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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2020 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis (Review)

Magdalena Ciążyńska, Igor A. Bednarski, Karolina Wódz, Joanna Narbutt, Aleksandra Lesiak
Pages: 1649-1656
Published online on: 09 January 2020

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Review Open Access

FBW7 in hematological tumors (Review)

Qiaojuan Zhu, Linjun Hu, Yang Guo, Zunqiang Xiao, Qiuran Xu, Xiangmin Tong
Pages: 1657-1664
Published online on: 08 January 2020

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Article Open Access

Aquaporin 5 promotes tumor migration and angiogenesis in non‑small cell lung cancer cell line H1299

Abdalkhalig Elkhider, Bing Wang, Xunli Ouyang, Mahmoud Al‑Azab, Williams Walana, Xiaotong Sun, Han Li, Yawei Tang, Jing Wei, Xia Li
Pages: 1665-1672
Published online on: 07 January 2020

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Article Open Access

Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers

Shou‑Feng Zhao, Xue‑Jing Yin, Wen‑Ju Zhao, Le‑Cui Liu, Zhi‑Peng Wang
Pages: 1673-1682
Published online on: 08 January 2020

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Article Open Access

THBS2, a microRNA‑744‑5p target, modulates MMP9 expression through CUX1 in pancreatic neuroendocrine tumors

Heng Jiao, Lingxiao Zeng, Jianpeng Zhang, Shengsheng Yang, Wenhui Lou
Pages: 1683-1692
Published online on: 09 January 2020

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Article Open Access

PTPN11 hypomethylation is associated with gastric cancer progression

Lele Xu, Cong Zhou, Ranran Pan, Junjian Tang, Jinzhi Wang, Bin Li, Tianyi Huang, Shiwei Duan, Chunfang Xu
Pages: 1693-1700
Published online on: 07 January 2020

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Article Open Access

Role of Bcl‑2 on drug resistance in breast cancer polyploidy‑induced spindle poisons

Bibo Yuan, Juan Hao, Qian Zhang, Yan Wang, Yu Zhu
Pages: 1701-1710
Published online on: 07 January 2020

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Article Open Access

High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma

Liuping Luo, Lihong Chen, Kun Ke, Bixing Zhao, Lili Wang, Cuilin Zhang, Fei Wang, Naishun Liao, Xiaoyuan Zheng, Xiaolong Liu, Yingchao Wang, Jingfeng Liu
Pages: 1711-1720
Published online on: 13 January 2020

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Article Open Access

Prognostic significance of the sub-classification of stage pT3a renal tumors by perinephric and sinus fat invasion

Dongsheng Zhu, Jingyuan Cao, Chao Zhi, Tao Guo, Yuhong Li, Zhiqiang Lang, Gang Li
Pages: 1721-1726
Published online on: 09 January 2020

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Article Open Access

Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance

Tingting Wang, Xiaoyan Lv, Shen Jiang, Shaorong Han, Yanming Wang
Pages: 1727-1734
Published online on: 09 January 2020

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Article Open Access

Increased ski expression levels are associated with a higher risk and poor prognosis in patients with gastrointestinal stromal tumors

Qiu‑Shi Wang, Yu Zhai, Ping Li, Hua‑Liang Xiao, Yuan‑Guo Zhou
Pages: 1735-1740
Published online on: 09 January 2020

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Article Open Access

Diffuse mesothelin expression leads to worse prognosis through enhanced cellular proliferation in colorectal cancer

Satoshi Inoue, Takumi Tsunoda, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Ira Pastan, Kunio Kasugai, Kenji Kasai, Hiroshi Ikeda, Shingo Inaguma
Pages: 1741-1750
Published online on: 10 January 2020

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Article Open Access

Overexpression of miR‑206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases

Xiongfeng Xu, Bo Qiu, Peng Yi, Huajie Li
Pages: 1751-1758
Published online on: 08 January 2020

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Article Open Access

IRF1 association with tumor immune microenvironment and use as a diagnostic biomarker for colorectal cancer recurrence

Yanfang Wu, Shuju Zhang, Jun Yan
Pages: 1759-1770
Published online on: 10 January 2020

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Article Open Access

Fatty acid‑binding protein 5 predicts poor prognosis in patients with uveal melanoma

Yue Xu, Wen‑Hao Xu, Xiao‑Long Yang, Hai‑Liang Zhang, Xiao‑Feng Zhang
Pages: 1771-1780
Published online on: 14 January 2020

