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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2020 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis (Review)

Magdalena Ciążyńska, Igor A. Bednarski, Karolina Wódz, Joanna Narbutt, Aleksandra Lesiak
Pages: 1649-1656
Published online on: 09 January 2020

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Review Open Access

FBW7 in hematological tumors (Review)

Qiaojuan Zhu, Linjun Hu, Yang Guo, Zunqiang Xiao, Qiuran Xu, Xiangmin Tong
Pages: 1657-1664
Published online on: 08 January 2020

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Article Open Access

Aquaporin 5 promotes tumor migration and angiogenesis in non‑small cell lung cancer cell line H1299

Abdalkhalig Elkhider, Bing Wang, Xunli Ouyang, Mahmoud Al‑Azab, Williams Walana, Xiaotong Sun, Han Li, Yawei Tang, Jing Wei, Xia Li
Pages: 1665-1672
Published online on: 07 January 2020

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Article Open Access

Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers

Shou‑Feng Zhao, Xue‑Jing Yin, Wen‑Ju Zhao, Le‑Cui Liu, Zhi‑Peng Wang
Pages: 1673-1682
Published online on: 08 January 2020

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Article Open Access

THBS2, a microRNA‑744‑5p target, modulates MMP9 expression through CUX1 in pancreatic neuroendocrine tumors

Heng Jiao, Lingxiao Zeng, Jianpeng Zhang, Shengsheng Yang, Wenhui Lou
Pages: 1683-1692
Published online on: 09 January 2020

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Article Open Access

PTPN11 hypomethylation is associated with gastric cancer progression

Lele Xu, Cong Zhou, Ranran Pan, Junjian Tang, Jinzhi Wang, Bin Li, Tianyi Huang, Shiwei Duan, Chunfang Xu
Pages: 1693-1700
Published online on: 07 January 2020

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Article Open Access

Role of Bcl‑2 on drug resistance in breast cancer polyploidy‑induced spindle poisons

Bibo Yuan, Juan Hao, Qian Zhang, Yan Wang, Yu Zhu
Pages: 1701-1710
Published online on: 07 January 2020

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Article Open Access

High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma

Liuping Luo, Lihong Chen, Kun Ke, Bixing Zhao, Lili Wang, Cuilin Zhang, Fei Wang, Naishun Liao, Xiaoyuan Zheng, Xiaolong Liu, Yingchao Wang, Jingfeng Liu
Pages: 1711-1720
Published online on: 13 January 2020

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Article Open Access

Prognostic significance of the sub-classification of stage pT3a renal tumors by perinephric and sinus fat invasion

Dongsheng Zhu, Jingyuan Cao, Chao Zhi, Tao Guo, Yuhong Li, Zhiqiang Lang, Gang Li
Pages: 1721-1726
Published online on: 09 January 2020

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Article Open Access

Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance

Tingting Wang, Xiaoyan Lv, Shen Jiang, Shaorong Han, Yanming Wang
Pages: 1727-1734
Published online on: 09 January 2020

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Article Open Access

Increased ski expression levels are associated with a higher risk and poor prognosis in patients with gastrointestinal stromal tumors

Qiu‑Shi Wang, Yu Zhai, Ping Li, Hua‑Liang Xiao, Yuan‑Guo Zhou
Pages: 1735-1740
Published online on: 09 January 2020

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Article Open Access

Diffuse mesothelin expression leads to worse prognosis through enhanced cellular proliferation in colorectal cancer

Satoshi Inoue, Takumi Tsunoda, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Ira Pastan, Kunio Kasugai, Kenji Kasai, Hiroshi Ikeda, Shingo Inaguma
Pages: 1741-1750
Published online on: 10 January 2020

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Article Open Access

Overexpression of miR‑206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases

Xiongfeng Xu, Bo Qiu, Peng Yi, Huajie Li
Pages: 1751-1758
Published online on: 08 January 2020

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Article Open Access

IRF1 association with tumor immune microenvironment and use as a diagnostic biomarker for colorectal cancer recurrence

Yanfang Wu, Shuju Zhang, Jun Yan
Pages: 1759-1770
Published online on: 10 January 2020

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Article Open Access

Fatty acid‑binding protein 5 predicts poor prognosis in patients with uveal melanoma

