tongue cancer: A case report and literature review

Tessho Maruyama, Kazuhide Nishihara, Masanao Saio, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Takahiro Goto, Naoki Yoshimi, Akira Arasaki
Pages: 257-263
Published online on: 09 May 2017

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Article Open Access

Monocyte chemoattractant protein 1 expression and proliferation in primary central nervous system lymphoma

Yoshinobu Takahashi, Takahiro Sawada, Toshiaki Akahane, Yumiko Kawase, Hidetoshi Ikeda, Keishi Makino, Hideo Nakamura, Takuichiro Hide, Shigetoshi Yano, Naoya Hashimoto, Hajime Kamada
Pages: 264-270
Published online on: 04 May 2017

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Article Open Access

Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children

Li Li, Chi Xu, Pingtao Liu, Jia Huang
Pages: 271-275
Published online on: 08 May 2017

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Article

The enhanced tumor inhibitory effects of gefitinib and L‑ascorbic acid combination therapy in non‑small cell lung cancer cells

Kyoung Eun Lee, Eunsil Hahm, Seyeon Bae, Jae Seung Kang, Wang Jae Lee
Pages: 276-282
Published online on: 02 May 2017

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Article

Quantitative analysis and clonal characterization of T-cell receptor β repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine

Tu Mai, Atsushi Takano, Hiroyuki Suzuki, Takashi Hirose, Takahiro Mori, Koji Teramoto, Kazuma Kiyotani, Yusuke Nakamura, Yataro Daigo
Pages: 283-292
Published online on: 05 May 2017

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Article

Glasgow prognostic score predicts therapeutic outcome after hepatic resection for hepatocellular carcinoma

Hiroaki Shiba, Takashi Horiuchi, Taro Sakamoto, Kenei Furukawa, Yoshihiro Shirai, Tomonori Iida, Yuki Fujiwara, Koichiro Haruki, Katsuhiko Yanaga
Pages: 293-298
Published online on: 28 April 2017

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Article

A comparison of clinicopathological features and prognosis in prostate cancer between atomic bomb survivors and control patients

Koichi Shoji, Jun Teishima, Tetsutaro Hayashi, Shunsuke Shinmei, Tomoyuki Akita, Kazuhiro Sentani, Yukio Takeshima, Koji Arihiro, Junko Tanaka, Wataru Yasui, Akio Matsubara
Pages: 299-305
Published online on: 04 May 2017

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Article

Evaluation of erlotinib for the treatment of patients with non-small cell lung cancer with epidermal growth factor receptor wild type

Fumihiko Hirai, Makoto Edagawa, Shinichiro Shimamatsu, Ryo Toyozawa, Gouji Toyokawa, Kaname Nosaki, Masafumi Yamaguchi, Takashi Seto, Mitsuhiro Takenoyama, Yukito Ichinose
Pages: 306-312
Published online on: 04 May 2017

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Article

Prognostic significance of ABCB1 in stage I lung adenocarcinoma

Fenfei Zou, Masahiro Seike, Rintaro Noro, Shinobu Kunugi, Kaoru Kubota, Akihiko Gemma
Pages: 313-321
Published online on: 10 May 2017

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Article

Temozolomide induces autophagy in primary and established glioblastoma cells in an EGFR independent manner

Silvia Würstle, Fabian Schneider, Florian Ringel, Jens Gempt, Friederike Lämmer, Claire Delbridge, Wei Wu, Jürgen Schlegel
Pages: 322-328
Published online on: 02 May 2017

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Article

Silencing platelet‑derived growth factor receptor‑β enhances the radiosensitivity of C6 glioma cells in vitro and in vivo

Ji‑Dong Hong, Xia Wang, Yu‑Ping Peng, Jiang‑Hua Peng, Jun Wang, Ye‑Ping Dong, Dan He, Zhen‑Zi Peng, Qing‑Song Tu, Liang‑Fang Sheng, Mei‑Zuo Zhong, Chao‑Jun Duan
Pages: 329-336
Published online on: 10 May 2017

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Article

Predictive and prognostic significance of CD8+ tumor‑infiltrating lymphocytes in patients with luminal B/HER 2 negative breast cancer treated with neoadjuvant chemotherapy

Khalid Al‑Saleh, Nashwa Abd El‑Aziz, Arwa Ali, Waleed Abozeed, Ahmed Abd El‑Warith, Ahmed Ibraheem, Jawaher Ansari, Ammar Al‑Rikabi, Sufia Husain, Jean‑Marc Nabholtz
Pages: 337-344
Published online on: 10 May 2017

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Article

BRCA1 expression serves a role in vincristine resistance in colon cancer cells

Zhongjie Xu, Lirong Zhang
Pages: 345-348
Published online on: 10 May 2017

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Article

Functional analysis of CD14+HLA-DR-/low myeloid-derived suppressor cells in patients with lung squamous cell carcinoma

Yun Chen, Guichang Pan, Dongbo Tian, Yifei Zhang, Taoping Li
Pages: 349-354
Published online on: 10 May 2017

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Article

Flexible magnifying endoscopy with narrow band imaging for the diagnosis of uterine cervical tumors: A cooperative study among gastrointestinal endoscopists and gynecologists to explore a novel microvascular classification system

Noriko Nishiyama, Kenji Kanenishi, Hirohito Mori, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Nobuya Kobayashi, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Ayako Fujimori, Makoto Oryu, Chiaki Tenkumo, Megumi Ishibashi, Uiko Hanaoka, Toshiyuki Hata, Yumi Miyai, Kyuichi Kadota, Reiji Haba, Tsutomu Masaki
Pages: 355-362
Published online on: 11 May 2017

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Article

Low expression of microRNA‑30c promotes prostate cancer cells invasion involved in downregulation of KRAS protein

Jun Zhang, Xilong Wang, Yangyun Wang, Ruixian Peng, Zhiyuan Lin, Yang Wang, Bo Hu, Jifeng Wang, Guowei Shi
Pages: 363-368
Published online on: 12 May 2017