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Article Open Access

Comparative mutational analysis of distal colon cancer with rectal cancer

Zhiyong Zhang, Aili Wang, Xuan Tang, Ying Chen, Erjiang Tang, Huihong Jiang
Pages: 1781-1788
Published online on: 08 January 2020

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Article Open Access

Expression pattern of p‑Smad2/Smad4 as a predictor of survival in invasive breast ductal carcinoma

Nannan Liu, Dongxue Qi, Jing Jiang, Jihong Zhang, Chunyan Yu
Pages: 1789-1798
Published online on: 13 January 2020

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Article Open Access

The oncogenic role of microRNA‑500a in colorectal cancer

Yang Li, Zhong Chen
Pages: 1799-1805
Published online on: 10 January 2020

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Article Open Access

MicroRNA‑139‑5p inhibits cell viability, migration and invasion and suppresses tumor growth by targeting HDGF in non‑small cell lung cancer Retraction in /10.3892/ol.2023.14090

Zuxiong Zhang, Weizhi Li, Damei Jiang, Chi Liu, Zhenghong Lai
Pages: 1806-1814
Published online on: 13 January 2020

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Article Open Access

High expression of citron kinase predicts poor prognosis of prostate cancer

Junnan Liu, Jianguo Dou, Wujiao Wang, Hengchuan Liu, Yunlang Qin, Qixin Yang, Wencheng Jiang, Yong Liang, Yuejiang Liu, Jiang He, Li Mai, Ying Li, Delin Wang
Pages: 1815-1823
Published online on: 07 January 2020

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Article Open Access

Total flavonoids suppress lung cancer growth via the COX‑2‑mediated Wnt/β‑catenin signaling pathway Retraction in /10.3892/ol.2024.14212

Lei Han, Shu Fang, Guangtao Li, Minghuan Wang, Renzhi Yu
Pages: 1824-1830
Published online on: 09 January 2020

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Article Open Access

Distinct expression and prognostic values of the replication protein A family in gastric cancer

Yujie Zhang, Chaoran Yu
Pages: 1831-1841
Published online on: 07 January 2020

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Article Open Access

Expression and clinical significance of MAPK and EGFR in triple‑negative breast cancer

Weihua Jiang, Xiaowen Wang, Chenguang Zhang, Laiti Xue, Liang Yang
Pages: 1842-1848
Published online on: 09 January 2020

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Article Open Access

Long non‑coding RNA‑ZNF281 promotes cancer cell migration and invasion in gastric cancer via downregulation of microRNA‑124

Hengling Gao, Peizhe Li, Yingrui Hei, Shuliang Li, Jinkai Wang, Xukun Lv, Jianxian Zhang
Pages: 1849-1855
Published online on: 10 January 2020

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Article Open Access

ADAM9: A novel player in vestibular schwannoma pathogenesis

Maria Breun, Alexandra Schwerdtfeger, Donato Daniel Martellotta, Almuth F. Kessler, Camelia M. Monoranu, Cordula Matthies, Mario Löhr, Carsten Hagemann
Pages: 1856-1864
Published online on: 14 January 2020

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Article Open Access

Quantitative analysis of metabolic parameters at 18F‑fluorodeoxyglucose positron emission tomography in predicting malignant potential of anterior mediastinal tumors

Toshiki Yajima, Akira Mogi, Kimihiro Shimizu, Takayuki Kosaka, Yoichi Ohtaki, Kai Obayashi, Seshiru Nakazawa, Takahito Nakajima, Yoshito Tsushima, Ken Shirabe
Pages: 1865-1871
Published online on: 09 January 2020

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Article Open Access

Pharmacokinetic evaluation and antitumor potency of liposomal nanoparticle encapsulated cisplatin targeted to CD24‑positive cells in ovarian cancer

Keisuke Ashihara, Yoshito Terai, Tomohito Tanaka, Yoshimichi Tanaka, Satoe Fujiwara, Kazuya Maeda, Satoshi Tunetoh, Hiroshi Sasaki, Masami Hayashi, Masahide Ohmichi
Pages: 1872-1880
Published online on: 09 January 2020

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Article Open Access

Identification of crucial genes and pathways associated with colorectal cancer by bioinformatics analysis

Xiaoqun Liu, Xiangdong Liu, Tiankui Qiao, Wei Chen
Pages: 1881-1889
Published online on: 09 January 2020