Yue Xu, Wen‑Hao Xu, Xiao‑Long Yang, Hai‑Liang Zhang, Xiao‑Feng Zhang
Pages: 1771-1780
Published online on: 14 January 2020

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Article Open Access

Comparative mutational analysis of distal colon cancer with rectal cancer

Zhiyong Zhang, Aili Wang, Xuan Tang, Ying Chen, Erjiang Tang, Huihong Jiang
Pages: 1781-1788
Published online on: 08 January 2020

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Article Open Access

Expression pattern of p‑Smad2/Smad4 as a predictor of survival in invasive breast ductal carcinoma

Nannan Liu, Dongxue Qi, Jing Jiang, Jihong Zhang, Chunyan Yu
Pages: 1789-1798
Published online on: 13 January 2020

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Article Open Access

The oncogenic role of microRNA‑500a in colorectal cancer

Yang Li, Zhong Chen
Pages: 1799-1805
Published online on: 10 January 2020

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Article Open Access

MicroRNA‑139‑5p inhibits cell viability, migration and invasion and suppresses tumor growth by targeting HDGF in non‑small cell lung cancer Retraction in /10.3892/ol.2023.14090

Zuxiong Zhang, Weizhi Li, Damei Jiang, Chi Liu, Zhenghong Lai
Pages: 1806-1814
Published online on: 13 January 2020

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Article Open Access

High expression of citron kinase predicts poor prognosis of prostate cancer

Junnan Liu, Jianguo Dou, Wujiao Wang, Hengchuan Liu, Yunlang Qin, Qixin Yang, Wencheng Jiang, Yong Liang, Yuejiang Liu, Jiang He, Li Mai, Ying Li, Delin Wang
Pages: 1815-1823
Published online on: 07 January 2020

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Article Open Access

Total flavonoids suppress lung cancer growth via the COX‑2‑mediated Wnt/β‑catenin signaling pathway Retraction in /10.3892/ol.2024.14212

Lei Han, Shu Fang, Guangtao Li, Minghuan Wang, Renzhi Yu
Pages: 1824-1830
Published online on: 09 January 2020

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Article Open Access

Distinct expression and prognostic values of the replication protein A family in gastric cancer

Yujie Zhang, Chaoran Yu
Pages: 1831-1841
Published online on: 07 January 2020

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Article Open Access

Expression and clinical significance of MAPK and EGFR in triple‑negative breast cancer

Weihua Jiang, Xiaowen Wang, Chenguang Zhang, Laiti Xue, Liang Yang
Pages: 1842-1848
Published online on: 09 January 2020

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Article Open Access

Long non‑coding RNA‑ZNF281 promotes cancer cell migration and invasion in gastric cancer via downregulation of microRNA‑124

Hengling Gao, Peizhe Li, Yingrui Hei, Shuliang Li, Jinkai Wang, Xukun Lv, Jianxian Zhang
Pages: 1849-1855
Published online on: 10 January 2020

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Article Open Access

ADAM9: A novel player in vestibular schwannoma pathogenesis

Maria Breun, Alexandra Schwerdtfeger, Donato Daniel Martellotta, Almuth F. Kessler, Camelia M. Monoranu, Cordula Matthies, Mario Löhr, Carsten Hagemann
Pages: 1856-1864
Published online on: 14 January 2020

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Article Open Access

Quantitative analysis of metabolic parameters at 18F‑fluorodeoxyglucose positron emission tomography in predicting malignant potential of anterior mediastinal tumors

Toshiki Yajima, Akira Mogi, Kimihiro Shimizu, Takayuki Kosaka, Yoichi Ohtaki, Kai Obayashi, Seshiru Nakazawa, Takahito Nakajima, Yoshito Tsushima, Ken Shirabe
Pages: 1865-1871
Published online on: 09 January 2020

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Article Open Access

Pharmacokinetic evaluation and antitumor potency of liposomal nanoparticle encapsulated cisplatin targeted to CD24‑positive cells in ovarian cancer

Keisuke Ashihara, Yoshito Terai, Tomohito Tanaka, Yoshimichi Tanaka, Satoe Fujiwara, Kazuya Maeda, Satoshi Tunetoh, Hiroshi Sasaki, Masami Hayashi, Masahide Ohmichi
Pages: 1872-1880
Published online on: 09 January 2020