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Article

Presurgical neoadjuvant targeted molecular therapy for kidney cancer with concomitant vena cava tumor embolus: A clinical study

Gang Guo, Wei Cai, Hongzhao Li, Jiangping Gao, Xin Ma, Jun Dong, Weijun Fu, Xu Zhang
Pages: 369-375
Published online on: 05 May 2017

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Article

Association between periostin and epithelial-mesenchymal transition in esophageal squamous cell carcinoma and its clinical significance

Ya‑Jing Lv, Wei Wang, Chu‑Shu Ji, Wei Jia, Ming‑Ran Xie, Bing Hu
Pages: 376-382
Published online on: 05 May 2017

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Article

Soluble urokinase‑type plasminogen activator receptor and urokinase‑type plasminogen activator receptor contribute to chemoresistance in leukemia

Hong Guo, Lan‑Xia Zhou, Haizhen Ma, Bei Liu, Juan Cheng, Yun‑Yun Ma, Li Zhao
Pages: 383-389
Published online on: 10 May 2017

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Article

Distinct DNA methylation alterations are associated with cribriform architecture and intraductal carcinoma in Gleason pattern 4 prostate tumors

Ekaterina Olkhov‑Mitsel, Farshid Siadat, Ken Kron, Liyang Liu, Andrea J. Savio, John Trachtenberg, Neil Fleshner, Theodorus van der Kwast, Bharati Bapat
Pages: 390-396
Published online on: 09 May 2017

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Article

Location of the meso-pancreatoduodenum as a regional lymphatic basin for pancreatic head carcinoma

Hirofumi Terakawa, Hirohisa Kitagawa, Isamu Makino, Hironori Hayashi, Katsunobu Oyama, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Noriyuki Ozaki, Tetsuo Ohta
Pages: 397-403
Published online on: 09 May 2017

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High expression of P21‑activated kinase 5 protein is associated with poor survival in gastric cancer

Tomoki Aburatani, Mikito Inokuchi, Yoko Takagi, Toshiaki Ishikawa, Keisuke Okuno, Kentaro Gokita, Chiharu Tomii, Toshiro Tanioka, Hideaki Murase, Sho Otsuki, Hiroyuki Uetake, Kazuyuki Kojima, Tatsuyuki Kawano
Pages: 404-410
Published online on: 03 May 2017

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Article

Expression of autophagy‑associated proteins in papillary thyroid carcinoma

Meiliu Yang, Lu Bai, Wu Yu, Xueling Sun, Gang Xu, Ruhua Guan, Ying Yang, Mingyue Qiu, Yazhong Zhang, Jinli Tian, Hui Fang
Pages: 411-415
Published online on: 28 April 2017

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Article

Withaferin A inhibits the proliferation of gastric cancer cells by inducing G2/M cell cycle arrest and apoptosis

Green Kim, Tae‑Hyoun Kim, Eun‑Ha Hwang, Kyu‑Tae Chang, Jung Joo Hong, Jong‑Hwan Park
Pages: 416-422
Published online on: 12 May 2017

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Article

Cholangiocarcinoma following external beam radiotherapy: A report of two cases

Anisha Kulkarni, Justin S. Gundara, Anthony J. Gill, Thomas J. Hugh, Jaswinder S. Samra
Pages: 423-426
Published online on: 03 May 2017

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Article

Salinomycin inhibits canine mammary carcinoma in vitro by targeting cancer stem cells

Hongchao Du, Bin Zhou, Hong Zhang, Yipeng Jin, Di Zhang, Degui Lin
Pages: 427-432
Published online on: 12 May 2017

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Article

Consecutive stimulation of HBsAg promotes the viability of the human B lymphoblastoid cell line IM‑9 through regulating the SIRT1‑NF‑κB pathway Retraction in /10.3892/ol.2023.13825

Jian Bo, Xiaojuan Wang, Jie Li, Wenqing Wang, Jinqian Zhang
Pages: 433-440
Published online on: 03 May 2017

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Article

Epigallocatechin gallate inhibits the growth of MDA‑MB‑231 breast cancer cells via inactivation of the β‑catenin signaling pathway

On‑Yu Hong, Eun‑Mi Noh, Hye‑Yeon Jang, Young‑Rae Lee, Byoung Kil Lee, Sung Hoo Jung, Jong‑Suk Kim, Hyun Jo Youn
Pages: 441-446
Published online on: 02 May 2017

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Article

Solamargine inhibits the migration and invasion of HepG2 cells by blocking epithelial-to-mesenchymal transition

Xiaodong Xie, Haitao Zhu, Jia Zhang, Meiqin Wang, Li Zhu, Zhen Guo, Wenrong Shen, Dongqing Wang
Pages: 447-452
Published online on: 10 May 2017

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Effect of primary tumor location and tumor size on the response to radiotherapy for liver metastases from colorectal cancer

Hiroshi Doi, Kenji Uemoto, Osamu Suzuki, Koichi Yamada, Norihisa Masai, Daisaku Tatsumi, Hiroya Shiomi, Ryoong‑Jin Oh
Pages: 453-460
Published online on: 12 May 2017

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Article

Regorafenib diminishes the expression and secretion of angiogenesis and metastasis associated proteins and inhibits cell invasion via NF-κB inactivation in SK-Hep1 cells

Yu‑Chang Liu, Reng‑Hong Wu, Wei‑Shu Wang
Pages: 461-467
Published online on: 09 May 2017

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Article

Allicin inhibits the invasion of lung adenocarcinoma cells by altering tissue inhibitor of metalloproteinase/matrix metalloproteinase balance via reducing the activity of phosphoinositide 3-kinase/AKT signaling

Ling Huang, Yuanhong Song, Jianping Lian, Zhiwei Wang
Pages: 468-474
Published online on: 05 May 2017

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Article

Combination of lenalidomide and low-dose dexamethasone therapy promotes the anticoagulant activity of warfarin in patients with immunoglobulin light-chain amyloidosis