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Article Open Access

Clinicopathological analysis of 250 cases of pituitary adenoma under the new WHO classification

Jiayu Liu, Yuhao He, Xuebin Zhang, Xiaoling Yan, Ying Huang
Pages: 1890-1898
Published online on: 08 January 2020

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Article Open Access

Long non‑coding RNA EGFR‑AS1 sponges micorRNA‑381 to upregulate ROCK2 in bladder cancer

Shouxian Yuan, Xiuhua Luan, Haixia Chen, Xiuqing Shi, Xiangkai Zhang
Pages: 1899-1905
Published online on: 09 January 2020

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Article Open Access

Deregulation of cell adhesion molecules is associated with progression and poor outcomes in endometrial cancer: Analysis of The Cancer Genome Atlas data

Xiangjun He, Shu Lei, Qi Zhang, Liping Ma, Na Li, Jianliu Wang
Pages: 1906-1914
Published online on: 13 January 2020

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Article Open Access

Identification of candidate RNA signatures in triple‑negative breast cancer by the construction of a competing endogenous RNA network with integrative analyses of Gene Expression Omnibus and The Cancer Genome Atlas data

Ping Yan, Lingfeng Tang, Li Liu, Gang Tu
Pages: 1915-1927
Published online on: 10 January 2020

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Article Open Access

Prognostic value of key genes of the JAK‑STAT signaling pathway in patients with cutaneous melanoma

Fuqiang Pan, Qiaoqi Wang, Sizhu Li, Rui Huang, Xiangkun Wang, Xiwen Liao, Haiyan Mo, Liming Zhang, Xiang Zhou
Pages: 1928-1946
Published online on: 10 January 2020

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Article Open Access

Prognosis of ovarian clear cell cancer compared with other epithelial cancer types: A population‑based analysis

Hong Liu, Yanbo Xu, Jiali Ji, Rongrong Dong, Huiqing Qiu, Xiaolan Dai
Pages: 1947-1957
Published online on: 07 January 2020

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Article

MicroRNA‑107 may regulate lung cancer cell proliferation and apoptosis by targeting TP53 regulated inhibitor of apoptosis 1

Peng Cai, Jingjing Li, Guiming Chen, Bing Peng, Liuyang Yu, Bolin Zhao, Yi Yu
Pages: 1958-1966
Published online on: 07 January 2020

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Article

Exosomal microRNA‑210 is a potentially non‑invasive biomarker for the diagnosis and prognosis of glioma

Fengming Lan, Xiao Yue, Tingyi Xia
Pages: 1967-1974
Published online on: 07 January 2020

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Article

Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation

Yiling Zhang, Ningning Cui, Gang Zheng
Pages: 1975-1984
Published online on: 08 January 2020

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Article

Innovative analysis of distant metastasis in differentiated thyroid cancer

Danyang Chen, Lei Huang, Sichao Chen, Yihui Huang, Di Hu, Wen Zeng, Min Wang, Wei Zhou, Haifeng Feng, Wei Wei, Chao Zhang, Zeming Liu, Liang Guo
Pages: 1985-1992
Published online on: 15 January 2020

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Article

Overexpression of long non‑coding RNA cancer susceptibility 11 is involved in the development of chemoresistance to carboplatin in hepatocellular carcinoma

Haidong Liu, Tao Liu, Yong Zhou, Xinwen Song, Rendong Wei
Pages: 1993-1998
Published online on: 08 January 2020

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Article

Akt inhibitor MK‑2206 reduces pancreatic cancer cell viability and increases the efficacy of gemcitabine

Zhanshan Wang, Guangtao Luo, Zhengjun Qiu
Pages: 1999-2004
Published online on: 14 January 2020

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Article

Incidental findings in the thyroid gland on computed tomography images of the oral and maxillofacial region

Abdullah Khasawneh, Yohei Takeshita, Miki Hisatomi, Toshiyuki Kawazu, Mariko Fujita, Shunsuke Okada, Yuri Namba, Yudai Shimizu, Yoshinobu Yanagi, Junichi Asaumi
Pages: 2005-2010
Published online on: 13 January 2020

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Article

Scinderin suppresses cell proliferation and predicts the poor prognosis of hepatocellular carcinoma

Bin Zhou, Tian‑Wei Chen, Ya‑Bo Jiang, Xu‑Biao Wei, Chong‑De Lu, Jing‑Jing Li, Dong Xie, Shu‑Qun Cheng
Pages: 2011-2020
Published online on: 08 January 2020

