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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2020 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis (Review)

Magdalena Ciążyńska, Igor A. Bednarski, Karolina Wódz, Joanna Narbutt, Aleksandra Lesiak
Pages: 1649-1656
Published online on: 09 January 2020

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Review Open Access

FBW7 in hematological tumors (Review)

Qiaojuan Zhu, Linjun Hu, Yang Guo, Zunqiang Xiao, Qiuran Xu, Xiangmin Tong
Pages: 1657-1664
Published online on: 08 January 2020

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Article Open Access

Aquaporin 5 promotes tumor migration and angiogenesis in non‑small cell lung cancer cell line H1299

Abdalkhalig Elkhider, Bing Wang, Xunli Ouyang, Mahmoud Al‑Azab, Williams Walana, Xiaotong Sun, Han Li, Yawei Tang, Jing Wei, Xia Li
Pages: 1665-1672
Published online on: 07 January 2020

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Article Open Access

Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers

Shou‑Feng Zhao, Xue‑Jing Yin, Wen‑Ju Zhao, Le‑Cui Liu, Zhi‑Peng Wang
Pages: 1673-1682
Published online on: 08 January 2020

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Article Open Access

THBS2, a microRNA‑744‑5p target, modulates MMP9 expression through CUX1 in pancreatic neuroendocrine tumors

Heng Jiao, Lingxiao Zeng, Jianpeng Zhang, Shengsheng Yang, Wenhui Lou
Pages: 1683-1692
Published online on: 09 January 2020

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Article Open Access

PTPN11 hypomethylation is associated with gastric cancer progression

Lele Xu, Cong Zhou, Ranran Pan, Junjian Tang, Jinzhi Wang, Bin Li, Tianyi Huang, Shiwei Duan, Chunfang Xu
Pages: 1693-1700
Published online on: 07 January 2020

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Article Open Access

Role of Bcl‑2 on drug resistance in breast cancer polyploidy‑induced spindle poisons

Bibo Yuan, Juan Hao, Qian Zhang, Yan Wang, Yu Zhu
Pages: 1701-1710
Published online on: 07 January 2020

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Article Open Access

High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma

Liuping Luo, Lihong Chen, Kun Ke, Bixing Zhao, Lili Wang, Cuilin Zhang, Fei Wang, Naishun Liao, Xiaoyuan Zheng, Xiaolong Liu, Yingchao Wang, Jingfeng Liu
Pages: 1711-1720
Published online on: 13 January 2020

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Article Open Access

Prognostic significance of the sub-classification of stage pT3a renal tumors by perinephric and sinus fat invasion

Dongsheng Zhu, Jingyuan Cao, Chao Zhi, Tao Guo, Yuhong Li, Zhiqiang Lang, Gang Li
Pages: 1721-1726
Published online on: 09 January 2020

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Article Open Access

Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance

Tingting Wang, Xiaoyan Lv, Shen Jiang, Shaorong Han, Yanming Wang
Pages: 1727-1734
Published online on: 09 January 2020

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Article Open Access

Increased ski expression levels are associated with a higher risk and poor prognosis in patients with gastrointestinal stromal tumors

Qiu‑Shi Wang, Yu Zhai, Ping Li, Hua‑Liang Xiao, Yuan‑Guo Zhou
Pages: 1735-1740
Published online on: 09 January 2020

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Article Open Access

Diffuse mesothelin expression leads to worse prognosis through enhanced cellular proliferation in colorectal cancer

Satoshi Inoue, Takumi Tsunoda, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Ira Pastan, Kunio Kasugai, Kenji Kasai, Hiroshi Ikeda, Shingo Inaguma
Pages: 1741-1750
Published online on: 10 January 2020

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Article Open Access

Overexpression of miR‑206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases

Xiongfeng Xu, Bo Qiu, Peng Yi, Huajie Li
Pages: 1751-1758
Published online on: 08 January 2020