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Article Open Access

Identification of crucial genes and pathways associated with colorectal cancer by bioinformatics analysis

Xiaoqun Liu, Xiangdong Liu, Tiankui Qiao, Wei Chen
Pages: 1881-1889
Published online on: 09 January 2020

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Article Open Access

Clinicopathological analysis of 250 cases of pituitary adenoma under the new WHO classification

Jiayu Liu, Yuhao He, Xuebin Zhang, Xiaoling Yan, Ying Huang
Pages: 1890-1898
Published online on: 08 January 2020

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Article Open Access

Long non‑coding RNA EGFR‑AS1 sponges micorRNA‑381 to upregulate ROCK2 in bladder cancer

Shouxian Yuan, Xiuhua Luan, Haixia Chen, Xiuqing Shi, Xiangkai Zhang
Pages: 1899-1905
Published online on: 09 January 2020

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Article Open Access

Deregulation of cell adhesion molecules is associated with progression and poor outcomes in endometrial cancer: Analysis of The Cancer Genome Atlas data

Xiangjun He, Shu Lei, Qi Zhang, Liping Ma, Na Li, Jianliu Wang
Pages: 1906-1914
Published online on: 13 January 2020

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Article Open Access

Identification of candidate RNA signatures in triple‑negative breast cancer by the construction of a competing endogenous RNA network with integrative analyses of Gene Expression Omnibus and The Cancer Genome Atlas data

Ping Yan, Lingfeng Tang, Li Liu, Gang Tu
Pages: 1915-1927
Published online on: 10 January 2020

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Article Open Access

Prognostic value of key genes of the JAK‑STAT signaling pathway in patients with cutaneous melanoma

Fuqiang Pan, Qiaoqi Wang, Sizhu Li, Rui Huang, Xiangkun Wang, Xiwen Liao, Haiyan Mo, Liming Zhang, Xiang Zhou
Pages: 1928-1946
Published online on: 10 January 2020

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Article Open Access

Prognosis of ovarian clear cell cancer compared with other epithelial cancer types: A population‑based analysis

Hong Liu, Yanbo Xu, Jiali Ji, Rongrong Dong, Huiqing Qiu, Xiaolan Dai
Pages: 1947-1957
Published online on: 07 January 2020

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Article

MicroRNA‑107 may regulate lung cancer cell proliferation and apoptosis by targeting TP53 regulated inhibitor of apoptosis 1

Peng Cai, Jingjing Li, Guiming Chen, Bing Peng, Liuyang Yu, Bolin Zhao, Yi Yu
Pages: 1958-1966
Published online on: 07 January 2020

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Article

Exosomal microRNA‑210 is a potentially non‑invasive biomarker for the diagnosis and prognosis of glioma

Fengming Lan, Xiao Yue, Tingyi Xia
Pages: 1967-1974
Published online on: 07 January 2020

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Article

Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation

Yiling Zhang, Ningning Cui, Gang Zheng
Pages: 1975-1984
Published online on: 08 January 2020

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Article

Innovative analysis of distant metastasis in differentiated thyroid cancer

Danyang Chen, Lei Huang, Sichao Chen, Yihui Huang, Di Hu, Wen Zeng, Min Wang, Wei Zhou, Haifeng Feng, Wei Wei, Chao Zhang, Zeming Liu, Liang Guo
Pages: 1985-1992
Published online on: 15 January 2020

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Article

Overexpression of long non‑coding RNA cancer susceptibility 11 is involved in the development of chemoresistance to carboplatin in hepatocellular carcinoma

Haidong Liu, Tao Liu, Yong Zhou, Xinwen Song, Rendong Wei
Pages: 1993-1998
Published online on: 08 January 2020

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Article

Akt inhibitor MK‑2206 reduces pancreatic cancer cell viability and increases the efficacy of gemcitabine

Zhanshan Wang, Guangtao Luo, Zhengjun Qiu
Pages: 1999-2004
Published online on: 14 January 2020

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Article

Incidental findings in the thyroid gland on computed tomography images of the oral and maxillofacial region

Abdullah Khasawneh, Yohei Takeshita, Miki Hisatomi, Toshiyuki Kawazu, Mariko Fujita, Shunsuke Okada, Yuri Namba, Yudai Shimizu, Yoshinobu Yanagi, Junichi Asaumi
Pages: 2005-2010
Published online on: 13 January 2020