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Article

Role of HSP27 in the multidrug sensitivity and resistance of colon cancer cells

Zhengyong Liu, Yi Liu, Yupeng Long, Baohua Liu, Xiangfeng Wang
Pages: 2021-2027
Published online on: 07 January 2020

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Article Open Access

Limited efficacy of pixantrone in refractory diffuse large B-cell lymphoma

Aleksander Novakovic, Lucka Boltezar, Barbara Jezersek Novakovic
Pages: 2028-2034
Published online on: 10 January 2020

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Article

Long non‑coding RNA LINC00152 acts as a sponge of miRNA‑193b‑3p to promote tongue squamous cell carcinoma progression

Xiuhua Li, Bing Rui, Yongbing Cao, Xiaojian Gong, Hongjiao Li
Pages: 2035-2042
Published online on: 13 January 2020

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Article

Hepatitis B virus upregulates cellular inhibitor of apoptosis protein 2 expression via the PI3K/AKT/NF‑κB signaling pathway in liver cancer

Jianping Lian, Yuanhua Zou, Ling Huang, Hao Cheng, Kai Huang, Junquan Zeng, Longhua Chen
Pages: 2043-2052
Published online on: 08 January 2020

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Article

Downregulation of extracellular vesicle microRNA‑101 derived from bone marrow mesenchymal stromal cells in myelodysplastic syndrome with disease progression

Yuu Saitoh, Tomohiro Umezu, Satoshi Imanishi, Michiyo Asano, Seiichiro Yoshizawa, Seiichiro Katagiri, Tamiko Suguro, Hiroaki Fujimoto, Daigo Akahane, Chiaki Kobayashi‑Kawana, Junko H. Ohyashiki, Kazuma Ohyashiki
Pages: 2053-2061
Published online on: 09 January 2020

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Article Open Access

Elevated expression of exosomal microRNA‑21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip

Xiaofan Pu, Guoping Ding, Mingjie Wu, Senhao Zhou, Shengnan Jia, Liping Cao
Pages: 2062-2070
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Alejandro Schcolnik‑Cabrera, Guadalupe Dominguez‑Gómez, Alma Chávez‑Blanco, Marisol Ramírez‑Yautentzi, Rocío Morales‑Bárcenas, José Díaz‑Chávez, Lucía Taja‑Chayeb, Alfonso Dueñas‑González
Pages: 2071-2071
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

Min Yong, Tinghe Yu, Si Tian, Shuaibin Liu, Jiao Xu, Jianguo Hu, Lina Hu
Pages: 2072-2072
Published online on: 09 January 2020

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Review Open Access

Lymphedema in survivors of breast cancer (Review)

Lin He, Huili Qu, Qian Wu, Yuhua Song
Pages: 2085-2096
Published online on: 16 January 2020

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Article Open Access

Curative effect of methotrexate combined with teniposide in the treatment of primary central nervous system lymphoma

Yi‑Xia Wang, Yan Huang, Xiao‑Ping Xu, Bo‑Bin Chen, Zhi‑Guang Lin, Yan Ma, Tian‑Ling Ding, Qian Wang
Pages: 2097-2106
Published online on: 22 January 2020

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Article Open Access

TSP‑1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar

Wende Yang, Wei Li, Fan Pan, Xiao‑Yan Yang, Xiaoxu Zhao, Li Qin, Yunlong Pan
Pages: 2107-2114
Published online on: 21 January 2020

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Article Open Access

HSP90AA1, ADRB2, TBL1XR1 and HSPB1 are chronic obstructive pulmonary disease‑related genes that facilitate squamous cell lung cancer progression

Lijing Wang, Hongjun Zhao, Lemeng Zhang, Hui Luo, Qiong Chen, Xiaoxia Zuo
Pages: 2115-2122
Published online on: 17 January 2020

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Article Open Access

Effect of apigenin on whole transcriptome profile of TNFα‑activated MDA‑MB‑468 triple negative breast cancer cells

David Bauer, Elizabeth Mazzio, Aaron Hilliard, Ebenezer T. Oriaku, Karam F. A. Soliman
Pages: 2123-2132
Published online on: 22 January 2020

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Article Open Access

AXIN2 and SNAIL expression predict the risk of recurrence in cutaneous squamous cell carcinoma after Mohs micrographic surgery