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Article Open Access

IRF1 association with tumor immune microenvironment and use as a diagnostic biomarker for colorectal cancer recurrence

Yanfang Wu, Shuju Zhang, Jun Yan
Pages: 1759-1770
Published online on: 10 January 2020

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Article Open Access

Fatty acid‑binding protein 5 predicts poor prognosis in patients with uveal melanoma

Yue Xu, Wen‑Hao Xu, Xiao‑Long Yang, Hai‑Liang Zhang, Xiao‑Feng Zhang
Pages: 1771-1780
Published online on: 14 January 2020

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Article Open Access

Comparative mutational analysis of distal colon cancer with rectal cancer

Zhiyong Zhang, Aili Wang, Xuan Tang, Ying Chen, Erjiang Tang, Huihong Jiang
Pages: 1781-1788
Published online on: 08 January 2020

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Article Open Access

Expression pattern of p‑Smad2/Smad4 as a predictor of survival in invasive breast ductal carcinoma

Nannan Liu, Dongxue Qi, Jing Jiang, Jihong Zhang, Chunyan Yu
Pages: 1789-1798
Published online on: 13 January 2020

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Article Open Access

The oncogenic role of microRNA‑500a in colorectal cancer

Yang Li, Zhong Chen
Pages: 1799-1805
Published online on: 10 January 2020

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Article Open Access

MicroRNA‑139‑5p inhibits cell viability, migration and invasion and suppresses tumor growth by targeting HDGF in non‑small cell lung cancer Retraction in /10.3892/ol.2023.14090

Zuxiong Zhang, Weizhi Li, Damei Jiang, Chi Liu, Zhenghong Lai
Pages: 1806-1814
Published online on: 13 January 2020

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Article Open Access

High expression of citron kinase predicts poor prognosis of prostate cancer

Junnan Liu, Jianguo Dou, Wujiao Wang, Hengchuan Liu, Yunlang Qin, Qixin Yang, Wencheng Jiang, Yong Liang, Yuejiang Liu, Jiang He, Li Mai, Ying Li, Delin Wang
Pages: 1815-1823
Published online on: 07 January 2020

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Article Open Access

Total flavonoids suppress lung cancer growth via the COX‑2‑mediated Wnt/β‑catenin signaling pathway Retraction in /10.3892/ol.2024.14212

Lei Han, Shu Fang, Guangtao Li, Minghuan Wang, Renzhi Yu
Pages: 1824-1830
Published online on: 09 January 2020

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Article Open Access

Distinct expression and prognostic values of the replication protein A family in gastric cancer

Yujie Zhang, Chaoran Yu
Pages: 1831-1841
Published online on: 07 January 2020

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Article Open Access

Expression and clinical significance of MAPK and EGFR in triple‑negative breast cancer

Weihua Jiang, Xiaowen Wang, Chenguang Zhang, Laiti Xue, Liang Yang
Pages: 1842-1848
Published online on: 09 January 2020

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Article Open Access

Long non‑coding RNA‑ZNF281 promotes cancer cell migration and invasion in gastric cancer via downregulation of microRNA‑124

Hengling Gao, Peizhe Li, Yingrui Hei, Shuliang Li, Jinkai Wang, Xukun Lv, Jianxian Zhang
Pages: 1849-1855
Published online on: 10 January 2020

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Article Open Access

ADAM9: A novel player in vestibular schwannoma pathogenesis

Maria Breun, Alexandra Schwerdtfeger, Donato Daniel Martellotta, Almuth F. Kessler, Camelia M. Monoranu, Cordula Matthies, Mario Löhr, Carsten Hagemann
Pages: 1856-1864
Published online on: 14 January 2020

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Article Open Access

Quantitative analysis of metabolic parameters at 18F‑fluorodeoxyglucose positron emission tomography in predicting malignant potential of anterior mediastinal tumors