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Article

Scinderin suppresses cell proliferation and predicts the poor prognosis of hepatocellular carcinoma

Bin Zhou, Tian‑Wei Chen, Ya‑Bo Jiang, Xu‑Biao Wei, Chong‑De Lu, Jing‑Jing Li, Dong Xie, Shu‑Qun Cheng
Pages: 2011-2020
Published online on: 08 January 2020

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Article

Role of HSP27 in the multidrug sensitivity and resistance of colon cancer cells

Zhengyong Liu, Yi Liu, Yupeng Long, Baohua Liu, Xiangfeng Wang
Pages: 2021-2027
Published online on: 07 January 2020

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Article Open Access

Limited efficacy of pixantrone in refractory diffuse large B-cell lymphoma

Aleksander Novakovic, Lucka Boltezar, Barbara Jezersek Novakovic
Pages: 2028-2034
Published online on: 10 January 2020

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Article

Long non‑coding RNA LINC00152 acts as a sponge of miRNA‑193b‑3p to promote tongue squamous cell carcinoma progression

Xiuhua Li, Bing Rui, Yongbing Cao, Xiaojian Gong, Hongjiao Li
Pages: 2035-2042
Published online on: 13 January 2020

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Article

Hepatitis B virus upregulates cellular inhibitor of apoptosis protein 2 expression via the PI3K/AKT/NF‑κB signaling pathway in liver cancer

Jianping Lian, Yuanhua Zou, Ling Huang, Hao Cheng, Kai Huang, Junquan Zeng, Longhua Chen
Pages: 2043-2052
Published online on: 08 January 2020

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Article

Downregulation of extracellular vesicle microRNA‑101 derived from bone marrow mesenchymal stromal cells in myelodysplastic syndrome with disease progression

Yuu Saitoh, Tomohiro Umezu, Satoshi Imanishi, Michiyo Asano, Seiichiro Yoshizawa, Seiichiro Katagiri, Tamiko Suguro, Hiroaki Fujimoto, Daigo Akahane, Chiaki Kobayashi‑Kawana, Junko H. Ohyashiki, Kazuma Ohyashiki
Pages: 2053-2061
Published online on: 09 January 2020

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Article Open Access

Elevated expression of exosomal microRNA‑21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip

Xiaofan Pu, Guoping Ding, Mingjie Wu, Senhao Zhou, Shengnan Jia, Liping Cao
Pages: 2062-2070
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Alejandro Schcolnik‑Cabrera, Guadalupe Dominguez‑Gómez, Alma Chávez‑Blanco, Marisol Ramírez‑Yautentzi, Rocío Morales‑Bárcenas, José Díaz‑Chávez, Lucía Taja‑Chayeb, Alfonso Dueñas‑González
Pages: 2071-2071
Published online on: 15 January 2020

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Correction Open Access

[Corrigendum] DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

Min Yong, Tinghe Yu, Si Tian, Shuaibin Liu, Jiao Xu, Jianguo Hu, Lina Hu
Pages: 2072-2072
Published online on: 09 January 2020

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Review Open Access

Lymphedema in survivors of breast cancer (Review)

Lin He, Huili Qu, Qian Wu, Yuhua Song
Pages: 2085-2096
Published online on: 16 January 2020

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Article Open Access

Curative effect of methotrexate combined with teniposide in the treatment of primary central nervous system lymphoma

Yi‑Xia Wang, Yan Huang, Xiao‑Ping Xu, Bo‑Bin Chen, Zhi‑Guang Lin, Yan Ma, Tian‑Ling Ding, Qian Wang
Pages: 2097-2106
Published online on: 22 January 2020

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Article Open Access

TSP‑1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar

Wende Yang, Wei Li, Fan Pan, Xiao‑Yan Yang, Xiaoxu Zhao, Li Qin, Yunlong Pan
Pages: 2107-2114
Published online on: 21 January 2020

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Article Open Access

HSP90AA1, ADRB2, TBL1XR1 and HSPB1 are chronic obstructive pulmonary disease‑related genes that facilitate squamous cell lung cancer progression

Lijing Wang, Hongjun Zhao, Lemeng Zhang, Hui Luo, Qiong Chen, Xiaoxia Zuo
Pages: 2115-2122
Published online on: 17 January 2020