Guohua Zhao, Ki‑Yeol Kim, Zhenlong Zheng, Yeongjoo Oh, Dae San Yoo, Myung Eun Lee, Kee Yang Chung, Mi Ryung Roh, Zhehu Jin
Pages: 2133-2140
Published online on: 21 January 2020

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Article Open Access

High expression of interleukin‑enhancer binding factor 3 predicts poor prognosis in patients with lung adenocarcinoma

Zhangyan Xu, Hua Huang, Xing Li, Cheng Ji, Yifei Liu, Xiaojuan Liu, Jun Zhu, Zhendong Wang, Haijian Zhang, Jiahai Shi
Pages: 2141-2152
Published online on: 22 January 2020

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Article Open Access

Identification of glutathione S‑transferase π 1 as a prognostic proteomic biomarker for multiple myeloma using proteomic profiling

Jing Zhao, Meihua Wang, Pengcheng He, Ying Chen, Xiaoning Wang, Mei Zhang
Pages: 2153-2162
Published online on: 21 January 2020

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Article Open Access

ZW10 interacting kinetochore protein may serve as a prognostic biomarker for human breast cancer: An integrated bioinformatics analysis

Han‑Ning Li, Wei‑Hong Zheng, Ya‑Ying Du, Ge Wang, Meng‑Lu Dong, Zhi‑Fang Yang, Xing‑Rui Li
Pages: 2163-2174
Published online on: 24 January 2020

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Article Open Access

Integrated analysis of circular RNA‑associated ceRNA network in pancreatic ductal adenocarcinoma

Wei Song, Wen‑Jie Wang, Tao Fu, Lei Chen, Dong‑Liu Miao
Pages: 2175-2184
Published online on: 16 January 2020

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Article Open Access

Competing endogenous RNA network analysis reveals potential long non‑coding RNAs as predictive biomarkers of gastric cancer

Sanfei Peng, Xiangyang Yin, Yizheng Zhang, Wunan Mi, Tong Li, Yang Yu, Jianwu Jiang, Qi Liu, Yang Fu
Pages: 2185-2196
Published online on: 24 January 2020

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Article Open Access

Analysis of the methylation of CpG islands in the CDO1, TAC1 and CHFR genes in pancreatic ductal cancer

Hiroshi Maekawa, Tomoaki Ito, Hajime Orita, Tomoyuki Kushida, Mutsumi Sakurada, Koichi Sato, Alicia Hulbert, Malcolm V. Brock
Pages: 2197-2204
Published online on: 23 January 2020

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Simple scoring system for prediction of hepatocellular carcinoma occurrence after hepatitis C virus eradication by direct‑acting antiviral treatment: All Kagawa Liver Disease Group Study

Joji Tani, Asahiro Morishita, Teppei Sakamoto, Kei Takuma, Mai Nakahara, Koji Fujita, Kyoko Oura, Tomoko Tadokoro, Shima Mimura, Takako Nomura, Hirohito Yoneyama, Hideki Kobara, Takashi Himoto, Akemi Tsutsui, Tomonori Senoh, Takuya Nagano, Chikara Ogawa, Akio Moriya, Akihiro Deguchi, Kouichi Takaguchi, Tsutomu Masaki
Pages: 2205-2212
Published online on: 23 January 2020

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MicroRNA‑22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c‑Myc binding protein, and the subsequent reduction in hTERT expression

Mayumi Nakamura, Masami Hayashi, Hiromi Konishi, Misa Nunode, Keisuke Ashihara, Hiroshi Sasaki, Yoshito Terai, Masahide Ohmichi
Pages: 2213-2222
Published online on: 23 January 2020

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Secretagogin, a marker for neuroendocrine cells, is more sensitive and specific in large cell neuroendocrine carcinoma compared with the markers CD56, CgA, Syn and Napsin A

Yunlong Dong, Yongwen Li, Renwang Liu, Ying Li, Hongbing Zhang, Hongyu Liu, Jun Chen
Pages: 2223-2230
Published online on: 23 January 2020

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Association of serum levels of deoxyribose 1‑phosphate and S‑lactoylglutathione with neoadjuvant chemotherapy sensitivity in patients with gastric cancer: A metabolomics study

Daguang Wang, Wei Li, Lei Yin, Yechao Du, Shaopeng Zhang, Jian Suo
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Published online on: 24 January 2020

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Flotillin‑2 predicts poor prognosis and promotes tumor invasion in intrahepatic cholangiocarcinoma