Toshiki Yajima, Akira Mogi, Kimihiro Shimizu, Takayuki Kosaka, Yoichi Ohtaki, Kai Obayashi, Seshiru Nakazawa, Takahito Nakajima, Yoshito Tsushima, Ken Shirabe
Pages: 1865-1871
Published online on: 09 January 2020

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Article Open Access

Pharmacokinetic evaluation and antitumor potency of liposomal nanoparticle encapsulated cisplatin targeted to CD24‑positive cells in ovarian cancer

Keisuke Ashihara, Yoshito Terai, Tomohito Tanaka, Yoshimichi Tanaka, Satoe Fujiwara, Kazuya Maeda, Satoshi Tunetoh, Hiroshi Sasaki, Masami Hayashi, Masahide Ohmichi
Pages: 1872-1880
Published online on: 09 January 2020

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Article Open Access

Identification of crucial genes and pathways associated with colorectal cancer by bioinformatics analysis

Xiaoqun Liu, Xiangdong Liu, Tiankui Qiao, Wei Chen
Pages: 1881-1889
Published online on: 09 January 2020

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Article Open Access

Clinicopathological analysis of 250 cases of pituitary adenoma under the new WHO classification

Jiayu Liu, Yuhao He, Xuebin Zhang, Xiaoling Yan, Ying Huang
Pages: 1890-1898
Published online on: 08 January 2020

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Article Open Access

Long non‑coding RNA EGFR‑AS1 sponges micorRNA‑381 to upregulate ROCK2 in bladder cancer

Shouxian Yuan, Xiuhua Luan, Haixia Chen, Xiuqing Shi, Xiangkai Zhang
Pages: 1899-1905
Published online on: 09 January 2020

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Article Open Access

Deregulation of cell adhesion molecules is associated with progression and poor outcomes in endometrial cancer: Analysis of The Cancer Genome Atlas data

Xiangjun He, Shu Lei, Qi Zhang, Liping Ma, Na Li, Jianliu Wang
Pages: 1906-1914
Published online on: 13 January 2020

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Article Open Access

Identification of candidate RNA signatures in triple‑negative breast cancer by the construction of a competing endogenous RNA network with integrative analyses of Gene Expression Omnibus and The Cancer Genome Atlas data

Ping Yan, Lingfeng Tang, Li Liu, Gang Tu
Pages: 1915-1927
Published online on: 10 January 2020

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Article Open Access

Prognostic value of key genes of the JAK‑STAT signaling pathway in patients with cutaneous melanoma

Fuqiang Pan, Qiaoqi Wang, Sizhu Li, Rui Huang, Xiangkun Wang, Xiwen Liao, Haiyan Mo, Liming Zhang, Xiang Zhou
Pages: 1928-1946
Published online on: 10 January 2020

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Article Open Access

Prognosis of ovarian clear cell cancer compared with other epithelial cancer types: A population‑based analysis

Hong Liu, Yanbo Xu, Jiali Ji, Rongrong Dong, Huiqing Qiu, Xiaolan Dai
Pages: 1947-1957
Published online on: 07 January 2020

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Article

MicroRNA‑107 may regulate lung cancer cell proliferation and apoptosis by targeting TP53 regulated inhibitor of apoptosis 1

Peng Cai, Jingjing Li, Guiming Chen, Bing Peng, Liuyang Yu, Bolin Zhao, Yi Yu
Pages: 1958-1966
Published online on: 07 January 2020

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Article

Exosomal microRNA‑210 is a potentially non‑invasive biomarker for the diagnosis and prognosis of glioma

Fengming Lan, Xiao Yue, Tingyi Xia
Pages: 1967-1974
Published online on: 07 January 2020

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Article

Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation

Yiling Zhang, Ningning Cui, Gang Zheng
Pages: 1975-1984
Published online on: 08 January 2020