Fumiaki Kitazawa, Shin‑Ichi Fuchida, Fumitaka Ise, Yoko Kado, Kumi Ueda, Takatoshi Kokufu, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Yuko Nakayama, Kohji Takara, Chihiro Shimazaki
Pages: 475-479
Published online on: 08 May 2017

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Article

MicroRNA‑125b targeted STAT3 to inhibit laryngeal squamous cell carcinoma cell growth and motility

Juan Feng, Yuqin Fan, Qukuerhan Ayiheng, Hua Zhang, Jun Yong, Bin Hu
Pages: 480-486
Published online on: 11 May 2017

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Review

Early diagnosis of venous thromboembolism as a clinical primary symptom of occult cancer: Core proteins of a venous thrombus (Review)

Siwan Wen, Qianglin Duan, Fan Yang, Guiyuan Li, Lemin Wang
Pages: 491-496
Published online on: 16 May 2017

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Review Open Access

Recent developments in predictive biomarkers of pediatric glioma (Review)

Zhengwei Li, Yiyu Yin, Fengli Liu
Pages: 497-500
Published online on: 24 May 2017

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Pulmonary toxicity generated from radiotherapeutic treatment of thoracic malignancies (Review)

Guodong Deng, Ning Liang, Jian Xie, Hui Luo, Lili Qiao, Jingxin Zhang, Dawei Wang, Jiandong Zhang
Pages: 501-511
Published online on: 26 May 2017

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Epidermal growth factor receptor in glioblastoma (Review)

Hongsheng Xu, Hailiang Zong, Chong Ma, Xing Ming, Ming Shang, Kai Li, Xiaoguang He, Hai Du, Lei Cao
Pages: 512-516
Published online on: 22 May 2017

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Sorafenib induced alteration of protein glycosylation in hepatocellular carcinoma cells

Tianhua Liu, Riqiang Liu, Shu Zhang, Kun Guo, Qinle Zhang, Wei Li, Yinkun Liu
Pages: 517-524
Published online on: 16 May 2017

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S100P is associated with proliferation and migration in nasopharyngeal carcinoma

Yueyang Liu, Chengyu Wang, Xiaodong Shan, Jian Wu, Huanhai Liu, Haibin Liu, Jiping Zhang, Weihua Xu, Zhirong Sha, Jin He, Jingping Fan
Pages: 525-532
Published online on: 17 May 2017

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pPeOp from Omphalia lapidescens Schroet induces cell cycle arrest and inhibits the migration of MC‑4 gastric tumor cells

Yong‑Le Yang, Wei‑Yao Gong, Fei‑Fei Chen, Lu‑Chao Chen, Yi‑Tao Chen
Pages: 533-540
Published online on: 19 May 2017

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Involvement of the TGFβ1/Smad2/MMP3 signaling pathway in SB431542-induced inhibition of cell invasion in multiple myeloma RPMI 8226 cells

Huang Xi, Qi‑Guo Shuai, Lin‑Li Shao
Pages: 541-546
Published online on: 26 May 2017

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Case Report Open Access

Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography: A case report

Anneleen De Both, Marc De Man, Roberto Troisi, Hans Van Vlierberghe, Anne Hoorens, Karen Geboes
Pages: 547-552
Published online on: 24 May 2017

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Oncogenic function of angiopoietin-2 in vitro and its modulation of tumor progression in colorectal carcinoma

Hyungjoo Kim, Tae Sung Ahn, Chang‑Jin Kim, Sang Byung Bae, Han Jo Kim, Chang‑Seuk Lee, Tae Hyun Kim, Jungkyun Im, Sang Hun Lee, Myoung Won Son, Moon Soo Lee, Moo Jun Baek, Dongjun Jeong
Pages: 553-560
Published online on: 18 May 2017

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Role of T helper 17 cytokines in the tumour immune inflammation response of patients with laryngeal squamous cell carcinoma

Wei‑Jing Tang, Lei Tao, Li‑Ming Lu, Di Tang, Xiao‑Lin Shi
Pages: 561-568
Published online on: 25 May 2017

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99mTc-LHRH in tumor receptor imaging

Dawei Hao, Lingfei Sun, Xiang Hu, Xiaowen Hao
Pages: 569-578
Published online on: 24 May 2017

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Efficacy and safety of SOX chemotherapy with or without surgery in AFP-producing advanced gastric cancer

Zhu Li, Xu Hou, Juan Chen, Huidong Sun, Yuetang Mi, Yongling Sui, Yuhong Li, Jiaping Xie, Yingli Qiao, Xiaofeng Lei, Xiaoshuang Che, Jun Liu
Pages: 579-586
Published online on: 24 May 2017

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Article Open Access

Frequent aberrant p53 and Fhit expression in endoscopically resected superficial hypopharyngeal cancer and esophageal cancer

Sohei Yamamoto, Kazuo Yashima, Soichiro Kawata, Kohei Hosoda, Akihiro Tamoto, Yuichiro Ikebuchi, Kazuya Matsumoto, Koichiro Kawaguchi, Kenichi Harada, Yoshikazu Murawaki, Hajime Isomoto
Pages: 587-592
Published online on: 29 May 2017

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Case Report Open Access

Resistance to epithelial growth factor receptor tyrosine kinase inhibitors in a patient with transformation from lung adenocarcinoma to small cell lung cancer: A case report

Liying Fang, Jian He, Jingwen Xia, Liang Dong, Xiujuan Zhang, Yaqin Chai, Ying Li, Mengjie Niu, Tianxing Hang, Shengqing Li
Pages: 593-598
Published online on: 23 May 2017

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Article Open Access

Predictive role of human equilibrative nucleoside transporter 1 in patients with pancreatic cancer treated by curative resection and gemcitabine-only adjuvant chemotherapy