Zhiying Xu, Tao Wang, Haiyang Song, Xuewen Jiang
Pages: 2243-2250
Published online on: 24 January 2020

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Identification of circulating tumor DNA using a targeted 545‑gene next generation sequencing panel in patients with gastric cancer

Jing Lan, Yaping Lu, Yanfang Guan, Lianpeng Chang, Zhengyuan Yu, Haixin Qian
Pages: 2251-2257
Published online on: 16 January 2020

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Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5‑FU

Takuto Kawahata, Kohichi Kawahara, Michiko Shimokawa, Akie Sakiyama, Takehiro Shiraishi, Kentaro Minami, Masatatsu Yamamoto, Yoshinari Shinsato, Kazunari Arima, Toshiyuki Hamada, Tatsuhiko Furukawa
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miR‑202 functions as a tumor suppressor in hepatocellular carcinoma by targeting HK2

Jiangang Wang, Jili Chen, Fang Sun, Zhiwei Wang, Wenfang Xu, Yafeng Yu, Feng Ding, Huajiang Shen
Pages: 2265-2271
Published online on: 23 January 2020

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MARCKSL1 promotes the proliferation, migration and invasion of lung adenocarcinoma cells

Wenjun Liang, Ruichen Gao, Mingxia Yang, Xiaohua Wang, Kewei Cheng, Xuejun Shi, Chen He, Yemei Li, Yuying Wu, Lei Shi, Jingtao Chen, Xiaowei Yu
Pages: 2272-2280
Published online on: 17 January 2020

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Long non‑coding (lnc)RNA PAPAS overexpression inhibits tumor growth in papillary thyroid carcinoma by downregulating lncRNA HOTTIP

Juan  Xiao, Zhaowei  Bing, Ge  Xiao, Yang  Guan, Jian Luan
Pages: 2281-2285
Published online on: 21 January 2020

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Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer

Kazumasa Kure, Masaki Hosoya, Takae Ueyama, Midori Fukaya, Kiichi Sugimoto, Yuichi Tomiki, Takashi Ohnaga, Kazuhiro Sakamoto, Hiromitsu Komiyama
Pages: 2286-2294
Published online on: 23 January 2020

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Integrated bioinformatics analysis of the association between apolipoprotein E expression and patient prognosis in papillary thyroid carcinoma

Qunguang Jiang, Wenqian Feng, Chengfeng Xiong, Yunxia Lv
Pages: 2295-2305
Published online on: 17 January 2020

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γ‑Klotho is correlated with resistance to docetaxel in castration‑resistant prostate cancer

Kenta Onishi, Makito Miyake, Shunta Hori, Sayuri Onishi, Kota Iida, Yosuke Morizawa, Yoshihiro Tatsumi, Yasushi Nakai, Nobumichi Tanaka, Kiyohide Fujimoto
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Published online on: 16 January 2020

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Detection of high‑risk human papillomavirus DNA in sentinel lymph nodes of patients with cervical cancer

Yan Lu, Xun Xu, Xiu‑Hong Nong, De‑Sheng Yao
Pages: 2317-2325
Published online on: 23 January 2020

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ADH7, miR‑3065 and LINC01133 are associated with cervical cancer progression in different age groups

Shengdi Ding, Xiaohong Huang, Junmei Zhu, Bing Xu, Limin Xu, Donghua Gu, Wenyuan Zhang
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Published online on: 24 January 2020

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Long noncoding RNA MACC1‑AS1 is a potential sponge of microRNA‑34a in cervical squamous cell carcinoma and upregulates cyclin‑dependent kinase 6

Jieqiong Jin, Xuemei Chen, Jing Chen, Xin Geng
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Published online on: 24 January 2020

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Feasibility of primary human cell cultures as a model for adamantinomatous craniopharyngioma research: Evidence from RNA‑Seq analysis

Pei‑Dong Zhang, Chao‑Hu Wang, Jun Fan, Jun‑Xiang Peng, Jun Pan, Song‑Tao Qi, Yi Liu
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Published online on: 16 January 2020

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Impact of cancer rehabilitation on the prognosis of patients with hepatocellular carcinoma

Ryuki Hashida, Takumi Kawaguchi, Shunji Koya, Keisuke Hirota, Norihiro Goshima, Teruhito Yoshiyama, Takashi Otsuka, Masafumi Bekki, Sohei Iwanaga, Dan Nakano, Takashi Niizeki, Hiroo Matsuse, Atsushi Kawaguchi, Naoto Shiba, Takuji Torimura
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Frequency of somatic mutations in TERT promoter, TP53 and CTNNB1 genes in patients with hepatocellular carcinoma from Southern Italy