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Article

Innovative analysis of distant metastasis in differentiated thyroid cancer

Danyang Chen, Lei Huang, Sichao Chen, Yihui Huang, Di Hu, Wen Zeng, Min Wang, Wei Zhou, Haifeng Feng, Wei Wei, Chao Zhang, Zeming Liu, Liang Guo
Pages: 1985-1992
Published online on: 15 January 2020

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Article

Overexpression of long non‑coding RNA cancer susceptibility 11 is involved in the development of chemoresistance to carboplatin in hepatocellular carcinoma

Haidong Liu, Tao Liu, Yong Zhou, Xinwen Song, Rendong Wei
Pages: 1993-1998
Published online on: 08 January 2020

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Article

Akt inhibitor MK‑2206 reduces pancreatic cancer cell viability and increases the efficacy of gemcitabine

Zhanshan Wang, Guangtao Luo, Zhengjun Qiu
Pages: 1999-2004
Published online on: 14 January 2020

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Article

Incidental findings in the thyroid gland on computed tomography images of the oral and maxillofacial region

Abdullah Khasawneh, Yohei Takeshita, Miki Hisatomi, Toshiyuki Kawazu, Mariko Fujita, Shunsuke Okada, Yuri Namba, Yudai Shimizu, Yoshinobu Yanagi, Junichi Asaumi
Pages: 2005-2010
Published online on: 13 January 2020

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Article

Scinderin suppresses cell proliferation and predicts the poor prognosis of hepatocellular carcinoma

Bin Zhou, Tian‑Wei Chen, Ya‑Bo Jiang, Xu‑Biao Wei, Chong‑De Lu, Jing‑Jing Li, Dong Xie, Shu‑Qun Cheng
Pages: 2011-2020
Published online on: 08 January 2020

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Article

Role of HSP27 in the multidrug sensitivity and resistance of colon cancer cells

Zhengyong Liu, Yi Liu, Yupeng Long, Baohua Liu, Xiangfeng Wang
Pages: 2021-2027
Published online on: 07 January 2020

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Article Open Access

Limited efficacy of pixantrone in refractory diffuse large B-cell lymphoma

Aleksander Novakovic, Lucka Boltezar, Barbara Jezersek Novakovic
Pages: 2028-2034
Published online on: 10 January 2020

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Article

Long non‑coding RNA LINC00152 acts as a sponge of miRNA‑193b‑3p to promote tongue squamous cell carcinoma progression

Xiuhua Li, Bing Rui, Yongbing Cao, Xiaojian Gong, Hongjiao Li
Pages: 2035-2042
Published online on: 13 January 2020

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Article

Hepatitis B virus upregulates cellular inhibitor of apoptosis protein 2 expression via the PI3K/AKT/NF‑κB signaling pathway in liver cancer

Jianping Lian, Yuanhua Zou, Ling Huang, Hao Cheng, Kai Huang, Junquan Zeng, Longhua Chen
Pages: 2043-2052
Published online on: 08 January 2020

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Article

Downregulation of extracellular vesicle microRNA‑101 derived from bone marrow mesenchymal stromal cells in myelodysplastic syndrome with disease progression

Yuu Saitoh, Tomohiro Umezu, Satoshi Imanishi, Michiyo Asano, Seiichiro Yoshizawa, Seiichiro Katagiri, Tamiko Suguro, Hiroaki Fujimoto, Daigo Akahane, Chiaki Kobayashi‑Kawana, Junko H. Ohyashiki, Kazuma Ohyashiki
Pages: 2053-2061
Published online on: 09 January 2020

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Article Open Access

Elevated expression of exosomal microRNA‑21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip

Xiaofan Pu, Guoping Ding, Mingjie Wu, Senhao Zhou, Shengnan Jia, Liping Cao
Pages: 2062-2070
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Alejandro Schcolnik‑Cabrera, Guadalupe Dominguez‑Gómez, Alma Chávez‑Blanco, Marisol Ramírez‑Yautentzi, Rocío Morales‑Bárcenas, José Díaz‑Chávez, Lucía Taja‑Chayeb, Alfonso Dueñas‑González
Pages: 2071-2071
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