Toru Aoyama, Keisuke Kazama, Yohei Miyagi, Masaaki Murakawa, Koichiro Yamaoku, Yosuke Atsumi, Manabu Shiozawa, Makoto Ueno, Manabu Morimoto, Takashi Oshima, Norio Yukawa, Takaki Yoshikawa, Yasushi Rino, Munetaka Masuda, Soichiro Morinaga
Pages: 599-606
Published online on: 19 May 2017

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Article Open Access

Korean Scutellaria baicalensis Georgi flavonoid extract induces mitochondrially mediated apoptosis in human gastric cancer AGS cells

Venu Venkatarame Gowda Saralamma, Ho Jeong Lee, Gyeong Eun Hong, Hyeon Soo Park, Silvia Yumnam, Suchismita Raha, Won Sup Lee, Eun Hee Kim, Nak Ju Sung, Sang Joon Lee, Jeong Doo Heo, Gon Sup Kim
Pages: 607-614
Published online on: 17 May 2017

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Recruitment of CD11b+Ly6C+ monocytes in non‑small cell lung cancer xenografts challenged by anti-VEGF antibody

Xie‑Wan Chen, Jian‑Guo Sun, Lu‑Ping Zhang, Xing‑Yun Liao, Rong‑Xia Liao
Pages: 615-622
Published online on: 24 May 2017

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Clustering of patients with intrahepatic cholangiocarcinoma based on serum periostin may be predictive of prognosis

Chanitra Thuwajit, Peti Thuwajit, Pranisa Jamjantra, Chawalit Pairojkul, Sopit Wongkham, Vajarabhongsa Bhudhisawasdi, Junya Ono, Shoichiro Ohta, Kiminori Fujimoto, Kenji Izuhara
Pages: 623-634
Published online on: 25 May 2017

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Expression of FOXC2, PinX1, Ki-67 and Cyclin D1 in cutaneous cell carcinoma

Haiying Zhao, Yunfeng Cao, Guoqiang Wang, Zengxiang Luo
Pages: 635-638
Published online on: 24 May 2017

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Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer Corrigendum in /10.3892/ol.2021.12772

Norihiko Suzuki, Fumio Nakagawa, Teiji Takechi
Pages: 639-646
Published online on: 26 May 2017

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Transforming growth factor‑β1 contributes to oxaliplatin resistance in colorectal cancer via epithelial to mesenchymal transition

Liang Mao, Yan Li, Jinping Zhao, Qia Li, Bin Yang, Yuanyuan Wang, Zhitu Zhu, Hongzhi Sun, Zhenhua Zhai
Pages: 647-654
Published online on: 19 May 2017

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Meta-analysis of the role of bevacizumab in extensive stage small cell lung cancer

Yan‑Juan Zhu, Hai‑Bo Zhang, Yi‑Hong Liu, Jian‑Ping Bai, Yong Li, Li‑Rong Liu, Yan‑Chun Qu, Xin Qu, Xian Chen
Pages: 655-664
Published online on: 25 May 2017

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F-18 fluorodeoxyglucose positron emission tomography for differential diagnosis and prognosis prediction of vascular tumors

Won Woo Lee, Young So, Seo Young Kang, Min‑Kyung So, Haeryoung Kim, Hyun Woo Chung, Wan Seop Kim, Sang Eun Kim
Pages: 665-672
Published online on: 17 May 2017

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Remodeling of energy metabolism by a ketone body and medium-chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara‑Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Pages: 673-680
Published online on: 17 May 2017

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Fatty acids inhibit anticancer effects of 5-fluorouracil in mouse cancer cell lines

Eriko Tanabe, Misaho Kitayoshi, Kiyomu Fujii, Hitoshi Ohmori, Yi Luo, Yui Kadochi, Shiori Mori, Rina Fujiwara, Yukiko Nishiguchi, Takamitsu Sasaki, Hiroki Kuniyasu
Pages: 681-686
Published online on: 17 May 2017

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Identification of differentially expressed inflammatory factors in Wilms' tumors and their association with patient outcomes

Fei Guo, Junjie Zhang, Lei Wang, Wei Zhao, Jiekai Yu, Shu Zheng, Jiaxiang Wang
Pages: 687-694
Published online on: 26 May 2017

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Distinct subcellular localization of E-cadherin between epithelioid angiomyolipoma and triphasic angiomyolipoma: A preliminary case-control study

Xin‑Gang Bi, Lei Guo, Xiao‑Liang Wang, Qian Wei, Qiang Du, Wen‑Hao Jiang, Guang‑Yuan Zheng, Hong‑Tu Zhang, Jian‑Hui Ma, Shan Zheng
Pages: 695-704
Published online on: 29 May 2017

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Validation and ranking of seven staging systems of hepatocellular carcinoma

Zhan‑Hong Chen, Ying‑Fen Hong, Jinxiang Lin, Xing Li, Dong‑Hao Wu, Jing‑Yun Wen, Jie Chen, Dan‑Yun Ruan, Qu Lin, Min Dong, Li Wei, Tian‑Tian Wang, Ze‑Xiao Lin, Xiao‑Kun Ma, Xiang‑Yuan Wu, Ruihua Xu
Pages: 705-714
Published online on: 22 May 2017

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Dynamic MRI follow-up of radiation encephalopathy in the temporal lobe following nasopharyngeal carcinoma radiotherapy

Xiaofeng Zhou, Xiaofang Liao, Xiaoqiu Ren, Kewei Xiang, Qiongge Hu, Minming Zhang, Huijuan He, Li Shen, Qichun Wei
Pages: 715-724
Published online on: 17 May 2017

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Screening of potentially crucial genes and regulatory factors involved in epithelial ovarian cancer using microarray analysis

Can Shi, Zhenyu Zhang
Pages: 725-732
Published online on: 17 May 2017

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Polymorphisms of ‑800G/A and +915G/C in TGF‑β1 gene and lung cancer susceptibility

Qing‑Guo Di, Bao‑Hua Sun, Ming‑Ming Jiang, Jun‑Feng Du, Zhi‑Tao Mai, Xin  Zhang, Li‑Rong Zhou, Yu‑Min Chi, Jing Lv
Pages: 733-736
Published online on: 16 May 2017