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Published online on: 22 January 2020

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Comparison of the clinicopathological features and prognoses of patients with schistosomal and nonschistosomal colorectal cancer

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Published online on: 22 January 2020

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Relationship between platelet‑based models and the prognosis of patients with malignant hepatic tumors

Chen‑Liang Hu, Qian‑Cheng Du, Zhi‑Xin Wang, Ming‑Quan Pang, Yan‑Yan Wang, Ying‑Yu Li, Ying Zhou, Hai‑Jiu Wang, Hai‑Ning Fan
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Ethyl 2‑anilino‑4‑oxo‑4,5‑dihydrofuran‑3‑carboxylate exhibits anti‑proliferative activity and induces apoptosis in promyelocytic leukemia HL‑60 cells

An‑Cheng Huang, Chen‑Sheng Lin, Jin‑Cherng Lien, Hsueh‑Chou Lai, Wei‑Hua Lin, Cheng‑Wen Lin
Pages: 2397-2403
Published online on: 23 January 2020

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Accumulation of stabilin‑1 positive macrophages in the early stage of gastric cancer is associated with short cumulative survival

Shui‑Ping Yin, Yi Gao, Xu‑Shi Xie, Dan‑Dan Xu, Vladimir Riabov, Wei‑Dong Du
Pages: 2404-2412
Published online on: 16 January 2020

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Expression of molecules of the Wnt pathway and of E‑cadherin in the etiopathogenesis of human thymomas

Prokop Vodicka, Lenka Krskova, Igor Odintsov, Ludmila Krizova, Eva Sedlackova, Jan Schutzner, Josef Zamecnik
Pages: 2413-2421
Published online on: 23 January 2020

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Breast cancer stem cell RNA‑pulsed dendritic cells enhance tumor cell killing by effector T cells 

Nuttavut Sumransub, Niphat Jirapongwattana, Pranisa Jamjuntra, Suyanee Thongchot, Thaweesak Chieochansin, Pa‑Thai Yenchitsomanus, Peti Thuwajit, Malee Warnnissorn, Pornchai O‑Charoenrat, Chanitra Thuwajit
Pages: 2422-2430
Published online on: 23 January 2020

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Expression levels and associations of five long non‑coding RNAs in gastric cancer and their clinical significance

Helen Barong Binang, Yun‑Shan Wang, Marlvin Anemey Tewara, Lutao Du, Shuang Shi, Ning Li, Ariston Gabriel Abakundana Nsenga, Chuanxin Wang
Pages: 2431-2445
Published online on: 16 January 2020

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Clinicopathological characteristics and genetic analysis of pulmonary carcinoid tumors: A single‑center retrospective cohort study and literature review

Xiongfei Li, Yuelong Hou, Tao Shi, Yue He, Dian Ren, Zuoqing Song, Sen Wei, Gang Chen, Jun Chen, Song Xu
Pages: 2446-2456
Published online on: 24 January 2020

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Association between interleukin‑36γ and tumor progression in non‑small cell lung cancer

Lin Liu, Honghong He, Dan Xu, Yuehua Feng, Huijun Zhou, Liyan Shi, Yanzheng Gu, Jian Wang, Yibei Zhu
Pages: 2457-2465
Published online on: 17 January 2020

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CDCA2 acts as an oncogene and induces proliferation of clear cell renal cell carcinoma cells

Fang Li, Huahua Zhang, Qian Li, Fei Wu, Yu Wang, Zhenzhen Wang, Xiaofei Wang, Chen Huang
Pages: 2466-2474
Published online on: 21 January 2020

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Article

Long non‑coding RNA ELF3‑antisense RNA 1 promotes osteosarcoma cell proliferation by upregulating Kruppel‑like factor 12 potentially via methylation of the microRNA‑205 gene

Jianmin Yuan, Jianhui Kang, Min Yang
Pages: 2475-2480
Published online on: 16 January 2020

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Article

PD‑L1 expression in malignant melanomas of the skin and gastrointestinal tract

Michiko Akiyama, Yoko Matsuda, Tomio Arai, Hidehisa Saeki
Pages: 2481-2488
Published online on: 21 January 2020

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Long noncoding RNA PLAC2 regulates PTEN in retinoblastoma and participates in the regulation of cancer cell apoptosis