Min Yong, Tinghe Yu, Si Tian, Shuaibin Liu, Jiao Xu, Jianguo Hu, Lina Hu
Pages: 2072-2072
Published online on: 09 January 2020

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Review Open Access

Lymphedema in survivors of breast cancer (Review)

Lin He, Huili Qu, Qian Wu, Yuhua Song
Pages: 2085-2096
Published online on: 16 January 2020

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Article Open Access

Curative effect of methotrexate combined with teniposide in the treatment of primary central nervous system lymphoma

Yi‑Xia Wang, Yan Huang, Xiao‑Ping Xu, Bo‑Bin Chen, Zhi‑Guang Lin, Yan Ma, Tian‑Ling Ding, Qian Wang
Pages: 2097-2106
Published online on: 22 January 2020

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Article Open Access

TSP‑1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar

Wende Yang, Wei Li, Fan Pan, Xiao‑Yan Yang, Xiaoxu Zhao, Li Qin, Yunlong Pan
Pages: 2107-2114
Published online on: 21 January 2020

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Article Open Access

HSP90AA1, ADRB2, TBL1XR1 and HSPB1 are chronic obstructive pulmonary disease‑related genes that facilitate squamous cell lung cancer progression

Lijing Wang, Hongjun Zhao, Lemeng Zhang, Hui Luo, Qiong Chen, Xiaoxia Zuo
Pages: 2115-2122
Published online on: 17 January 2020

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Article Open Access

Effect of apigenin on whole transcriptome profile of TNFα‑activated MDA‑MB‑468 triple negative breast cancer cells

David Bauer, Elizabeth Mazzio, Aaron Hilliard, Ebenezer T. Oriaku, Karam F. A. Soliman
Pages: 2123-2132
Published online on: 22 January 2020

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Article Open Access

AXIN2 and SNAIL expression predict the risk of recurrence in cutaneous squamous cell carcinoma after Mohs micrographic surgery

Guohua Zhao, Ki‑Yeol Kim, Zhenlong Zheng, Yeongjoo Oh, Dae San Yoo, Myung Eun Lee, Kee Yang Chung, Mi Ryung Roh, Zhehu Jin
Pages: 2133-2140
Published online on: 21 January 2020

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Article Open Access

High expression of interleukin‑enhancer binding factor 3 predicts poor prognosis in patients with lung adenocarcinoma

Zhangyan Xu, Hua Huang, Xing Li, Cheng Ji, Yifei Liu, Xiaojuan Liu, Jun Zhu, Zhendong Wang, Haijian Zhang, Jiahai Shi
Pages: 2141-2152
Published online on: 22 January 2020

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Article Open Access

Identification of glutathione S‑transferase π 1 as a prognostic proteomic biomarker for multiple myeloma using proteomic profiling

Jing Zhao, Meihua Wang, Pengcheng He, Ying Chen, Xiaoning Wang, Mei Zhang
Pages: 2153-2162
Published online on: 21 January 2020

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Article Open Access

ZW10 interacting kinetochore protein may serve as a prognostic biomarker for human breast cancer: An integrated bioinformatics analysis

Han‑Ning Li, Wei‑Hong Zheng, Ya‑Ying Du, Ge Wang, Meng‑Lu Dong, Zhi‑Fang Yang, Xing‑Rui Li
Pages: 2163-2174
Published online on: 24 January 2020

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Article Open Access

Integrated analysis of circular RNA‑associated ceRNA network in pancreatic ductal adenocarcinoma

Wei Song, Wen‑Jie Wang, Tao Fu, Lei Chen, Dong‑Liu Miao
Pages: 2175-2184
Published online on: 16 January 2020

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Article Open Access

Competing endogenous RNA network analysis reveals potential long non‑coding RNAs as predictive biomarkers of gastric cancer