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Expression of methylation-modulated tumor-related genes in endoscopically resected early esophageal squamous neoplasia

Kohei Hosoda, Kazuo Yashima, Akihiro Tamoto, Sohei Yamamoto, Soichiro Kawata, Yuichiro Ikebuchi, Kazuya Matsumoto, Koichiro Kawaguchi, Kenichi Harada, Yoshikazu Murawaki, Hajime Isomoto
Pages: 737-742
Published online on: 17 May 2017

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MicroRNAs as outcome predictors in patients with metastatic colorectal cancer treated with bevacizumab in combination with FOLFOX

I. Kiss, J. Mlčochová, K. Součková, P. Fabian, A. Poprach, J. Halamkova, M. Svoboda, R. Vyzula, O. Slaby
Pages: 743-750
Published online on: 26 May 2017

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Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study

Ruinian Zheng, Kexu Chen, Yu Zhang, Jie Huang, Fengrong Shi, Gang Wu, Senming Wang
Pages: 751-757
Published online on: 16 May 2017

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Impact of RASSF1A gene methylation on the metastatic axillary nodal status in breast cancer patients

Eva Jezkova, Pavol Zubor, Karol Kajo, Marian Grendar, Karol Dokus, Marian Adamkov, Zora Lasabova, Lukas Plank, Jan Danko
Pages: 758-766
Published online on: 18 May 2017

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MicroRNA-195 inhibits the behavior of cervical cancer tumors by directly targeting HDGF Retraction in /10.3892/ol.2024.14597

Rongrong Song, Lin Cong, Guantai Ni, Min Chen, Honmei Sun, Yunxia Sun, Meiling Chen
Pages: 767-775
Published online on: 19 May 2017

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Pre-operative evaluation of circulating KL-6 levels as a biomarker for epithelial ovarian carcinoma and its correlation with tumor MUC1 expression Corrigendum in /10.3892/ol.2017.6794

Sho Sato, Tomomi Kato, Kenji Abe, Tatsuya Hanaoka, Yuri Yano, Akira Kurosaki, Masanori Yasuda, Tetsuo Sekino, Keiichi Fujiwara, Kosei Hasegawa
Pages: 776-786
Published online on: 25 May 2017

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Relapsed anaplastic lymphoma kinase-positive large B-cell lymphoma expressed cluster of differentiation 4 and cytokeratin: An initially misdiagnosed case corrected by immunoglobulin κ locus gene rearrangement detection

Yunfei Shi, Xianghong Li, Yuqin Song, Lixin Zhou, Qin Feng, Ping Wang, Chen Zhang, Weiping Liu, Yanhua Bai, Yumei Lai
Pages: 787-791
Published online on: 17 May 2017

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Japanese apricot extract (MK615) potentiates bendamustine-induced apoptosis via impairment of the DNA damage response in lymphoma cells

Masaya Inoue, Yoshio Honma, Takeshi Urano, Junji Suzumiya
Pages: 792-800
Published online on: 19 May 2017

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Significance of CD47 expression in gastric cancer

Tomoya Sudo, Yusuke Takahashi, Genta Sawada, Ryutaro Uchi, Koshi Mimori, Yoshito Akagi
Pages: 801-809
Published online on: 26 May 2017

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Inhibitory effects of delphinidin on the proliferation of ovarian cancer cells via PI3K/AKT and ERK 1/2 MAPK signal transduction

Whasun Lim, Gwonhwa Song
Pages: 810-818
Published online on: 23 May 2017

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Intranuclear accumulation of galectin-3 is an independent prognostic factor for patients with distal cholangiocarcinoma

Tatsuo Shimura, Yasuhide Kofunato, Ryo Okada, Rei Yashima, Yoshihisa Koyama, Kenichiro Araki, Hiroyuki Kuwano, Seiichi Takenoshita
Pages: 819-829
Published online on: 25 May 2017

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Biological effects and clinical characteristics of microRNA‑106a in human colorectal cancer

Yuzheng He, Guiqi Wang, Lei Zhang, Congjie Zhai, Jun Zhang, Xusheng Zhao, Xia Jiang, Zengren Zhao
Pages: 830-836
Published online on: 16 May 2017

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Melanoma antigen-encoding gene family member A1-6 and hTERT in the detection of circulating tumor cells following CD45‑ depletion and RNA extraction

Dae‑Dong Kim, Chun‑Seok Yang, Hyun‑Dong Chae, Sang‑Gyu Kwak, Chang‑Ho Jeon
Pages: 837-843
Published online on: 22 May 2017

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The novel immunomodulator IMMUNEPOTENT CRP combined with chemotherapy agent increased the rate of immunogenic cell death and prevented melanoma growth

Maria del Carmen Rodríguez‑Salazar, Moises Armides Franco‑Molina, Edgar Mendoza‑Gamboa, Ana Carolina Martínez‑Torres, Pablo Zapata‑Benavides, Jose Sullivan López‑González, Erika Evangelina Coronado‑Cerda, Juan Manuel Alcocer‑González, Reyes Silvestre Tamez‑Guerra, Cristina Rodríguez‑Padilla
Pages: 844-852
Published online on: 18 May 2017

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Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis

Kyung‑Hwa Kang, Min Ho Han, Jin‑Woo Jeong, Cheol Park, Sang‑Hyup Lee, Hai Woong Lee, Sang Hoon Hong, Yung Hyun Choi, Su Hyun Hong
Pages: 853-859
Published online on: 22 May 2017

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RT-qPCR for PHOX2B mRNA is a highly specific and sensitive method to assess neuroblastoma minimal residual disease in testicular tissue

Victoria Grèze, Justyna Kanold, Fanny Chambon, Pascale Halle, Anne‑Sophie Gremeau, Nathalie Rives, Nadège Rouel, Bruno Pereira, Andrei Tchirkov, Florence Brugnon
Pages: 860-866
Published online on: 24 May 2017