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Article Open Access

Effect of apigenin on whole transcriptome profile of TNFα‑activated MDA‑MB‑468 triple negative breast cancer cells

David Bauer, Elizabeth Mazzio, Aaron Hilliard, Ebenezer T. Oriaku, Karam F. A. Soliman
Pages: 2123-2132
Published online on: 22 January 2020

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Article Open Access

AXIN2 and SNAIL expression predict the risk of recurrence in cutaneous squamous cell carcinoma after Mohs micrographic surgery

Guohua Zhao, Ki‑Yeol Kim, Zhenlong Zheng, Yeongjoo Oh, Dae San Yoo, Myung Eun Lee, Kee Yang Chung, Mi Ryung Roh, Zhehu Jin
Pages: 2133-2140
Published online on: 21 January 2020

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Article Open Access

High expression of interleukin‑enhancer binding factor 3 predicts poor prognosis in patients with lung adenocarcinoma

Zhangyan Xu, Hua Huang, Xing Li, Cheng Ji, Yifei Liu, Xiaojuan Liu, Jun Zhu, Zhendong Wang, Haijian Zhang, Jiahai Shi
Pages: 2141-2152
Published online on: 22 January 2020

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Article Open Access

Identification of glutathione S‑transferase π 1 as a prognostic proteomic biomarker for multiple myeloma using proteomic profiling

Jing Zhao, Meihua Wang, Pengcheng He, Ying Chen, Xiaoning Wang, Mei Zhang
Pages: 2153-2162
Published online on: 21 January 2020

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Article Open Access

ZW10 interacting kinetochore protein may serve as a prognostic biomarker for human breast cancer: An integrated bioinformatics analysis

Han‑Ning Li, Wei‑Hong Zheng, Ya‑Ying Du, Ge Wang, Meng‑Lu Dong, Zhi‑Fang Yang, Xing‑Rui Li
Pages: 2163-2174
Published online on: 24 January 2020

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Article Open Access

Integrated analysis of circular RNA‑associated ceRNA network in pancreatic ductal adenocarcinoma

Wei Song, Wen‑Jie Wang, Tao Fu, Lei Chen, Dong‑Liu Miao
Pages: 2175-2184
Published online on: 16 January 2020

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Article Open Access

Competing endogenous RNA network analysis reveals potential long non‑coding RNAs as predictive biomarkers of gastric cancer

Sanfei Peng, Xiangyang Yin, Yizheng Zhang, Wunan Mi, Tong Li, Yang Yu, Jianwu Jiang, Qi Liu, Yang Fu
Pages: 2185-2196
Published online on: 24 January 2020

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Article Open Access

Analysis of the methylation of CpG islands in the CDO1, TAC1 and CHFR genes in pancreatic ductal cancer

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Simple scoring system for prediction of hepatocellular carcinoma occurrence after hepatitis C virus eradication by direct‑acting antiviral treatment: All Kagawa Liver Disease Group Study

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Long non‑coding (lnc)RNA PAPAS overexpression inhibits tumor growth in papillary thyroid carcinoma by downregulating lncRNA HOTTIP

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γ‑Klotho is correlated with resistance to docetaxel in castration‑resistant prostate cancer

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CDCA2 acts as an oncogene and induces proliferation of clear cell renal cell carcinoma cells

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Long non‑coding RNA ELF3‑antisense RNA 1 promotes osteosarcoma cell proliferation by upregulating Kruppel‑like factor 12 potentially via methylation of the microRNA‑205 gene

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PD‑L1 expression in malignant melanomas of the skin and gastrointestinal tract

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Long noncoding RNA PLAC2 regulates PTEN in retinoblastoma and participates in the regulation of cancer cell apoptosis

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C‑X‑C motif receptor 3A enhances proliferation and invasiveness of colorectal cancer cells, and is mediated by C‑X‑C motif ligand 10

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Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine

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Inhibiting the Src/STAT3 signaling pathway contributes to the anti‑melanoma mechanisms of dioscin

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Stereotactic body radiotherapy feasibility for patients with peripheral stage Ι lung cancer and poor pulmonary function

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Triple negative endometrial cancer: Incidence and prognosis in a monoinstitutional series of 220 patients

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Changes of serum miR-223-3p in patients with oral cancer treated with TPF regimen and the prognosis