Ling Song, Yueqin Qi, Ming Lin
Pages: 2489-2494
Published online on: 17 January 2020

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Article

C‑X‑C motif receptor 3A enhances proliferation and invasiveness of colorectal cancer cells, and is mediated by C‑X‑C motif ligand 10

Eriko Nozaki, Takaaki Kobayashi, Hiroaki Ohnishi, Kouki Ohtsuka, Tadahiko Masaki, Takashi Watanabe, Masanori Sugiyama
Pages: 2495-2501
Published online on: 21 January 2020

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Article

Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine

Ahmed S. K. Al‑Khafaji, Paschalia Pantazi, Amelia Acha‑Sagredo, Andrew Schache, Janet M. Risk, Richard J. Shaw, Triantafillos Liloglou
Pages: 2502-2507
Published online on: 23 January 2020

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Article

Inhibiting the Src/STAT3 signaling pathway contributes to the anti‑melanoma mechanisms of dioscin

Yu‑Xi Liu, Bo‑Wen Xu, Ying‑Jie Chen, Xiu‑Qiong Fu, Pei‑Li Zhu, Jing‑Xuan Bai, Ji‑Yao Chou, Cheng‑Le Yin, Jun‑Kui Li, Ya‑Ping Wang, Jia‑Ying Wu, Ying Wu, Kam‑Kwan Chan, Chun Liang, Zhi‑Ling Yu
Pages: 2508-2514
Published online on: 17 January 2020

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Article

Stereotactic body radiotherapy feasibility for patients with peripheral stage Ι lung cancer and poor pulmonary function

Aiko Koba, Kazuhiko Hayashi, Osamu Suzuki, Yoshifumi Kawaguchi, Kazuhiko Ogawa, Masashi Chatani
Pages: 2515-2521
Published online on: 22 January 2020

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Article

Triple negative endometrial cancer: Incidence and prognosis in a monoinstitutional series of 220 patients

Rosa Porzio, Claudia Cordini, Anna Maria Rodolfi, Francesca Brigati, Alessandro Ubiali, Manuela Proietto, Camilla Di Nunzio, Luigi Cavanna
Pages: 2522-2526
Published online on: 22 January 2020

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Article

Changes of serum miR-223-3p in patients with oral cancer treated with TPF regimen and the prognosis

Chunru Li, Yao Feng, Weiran Shao
Pages: 2527-2532
Published online on: 24 January 2020

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Article

Effect of nalbuphine on patient controlled intravenous analgesia after radical resection of colon cancer

Qi Jiang, Rongfang Zhang, Tao Liu
Pages: 2533-2538
Published online on: 24 January 2020

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Article

Efficacy analysis of trastuzumab, carboplatin and docetaxel in HER‑2‑positive breast cancer patients

Di Wu, Liangfa Xiong
Pages: 2539-2546
Published online on: 24 January 2020

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Long-chain non-coding RNA GACAT1 promotes development and progression of breast cancer by targeting microRNA-875-3p

Qinghua Wang, Jie Xue, Qingfang Ren, Xiaona Li, Xiaoli Qiu
Pages: 2547-2553
Published online on: 24 January 2020

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Article

Clinical efficacy of platelet transfusion therapy in patients with leukemia and analysis of risk factors for ineffective transfusion

Li Chen, Hao Zhou, Bo Guo , Zheng Guan
Pages: 2554-2561
Published online on: 24 January 2020

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Article

Correlation of APOBEC3G expression with liver function indexes of patients with chronic hepatitis B and comparison in chronic hepatitis B, liver cirrhosis and liver cancer

Lina Ni, Chuanbao Li, Yingbo Li
Pages: 2562-2567
Published online on: 24 January 2020

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Effect of miR‑205 on proliferation and migration of thyroid cancer cells by targeting CCNB2 and the mechanism

Xin Wang, Haomin Zhang, Kai Jiao, Chunyang Zhao, Hailong Liu, Qinghong Meng, Zhao Wang, Chunling Feng, Yuanchun Li
Pages: 2568-2574
Published online on: 24 January 2020

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Review Open Access

Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Article Open Access

Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Article Open Access

Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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Article Open Access

CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Article Open Access

Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Review Open Access

Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Article Open Access

Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Article Open Access

Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Review Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Article Open Access

Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Article Open Access

Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Article Open Access

Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Review Open Access

Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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Article Open Access

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec‑Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Article Open Access

Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara‑Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum‑Quiroz, Noemí García‑Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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