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Improvement of diagnostic efficiency in distinguishing the benign and malignant thyroid nodules via conventional ultrasound combined with ultrasound contrast and elastography

Mei-Juan Liu, Yan-Ming Men, Yong-Lin Zhang, Yu-Xi Zhang, Hao Liu
Pages: 867-871
Published online on: 24 May 2017

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Effects of remifentanil on hemodynamics, liver function and ICAM-1 expression in liver cancer patients undergoing surgery

Qi Jiang, Xiuling Song, Zheng Chen, Conghui Wang, Huiyu Luo
Pages: 872-876
Published online on: 24 May 2017

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Article

Genetic alterations in Japanese extrahepatic biliary tract cancer

Rei Noguchi, Kiyoshi Yamaguchi, Tsuneo Ikenoue, Yumi Terakado, Yasunori Ohta, Naohide Yamashita, Osamu Kainuma, Sana Yokoi, Yoshiaki Maru, Hiroki Nagase, Yoichi Furukawa
Pages: 877-884
Published online on: 22 May 2017

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Article

Evaluation of concurrent chemoradiotherapy for locally advanced NSCLC according to EGFR mutation status

Mikiko Ishihara, Satoshi Igawa, Jiichiro Sasaki, Sakiko Otani, Tomoya Fukui, Shinichiro Ryuge, Ken Katono, Yasuhiro Hiyoshi, Masashi Kasajima, Hisashi Mitsufuji, Masaru Kubota, Masanori Yokoba, Masato Katagiri, Akane Sekiguchi, Itaru Soda, Hiromichi Ishiyama, Kazushige Hayakawa, Noriyuki Masuda
Pages: 885-890
Published online on: 23 May 2017

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Article

Exon 7 splicing variant of estrogen receptor α is associated with pathological invasiveness in smoking‑independent lung adenocarcinoma

Ayumi Suzuki, Katsuhiro Okuda, Motoki Yano, Risa Oda, Tadashi Sakane, Osamu Kawano, Hiroshi Haneda, Satoru Moriyama, Makoto Nakanishi, Ryoichi Nakanishi
Pages: 891-898
Published online on: 19 May 2017

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Article

Hepatocyte selection medium-enriched hepatocellular carcinoma cells are positive for α-fetoprotein and CD44

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 899-902
Published online on: 24 May 2017

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Article

Bcl‑2/Bcl‑xL inhibitor ABT‑737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel‑induced cell death

Shuya Kasai, Takuya Sasaki, Ayano Watanabe, Masao Nishiya, Shinji Yasuhira, Masahiko Shibazaki, Chihaya Maesawa
Pages: 903-908
Published online on: 19 May 2017

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Article

Clinical features and surgical management of intracranial meningiomas in the elderly

Junkoh Yamamoto, Mayu Takahashi, Masaru Idei, Yoshiteru Nakano, Yoshiteru Soejima, Daisuke Akiba, Takehiro Kitagawa, Kunihiro Ueta, Ryo Miyaoka, Shigeru Nishizawa
Pages: 909-917
Published online on: 16 May 2017

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Article

Clinical outcomes of percutaneous radiofrequency ablation for small renal cancer

Keiichi Ito, Shigeyoshi Soga, Kenji Seguchi, Yusuke Shinchi, Ayako Masunaga, Shinsuke Tasaki, Kenji Kuroda, Akinori Sato, Junichi Asakuma, Akio Horiguchi, Hiroshi Shinmoto, Tatsumi Kaji, Tomohiko Asano
Pages: 918-924
Published online on: 26 May 2017

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Article

Telomere length is correlated with mitochondrial DNA copy number in intestinal, but not diffuse, gastric cancer

Soo‑Jung Jung, Ji‑Hyoung Cho, Won‑Jin Park, Yu‑Ran Heo, Jae‑Ho Lee
Pages: 925-929
Published online on: 17 May 2017

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Article

Elevated levels of mRNAs encoding dihydropyrimidine dehydrogenase and thymidylate synthase are associated with improved survival of patients with hepatocellular carcinoma treated with S-1

Yusuke Okano, Hidekazu Kuramochi, Go Nakajima, Satoshi Katagiri, Masakazu Yamamoto
Pages: 930-936
Published online on: 24 May 2017

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Article

Sodium butyrate enhances the growth inhibitory effect of sunitinib in human renal cell carcinoma cells

Hiromi Sato, Miaki Uzu, Tatsuro Kashiba, Rina Suzuki, Takuya Fujiwara, Hiroko Okuzawa, Koichi Ueno
Pages: 937-943
Published online on: 19 May 2017

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Article

Pirfenidone may revert the epithelial-to-mesenchymal transition in human lung adenocarcinoma

Ryota Kurimoto, Takahiro Ebata, Shunichiro Iwasawa, Tsukasa Ishiwata, Yuji Tada, Koichiro Tatsumi, Yuichi Takiguchi
Pages: 944-950
Published online on: 17 May 2017

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Article

UCP2 expression may represent a predictive marker of neoadjuvant chemotherapy effectiveness for locally advanced uterine cervical cancer

Kenji Imai, Takeshi Fukuda, Takuma Wada, Masaru Kawanishi, Reiko Tasaka, Tomoyo Yasui, Toshiyuki Sumi
Pages: 951-957
Published online on: 19 May 2017

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Article

MLH1 expression predicts the response to preoperative therapy and is associated with PD‑L1 expression in esophageal cancer

Kota Momose, Makoto Yamasaki, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
Pages: 958-964
Published online on: 19 May 2017

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Article

RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways

Yingdong Xu, Na Deng, Xiaoou Wang, Yinghui Chen, Guiji Li, Hua Fan
Pages: 965-970
Published online on: 17 May 2017

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Article

MicroRNA expression profiling in patients with hepatocellular carcinoma of familial aggregation and hepatitis B virus infection