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Pages: 2527-2532
Published online on: 24 January 2020

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Effect of nalbuphine on patient controlled intravenous analgesia after radical resection of colon cancer

Qi Jiang, Rongfang Zhang, Tao Liu
Pages: 2533-2538
Published online on: 24 January 2020

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Efficacy analysis of trastuzumab, carboplatin and docetaxel in HER‑2‑positive breast cancer patients

Di Wu, Liangfa Xiong
Pages: 2539-2546
Published online on: 24 January 2020

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Long-chain non-coding RNA GACAT1 promotes development and progression of breast cancer by targeting microRNA-875-3p

Qinghua Wang, Jie Xue, Qingfang Ren, Xiaona Li, Xiaoli Qiu
Pages: 2547-2553
Published online on: 24 January 2020

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Article

Clinical efficacy of platelet transfusion therapy in patients with leukemia and analysis of risk factors for ineffective transfusion

Li Chen, Hao Zhou, Bo Guo , Zheng Guan
Pages: 2554-2561
Published online on: 24 January 2020

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Correlation of APOBEC3G expression with liver function indexes of patients with chronic hepatitis B and comparison in chronic hepatitis B, liver cirrhosis and liver cancer

Lina Ni, Chuanbao Li, Yingbo Li
Pages: 2562-2567
Published online on: 24 January 2020

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Effect of miR‑205 on proliferation and migration of thyroid cancer cells by targeting CCNB2 and the mechanism

Xin Wang, Haomin Zhang, Kai Jiao, Chunyang Zhao, Hailong Liu, Qinghong Meng, Zhao Wang, Chunling Feng, Yuanchun Li
Pages: 2568-2574
Published online on: 24 January 2020

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Ivonescimab combined with radiotherapy in the treatment of advanced lung adenocarcinoma with high expression of PD‑L1: A case report

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Published online on: 02 October 2026

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Association between antidepressant exposure and prognosis in breast cancer: A systematic review and meta‑analysis

Qisong Chen, Yihan Shen, Xiaoming Zhang, Ting Jiang, Shiyan Zhang, Xinyan Yu, Feng Hong
Article Number: 537
Published online on: 02 October 2026

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Review Open Access

Brain‑derived neurotrophic factor in solid tumor angiogenesis and neurovascular‑immune interactions (Review)

Guoqing Zhu, Dianliang Zhang, Hao Wang, Sen Yan, Mingchao Ni, Shangkun Ning, Chong Wang, Mei Liu, Jibing Liu
Article Number: 536
Published online on: 01 October 2026

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hnRNPC promotes oral squamous cell carcinoma progression via N6‑methyladenosine‑dependent stabilization of BCAT1 to enhance branched‑chain amino acid metabolism

Zhixin Zhang, Xin Gao, Ting Han, Fei Chai, Menghui Gao, Yulin An
Article Number: 535
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Expression of Concern Open Access

[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

Xiu Xiu Jiang, Kai Hong Xu, Jun Yan Ma, Yong Hong Tian, Xiao Yan Guo, Jun Lin, Rui Jin Wu
Article Number: 534
Published online on: 30 September 2026

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Case Report Open Access

A thoracic SMARCA4‑deficient undifferentiated tumor: A case report

Xiaocheng Wang, Miao Chen, Mingzhe Wang, Chengjun Ban, Lishan Zhang, Heng Zou, Hongwu Wang, Bing Yang
Article Number: 533
Published online on: 29 September 2026

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Case Report Open Access

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo‑immunotherapy: A case report

Zijian Qiu, Feng Xuan, Xi Mao, Peipei Yang, Xiaoping Zhu
Article Number: 532
Published online on: 29 September 2026

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Single‑cell transcriptomics identifies PRDX1 and GPX4 as potential ferroptosis regulators and tumor microenvironment‑­related molecules in hepatocellular carcinoma

Zhou Zhang, Hui Chen, Chen Qian, Ningning Yang, Zijing Liu, Ruirui Yang
Article Number: 531
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Expression of Concern Open Access

[Expression of Concern] Interferon‑α suppresses invasion and enhances cisplatin‑mediated apoptosis and autophagy in human osteosarcoma cells

Jun Zhao, Mingli Wang, Zeng Li, Jingxian Chen, Zongshen Yin, Jun Chang, Dongmei Gao, Shiping Wang
Article Number: 530
Published online on: 28 September 2026