Sanfei Peng, Xiangyang Yin, Yizheng Zhang, Wunan Mi, Tong Li, Yang Yu, Jianwu Jiang, Qi Liu, Yang Fu
Pages: 2185-2196
Published online on: 24 January 2020

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Article Open Access

Analysis of the methylation of CpG islands in the CDO1, TAC1 and CHFR genes in pancreatic ductal cancer

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Simple scoring system for prediction of hepatocellular carcinoma occurrence after hepatitis C virus eradication by direct‑acting antiviral treatment: All Kagawa Liver Disease Group Study

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MicroRNA‑22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c‑Myc binding protein, and the subsequent reduction in hTERT expression

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Long non‑coding (lnc)RNA PAPAS overexpression inhibits tumor growth in papillary thyroid carcinoma by downregulating lncRNA HOTTIP

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γ‑Klotho is correlated with resistance to docetaxel in castration‑resistant prostate cancer

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Clinicopathological characteristics and genetic analysis of pulmonary carcinoid tumors: A single‑center retrospective cohort study and literature review

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Association between interleukin‑36γ and tumor progression in non‑small cell lung cancer

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CDCA2 acts as an oncogene and induces proliferation of clear cell renal cell carcinoma cells

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Long non‑coding RNA ELF3‑antisense RNA 1 promotes osteosarcoma cell proliferation by upregulating Kruppel‑like factor 12 potentially via methylation of the microRNA‑205 gene

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PD‑L1 expression in malignant melanomas of the skin and gastrointestinal tract

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Long noncoding RNA PLAC2 regulates PTEN in retinoblastoma and participates in the regulation of cancer cell apoptosis

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C‑X‑C motif receptor 3A enhances proliferation and invasiveness of colorectal cancer cells, and is mediated by C‑X‑C motif ligand 10

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Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine

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Stereotactic body radiotherapy feasibility for patients with peripheral stage Ι lung cancer and poor pulmonary function

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Triple negative endometrial cancer: Incidence and prognosis in a monoinstitutional series of 220 patients

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Changes of serum miR-223-3p in patients with oral cancer treated with TPF regimen and the prognosis

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Pages: 2527-2532
Published online on: 24 January 2020

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Effect of nalbuphine on patient controlled intravenous analgesia after radical resection of colon cancer

Qi Jiang, Rongfang Zhang, Tao Liu
Pages: 2533-2538
Published online on: 24 January 2020

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Efficacy analysis of trastuzumab, carboplatin and docetaxel in HER‑2‑positive breast cancer patients

Di Wu, Liangfa Xiong
Pages: 2539-2546
Published online on: 24 January 2020

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Long-chain non-coding RNA GACAT1 promotes development and progression of breast cancer by targeting microRNA-875-3p

Qinghua Wang, Jie Xue, Qingfang Ren, Xiaona Li, Xiaoli Qiu
Pages: 2547-2553
Published online on: 24 January 2020

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Clinical efficacy of platelet transfusion therapy in patients with leukemia and analysis of risk factors for ineffective transfusion

Li Chen, Hao Zhou, Bo Guo , Zheng Guan
Pages: 2554-2561
Published online on: 24 January 2020

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Article

Correlation of APOBEC3G expression with liver function indexes of patients with chronic hepatitis B and comparison in chronic hepatitis B, liver cirrhosis and liver cancer

Lina Ni, Chuanbao Li, Yingbo Li
Pages: 2562-2567
Published online on: 24 January 2020

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Effect of miR‑205 on proliferation and migration of thyroid cancer cells by targeting CCNB2 and the mechanism

Xin Wang, Haomin Zhang, Kai Jiao, Chunyang Zhao, Hailong Liu, Qinghong Meng, Zhao Wang, Chunling Feng, Yuanchun Li
Pages: 2568-2574
Published online on: 24 January 2020

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CiteScore Rank: Q2: #178/415 Oncology

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
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Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
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Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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