Er‑Lei Zhang, Jin Gu, Zun‑Yi Zhang, Ke‑Shuai Dong, Bin‑Yong Liang, Zhi‑Yong Huang
Pages: 971-976
Published online on: 16 May 2017

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Case Report

Leiomyosarcoma of the splenic vein: A case report

Wenfang Wu, Xinxiang Zhao, Yan Wang, Cong Di, Renhui Cai, Yingxue Zhang, Siying Chen, Wei Zhang, Xin Yue
Pages: 977-980
Published online on: 22 May 2017

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Article

AXIN1 protects against testicular germ cell tumors via the PI3K/AKT/mTOR signaling pathway

Hailiang Xu, Yunyun Feng, Zhankui Jia, Jinjian Yang, Xueren Lu, Jun Li, Mingliang Xia, Chunru Wu, Yonggang Zhang, Jianhua Chen
Pages: 981-986
Published online on: 19 May 2017

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Article

Role of microRNA-296-3p in the malignant transformation of sinonasal inverted papilloma

Tomohiko Kakizaki, Hiromitsu Hatakeyama, Yuji Nakamaru, Dai Takagi, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma, Satoshi Fukuda
Pages: 987-992
Published online on: 17 May 2017

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Dermatofibrosarcoma protuberans of the breast: A case report

Kamil Pohlodek, Iveta Mečiarová, Petr Grossmann, Zdeněk Kinkor
Pages: 993-998
Published online on: 19 May 2017

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Article

Overexpression of the transmembrane protein BST-2 induces Akt and Erk phosphorylation in bladder cancer

Yoshinori Shigematsu, Naohide Oue, Yuri Nishioka, Naoya Sakamoto, Kazuhiro Sentani, Yohei Sekino, Shoichiro Mukai, Jun Teishima, Akio Matsubara, Wataru Yasui
Pages: 999-1004
Published online on: 23 May 2017

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Article

Knockdown of GluA2 induces apoptosis in non-small-cell lung cancer A549 cells through the p53 signaling pathway

Hong‑Yan Zhang, Wei Yang, Ji‑Bin Lu
Pages: 1005-1010
Published online on: 24 May 2017

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Article

Expression of survivin, MUC2 and MUC5 in colorectal cancer and their association with clinicopathological characteristics

Haipeng Wang, Shengjian Jin, Huiling Lu, Sisi Mi, Wenhua Shao, Xiaoxv Zuo, Huangyi Yin, Sien Zeng, Fumio Shimamoto, Guangying Qi
Pages: 1011-1016
Published online on: 19 May 2017

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Article

Clinical diagnosis and detection of genetic mutations of pancreatic metastases: A report of four cases and review of the literature

Ye Li, Zixiang Zhang, Yi Zhang, Jian Yang, Dongming Zhu, Dechun Li, Jian Zhou
Pages: 1017-1024
Published online on: 26 May 2017

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Article

Significance of E-cadherin and CD44 expression in patients with unresectable metastatic colorectal cancer

Yasuhito Iseki, Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Tetsuro Ikeya, Kosei Hirakawa
Pages: 1025-1034
Published online on: 26 May 2017

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Article

Hyperthermia and radiation reduce the toxic side-effects of bufadienolides for cancer therapy

Heba Emam, Alaa Refaat, Paras Jawaid, Mati Ur Rehman, Peng Li, Qing‑Li Zhao, Takashi Kondo
Pages: 1035-1040
Published online on: 26 May 2017

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Article

Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of a hTERT promoter at the 3'-side of the transgene

Endy Widya Putranto, Rie Kinoshita, Masami Watanabe, Takuya Sadahira, Hitoshi Murata, Ken‑Ichi Yamamoto, Junichiro Futami, Ken Kataoka, Yusuke Inoue, I. Made Winarsa Ruma, I. Wayan Sumardika, Chen Youyi, Miyoko Kubo, Yoshihiko Sakaguchi, Kenji Saito, Yasutomo Nasu, Hiromi Kumon, Nam‑Ho Huh, Masakiyo Sakaguchi
Pages: 1041-1048
Published online on: 17 May 2017

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Article

Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy in vitro

Tomohiro Osaki, Inoru Yokoe, Kiwamu Takahashi, Katsushi Inoue, Masahiro Ishizuka, Tohru Tanaka, Kazuo Azuma, Yusuke Murahata, Takeshi Tsuka, Norihiko Itoh, Tomohiro Imagawa, Yoshiharu Okamoto
Pages: 1049-1053
Published online on: 24 May 2017

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Article

Overexpression of mir-183 and mir-494 promotes proliferation and migration in human breast cancer cell lines

Taciane Macedo, Renato J. Silva‑Oliveira, Viviane A.O. Silva, Daniel O. Vidal, Adriane F. Evangelista, Marcia M.C. Marques
Pages: 1054-1060
Published online on: 26 May 2017

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Article Open Access

Decreased expression of miR-193a-3p is associated with poor prognosis in colorectal cancer

Maosong Lin, Bensong Duan, Jiangfeng Hu, Hong Yu, Haihui Sheng, Hengjun Gao, Junxing Huang
Pages: 1061-1067
Published online on: 26 May 2017

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Article

Long non-coding RNA HOXA transcript at the distal tip as a biomarker for gastric cancer

Yuchong Yang, Bin Ma, Ying Yan, Yongxi Song, Peng Gao, Jingxu Sun, Jiajun Wang, Zhenning Wang
Pages: 1068-1072
Published online on: 17 May 2017

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Article

Examination of the predictive factors of the response to whole brain radiotherapy for brain metastases from lung cancer using MRI

Shuri Aoki, Tomonori Kanda, Noriyuki Matsutani, Nobuhiko Seki, Masafumi Kawamura, Shigeru Furui, Hideomi Yamashita
Pages: 1073-1079
Published online on: 26 May 2017

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Article

Curcumol triggers apoptosis of p53 mutant triple-negative human breast cancer MDA-MB 231 cells via activation of p73 and PUMA