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Article Open Access

KRT14 activated by transcription factor E2F1 promotes bladder cancer progression

Xingheng Chen, Sinan Liu, Xiaosong Zhang, Xiang Chen, Chenlu Wang
Article Number: 529
Published online on: 24 September 2026

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Review Open Access

Research progress of pancreatic cancer based on ferroptosis‑cuproptosis interaction (Review)

Wenqing Liu, Minglu Ding, Ruijiao Ji, Zhenmin Qiao, Ran Liu, Peijian Chen, Lantao Liu
Article Number: 528
Published online on: 24 September 2026

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Correction Open Access

[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Article Number: 527
Published online on: 24 September 2026

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Case Report Open Access

Therapy‑related acute myeloid leukemia with a rare complex karyotype following first‑line therapy for small cell lung cancer: A case report

Lin Luo, Sha Yu
Article Number: 526
Published online on: 23 September 2026

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Article Open Access

Netupitant‑palonosetron combined with dexamethasone for preventing chemotherapy‑induced nausea and vomiting in high‑risk patients with colorectal cancer receiving moderately emetogenic chemotherapy: A retrospective study

Jiwen Fan, Wenjuan Lai, Boran Cheng, Meijing Chen, Jing Gao, Shubin Wang, Gangling Tong
Article Number: 525
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] Upregulation of H19 promotes invasion and induces epithelial‑to‑mesenchymal transition in esophageal cancer

Cheng Huang, Lihua Cao, Limin Qiu, Xiaoli Dai, Linwei Ma, Yingting Zhou, Huifen Li, Min Gao, Weiyong Li, Qing Zhang, Koulan Han, Hongzhen Lv
Article Number: 524
Published online on: 23 September 2026

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Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Article Open Access

Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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Journal Cover
December-2026 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Bulk and single‑cell analysis of FAM72D reveals its prognostic and functional relevance in hepatocellular carcinoma

Cuihao Zhao, Quliyang Yin, Jianfeng Yu, Weiqi Duan, Yufeng Li, Qian Jian
Article Number: 546
Published online on: 12 October 2026

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Article Open Access

Serum metabolomic signatures associated with gastric signet‑ring cell carcinoma: A dual‑platform mass spectrometry study

Huiling Cao, Shuwei Guo, Jinchang Li, Yuying Bian, Jianjiang Shen, Jia Wang, Fei Meng, Wenlu Sun, Qingmin Sun, Wanjian Gu
Article Number: 545
Published online on: 09 October 2026

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Case Report Open Access

Drug‑eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report

Yin Gao, Qiang Xu, Dongxu Kang, Longzhen Piao
Article Number: 544
Published online on: 08 October 2026

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Case Report Open Access

Unexpected favorable response of stage IV gastric adenocarcinoma to sintilimab combined with chemotherapy: A case report

Jian Han, Zhe Zhu, Liang Huang, Liang Zhuang, Lihong Zhang, Yixin Tong, Chao Zhang, Hanlin Mu, Huaping Xie
Article Number: 543
Published online on: 08 October 2026

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Correction Open Access

[Corrigendum] Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Yawei Shi, Yang Zhao, Nan Shao, Runyi Ye, Yin Lin, Ning Zhang, Wen Li, Yunjian Zhang, Shenming Wang
Article Number: 542
Published online on: 08 October 2026

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Article Open Access

Potential of clinical staging for long‑term prognosis prediction in pathological stage III gastric cancer

Naosuke Nakamichi, Hiroyuki Inoue, Takeshi Kubota, Toshiyuki Kosuga, Keiji Nishibeppu, Kazuya Takabatake, Shutaro Sumiyoshi, Junichi Hamada, Kento Kurashima, Hidemasa Kubo, Jun Kiuchi, Taisuke Imamura, Kenji Nanishi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Hitoshi Fujiwara, Toshiya Ochiai, Atsushi Shiozaki
Article Number: 541
Published online on: 07 October 2026

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Article Open Access

NOL11 is a novel prognostic biomarker associated with immune infiltration and tumor progression in hepatocellular carcinoma

Hong Xie, Shengnan Wang, Xiaoyan Sheng, Lei Ye
Article Number: 540
Published online on: 07 October 2026

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Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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