Lanzhen Huang, Ang Li, Guanzhen Liao, Feicheng Yang, Jing Yang, Xu Chen, Xiaoshan Jiang
Pages: 1080-1088
Published online on: 29 May 2017

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Article

Sunitinib does not impair natural killer cell function in patients with renal cell carcinoma

Jennifer Moeckel, Nina Staiger, Andreas Mackensen, Norbert Meidenbauer, Evelyn Ullrich
Pages: 1089-1096
Published online on: 17 May 2017

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Article

MicroRNA-215 acts as a tumor suppressor in breast cancer by targeting AKT serine/threonine kinase 1

Jian Yao, Ping Zhang, Jin Li, Wei Xu
Pages: 1097-1104
Published online on: 17 May 2017

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Article

Improved antitumor effect of ionizing radiation in combination with rapamycin for treating nasopharyngeal carcinoma

Di Wang, Lichen Gao, Xueting Liu, Chuang Yuan, Guihua Wang
Pages: 1105-1108
Published online on: 19 May 2017

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Article

Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs

Takuya Nakayama, Megumi Funakoshi‑Tago, Hiroomi Tamura
Pages: 1109-1114
Published online on: 22 May 2017

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Article

Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis

Dong‑Qing Zhang, Chang‑Kuo Zhou, Shou‑Zhen Chen, Yue Yang, Ben‑Kang Shi
Pages: 1115-1122
Published online on: 26 May 2017

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Article

Prospective exploratory study of gemcitabine and S-1 against elderly patients with advanced non-small cell lung cancer

Kyoichi Kaira, Noriko Yanagitani, Noriaki Sunaga, Hisao Imai, Akihiro Ono, Yasuhiko Koga, Takeshi Hisada, Tamotsu Ishizuka, Masanobu Yamada
Pages: 1123-1128
Published online on: 26 May 2017

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Case Report

β-human chorionic gonadotropin-secreting intracranial germ-cell tumor associated with high testosterone in an adult man: A case report

Wen‑Ping Yang, Hung‑Yu Chien, Yi‑Chun Lin
Pages: 1129-1132
Published online on: 19 May 2017

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Article

Characterization of γδ T cells in patients with non-small cell lung cancer

Yi Bao, Li Guo, Juanfen Mo
Pages: 1133-1140
Published online on: 17 May 2017

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Article

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine

Katharina J. Wenger, Marlies Wagner, Se‑Jong You, Kea Franz, Patrick N. Harter, Michael C. Burger, Martin Voss, Michael W. Ronellenfitsch, Emmanouil Fokas, Joachim P. Steinbach, Oliver Bähr
Pages: 1141-1146
Published online on: 25 May 2017

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Article

Effect of thymoquinone on head and neck squamous cell carcinoma cells in vitro: Synergism with radiation

Ulana Kotowski, Gregor Heiduschka, Lorenz Kadletz, Tammer Fahim, Rudolf Seemann, Rainer Schmid, Sven Schneider, Andreas Mitterbauer, Dietmar Thurnher
Pages: 1147-1151
Published online on: 17 May 2017

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Article

Epigallocatechin-3-gallate inhibits growth and induces apoptosis in esophageal cancer cells through the demethylation and reactivation of the p16 gene

Jianchao Meng, Qiang Tong, Xiaobo Liu, Zongtao Yu, Jicai Zhang, Bo Gao
Pages: 1152-1156
Published online on: 25 May 2017

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Article

Antitumor effects of curcumin in human bladder cancer in vitro

Jing Shi, Xu Zhang, Taoping Shi, Hongzhao Li
Pages: 1157-1161
Published online on: 18 May 2017

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Article

Therapy with transcutaneous administration of imiquimod combined with oral administration of sorafenib suppresses renal cell carcinoma growing in an orthotopic mouse model

Takashi Karashima, Keiko Udaka, Mayumi Niimura, Katsuhide Suzuki, Hiroto Osakabe, Tsutomu Shimamoto, Satoshi Fukata, Keiji Inoue, Naoto Kuroda, Motoharu Seiki, Taro Shuin
Pages: 1162-1166
Published online on: 24 May 2017

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Case Report

Diagnostic clue of nodular fasciitis mimicking metastasis in papillary thyroid cancer, mismatching findings on 18F-FDG PET/CT and 123I whole body scan: A case report

Minjung Seo, Misung Kim, Eun Sook Kim, Hongbo Sim, Sungmin Jun, Seol Hoon Park
Pages: 1167-1171
Published online on: 17 May 2017

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Article

Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma

Jingya Chen, Jianhua Wang, Xiao Chen, Yaohui Wang, Zhongqiu Wang, Dake Li
Pages: 1172-1178
Published online on: 22 May 2017

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Article

MAPK inhibitors enhance cell death in pyrogallol-treated human pulmonary fibroblast cells via increasing O2•‑ levels

Bo Ram Han, Woo Hyun Park
Pages: 1179-1185
Published online on: 17 May 2017

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Article

Upregulated expression of MMP-9 in gingival epithelial cells induced by prolonged stimulation with arecoline

Osamu Uehara, Kousuke Takimoto, Tetsuro Morikawa, Fumiya Harada, Rie Takai, Bhoj Raj Adhikari, Ryoko Itatsu, Tomohisa Nakamura, Koki Yoshida, Hirofumi Matsuoka, Hiroki Nagayasu, Ichiro Saito, Malsantha Muthumala, Itsuo Chiba, Yoshihiro Abiko
Pages: 1186-1192
Published online on: 17 May 2017

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Article

Germline DNA copy number variations as potential prognostic markers for non-muscle invasive bladder cancer progression

Yoshiaki Yamamoto, Yutaka Suehiro, Atomu Suzuki, Ryosuke Nawata, Yoshihisa Kawai, Ryo Inoue, Hiroshi Hirata, Hiroaki Matsumoto, Takahiro Yamasaki, Kohsuke Sasaki, Hideyasu Matsuyama
Pages: 1193-1199
Published online on: 24 May 2017

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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